4 Supplements to Alleviate Long Covid

on Oct 06, 2022
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Supplements for Long COVID

It is now common knowledge that Covid-19, at least for many people, can still cause moderate to severe symptoms even after you are over the main symptoms and test negative for the SARS-CoV2 virus.

These symptoms can persist for months or even years, and some people seem unable ever to become 100% clear of these symptoms, which are typically referred to as "Long Covid."

Typical Long Covid Symptoms

  • Fatigue (Very Common)
  • Brain Fog
  • Depression
  • Headache
  • Sleep Issues / Insomnia
  • Chronic Cough
  • Lightheadedness
  • Shortness of Breath
  • Chest Pain or Tightness
  • Loss of Smell
  • Muscle Aches
  • Heart Palpitations
  • Dizziness
  • Joint Pain
  • Pins and Needles feeling in hands and or feet
  • Gastrointestinal Issues

Previously I have written about how melatonin can be useful for some of these post covid symptoms here so I won't discuss that now or count it as part of this group, but I will add that melatonin has anticoagulation effects in the blood :


Now that more research into long covid is starting to be done, we have a greater understanding of what is going on in this post-disease process and consequently an increased understanding of what supplements are more likely to be beneficial to try and counter these symptoms.

A lot of what is driving long covid is oxidative stress and inflammation which antioxidants are very useful to try and counter the increased oxidative stress, inflammation, and the symptoms related to elevated oxidative stress levels and inflammation.

This newer article (April 2022) details how Oxidative Stress and Hyper-Inflammation are major driving forces in long covid :


Here is a relevant quote from the review:

' Oxidative stress is a pivotal point in the pathophysiology of COVID-19 and presumably also in Long-COVID. Inflammation and oxidative stress are mutually reinforcing each other, thus contributing to the systemic hyper-inflammatory state and coagulopathy which are cardinal pathological mechanisms of severe stages. COVID-19 patients, like other critically ill patients e.g. with pneumonia, very often show severe deficiency of the antioxidant vitamin C. '

ALA + CoQ10

Along that line of thinking, Alpha lipoic Acid (ALA) + CoQ10 should serve well to lower oxidative stress overall in the body and the mitochondria in particular, which will go a long way in improving cell function. Melatonin is a highly potent antioxidant and radical scavenge as well as a potent anti inflammatory as outlined in the very first link.

The following new study (August 2022) gives pertinent information on why the combination of ALA and CoQ10 are likely to be useful against post Covid-19 symptoms :


Here is an important quote :

' A FSS complete response was reached in 62 (53.5%) patients in treatment group and in two (3.5%) patients in control group. A reduction in FSS core < 20% from baseline at T1 (non-response) was observed in 11 patients in the treatment group (9.5%) and in 15 patients in the control group (25.9%) (p < 0.0001). To date, this is the first study that tests the efficacy of coenzyme Q10 and alpha lipoic acid in chronic Covid syndrome. Primary and secondary outcomes were met. '

Those are good positive results in a moderate sized study group and clearly show the efficacy of the combination of ALA + CoQ10 in trying to deal with long covid. It is already established that ALA is useful for peripheral neuropathy or the pins and needles feeling in the hands and feet so I won't go into that aspect here, but those can be post covid symptoms and ALA would show its relevance there also. It is worth mentioning that the Ubiquinol form of CoQ10 is likely to be a better choice because of its superior bioavailability in adults.

In this new study (September 2022) they showed the combination of Vitamin C and L-Arginine to improve long covid symptoms via their Lincoln Survey :


Here is a relevant quote from their review :

' This survey is the first to show the beneficial effects of the combination of l-Arginine and Vitamin C in Long-COVID. Our investigation was based on a robust rationale, i.e. targeting endothelial dysfunction in Long-COVID. Indeed, endothelial cell infection with consecutive inflammatory cell recruitment and endothelial dysfunction could explain the impaired microcirculation observed across vascular beds in COVID-19, triggering vasoconstriction, ischemia, and a pro-coagulant state [92][93][94][95]. Consistent with our view, several investigators had proposed that endotheliitis could be a critical mechanism underlying systemic impaired microcirculatory function observed in different vascular beds in patients experiencing Long-COVID symptoms [92][96]. '

It is worth noting that melatonin also helps repair the endothelium through its anti-inflammatory and potent antioxidant effects.

