Have her doctor check her B12 level. B12 deficiency can cause paranoia and other psychiatric issues. If she is deficient in B12 make sure they start her on a series of B12 shots, not pills. If she eats normally and is still deficient in B12 she may have an absorption problem and in that case she will need monthly shots for the rest of her life. Take it from me, before I started receiving shots I was terribly anxious and depressed.