Methylene Blue Cures

| Modified on Aug 25, 2021
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Considered both a medicine and a dye, methylene blue has a variety of medicinal applications. The first synthetic drug created, methylene blue originally served as an effective malaria treatment. While still used as a malaria treatment today, the applications now extend far beyond this singular use to include a wide array of purposes.

What is Methylene Blue?

Known as a heterocyclic aromatic chemical compound, methylene blue possesses a unique molecular formula that situates it well as an effective medicinal treatment. The compound appears as a solid, odorless, dark green powder when held at room temperature. However, when mixed with water, the green powder dissolves and yields a characteristic blue solution.

With this characteristic color, the compound is often used in medicinal practices to perform medical tests and surgeries as it colors the bodily fluids and tissues, making them easy to see.

Methylene blues is also considered a form of hemoglobin. Hemoglobin is a substance that transports oxygen and distributes it to the tissues and organs. As methylene blue functions in much the same way as hemoglobin, it is effective for treating a wide range of conditions.

Health Benefits of Methylene Blue

Used as both a dye and a medicinal treatment, methylene blue possesses a wide range of effective applications. The compound is considered a mild antiseptic, so it can be used to kill bacteria in the body, particularly in conjunction with other treatments. These and other properties make it an effective treatment for a variety of other conditions as well.

Methylene blue is often used as a treatment for urinary tract infections and other mild infections in conjunction with other treatments. Additionally, the compound can be used to treat malaria, cancer, skin conditions including psoriasis, Alzheimer’s disease, and cyanide as well as carbon monoxide poisoning. It is also used as a treatment for parasites, swine flu, and Parkinson’s disease.

While several applications for the treatment have already been identified, it is likely that continued research will reveal more applications for methylene blue. In any case, care must be taken when using the treatment to prevent interactions and adverse effects associated with overconsumption.

Anxiety, Panic Attacks, Intestinal Cysts

1 User Review
5 star (1) 

Posted by Bennie (San Diego, California) on 05/18/2013
5 out of 5 stars

UPDATE; Four months of Methylene Blue.

It has no effect on chronic fatigue - doesn't give me any energy; also doesn't keep me up at night if I take it right before bed.

There are two areas where it seems to have worked magic: Cysts and Anxiety; as well as other benefits for insomnia and problem solving.

It did clear up my long term liver/kidney/diaphram/intestinal cysts, and for that, I am very grateful. I stopped taking it for about a week, and the pain radiating from what used to be the most painful cyst began to return, so I am sure this is what fixed them, although I have no idea why it came back and whether to continue taking MB indefinitely.

Anxiety: There's something about MB that fixes my generalized anxiety. It's fairly miraculous in that regard. I did not take it for anxiety, but I notice an improvement (almost total resolution) when I take it. As a result, don't need xanax. Again not sure whether it is safe to take indefinitely for anxiety.

Along with the reduced anxiety, it helps me to focus more on problem solving. Not a complete resolution but a definite improvement. I have chronic fatigue related brain fog, and it definitely gives a boost in that department so I can see why it is being used successfully in Alzheimer's patients.

I think I am sleeping better -- deeper sleep, not getting up so much in the middle of the night, because of the MB, which is huge because I've lived through 25 years of insomnia. Used to take RX sleeping pills of various kinds (4-5 days per week) but not taking them anymore.

When I first started the MB in Feb 2013, I experienced significant tingling in my head (felt like brain buzzing). I was taking several milligrams of melatonin per night, and drinking coffee during the day. Both of those were a problem while taking MB but now, after a few months, I am able to drink a regular cup of coffee now and then with no adverse reactions. I also take a much lower dose (1. 5 mg) melatonin with no side effects. For some reason, tea creates no problems.

MB had no effect on yeast/candida, herpes related virus, or fungal infections.

