Melatonin Protocol for COVID-19

Art,

How does one take melatonin throughout the day without falling asleep? Melatonin knocks me out at night, I can't imagine taking it during the day and being functional.

Hi Kristine,

I have answered this questions a few times and that answer would be in the link to the original post in my reply to you.

Melatonin is known for what is often referred to as the "melatonin hangover" which I assume you are referring to. For many people, this issue diminishes with regular use as the body adjusts to increased melatonin.

As far as I know, Dr. Neel only prescribes melatonin for Covid-19 when you get symptoms and test positive. Under those circumstances he starts his patients at 1 mg per kilogram of body weight. So essentially he does not give it to you until he knows you are sick. Once you are sick with Covid-19, you shouldn't be going anywhere outside of your home as you are contagious. That means you should be spending the majority of your time at home in bed resting and good sleep with Covid-19 is rare. So imo, actually getting more restful sleep is a good thing and melatonin is known for helping to get people to REM sleep where your body is able to do more repair than in non REM sleep.

Lastly, Covid-19 is deadly in some people, so would I really be worried about if I felt tired or not in order to take melatonin? My answer is no and that should be the least of my worries with a known deadly disease! Keep in mind that melatonin has a better safety profile than any drug currently being used to treat Covid-19 and melatonin has shown in one study to improve outcomes for patients on a ventilator. No other Covid-19 specific drug that I am aware of can do that!

So for people who are "very worried" about feeling tired if they take melatonin for Covid-19, perhaps the answer is to skip melatonin and go with something like Hydroxychloroquine, Remdesivir or Favipiravir which all do poorly in late stage Covid-19 disease and nobody is really even talking about these drugs any more for Covid-19 because the available studies and results for them are nothing to get excited about.

Art

Art, can you take high dose melatonin prophylactically? My DinL was just sent home with sniffles and headache, was told to get tested. She got the test, but it's 5 days for result. Should she start high dose now? Or wait until it's positive? I'd say now, since covid is a virus. She's a little bitty thing, maybe 105 pounds, but her overall diet is not great.

GertJr,

I'm not a doctor so I can't tell anyone else what to do or take.

Dr. Neel is recommending to other doctors and his patients, 1 mg of melatonin for each kilogram of body weight. If she weighs 105 lbs, that is equivalent to just under 48 kilos.

For myself, I would start at the first symptom and stop if the test comes back negative, but I am not recommending that anyone do what I do.

Art

Thanks, Art. That's what I told her to do. She already had melatonin, so just took enough to add up to that amount and divvied it up into 4 doses. She started that yesterday as soon as she got home (sent home from work, stopped to get tested) and is, today, up and about like nothing happened. They're harvesting around us, so lots of dust in the air and she thinks she was just reacting to that. Probably.

Just a post in support of Art's last post on Melatonin. I also think it's worth mentioning that the Chinese researchers quickly confirmed the efficacy and safety of Melatonin for COVID-19 as far back as March this year and, unlike the Western researchers and the FDA, they wasted no time implementing its rapid use in their hospitals. Here is the Chinese research:

https://pubmed.ncbi.nlm.nih.gov/32217117/

China has also donated and shipped large amounts of drugs/herbs to the Philippines (where I live). They shipped Lianhua Qingwen (a COVID-19 anti-viral) and Melatonin as well as other drug/herbal combinations to be used in Filipino hospitals. The Philippine researchers have also wasted no time confirming the efficacy and safety of Melatonin which can easily be purchased from any Asian retailer website like Alibaba and Lazada.

Unfortunately, as Art and I have discovered, Chinese anti-viral herbs like Lianhua Qingwen capsules are not being sold on Amazon (banned by Jeff Bezos?) but they are sold on eBay. So now Amazon has been politicized in support of all that China-hate from all western govts, which is a great shame.

It also appears to me that the perpetration of all that China-hate propaganda in the western media seems to be way more important (sic) than western researchers actually knuckling down and making the effort to find a successful and consistent therapeutic anti-viral cure (with a 95% cure rate) for COVID-19 in order to save lives in the West. That's the way to go, not vaccines. And China is already there with her integrated medicine approach (but this has not being accurately reported or recognized in the West because of all the continual China-hate propaganda emanating from western, govt-led media who are so successfully blurring, distorting or just not reporting all the facts).

Mary Lou, how are you feeling now?

Yes, I am wondering how Mary Lou is doing also? She hasn't updated yet.

Art

I do not have COVID 19 but have had bowel problems for a very long time due to so much anti biotic use over the years for COPD. Recently I switched over to Lauricidin ( a concentrated coconut oil pellet) that I slowly worked up from a 6 count pellet in a scoop to a full scoop., 3xs a day at meals. I can't tell you how much better I feel. Don't have to always keep the bathroom in my sights when going out. Bowels are returning to normal. The micro biome is where we all need to start in our desire to be healthy. Hope this sheds some light on your situation. Carol

Hi Art,

I'm not surprised at him using melatonin. Like many things about this administration, it's one rule for them and another for the hoi polloi. Maybe now some people will realize that masks work.