So here we have four supplements, well 5 if you add melatonin in, that have shown benefit against many of the symptoms of long covid in these brand new studies. These are common and readily available with good safety profiles and are likely to help alleviate the symptoms of long covid and as a side benefit are likely to offer other health benefits rather than negative side effects often seen with prescription medications.

Supplements for Long-Covid

1. Alpha Lipoic Acid (ALA)

2. Co~Q10 as Ubiquinol

3. Vitamin C

4. L-Arginine

5. Melatonin :   https://www.earthclinic.com/melatonin-protocol-for-coronavirus.html

As far as dosing, it seems prudent to start with label recommendations and work upward if needed.

Many supplements are starting to show some benefit against long covid, but testing is in the very early stages as of now, but as those studies become available, I will add them. Some interesting areas of research are amino acids and synbiotic combinations.


Related Links:

25 Scientifically Proven Ways Melatonin Can Fight COVID-19
4 Supplements to Alleviate Long Covid
Coronavirus (COVID-19) Alternative Treatment and Prevention
Melatonin Protocol for COVID-19

Colloidal Silver

1 User Review
5 star (1) 

Posted by Art (California) on 10/13/2022 1452 posts
5 out of 5 stars

I was recently talking with a friend who was relating how after he got over Covid-19 in 5 days, developed a strange cough where he didn't cough much, but when he would talk, he would get spasms that made him cough and also made it impossible to continue talking. He told me he had the cough for over 2.5 months and it was getting worse instead of better, because now his voice had become hoarse and he had more phlegm that was getting darker.

I had previously given him a bottle of colloidal silver (CS) to test for another health issue, so he decided to use the leftover CS in his cold process vaporizer and inhale directly from the output port of the vaporizer for 10 minutes, three times per day for a total of 30 minutes per day. He told me he replaced the CS in the vaporizer with new CS after each use and he did this for 3 days in a row and by the third day his cough started to diminish and was gone by the 5th or 6th day, but he only used the CS for the first three days.

He was very happy with the results and said he still had some CS left over which he was going to save until needed again. I told him that I was a little surprised that he was able to recover from such a long standing cough so quickly, but I was happy to hear it! He told me that before he used the CS, he would not have been able to have this conversation with me as all of the talking would have had him coughing up a storm.


Long Covid Supplements

1 User Review
5 star (1) 

Replied by Bessie
(Camp Hill, PA)

Question: would some or all of these symptoms appear in a person who had a Covid19 vaccination? My son had the Johnson Vax about 1 1/2 years ago and has most of these symptoms for a few months lately. To my knowledge he has never had actual C-19.

1452 posts


Not all of Long Covid symptoms are also seen in people who have gotten the Covid-19 vaccine, but some are. Here is a list of 10 symptoms seen in people who have gotten the vaccine('s).

  • Pain, redness or swelling where the shot was given
  • Fever
  • Fatigue
  • Headache
  • Muscle pain
  • Chills
  • Joint pain
  • Nausea and vomiting
  • Swollen lymph nodes
  • Feeling unwell




1 User Review
5 star (1) 

Posted by ryan (dallas tx) on 10/20/2022
5 out of 5 stars

Lysine, I read on here about Lysine, on amazon you can get lysine on amazon at https://amzn.to/3TzdqlO

This worked for me, I had a dry mouth, felt tired, head was off, ached. heart would race when I would try to walk. thought I was probably going to die from long haul, had it for months

I took that lysine and within a day it took away everything. been good since. I recommend this so much.