Other than occassional "brain buzzing", I think MB may have a negative effect on vision (blurrier, esp at higher doses). It MAY have a positive effect on acne but I've been taking a skin/nail/hair formula as well and think it is because of that that my acne has improved.

I am taking 3-5 drops of 0.1% per day.

Perhaps E.C cross post this to Anxiety/panic attacks; and intestinal cysts.

EC: Bennie's latest update has been cross posted from her thread in the Q&A section on the Methylene Blue page here:

Replied by Joy
(Battleground, Wash)

So glad this is helping relieve some of your suffering. Curious about what intestinal cysts are. Did you get a medical picture of them? Love, JOY

Replied by Stanster
(Wilmington, Nc)

I had tried methylene blue for my brain fog, lack of energy and achy joints, etc. I've been told I have Fibromyalga or Chronic fatigue. I didn't get any great results.

After further study I feel I have Lyme's and overgrowth of those little critters: Borealis bacteria. I urge you to read (google) all you can about Dr. Lee Cowden's protocol. He is doing medical studies using certain herbs and detoxifiers to kill off these bacterial invaders. This is probably the root cause of your problems. This info has changed my life, hope this helps anyone suffering from strange symptoms the medical doctors can't figure out.

Replied by Lena
(New York)

5 drops? ...I am taking 40 drops of Methylene Blue and do not see much of an improvement, but I am taking it only for 3 weeks so far.


I just read somewhere that too much of MB has the opposite effect. I have also cut and pasted from a nootropics page what happens with co q 10 ...

"Methylene Blue donates electrons in the electron transport chain in your mitochondria. So experienced neurohackers suggest avoiding CoQ-10 or idebenone when using MB because it seems to make Methylene Blue much less effective."

Replied by Brass Player
(Sw Usa)

I also thought I had Lyme disease. It turned out that I had an ongoing toxic mold exposure, that nearly killed me before I found out what it was (and not from a doctor) and got out of my house that had a hidden water leak. Lyme and CIRS (toxic mold illness) have extremely similar symptoms, and common mis-diagnoses are CFS, Fibromyalgia, and any other "syndrome" disease.

Anyone whose doctor says "it must be a virus" yet it never goes away, should go read survivingmold site. Water damaged buildings are common but the vast majority of physicians are not cognizant that 24% of the population has a genetic haplotype that is susceptible to the toxins. So only 1/4 of the people in a water damaged building will be extremely ill, and the other 3/4 either not ill or only with niggling minor illnesses. Well worth a look for the CFS/Fibro people. If I hadn't found out it was mold, I'd be dead.

Benign Skin Lesions

1 User Review
5 star (1) 

Posted by Lisa (Hawaii) on 08/17/2017
5 out of 5 stars

METHYLENE BLUE, I have been using MB topically on benign skin lesions, the doctor had been freezing them off, but they eventually come back and the freezing is painful. So I just applied the 2.3% (fish stuff) directly on the spots. They take up the dye, and dry up, I reapplied it to the larger spots a few times, the small spots just healed up very fast. skin is looking great, no pain.


1 User Review
5 star (1) 

Posted by Daboo (Amherst, MA) on 02/27/2014
5 out of 5 stars

I was taking Methylene Blue (12-13 drops in 8 ounces of water) with a thousand milligrams of vitamin C for about a week & I noticed the severity of my candida related itchy skin was reduced, I then upped my dosage by a few more drops per day (14-15 drops) in about 9-10 ounces of water, and a few hours later my stool was loaded with dead candida overgrowth! I normally have bad constipation but this time my "relief" was smooth and easy I was amazed. Also, I use the Methylene blue stain directly on my skin where I have itchy candida rashes, yes it stains! But only for a few days & most of it will wash off with soap and water, so use it where it cannot be seen, and it will take you itchy rash away with relief within 10-15 minutes and the relief will last for like a week, until the bugs send out a new invading force! I have also use Methylene Blue in more diluted parts for itchy skin in more visible areas with relief & I found it is also good for tooth aches.