Maybe he made them read EarthClinic yesterday.

https://www.youtube.com/watch?v=prujdWuCxa8

Fauci: Masks don't work

Trump did finish a two-week trial of hydroxychloroquine in May, probably as a prophylactic because it showed promising results in early studies. Of course we now are aware of more possible therapeutics such as melatonin and vitamin D due to more research. But he's not advocating the use of a particular drug now, after HCQ has become politicized.

Art,

I just tested positive for Covid and I am assuming my infection date was 9/4/2020. I didn't get the test results until 9/6/2020.

I'm 68 years old and in very good health. I do not take any medications and have never had a surgery. I currently (9/8/2020) have very mild symptoms, mostly sinus congestion, head cold feeling, mild headache and exhaustion.

I just ordered Melatonin and will place another order for sublingual melatonin as I believe I read that was preferred.

I've read all the articles that I could and the comments. Several of the lengthy ones I had to skip. I can't focus on complex explanations right now.

I see in the article about Country Life Assisted Living that they supplemented with Vitamin D3, Zinc, and Airborne Supplement with Vitamin C per collaboration with Dr. Richard Neel.

Could you provide the suggested doses using Vitamin D3, Zinc, and Vitamin C powder? (I have been alkalizing 2-3 times a day and supplementing additional Vitamin C powder, 1 gram and ¼ tsp baking soda almost every hour in between.) I've also added Quercetin (800 mg) with Bromelain (165 mg), and Astragalus Root (400 mg), and Lugol's Iodine.

I should get my Melatonin in a day or two.

Thank you so much for a quick reply.

Mary Lou,

I did test melatonin in the sublingual form, but did not notice any difference and the report you are referring to occured around the same time that Dr. Neel reported a more difficult strain of Covid-19 in his patients that was requiring more time to see improvement and in some cases he was using even higher dosing. I suspect that report was reflecting the tougher strain that Dr. Neel had mentioned that also came with digestive issues that he previously had not seen in his covid patients. I believe this may have been the reason for the report of a delayed response in that family.

As far as dosing of zinc, vitamin D and vitamin C, unfortunately they did not state the dosing used, in the article.

One of Dr. Neel's patients in an earlier report mentioned 2,000 mg of vitamin C total per day.

The Italian study suggested a serum level of 40 to 60 ng/ml for a good response to vitamin D, but again vitamin D serum level has to be tested regularly in order to reach a specific level such as 40~60 ng/ml and the dose will vary from person to person as some people simply require higher dosing than others to reach a specific serum level. The reference range for vitamin D / 25 (OH) d serum level is 30 ng/ml ~ 100 ng/ml and would need to be tested by your doctor to get there.

Art

Art,

Thank you for your reply.

I'm on day 9 of the virus and was just able to start Melatonin the evening of Day 7. I'm glad there was no noticeable difference using sublingual Melatonin as I couldn't find any that didn't have a lot of additives.

I used the Vitamin C protocol from another page on Earth Clinic of 1000 mg every hour, with Zinc, Quercetin, and then added D two days ago. Also, few other supplements- some of which are listed in my previous post.

I had about 3 days of very bad flu-like symptoms that changed to mild sinus congestion and head cold.

Right now (day 9) I feel pretty good, (actually almost normal) except for being extremely tired and feeling very weak.

I plan on retesting the first of October and will remain in self-quarantine until then.

Can you suggest how long to continue the Vitamin C and Melatonin protocols? Today I reduced the Vitamin C to every 2 hours.

Also, I am having the best nights sleep I've had in a long, long time!

Mary Lou,

Glad to hear your sleep has improved and even gladder to hear you have fared very well with your bout of Covid!

I think what Dr. Neel is doing is waiting until you test negative and then slowly reduce your melatonin dose until you get down to around 5 mg/night.

I believe the reason he is in no rush to take his patients off of melatonin too quickly is because Covid-19 has shown damage to almost all major organs in autopsies and studies suggest that melatonin can repair much of the damage that you can't see and is not readily apparent to the patient or doctor. This damage if left unchecked may cause health issues years down the road. I think the damage has the best chance of being repaired while it is relatively fresh.

Art

Art,

Thank you for the quick replies. I hope you can offer suggestions now about a diarrhea issue that I believe is a result of the COVID.

About a week after I was released from quarantine I started having diarrhea (very liquid and sometimes explosive). It usually starts first thing in the morning and lasts for only about 1-2½ hours. Then I'd be good the rest of the day - sometimes a little drained feeling. Other than that I feel very good.

I'm thinking the diarrhea is from having COVID. I'm ending week 5 from the date I first experienced COVID symptoms. I have not been re-tested for COVID.

I tried posted EC remedies – ACV, Activated Charcoal, and Turmeric. None of these had any effect. I added Psyllium Husks and am beginning to see some slow, v-e-r-y slow, change in the firmness of the loose stools and for the most part they are no longer explosive. Diarrhea lasts about a hour now, and I've had loose stools in the afternoon for 2-3 days (which is a new occurrence)

I had reduced Melatonin to 40 mg a day and have returned to 60-80mg (depends if I can get all doses in). I take 1000 mg of Vitamin C two times a day. During the time I had symptoms, I took 1000 mg of Vitamin C 6-7 times a day.

Any suggestions on this issue would be greatly appreciated.

