Recent Posts

Aortic Calcification Question for Art

56 minutes ago
Posted by Pat C (Denton TX) on 08/04/2026

Art, do you have any idea how to eliminate calcification of the Aorta. Seems to be calcium deposits. I think 10,800 fu Nattokinese - what else??
Thank you for any input.

Confused About Borax Dosing

57 minutes ago
Posted by Garynils (Pinckney, Michigan) on 08/04/2026

I'm a bit confused about dosing with Borax and would like someone to explain where I'm going wrong.

I've ordered a pharmaceutical grade Borax from " PERSCRIBED FOR LIFE." The package lists a serving size of 1/16 of a teaspoon consisting of 250 mg Borax containing 27 mg of Boron.

Using "Ted's" protocol for men of 1/4 teaspoon in a litre of water sipped throughout the day would deliver 1000 mg borax containing 108 mg of boron per day.

The " Walter Last" style stock solution on the other hand, lists 1 teaspoon of Borax dissolved in 1 quart of water with 1-2 teaspoons/day. One teaspoon = 4000 mg of Borax and 432 mg of boron. One quart of water contains 192 teaspoons. 192 teaspoons ÷ 432 mg of boron = 2.25 mg of boron / teaspoon. 2 × 2.25 = 4.5 mg/ day.

So Ted's protocol delivers 108 mg of boron/ day and Walter Last only 4.5! How are these 2 protocols comparable?

Further research on a substack called "CURIOUS OUTLIER" states that the human equivalent dose derived from animal studies on boron is 0.81 mg/ kg. I weigh 97.5 kg which comes out to 78.975 mg of boron per day. Please, is my arithmetic and reasoning correct?

  Re: Activated Charcoal for Tooth or Gum Pain

59 minutes ago
Posted by Pam E. (South West California) on 08/04/2026
★★★★★

When my cats or I have an abscess, we ingest Activated Charcoal with plenty of water, even with our food. Because, although many think it might absorb some important nutrition, a study was done that shows just the opposite is true.. .

"Digestion & Metablism Indices of Sheep When Using Activated Charcoal Supplement"

https://thescipub.com/pdf/ojbsci.2017.121.127.pdf

(Online Journal of Biological Sciences)

ALSO, people who take it 3 times a day for odor control (those who must wear a bag for fecal contents due to having had their bowel removed) do so for many years without any reports of nutritional deficiencies.

Even animals in the wild have been observed seeking out sources of regular charcoal to eat & benefit from!

  Re: Tips for Accurate Blood Pressure Readings

1 hour ago
Posted by Suzanne (Abbotsford, BC) on 08/04/2026

Being cold also makes your blood pressure higher.

  Re: Parasite Testing Methods

1 hour ago
Posted by Cynthia (U.S) on 08/04/2026
★★★★★

She was assuming you were psychotic, stating you saw worms etc? Since that episode what did you eventually do for help with these parasites?

Castor Oil, Frankincense Oil Helping ACL Ganglion Cyst

1 hour ago
Posted by Brenda (Orlando, FL) on 08/04/2026
★★★★★

I have* a ganglion cyst in my ACL and I'm scheduled for surgery this fall to remove and reconstruct my ACL. A month ago, I started applying castor oil and frankincense 1x2 daily. I also am using DMSO and a red light, but not as consistent or frequent. Today, I'm also back to my full range of motion. I called to inquire about canceling surgery this morning. Thanking the Lord for guiding me into truth and for healing.

  Borax Questions

1 hour ago
Posted by DP (PA, USA) on 08/04/2026

I have a family member that has osteoarthritis, and takes a lot of meds for other issues. Is Borax safe to take with medications? I'm also interested in it but I was wondering if I could add tart cherry (gout) to the borax and 2 liters of water or would one cancel out the other? Thanks in advance for anyone that can help.

  Re: Positive Health Loop (PHL) for Alzheimer's

1 hour ago
Posted by ariley (USA) on 08/04/2026

Dear Art,

Alzheimer's is a personnel issue for me. My father is sitting in an Alzheimer's Ward in a Nursing Home. He is 94 and every time I visit him he wants to die because he does not have his freedom. He is lost, confuse, afraid amoung many other issues. He did not want to help himself before and nothing can help him now, because of his living situation I am thankful for your post and giving me a better understanding of PHL. I just want to make sure people have more information than they need because if you have been around a person with Alzheimer's, they are not the same person as before.

Thanks again for all you do!