P.S when I take it in strong doses your urine turns blue for about a day, but when you stop taking it it turns back to normal & I take vit C 500-1000 mill and have had no problems with my eye coloring, which I also heard is reversible if you should happen to have that happen to you.

Replied by Piro

Was the cure PERMANANT?

Replied by James
(Liverpool, Uk)

Please tell me what concentration of methylene blue you were using in your drops. I'm taking 1 drop 2. 4% but getting nowhere. Ted told me 5 to ten drops 1%, similar size to mine. Likely you are taking more than me.

Replied by Katerina

Methylene Blue - how much should be taken for the optimal results. I am using Kordon brand. Thank you!

Replied by Nadine
(Union Grove, Wisconsin)
14 posts

I bought kordon. and wondering how to dilute this down seeing that it is 2.33 %. I am not good with percent as a lot of people may be.

Replied by Janet


Here is how we do it. We use that brand. The bottle should have powder in it. I fill the bottle to below the rim with spring or distilled water cap it and shake. Do this on a paper or glass plate it stains. Citrus cleaner or lemon removes stains. In a two oz. Dropper bottle I add 4 stoppers of the concentrate then I add water to that carefully it loves to overflow leave room to put dropper back in. It makes .01 % solution. Then you can use whatever your remedy calls for. Do not forget to add c with it when you take it. Janet


1 User Review
5 star (1) 

Posted by Susanna (Skagit, Wa) on 12/22/2017
5 out of 5 stars

Research indicates Vitamin C may inhibit Methylene Blue's killing of Candida

Ted's advice on many areas of health have been of great assistance to me. I became interested in trying Methylene Blue for attacking my systemic Candida, and did some additional research. I came across a study that indicates that taking Vitamin C with MB may decrease the effectiveness of its impact on Candida. The research is found at

The relevant quote is halfway through the abstract: "... sensitivity of Candida cells to MB could be rescued upon the supplementation of ascorbic acid, an antioxidant." In the context of the abstract, this "rescue" seemed to be contrary to the intent of killing Candida cells.

Therefore, I began to take MB 1 drop twice a day (along with BHT), but taking ascorbic acid at least two hours later. My reasoning was taking such a small dose had no risk of side effects (coloring eye, etc.), but that any potential impact on Candida would not be lessened by the ascorbic acid.

I understand that Ted is not currently up to responding, but am hopeful that this information may help others, if you or someone may take a look at it and comment on how to take MB and Vitamin C (perhaps 2 hours between the two?).

Hoping this may assist others in recovery from Candidiasis;

Sincerely, Susanna

Chronic Fatigue

1 User Review
5 star (1) 

Posted by Cynthia (California) on 09/12/2016
5 out of 5 stars

I found that methylene blue works great for chronic fatigue. It was like someone hit my on switch. My energy level and thinking improved drastically and I was easily able to give up caffeine. However, the reason why methylene blue was able to work so well for me is that my chronic fatigue was due the fact that methylene blue treats mitochondria damage, and I have mitochondria damage from taking Cipro. Never take Cipro.


1 User Review
1 star (1) 

Posted by Pat (Salem, Oregon) on 01/20/2012
1 out of 5 stars


After reading your website, I was excited to try out the methylene blue for my yeast and "brain fog". I followed instructions, taking it with powder vit c and baking soda. I took it only one time because in researching a bit more, I saw where taking Methylene blue with anti depressants can cause serious problems with the serotonin in the brain.

"Although the exact mechanism of this drug interaction is unknown, methylene blue inhibits the action of monoamine oxidase A—an enzyme responsible for breaking down serotonin in the brain. It is believed that when methylene blue is given to patients taking serotonergic psychiatric medications, high levels of serotonin can build up in the brain, causing toxicity. This is referred to as Serotonin Syndrome. " (food and drug administration webpage)

I have been on effexor for 10 years, and although I plan to go off this slowly in the summer, it looks like I will not be able to use the methylene blue as planned.