Hi Mary Lou,

First I would like to say thank you for coming back and updating on your use of melatonin for Covid-19 as this information is very useful for other members to help know what is useful!

Yes, I think you lessened your dose to soon. As for the diarrhea, Dr. Neel mentioned that in his more recent patients he was seeing gastrointestinal issues regularly and he felt it my be a different strain of Covid-19 than he had previously been seeing. You can try zinc at 50 mg/day for a short course to see if it is enough to regain normal digestion. Dr. Neel added antibiotics in some cases where he suspected bacterial infection.

You can also consider blackberries for the diarrhea.

If you have time, could you give us an idea of your experience with melatonin for Covid-19 and the dosing that you used throughout the treatment period? Thank you!

Art

Thank you again, Art.

I will come back and fill in my usage of Melatonin for Covid, but for this post, would you elaborate on using blackberries? For example, try 1/4 cup once a day...

I will start Zinc tonight. Do you recommend 50 mg at once or divided morning and evening, or ....?

Hi Mary Lou,

Regarding the blackberries, that seems like a reasonable dose to start with and see how you do with it. Regarding the zinc, I split my dose as the zinc is useful for sleep so I take half of the daily dose about an hour before bed with the other two supplements as I mentioned in my post about pursuit of restful sleep here:

https://www.earthclinic.com/art-solbrig-insomnia-protocol.html

Good luck and I look forward to your update!

Art

Art,

10/18/2020, Sunday.

As requested and promised, this is my post on my COVID experience and using Melatonin. I don't know that it will be sufficient evidence to support any one protocol, but maybe it will help someone.

I've tried to re-create the two weeks that I had COVID as best I can. I was not interested in documenting it at the time, but started after a few days.

My first symptoms were about 6 days after I believe I was infected. On Thursday, 9/3/2020, I had the worse sinus and head cold symptoms I'd had in my life. That was the day I was told I had been in contact with a person who tested positive.

I had been taking a COVID preventative protocol for about a week. These included Alkalizing, Vitamin C, D, Zinc, Querticin.

The next two days I felt better in the morning and worse in the evening.

By Day Four, I felt more flu like symptoms. Very severe head cold and sinus congestion, an occasional cough, and very tired. I went back to earthclinic.com for additional suggestions and the EC staff pointed me to your Melatonin posts. I ordered some.

Day 5 was very bad “flu” like symptoms. I started taking 1000mg of Vitamin C extra times during the day. The highest fever I had as 99.1.

Day 6 still the same. I started taking 1000mg Vitamin C every hour.

Day 7 I received my order of Melatonin and added 40mg that evening to my current protocol. After the first dose of 20mg at 4:00 p.m., I was so sleepy I took a 3 hour nap. After the 2^nd dose at 9 p.m., I slept till about 10 a.m. the next day. I had already started to feel a little better today.

Day 8 I added the full 80mg Melatonin today. It didn't knock me out like the two yesterday. I coughed more today than I had since this started. The worse symptom was weakness, tiredness and being shaky on my feet.

Day 9 I felt fairly good, but shaky, a little dizzy, weak, tired, and coughing a little less. I reduced Vitamin C to every 2 hours.

Day 10 I didn't feel like getting up in the morning. I was more congested. I reduced Vitamin C to every 3 hours as I was having light diarrhea and thought I was saturated with Vitamin C.

Day 11 I felt fairly good except for a little cough in the morning to clear my lungs and still tired and sleeping a lot.

Day 12 I felt fairly good today. I still had a little cough in the morning to clear my lungs. I actually walked about 2 blocks before wearing out. I was still sleeping a lot.

Day 13 I felt fairly good today too. I still had a little cough, congestion, and weakness.

Day 14 I considered myself healed at this point.

Over the next couple of days, I cut back on the melatonin.

Day 25 This was about a week and a half later and later severe diarrhea started. At first I thought it was food poisoning. When that didn't clear, I started back on my COVID treatment protocol including 80 mg of Melatonin.

At first the diarrhea only happened first thing in the morning and lasted 1-3 hours. It started severe, explosive, and liquid. I stayed on the BRAT diet and/or ate light. After (2) weeks, I ate other things and sometimes had diarrhea after lunch or dinner, but only 1-3 movements, then I was usually good.

I started back to work on 10/05/2020 feeling good except for the diarrhea.

I tried most of the popular EC remedies for diarrhea. Charcoal, Turmeric, and ACV didn't help. I added Psyllium and it helped just a little. Last week I upped Zinc to 50mg and ate ¼ cup blackberries.

I felt I needed a break from all the supplements on Friday, 10/16/2020. So Friday night and Saturday I stopped the psyllium and a lot of the supplements. Today, Sunday, 10/18/2020, the diarrhea was back full blown and for about 3 hours.

I wrote a previous post on the diarrhea only and am hoping for more help with that.

Here is my COVID protocol that I implemented over the 14 days I had symptoms:

• Alkalizing with ACV/baking soda
• Iodine 12.5 mg
• Querticin 80mg with Bromelain 165mg
• Zinc 25 mg
• Vitamin C 3000- 10,000
• Melatonin 80 mg
• Multi-vitamin
• B-Complex

I am back on the Full COVID protocol. I had some NAC so I added that too.