  Re: Positive Health Loop (PHL) for Alzheimer's

8 hours ago
Posted by Art (California) on 08/04/2026

Hi again, ariley,

Another important aspect of the PHL is that every component either directly or indirectly has a positive impact on the gut microbiome. I didn't go into the details of this in my original post as I was trying to keep it simple and to the point, but here is a comprehensive breakdown of how each component contributes toward a healthy gut microbiome and reinforces each other toward this end.

Exercise Increases microbial diversity; increases butyrate-producing bacteria; improves gut motility; reduces intestinal inflammation; increases SCFA production.
Melatonin Protects the intestinal lining; reduces gut inflammation; strengthens tight junctions (reduces "leaky gut"); regulates circadian rhythms of gut microbes; reduces oxidative stress within the intestine.
Vitamin D Activates VDR in intestinal cells; promotes antimicrobial peptides; improves barrier integrity; increases microbial diversity; helps suppress pathogenic bacteria.
Magnesium Supports normal bowel function; influences bacterial metabolism; reduces intestinal inflammation; helps maintain mucosal integrity; assists vitamin D activation.
Inulin/FOS Directly feeds beneficial bacteria (especially Bifidobacterium); increases butyrate, acetate, and propionate; increases microbial diversity; lowers colonic pH, discouraging pathogens.
Astaxanthin Reduces intestinal oxidative stress; decreases inflammatory signaling; increases beneficial species in animal and some human studies; helps preserve gut barrier integrity.
Ubiquinol Supports mitochondrial energy production in intestinal epithelial cells; reduces oxidative stress; may improve barrier repair; indirectly favors a healthier microbial environment.
NR/NMN Raises NAD⁺ in intestinal cells; improves epithelial repair; supports mitochondrial function; may reduce inflammatory signaling that disrupts microbial balance.
Lithium orotate May reduce intestinal inflammation through inhibition of GSK-3β; may improve epithelial survival and regeneration; emerging evidence suggests it can influence microbial composition through immune and inflammatory pathways. Human data remain limited.

Together they create several reinforcing loops

Rather than nine independent interventions, they work together. This is why I named it the Positive Health Loop or PHL. These positive health loops can work against the negative health loops that develop with aging and certain disease states.

1. Healthier intestinal barrier

Several components strengthen the intestinal wall:

  • melatonin
  • vitamin D
  • magnesium
  • NR/NMN
  • ubiquinol
  • astaxanthin
  • lithium

A stronger barrier:

  • keeps bacteria where they belong
  • reduces endotoxin (LPS) leakage seen in leaky gut
  • decreases systemic inflammation
  • creates a more stable habitat for beneficial microbes

2. Increased SCFA production

Exercise and inulin/FOS work especially well together.

Exercise encourages growth of butyrate-producing bacteria while inulin supplies them with fermentable fiber.

The result is increased production of:

  • butyrate
  • acetate
  • propionate

These SCFAs then:

  • nourish colon cells
  • reduce inflammation
  • strengthen tight junctions
  • support regulatory T cells
  • promote microbial diversity

3. Reduced oxidative stress

High oxidative stress tends to favor less desirable microbes.

PHL lowers oxidative stress through:

  • melatonin
  • astaxanthin
  • ubiquinol
  • NR/NMN
  • exercise
  • vitamin D

A lower-oxidative environment generally favors a more balanced microbiome.


4. Reduced intestinal inflammation

Almost every component lowers inflammatory signaling through different pathways.

Examples include reducing:

  • NF-κB activation
  • inflammasome activity
  • inflammatory cytokines
  • reactive oxygen species

A less inflamed intestine is generally associated with greater microbial diversity and more stable beneficial communities.


5. Improved mitochondrial function

The gut lining is one of the body's highest-energy tissues.

Energy support comes from:

  • ubiquinol
  • NR/NMN
  • melatonin
  • magnesium
  • exercise
  • butyrate (from inulin)

Healthier intestinal cells create a healthier environment for the microbiome.


6. Better circadian regulation

Gut bacteria have daily rhythms.

Melatonin:

  • synchronizes intestinal clocks
  • improves nighttime gut repair
  • influences microbial rhythmicity

Exercise also reinforces circadian biology, helping maintain healthy microbial oscillations.


7. Improved immune regulation

The intestine contains roughly 70% of the body's immune tissue.

PHL components help normalize immune function:

  • vitamin D
  • melatonin
  • SCFAs
  • exercise
  • lithium (through GSK-3β inhibition and downstream immune effects)
  • astaxanthin

This reduces excessive immune attacks on beneficial bacteria while preserving defenses against pathogens.