Was this on your website and I missed it? If not, you might want to add this information. I'm glad I caught it, but very disappointed I cannot benefit from taking the methylene blue. Any other suggestions?

Thank you, Pat

Replied by Randy
(Myrtle Beach, Sc)

hi Pat, Very good point you made. I know I had mentioned this in one of my previous posts. While we are on this topic... Someone also has to be careful taking Resveratrol and/or Curcumin along with any antidepressant because Resv and Curcumin also have some MAOI properties. Just a heads up.

Replied by Wat
(Digby, Nova Scotia)
8 posts

more likely mis-information and half truths from FDA and Big Pharma research studies... In any event once your clean of their poisons you should have no further excuses NO! So use it then.

Cytokine Storms

Posted by Tim (Minnesota) on 01/15/2021 4 posts

The only drug known to inhibit the excessive production of reactive species and cytokines is methylene blue, a low-cost dye with antiseptic properties used effectively to treat malaria, urinary tract infections, septic shock, and methaemoglobinaemia.The relatively poor efficacy of anti-cytokine drugs is explained by the fact that they act on one or a few of the dozens of cytokines involved, and because other mediators of inflammation – reactive oxygen and nitrogen species – are not targeted. When produced in excess, reactive species cause extensive cell and tissue damage.

Replied by Bill

Using Methylene Blue is not just a hypothesis.Regarding using methylene blue(MB) against COVID-19 ARDS, there is an Indian doctor, Dr Deepak Golwalkar, who, as a pulmonologist and lung specialist, has been using his nebulized/sublingual MB treatment for quite a while and with great success for his pneumonia patients and for his COVID-19 patients with ARDS. Here is his website, which details his treatment:

Interestingly, Dr Golwalkar also uses exactly the same concentration of MB for nebulizing -- 0.1% methylene blue -- which is the same concentration that Ted from Bangkok recommends.

Replied by Dame Nikki


DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis


Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various inflammatory conditions as well as for cancer. Despite its widespread use, there is a paucity of data regarding its safety and efficacy as well as its mechanism of action in human cells. Herein, we demonstrate that DMSO has ex-vivo anti-inflammatory activity using Escherichia coli- (E. coli) and herpes simplex virus-1 (HSV-1)-stimulated whole human blood. Specifically, we found that between 0.5%-2%, DMSO significantly suppressed the expression of many pro-inflammatory cytokines/chemokines and prostaglandin E2 (PGE2). However, a significant reduction in monocyte viability was also observed at 2% DMSO, suggesting a narrow window of efficacy. Anti-inflammatory concentrations of DMSO suppressed E. coli-induced ERK1/2, p38, JNK and Akt phosphorylation, suggesting DMSO acts on these signaling pathways to suppress inflammatory cytokine/chemokine production. Although DMSO induces the differentiation of B16/F10 melanoma cells in vitro, topical administration of DMSO to mice subcutaneously implanted with B16 melanoma cells was ineffective at reducing tumor growth, DMSO was also found to block mouse macrophages from polarizing to either an M1- or an M2-phenotype, which may contribute to its inability to slow tumor growth. Topical administration of DMSO, however, significantly mitigated K/BxN serum-induced arthritis in mice, and this was associated with reduced levels of pro-inflammatory cytokines in the joints and white blood cell levels in the blood. Thus, while we cannot confirm the efficacy of DMSO as an anti-cancer agent, the use of DMSO in arthritis warrants further investigation to ascertain its therapeutic potential.

Diluting Methylene Blue

Posted by Gilbert (Grand Marais, Mn) on 08/17/2017 4 posts

Methylene Blue Dosages

Reading here and elsewhere all the discussion about MB, could be helpful to put it all in perspective. I ran across also an article (link posted below) that helped with some aspects of the questions. The accepted doses for various conditions cover a range of three orders of magnitude, ~ 50 mg to as little as 50 micrograms. Even if a person determined the dilution necessary for the final dose it might not be the best amount for that person. Genetics, epigenetics and the mediation of microbiomes on any medication does make fools of MDs who are inflexible. How to get a particular dose? I have several droppers from herbal extract 1 oz bottles. One is graduated in 1/4 ml increments.