I will take Turmeric this week to hopefully help with the diarrhea.

I will say the Melatonin and Art's insomnia protocol has helped me sleep better than I have in years with not as many bathroom trips during the night.

Hi Mary Lou,

Thank you for the great feedback on your Covid-19 / melatonin experience!

Based on what you wrote, it appears that your Covid-19 "preventative protocol" was insufficient to actually stop or reverse the virus progression in your system as suggested by your steady system increase during those first 7 days.

My opinion of your preventative protocol is that most of those components are synergistic with melatonin and can improve the outcome of the melatonin treatment, but without melatonin they are insufficient and I feel that your experience adds confirmation to this theory.

From what I have seen so far with most things being tested for Covid-19, the sooner they are initiated, the better the outcome. Unfortunately you weren't able to actually take melatonin until a week had passed and this allowed the virus to multiply unabated that first week and the increased viral load seems to be confirmed by that continuing increase and worsening of your symptoms in that first week.

Studies of Covid-19 show that increased viral load equates to worsened symptoms and sometimes death, while lower viral loads equate to moderate to being asymptomatic and living.

On the 7th day, your first day of taking melatonin, you already had very significant symptoms and you only took a 40 mg dose of melatonin and that allowed you to get good sleep which is actually very good! Some people say that melatonin can make them feel tired the day after they take it, but it is a good thing to sleep and reach REM sleep where your body is able to do a lot of needed repair work.

Consequently, even though you only took 40 mg of melatonin the night before, you already felt a smidgen better the next morning which was a first! This is exactly what Dr. Neel has been reporting in his patients with noticeable improvement the day after the first dose. Dr. Neel recommends to other doctors to give their patients 1 mg of melatonin for every kilogram of body weight.

I don't know what you weigh, but 80 mg is probably close enough to that dosing schedule to work as Dr. Neel has been reporting in over 400 Covid-19 patients treated successfully so far.

On the 8th day, you actually took your first full 80 mg dose of melatonin that you planned to take. You noticed increased coughing and again, this can be a good indication because one of the first things that melatonin does is reduce inflammation in the lungs and with reduced inflammation and consequently reduced swelling in the lungs, the body will attempt to start clearing fluid and mucus buildup which would represent as increased coughing that should be more productive than previous coughing.

The symptoms on day 8 are to be expected.

Day 9, your second day at the full 80 mg dose again showed symptom improvement and that was to be expected.

You stated, >>> ' I felt fairly good, but shaky, a little dizzy, weak, tired, and coughing a little less. I reduced Vitamin C to every 2 hours.' <<<

Again, you are showing improvement at just your second day of full dosing!

One thing that has been shown by Dr. Neel and studies is that vitamin C has synergy with melatonin, so it may have been a bit premature to reduce the vitamin C dose, but that is unknown for certain in your case. Remember that your original preventative formula mostly has synergy with melatonin.

Day 10 you reported reducing your vitamin C dose even further after getting a little diarrhea. This is where the way the post I wrote on this subject gets a little harder to follow.

You see, whenever I got new information regarding using melatonin for Covid-19, I can not add that information to the original post, so I have to add it as a "reply" to the original post so if you don't read the whole original post "and" all of the replies to that post, you will not get all of the information needed.

In one of my replies I said that in later cases of Covid-19, Dr. Neel is seeing gastrointestinal issues that he did not see in his first 200 patients or so and he surmised that these gastro issues were likely related to a mutation of the viral strain. His solution to the problem was to add an antibiotic to try and kill whatever bacteria was causing the gastro issues, but you were probably not even aware of that update. Now if you were going to try to use some type of natural antibiotic to treat the diarrhea, it would probably be things along the line of garlic, Olive Leaf Extract, Grapefruit Seed Extract, Colloidal Silver etc.

Really just a personal choice based on what you prefer.Day 11 went fairly well with tiredness, a light cough to clear the lungs and more sleepiness which would all be expected on your third day at full dose melatonin. No mention of diarrhea.Day 12 sounds really good and again no mention of diarrhea.Day 13 sounds similar to day 12 and no mention of diarrhea.

Day 14 you said, >>> ' I considered myself healed at this point. ' <<<

On this point I would completely disagree. Your symptoms may have abated, but this in no way means that you are no longer sick! I think that many people think that if they have no symptoms, then they are no longer sick.

You are only on your 7th day of melatonin at full dose and you started a week later than you should have which essentially gave the virus a head start. Chances are you would have still tested positive at that point and to let up at that critical point is a mistake imo.

For myself in a similar situation, I would have continued with everything for at least a week more and I would probably gone even longer than that with the melatonin. Here is why. In the beginning of the original post I am talking about all of the damage that Covid-19 has shown in autopsies to many of the major organs and melatonin has shown the potential in other studies to help prevent or lessen this damage which can in time become long term or possibly life long damage.

It is my opinion, based on melatonin studies, that much of this damage can be prevented or reduced with longer use of melatonin after all symptoms have cleared. No mention of diarrhea.

From day 14, you skip to day 25 and I assume that you are relatively okay during these 11 days.By day 25 you have cut back on everything and are now trying different things to control the diarrhea.