Replied by Looms

I've wondered about this too as I used to have herpes which is a virus, and lysine helped quite a bit. Thanks for the reminder! 👍🏽😇

Replied by Jolyne

That is a wonderful testimony, thank you for sharing. I was wondering how much you took. I was using one a day but I'm thinking maybe I should take more.

Mary Wade
(Austin, tx)

My chiropractor suggested 500mg, 1 in am, 1 in pm. He did it for shingles which I had long term, not for Covid, but it is good for any virus I understand. A year later I still take it, only 500 mg in AM.


1 User Review
5 star (1) 

Posted by Blue Star (Tennessee) on 10/06/2022
5 out of 5 stars

Maca for Long-Covid Memory Issues and Cognitive Impairment

After having Covid, I soon realized I had Long-Covid. Scary-bad Alzheimer's-level memory issues. It was deeply concerning.

I started taking Maca for a multitude of issues like metabolism, depression, balancing my hormones, post-menopause, vaginal dryness, energy, etc...

After a month of supplementing with Maca, I noticed my memory and cognitive issues had greatly improved. Further research shows that Maca is also specifically indicated for cognitive function. My full memory function has returned.

Maca is know as the South American GinSeng, generally from Peru. It grows at the highest altitudes. Maca affects the pineal and pituitary glands. These glands regulate our hormones, metabolism, etc. It is an adaptogen, meaning it helps to manage stress.

Any fertility and libido issues it will balance, so be careful! I have knowledge of women with fertility issues becoming pregnant shortly after supplementing with Maca. Post-menopause women and male fertility issues are deeply supported by this herb.

There are different types of Maca. Red, black and Yellow.They are emphasized for different issues. I found an organic supplement on xoxo that combined all 3.

There are different high-potency Maca's on xoxo. You have to find and work with one that is comfortable for you. Too high potency can make you feel jittery.

I generally took about 3 at breakfast and lunch. You don't want to take it too late as it can keep you up at night ... for great sex ;)

Replied by Sue
(Southwest Virginia)

My maca root powder says that 1/4 teaspoon is a serving. Will the amount you took not have any negative impact on the body? Was that 3 teaspoons or tablespoons? I am curious. I have experienced tingling in my left foot and hands and that may have come on after Covid, come to think of it. Also recently diagnosed with hypothyroidism and that is a symptom of that as well. All this health stuff is complicated. I'd like to know what to do for that so I won't have to take thyroid meds. Went on for a while and then quit. Hoping to heal with a good diet and the Dr. Brownstein protocol.

Blue Star

Maca is indicated for Thyroid. I would go slowly with dosage as some folks have had side effects. Maca, since it helps to regulate the pineal and pituitary glands, is great for balancing our entire being. I took 3 capsules. I wouldn't over do it as it can make you jittery. I avoid taking after lunch, as it may keep you up at night.

Replied by Leah

Is xoxo the brand name of the maca with the 3 types?

Supplements for Long Covid

1 User Review
5 star (1) 

Posted by Art (California) on 11/18/2022 1452 posts
5 out of 5 stars

As I mentioned when I wrote this article about how to treat Long Covid (LC), I would add newer studies adding further information on combating LC as they become available. In that line of thinking, one of the most common Covid-19 and LC symptoms is Anosmia or the loss of smell. In this new study (Nov, 2022), it is shown that the common citrus fruit derived supplement, Hesperidin, reduced Covid-19 and LC symptoms, including anosmia :


Here is a relevant quote from the study :

' During the third wave of the COVID-19 pandemic, only 30% of initially symptomatic nonhospitalized and nonvaccinated subjects were asymptomatic about 18 days after symptom onset. Anosmia affected 50% of subjects and was the most frequently persisting symptom in 30%. Hesperidin therapy is safe and may help reduce a composite of selected COVID-19 symptoms, including fever, cough, shortness of breath, and anosmia. Further trials with this agent are encouraged. This research has previously been published as a preprint [28]. '