So, one ml, close 2/3 of that dropper, of the fish tank solution of 2.3% methylene blue is gonna be about 23 mg methylene blue. Just now tried with water and found 8 drops ~ .25 ml. 1 ml water is 1 gram. With MB drops the equivalent could be different because of surface tension and viscosity but that I will try later. Rough estimate at the moment is 1 drop/30 mg of 2.3% MB solution contains ~0.7 mg MB. If you want a dose in that range put n drops into a glass of water.

Replied by Nathan Corbett Md

Please don't take any grade other than pharmaceutical! Methylene blue can be contaminated with heavy metals or other contaminants if it is prepared without human consumption in mind. If you go to a local compounding pharmacy (in NS the medicine shoppe is one I've had reasonable success with) they can help you out. At the pharmacy, you do not want the ophthalmic solution, as it is not tested safe for consumption either. They may be confused and initially ask you for a prescription from a doctor, but you do not need one. Methylene blue is a bulk chemical, not a drug, and as such you are left on your own in finding the appropriate grade to consume that will not hurt you over time.

Diluting Methylene Blue
Posted by Genie (Ne Ohio, Usa) on 03/16/2017 5 posts

Greetings. I'm on the candida protocols from book. I had to buy 1% MB, rather than the 0.1% called for. I thought I had figured out how to dilute but also confirmed where Bill addressed the problem for another person.

I followed as he states: 1 part by volume of 1% to 9 parts water. I used tablespoons, 1 to 9. Then I thought I understood that would be my jar supply to work out of. I then did 10 drops (protocol amount) from that new mix and added water for drinking. Added 1/4 tsp sodium ascorbate as directed whereupon he says it should go from blue to clear. It did not clear. I'm guessing maybe he expected my powder to be same strength as his powder...or something like that? My powder is 'crystalline' and states 1/4 teaspoon is 1112 mg vitamin C as sodium ascorbate and sodium 137 mg. I guess I thought powders would be one basic same 'strength'. I added another 2 teaspoons once before hoping that would help but it did not.

I could certainly be 'one sandwich short of a picnic' in my reasoning so please help me get un-stumped. I'm very new at this stuff as well as having 50 varieties of foggy, soggy brain. Thank you for sharing your power around the universe.

Goofy Genie

Replied by Bea
(Brisbane, Australia)

I haven't read the instructions, but I am very familiar with vitamin C. Usually vitamin C means Ascorbic Acid. Sodium ascorbate is also called vitamin C - as are all the ascorbates, but the ascorbic acid has been reacted with in this case Sodium and is fully buffered so a neutral pH. This will react different chemically to straight ascorbic acid. In the instructions did they mention which form to use?

Diluting Methylene Blue
Posted by Sandcastle (Mesa, Arizona, Usa) on 07/23/2013

I cannot find the dilution formula for the 2.3% 4 ounce bottle on this website. Wouldn't I get a. 1% dilution if I simply add 22 more 4 ounce bottles of water to the original in a larger container to give me . 1% dilution? Sorry I sent a previous email without mentioning that this is a 2.3% solution of methylene blue.

Replied by Chris

MB Dilution: To arrive from a 2.3% solution to a 0.1% solution you simply add 23 units (drops, oz, etc) of distilled water for every 1 unit of MB. I used a glass eye dropper container. Add 20 drops of 2.3% MB, then add 460 drops of distilled water.