I believe that the ACV with baking soda is a bad idea as you do not want to raise stomach pH as one of the purposes of stomach acid is to kill bacteria that enters the stomach with your food and imo can possibly be a reason for the diarrhea.

Eleven days with no symptoms suggests that you had the virus under control, but reducing stomach acid via your alkalizing method does not seem like a good idea imo.Unless I missed something, none of the things you have been taking seem to have strong antibacterial effects, except curcumin, but it is not well absorbed and would likely require a high dose, but I have no knowledge of using curcumin in this way.

The supplements I mentioned above, do have antibiotic effects as do others. Generally, but not always, diarrhea is caused by a bacteria and in your case you do not know the exact cause at this point, but if you went to a doctor, he might put you on an antibacterial regimen to try and kill any bacteria that might be causing the diarrhea.

ACV by itself might be helpful because of its low pH, but likely insufficient for full blown diarrhea and by adding baking soda to the ACV, you are significantly raising the pH of the ACV and possibly your stomach acid depending on what dose you have been using thus nullifying the possible benefit of the ACV.

Ideally, a visit to the doctor to take and test a stool sample to find out if it is a bacteria and which bacteria and knowing which bacteria would be very useful. With that knowledge he would know the best antibiotic to use. Failing that, you have a decision to make to either go to the doctor or decide if you are going to try and use naturals supplements with antibiotic effects on the diarrhea.

I am not a doctor and can not tell you what to do regarding the diarrhea.This diarrhea situation is questionable at this point whether it is related to Covid-19 or not because you went well over a week with no symptoms or diarrhea and Dr. Neel's reports only discussed earlier onset diarrhea which you did recover from, but those reports are not overwhelming with information.

It is entirely possible that this current diarrhea is unrelated to Covid-19 as even you thought that it might be food poisoning.

Art

Mary Lou,

I think that most of the residual problems that you're having after your COVID-19 infection are perhaps mainly due to the inflammation caused by existing residual virus issues(acting in the intestines) that can always occur whenever you recover from any viral infection.Don't forget that most virus have the ability to hide from the immune system(eg Herpes virus, Epstein Barr) and COVID-19 is really no different.

In all the recent research that I've read on COVID-19, it is a fact that ALL cells in the human body have special inflammation ACE-2 receptors. And since the COVID-19 virus attaches to the cellular ACE-2 receptors and disrupts it, that therefore means that ANY tissue or organ can be seriously affected by inflammation whenever you are infected by COVID-19. I've also read much research that confirms that COVID-19 inflammation can cause cytokine storms, heart mycarditis, thick blood, arterial build up and occlusion(arterial blockages), pneumonia, kidney/liver/pancreas problems as well as causing problems in the intestines.

You can perhaps use a three pronged strategy against COVID-19 by supplementing the following:

1. Serious immune boosting all-round anti-viral neutraceuticals like Ted's lysine + Vitamin C protocol or quercetin + resveratrol, or niacinamide. These are just a few of my favorites.

2. Supplement neutraceuticals that directly attack the virus by stripping the oily outer coat from lipid coated viruses(like COVID-19), which then exposes the the virus protein as a foreign protein body, which the immune system then identifies as enemy non-host protein and so it is rapidly destroyed and removed by the immune system. Neutraceuticals that can strip the oily coat of the virus are: Virgin Coconut Oil(3 tablespoons a day), simple aspirin(taken 4 times a day at 3 hour intervals outside meals) and BHT(up to 500 mgs 3 times a day outside meals).There is also alot of conflicting research evidence on BHT mainly caused by all the "spoiler research" on BHT that has been put out by Big Pharma. The best and most honest research and recommendations I've found for supplementing BHT comes from Dr Steve Fowkes, an independent and honest researcher, who has been investigating BHT's beneficial anti-viral properties for over 20 years. See his free ebook -- called The BHT Book -- for more info on BHT.

3. Take supplements that act to suppress the inflammation caused by the out of control ACE-2 receptors. Tumeric and melatonin are perhaps the best supplements to take for this -- and you are already taking them.

To further improve your residual intestinal problems(severe diarrhea) I would just do one round of Milk of Magnesia at the normal, recommended laxative dose. Make sure you do this at the weekend so you are always near a toilet. After your intestines have been cleared out by MoM also make sure that you re-mineralize the blood electrolytes by taking the appropriate minerals. MoM causes the laxative or diarrhea effect because of its high alkalinity(pH 10). At that pH MoM will also kill any pathogens(incl viruses) or parasites in your intestines. By the way, taking MoM this way is also one of Ted from Bangkok's anti-pathogen remedies for problems in the intestines.

And after you have cleared out your intestines with MoM, you should continue your current anti-COVID protocol until you are fully recovered.

Thank you Art for your input.

I'm definitely staying on the whole Covid Protocol with Melatonin for another week or two.

Bill,

Thank you for your input. I have Lysine and Vitamin C so I'd like to add that. However, I can't find Ted's lysine and Vitamin C protocol. I've spent about over 30 minutes searching posts and don't know how to find the protocol.

Can you or EC post a link?

I am taking Quercetin but not Resveratrol.