8. Greater microbial diversity

Several components have been associated with increased diversity, including:

  • exercise
  • vitamin D
  • inulin/FOS
  • astaxanthin

Higher diversity is generally associated with greater resilience of the gut ecosystem.

A systems view

One way to think about the PHL is as supporting the gut ecosystem from multiple angles simultaneously:

Exercise ↓ Better diversity ↓ Inulin → More SCFAs ↓ Healthier colon cells ↓ Less inflammation ↓ Better barrier integrity ↓ Healthier microbiome ↓ Lower systemic inflammation ↓ Healthier brain ↓ Better autonomic regulation ↓ Better gut function

Melatonin, vitamin D, magnesium, ubiquinol, NR/NMN, astaxanthin, and lithium reinforce this cycle by improving mitochondrial function, reducing oxidative stress, supporting epithelial repair, and modulating immune responses.

Relative importance

If I were to rank the components by their direct influence on the gut microbiome itself (as opposed to their indirect systemic effects), I would estimate:

  1. Inulin/FOS (SCFA support) — Direct prebiotic effect; the strongest driver of beneficial microbial fermentation.
  2. Exercise — Robust evidence for improving diversity and butyrate-producing bacteria.
  3. Melatonin — Strong support for barrier protection, circadian regulation, and anti-inflammatory effects in the gut.
  4. Vitamin D — Important regulator of intestinal immunity and barrier function via the vitamin D receptor.
  5. Magnesium — Supports bowel function, epithelial health, and indirectly shapes the microbial environment.
  6. Astaxanthin — Promising evidence for reducing intestinal oxidative stress and supporting beneficial microbial shifts.
  7. NR/NMN — Likely beneficial through improved epithelial energy metabolism and repair; direct microbiome data are still emerging.
  8. Ubiquinol — Primarily benefits the host's intestinal cells rather than directly altering microbes, but this may indirectly support a healthier ecosystem.
  9. Lithium orotate — Plausible indirect benefits through reduced inflammation and GSK-3β inhibition, but current evidence for direct microbiome effects is the least developed of the group.

Overall, the PHL's effect on the gut microbiome is unlikely to arise from any single component. Its strength is that it simultaneously provides prebiotic fuel, strengthens the intestinal barrier, enhances mitochondrial function, lowers oxidative stress and inflammation, regulates immune and circadian function, and supports epithelial repair. These mechanisms reinforce one another, making the whole regimen potentially more effective than the sum of its individual parts. For Alzheimer's disease specifically, adding low-dose lithium may further complement these effects by promoting a less inflammatory intestinal environment, although that aspect remains an area of active research rather than an established clinical benefit.

Art

  Re: Borax for Psoriasis Flaking

12 hours ago
Posted by dee (Concord, NH) on 08/04/2026

By "one full mix" I assume you mean drink the whole 32 ounces throughout a day, correct?

 Re: Back Muscle Spasms That Move - Muscle Virus?

13 hours ago
Posted by ariley (USA) on 08/04/2026

Dear Servant,

The best answer I could find on moving muscle spasms is in Chinese Medicine. Your Liver could be causing issue or Blood nutritional aspects. TCM has seasons that change and so can health. Read this over to see if other symptoms apply to your situation.

Wind conditions during late summer may manifest as:

  • Physical Symptoms: Dizziness, headaches, and muscle spasms.

https://www.meandqi.com/knowledge-base/conditions/muscle-spasm

  Re: Positive Health Loop (PHL) for Alzheimer's

13 hours ago
Posted by ariley (USA) on 08/03/2026

Dear Art,

I wanted to expand on to your gut health.

Importance of Gut health!

Probiotics can improve spatial memory, reduce hippocampal plaques, and restore synaptic plasticity in AD models. Gut microbiota functions as a dynamic endocrine system that produces bioactive metabolites, such as GABA, serotonin, and dopamine, essential for regulating mood and supporting cognitive function.

One study showed in autopsy of individuals with Alzheimer's that Lactobacillus was low and Bifidobacterium high.

Short-chain fatty acids (SCFAs) like butyrate and propionate, produced in the gut, can reduce brain inflammation by strengthening the blood-brain barrier and inhibiting inflammatory pathways in brain immune cells. They also enhance the production of regulatory immune cells that help control neuroinflammation.

Alterations in gut microbiota can lead to increased production of cytokines, which may contribute to neuroinflammation and conditions like Alzheimer's and Parkinson's diseases.

https://pmc.ncbi.nlm.nih.gov/articles/PMC12999160/

https://www.nature.com/articles/s44400-025-00048-6

Lactobacillus Eats Amyloid Plaque

https://www.mdpi.com/2076-3921/13/10/1225

This is a reason I promote using a Leaky Gut Protocol even if you don't have Leaky Gut. You kill off parasites, bacteria, candida etc. Heal the gut and reestablish good bacteria. This aids in many health issues.