Mary Lou,

Here is a link to Ted from Bangkok's lysine anti-viral remedy. This link deals with H1N1, which is similar to the COVID-19 virus. The post also contains a list of other remedies against such viruses that also includes using Hydrogen Peroxide, MMS, Aspirin etc:

https://ted.earthclinic.com/cures/h1n1-swine-flu7.html

1 Month Update

Art and Bill,

This is my 4th week and the diarrhea was worse near the end of last week, this past weekend and the beginning of the week.

I've went back on the full Covid Protocol for 2-3 weeks and just stopped a lot of the supplements on Tuesday, 10/27

I went to the elders of my church and was anointed and prayed for according to scriptures.

I felt God directing me to look at all the supplements I was taking.

This may have gone from a Covid related diarrhea to a supplement induced diarrhea as its gotten worse over the last week.

I know that both Vitamin C and Turmeric can cause diarrhea. Also, in Art's post about Ulcerative Colitis and IBD you stated, "The 5 mg dose is a good place to start as some people cannot tolerate melatonin ".

I've already stopped Vitamin C, Turmeric, Quercetin, extra Zinc and extra D.

I'm still taking 80 mg of Melatonin, a Multi, (1) zinc, (1) D.

I added DHEA, Colloidal Silver, and (3) tbsp. of VCO this week. I added Lysine a couple of days then stopped because I didn't want to add an additional supplement until I got a better handle on what is causing the irritation.

The diarrhea is a little better since I stopped most of the supplements, not so liquid, but not formed at all and still urgent.

After the first couple of hours in the morning I'm usually good until I eat something. Then I have a very loose, urgent movement or two or three and I'm usually good till the next meal.

However, my stomach is aching almost constantly.

I'm to the point of a hard decision. I don't want damage from Covid. However, I think I've taken the protocol long enough. I can't go on with this diarrhea. I had to leave work early twice this week due to the diarrhea and/or exhaustion from it and the stomach pain.

Since, I read Art's post on Ulcerative Colitis, I'm going to stop Melatonin for the rest of today and then pick up tomorrow night with only the evening doses per Art's“restful sleep” protocol and add Zinc at night - to see if I've built up intolerance to it.

If diarrhea continues, I will stop all supplements for several days to see if any others are contributing to the issue.

I would like to resume a preventative protocol, but at this time, I want to concentrate on stopping this diarrhea.

Both your suggestions are greatly appreciated.

Hi Mary Lou.

Last time we spoke, I mentioned that you had a decision to make regarding the diarrhea, either go to the doctor or continue trying to fight it with natural substances. You have now tried the latter and the effort has not been successful. You can not continue with the diarrhea as this is preventing your body from absorbing nutrients from food you are eating, so this now leaves the doctor option so that he/she can determine the cause of the diarrhea.

In case the doctor is not able to see you immediately, you can try Pepto Bismol tablets, not the liquid, to help you last until your doctor appointment. Take as directed on the box. The doctor can take a stool sample and also test you to see if you now test negative for Covid-19. From what you have written, it sounds as though the diarrhea is your only symptom, but this is serious and needs to be stopped as soon as possible. A word of warning, the bismuth in Pepto Bismol tablets will turn your stool a blackish green color, so do not be alarmed about that.

I suggest you stop taking vitamin c, magnesium and melatonin as each one of these can cause diarrhea.

Please come back and update us on how it is going for you.

Art

Art, I think you're right about the diarrhea. Anecdotally, person in my office flies to sporting events every weekend. He is one who never covers his coughs. This past week, many of us in the office have had strange stomach pain, joint pain, fatigue and diarrhea. I'm betting we've been exposed to covid and, since we are very aware of supplements/rest/nutrition, we're fighting it off. Maybe a minor infection at this point. But how would we know without testing? And none of us want to be tested because that would shut down our department and we're essential and would have to work anyway unless seriously ill. We do not encounter the public much, so it's purely internal other than at home. And, since we're conscientious about not infecting others, I think we'll be okay. But, sucks for us to have one person bring it in.

Or the boy's ability to produce melatonin has been compromised.

Nancy11,

This is going to be a long answer.

To briefly answer your question, yes, I would lean toward "melatonin only", at least until you find that your breathing difficulty has improved significantly back toward your normal. This should help allow your lungs to heal to the extent that melatonin is capable of doing.

Once and if you improve from the melatonin supplementation, then you can consider whether you want to add H2O2 to the mix. Melatonin is likely to work against H2O2 as it is a radical and melatonin neutralizes radicals and melatonin can enter any tissues in the body and is proven to significantly affect the lungs.

More on this below and a possible workaround.This is a tough question for me, because I look at H2O2 as a very potent oxidant that can potentially lead to excess oxidative stress and I see that as the reason it would very likely be effective at destroying SARS CoV-2 that exists in the lungs via inhalation of H2O2, but once the virus is destroyed in the lungs, do you really need to keep inhaling a potent oxidant (H2O2) into COPD lungs that already have elevated levels of H2O2 as shown in existing studies?

I know there is plenty of anecdotal evidence that suggests H2O2 inhalation may be beneficial for COPD and in one sense that seems likely as it will very likely kill bacteria in the lungs that may thrive in the lungs of people with COPD and help to feed the disease process.

On the other hand, studies have shown that exhaled H2O2 is elevated in people with stable COPD compared to controls and is almost 3 times higher in COPD patients whose condition is exacerbated as opposed to stable.

This data could mean that the body is able to produce enough H2O2 for COPD lungs on its own, or it may turn out that even though the body produces more H2O2 in the lungs as the disease severity increases, it is not able to produce enough to reach maximum efficacy.

I have not seen data to confirm that additional inhalation of H2O2 will be beneficial, though the anecdotal evidence suggests it may be.

So inhaling H2O2 will add even more H2O2 to the already elevated levels in patients lungs with COPD and this is where the anecdotal evidence and the science seem to part ways as the science so far does not seem to support the inhalation of H2O2 in patients with COPD.

Oxidative stress is elevated in COPD as is inflammation and these two work together in a vicious cycle to increase each other as elevated oxidative stress increases inflammatory cytokines and mediators which also creates more oxidative stress ultimately creating an environment that is conducive to disease progression.

If you could look inside your lungs to see how they are reacting to inhaled H2O2, that would be very useful, but that is not possible and with no practical way to know if there is enough or too much H2O2 in the lungs, the melatonin may help with this aspect of H2O2 inhalation.

Melatonin, on the other hand, has many studies that show that it is beneficial for COPD patients and two of the effective mechanisms of action are its potent radical scavenging and very potent antioxidant activities as well as its inhibition of inflammatory cytokines which may have the potential to break that vicious cycle that can be quite active in COPD.

Another consideration is knowing that melatonin level drops when the disease is in an exacerbated state, exactly when more melatonin would likely be needed! Melatonin levels also decline with age.

Melatonin is the most potent antioxidant in the human body because it elevates the gene expression Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx), Glucose-6- Phosphate Dehydrogenase (G6PD) and Catalase (CAT) while increasing Glutathione. Melatonin doesn't stop there though. It is also a potent scavenger of Peroxynitrite (ONOO) which is elevated in COPD and has negative effects, it scavenges Reactive Oxygen Species (ROS) / Hydroxyl Radicals, Reactive Nitrogen Species and H2O2 which are all mostly elevated and damaging in COPD and help extend disease progression.

Melatonin is also able to do something that other antioxidants like vitamin C and E can't.

Vitamins C and E can each neutralize one oxygen radical while melatonin can neutralize as many as 10 oxygen radicals because each time it reduces one oxygen radical, melatonin becomes a different metabolite of itself and each of these metabolites can in turn neutralize another oxygen radical.

Add in the antiinflammatory qualities of melatonin and it is a potent molecule to use against Covid-19 and COPD!So given all of the above, for myself, if I wanted to try one or both of these and if I believed they both had potential to help people with COPD, I would discuss it with my doctor to see if he thought that either one or both might be helpful for me and would be compatible with my current medications. If he or she approved the use of both, then I would consider an appropriate plan of attack.

I suggest that anyone reading this also get their doctors approval before trying to implement such a regimen.

Given that melatonin is likely to work against H2O2 by neutralizing it directly or indirectly through the upregulation of Catalase or other antioxidants which will also neutralize it, I might consider a rotating approach where I use one for a day or two followed by using the other for a day a day or two. This could possibly allow the H2O2 to work while the next phase allows melatonin to give the lungs a break and neutralize the elevated radical levels in the lungs as well as lower the elevated inflammatory levels in the lungs.

H2O2 is highly likely to do some damage in the lungs and the idea being that melatonin may nullify or repair some of this damage while helping to work against COPD through its known multiple actions against COPD.

So that is my idea of how I might use these two substances under my doctor's supervision based on my experience with both substances and the available studies I was able to find. I did not include any study links in this post because it is long enough already.

Art

Dear Art,

I really appreciate this post on Melatonin, H202 and COPD. It is timely for me. We are getting ready to move my mother in law into our home and she has COPD, in addition to other health problems.

By the way, I continue to take Melatonin at night for sleep and it has definitely helped me!

Thank you!

~Mama to Many~

Hi M to M!

Thank you for saying so! I know you are probably already aware of the following, but I am putting it in for others who may not be. COPD is common, so it is worth putting this info up. Some people refer to it as emphysema, but that is an older term and COPD seems more common now as a blanket term. There are some similarities with chronic bronchitis.I'm not sure about the H2O2 for COPD simply for lack of studies to add confirmation to the anecdotal evidence, but the anecdotal evidence is compelling.

In COPD patients who are stable, the amount of H2O2 in the exhaled air is approximately 7 times that of normal controls while patients who are in an exacerbated state are almost 3 times higher than stable patients and about 21 times higher than control patients.

So H2O2 inhalation will add to these already significantly elevated H2O2 levels. This brief abstract discusses H2O2 exhalation levels in people with COPD:

https://www.atsjournals.org/doi/10.1164/ajrccm.154.3.8810624

Melatonin clearly has studies that show it benefits COPD as does NAC, which is purported to significantly reduce exacerbations at two 600 mg doses per day.