  Re: Treatment for Ear Mites - Update

13 hours ago
Posted by Julie F. (Winter Park, Fl) on 08/03/2026

Frontline is completely ineffective for fleas and it has been that way for years. It makes me so angry to see it at Walmart because it does not work for fleas! Please don't waste your money.

  Re: Fenugreek Water + for Appendicitis

14 hours ago
Posted by Rob (atlanta) on 08/04/2026

Hi Christine,

May I ask which brand of magnesium oxide powder did you use and in how much water did you mix it exactly?

16 oz (500ml)? 8 oz (250ml)? as the water tap, well, distilled, reverse osmosis, spring?

Did you drink this right before sleep?

Thank you

  Re: Parasite Testing Methods

14 hours ago
Posted by Sharon (Fallon, NV) on 08/04/2026

I had the same experience with my doctor. However, by the time I received negative results, I was already using a parasite detox and passing worms and eggs. I have since learned that parasites are active during a full moon and that's the best time to test. A veterinarian is your best bet for testing. Other than that, there are only two labs worthy of testing your feces for worms. One lab is in Texas and the other is in Mexico, where in some regions they are required to detox parasites. My doctor admitted she knew nothing on the subject of parasites, as it's not taught in medical school. She asked me too keep her posted. I spoke to her assistant about my findings. One week later I got a call back, asking me to come in for another test. No need for a stool specimen. This test would be performed by a Psychologist. I was told that I could be experiencing a type of psychosis. I agreed to come and bring my two daughters and my grandchildren for testing. Those that saw the worms and eggs. She back peddled, shocked that someone else beside myself had seen the little worms. I haven't been back to see my doctor since. I've had worms exit my nose, ears, anus, and skin.

  Re: Positive Health Loop (PHL) for Alzheimer's - Art New Article

23 hours ago
Posted by Art (California) on 08/03/2026
★★★★★

Thank you very much for saying so, ariley!

I'm glad you brought estrogen and testosterone up. If you check with AI, I think you will find that the PHL will tend to have a normalizing effect on estrogen and testosterone levels. Here is a little AI snippet on that topic :

Based on what we know about the biology of the components of the PHL, it is plausible that the PHL could help maintain or normalize sex hormone signaling in aging, but it is unlikely to substantially increase estrogen or testosterone levels directly. In the context of Alzheimer's disease (AD), that distinction is important because preserving hormone function and receptor responsiveness may matter as much as increasing hormone concentrations.

Art

 

  Positive Health Loop (PHL) for Alzheimer's - Art New Article

1 day ago
Posted by ariley (USA) on 08/03/2026

Dear Art,

Great Post!

https://neurolaunch.com/estrogen-effects-on-male-brain/

Men produce estrogen continuously through an enzyme called aromatase, which converts testosterone into estradiol right inside brain tissue. That locally produced estrogen shapes memory formation, protects neurons from degeneration, regulates mood, and keeps cognitive function intact across a man's entire lifespan.

----

The more fat a male, especially belly fat, more estrogen is produced leading to lower testosterone levels.

Long-term health risks associated with estrogen dominance in older men include infertility, erectile dysfunction, gynecomastia, and an increased risk of conditions such as dementia, depression, cancer, diabetes, and blood clots.

--------

Oestrogen levels and dementia risk in senior women

Oestrogen plays a role in memory-related brain areas, and its levels drop significantly after menopause, which may increase dementia risk. Some studies suggest hormone replacement therapy timing around menopause could influence this risk.

Benefits of Bio-Identical hormones are beneficial in memory and mood.

Wanted to show the importance of Estrogen and Testosterone in men and women. A what is considered a Female Herb can aide men in Estrogen dominance. It lowers prolactin levels to balance hormones.

  Re: Where to Buy Borax?

1 day ago
Posted by Rob (Kentucky) on 08/03/2026

Dollar General Store... 20 Mules Laundry Detergent = Borax

Positive Health Loop (PHL) for Alzheimer's - Art New Article

1 day ago
Posted by Earth Clinic on 08/03/2026
★★★★★

Don't miss Art's latest article on the PHL for Alzheimer's!

https://www.earthclinic.com/cures/alzheimers-positive-health-loop-phl.html

  Re: Trying to Locate Carditone in the UK

1 day ago
Posted by Veronica (London uk) on 08/03/2026

Thanks Art


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