Generally elevated oxidative stress is considered to possibly be the single most important factor driving COPD disease progression, so these two seem quite useful and melatonin is the most potent antioxidant in the human body as I described in the original post. Maximum radical scavenging is desirable.HDM made it possible for me to get rid of a cough that I had had for months that was not getting better, only worse. With HDM it started to lessen in two days and was gone by the third day.Vitamin C is synergistic with melatonin and adds to both its antioxidant abilities as well as its antiinflammatory qualities.Quercetin is also useful for COPD and quercetin is also synergistic with melatonin increasing its antiinflammatory activity.

Vitamin D reduces the number of acute exacerbations also and it is almost always good to be vitamin D replete for overall health, especially with so many people being insufficient or deficient. Getting into the upper half of the reference range for 25 OH d is worth looking into at whatever vitamin D dose is needed to get there. Simply put, some people require more vitamin D to achieve a specific 25 OH d level. The 25 OH d reference range is 30 ng/ml ~ 100 ng/ml

Some essential oils such as eucalyptus are thought to be helpful with COPD also. Not everyone can tolerate melatonin. Does your mother in law have Afib?

Art

Freda,

I answered this question in the original reply I made to Nancy and there is further information re: COPD in my reply to Mama to Many.

Art

Dear Art,

Thank you for the information!

Yes, as a matter of fact, my mother in law does have A-fib!

She is actually taking a small amount of melatonin right now. She has been in a nursing home for 9 months and when her sleeping pill prescription ended, they asked if they could give her melatonin instead. Well, I was sure happy about that! I don't know how much yet.

I actually didn't realize that COPD is what they used to call emphysema. But it makes sense.

Thank you again!

~Mama to Many~

I had Covid in March and coughed almost five months without cure. I discovered that quitting all dairy immediately caused my coughing to stop! But still left with difficulty breathing, runny nose.
I found that NAC 600 mg twice a day has really helped.

Then I do a steam as I do not own a nebulizer with Theranaturals glutathione, one capsule and one drop of eucalyptus essential oil. This glutathione is made for nebulizers. Eucalyptus is beneficial for lungs.

I do not do HP.

You could try above.

Covid takes a long time to recover.

Below is a link to a nurse who had Covid-19 and Dr. Neel is her doctor. She gives an idea of what Dr. Neel is like as her doctor :

https://devinenews.com/medina-county-woman-shares-what-her-battle-with-covid-was-like/

Art

Here is a link to a new abstract that suggests that melatonin is useful for restoring the glutathione redox system as well as working against Covid-19!

https://pubmed.ncbi.nlm.nih.gov/32597503/

Art

Hello, I am currently fighting COVID and am 7 months pregnant looking for relief. Am not seeming to be getting better by much. I am a single mom of 5 kids and was wondering if melatonin would be safe for pregnant women battling COVID-19? 🙏 I can't take care of them right now and am desperate.

You might contact a church in your area, tell them your predicament, and ask if they can help. They may be able to send someone to help with childcare.

Q90FM may be able to help, too:

https://www.q90fm.com/prayer.php

🌞

Hi Jessica.

In the following 2020 article link below, it basically says that there is insufficient data to prove that melatonin is safe when pregnant and although there are tests being conducted for that purpose, that data is not yet available.

Another important point is that with Covid-19, it requires dosing that is magnitudes higher than what would be used for sleep. Bottom line is that there is no data for high dose melatonin in pregnancy, so melatonin is not a viable option for you.

https://womensmentalhealth.org/posts/update-2020-melatonin-pregnancy/

Art

But melatonin is related to the body's sleep modes ...how can that stop a virus? The body has its OWN inbuilt protocols for resisting infection and disease ... you can't ameliorate an infection using stuff that doesn't deal directly with that infection where it matters ... in the cells! In the case of virus, it's Zinc that prevents viral replication and it's Quercetin that puts it there! Now its taken that if you have LOW levels of vitamin D .... then you are a sitting duck ... and the majority of the vulnerable have that due to inability to get out in the sun coupled to a surfeit of toxic drugs courtesy of doctors making profits! HIGH Vitamin D is protective meaning that its renders infection much harder to gain a foothold ... it is NOT however a treatment once you have that virus ... that needs ultra high levels of Vitamin C ... known as LVC coupled to Zinc supplemented ... Zinc Picolinate is the best absorbed!

Someone posted that melatonin does cause next day drowsyness at first, but after you take it for a while it does not.

You can always do the usual anti-virus things--vit C and D, lysine, chicken soup, healthy diet, plenty of water, sleep, fresh air and sunshine. Melatonin surely can't hurt and may help. Whenever I am exposed to anything, even stress, I try to fall back on the tried and true remedies.

Thank you Art. I found this quote from the devinenews article you posted very helpful: “As a Ph.D. student I was taught that a virus actively kills our cells during the course of the infection…..But now I know a virus is more like a provoking bully, a bully who continues to provoke cells in our lungs and our respiratory tract to commit suicide……We analyzed the molecular mechanism, how the virus does it, and matched it with scientific databases. Then, came to conclusion that melatonin can block the process that promotes suicide in lung cells,” Shneider said. Source: https://devinenews.com/dr-neel-sees-amazing-results-in-covid-19-patients-by-boosting-amount-of-melatonin/