Diluting Methylene Blue
Posted by Meera (Toronto, On, Canada) on 07/06/2011

Could someone please provide a single, lucid description of how to dilute and consume Methylene Blue? The concentration of the stuff sold at pet stores is "1, 943mg per 100ml. " How should this standard, bought solution be diluted, according to metric and Imperial systems of measurement? Measurements using cubic centimetres and the like are not much good to those of us without chemistry labs. ) Thanks.

Replied by David
(Vicksburg, Ms, Usa)

1 cubic centimeter = 1 mL

1 mL = 1 g

The above are temperature dependent but work well for normal laboratory or home use. The concentration of your stock solution is 19,430 mg/L. MB solubility is approx. 1 g per 25 mL of water, 65 mL of alcohol.

At maximum solubility the concentration is 40,000 mg/L so your stock solution is a little less than 50% by volume.

Dilutions can be calculated by ratio and proportion using this formula


where M1 is the mass or concentration of stock solution. M2 is the mass or concentration of target solution. V1 is the volume of stock solution required to make target solution.

V2 is the volume you want of the target solution. for example to make 100 mL of a 0. 1% solution

50*V1 = 0.1* 100 so

V1 = 10/50

V1 = 0. 2 mL or 0. 2 grams of the stock solution

I hope this help you understand how dilutions work. I do not know what concentrations you should injest. My example is just to show you how do make the dilutions.

Replied by Flora
(Calgary, Alberta, Canada)

hi Meera ; you can purchase MB at Script pharmacy in Calgary Alberta. I am sure you have compounding pharmacys in TO. Script made mine to the concentrarion I asked for! This should make it easier for you. Hope that helps. Flora

Replied by Bob
(San Francisco)

I use two drops in a shot glass of distilled or spring water.

Replied by J. Park
(Cerritos, Ca)

I know it's way late, I guess you already have answer, but I see so many confusions about % of solution, so here it is for those still confused:

% = g/cc, what you have 1.943g/100cc = 0.019 =~ 2% solution.

To make 0.1%, add 19 x water to it.

But better way of using it is use what Bill said:

. just use 1 drop and consider it to be 20 drops of standard 0.1%.

. add 20oz water to it. Now your 20oz is equiv. to 20 drops.

. If you take 1 oz, you just took 1 drop,

take 2 oz, you just took 2 drops, etc...

Good luck.

Diluting Methylene Blue
Posted by Randa (Ontario, Canada) on 05/07/2011

I have purchased methylene blue from a pet store, it says the concentration is 1,943mg per 100ml... What concentration would that equal to?

Diluting Methylene Blue
Posted by V Kiong (Kuala Lumpur/kg Cham, Ft/kg Cham, Malaysia/cambodi) on 04/17/2011

I bought a bottle of Interpet Methylene Blue No. 10. However, nowhere was it stated the concentration. I ask the importer but they do not know. I have tried to call the company but so far have not been successful. Does anyone out there know its concentration? Thank you.

V Qiong, Kampong Cham, Cambodia

Replied by Randy
(Jersey City, Nj, Usa)

be careful with this stuff. the way I've used it is to take one drop into a gallon of water, then dilute a bit further every time I take it by filling a cup or water bottle with 1/2 or 2/3 of the MB mixture and the rest with just water. don't forget to take with 1000mg vit c

Diluting Methylene Blue
Posted by Terri (Fort Myers, Florida) on 11/30/2010

I purchased a 2.303% methylene blue solution from local pet store. Instead of going through dilutions, can anyone tell me in simpler terms such as 1-2 drops in 16 oz. Water?

Replied by Self

You could add one drop of 2.3% MB to 18 cups of water (which also equals one gallon and one pint of water) and take one cup of this twice a day. You do not want to take too much MB or it can make your mind too active. Don't forget to take 2,000 milligrams (or 2 grams) of vitamin C (sodium ascorbate) a day too.

Replied by Tom
(Regina, Sk)

I'm assuming you meant to ask "... To end up at 0.1% concentration"?
If so, then this means that you need 22 times as much water volume to dilute as the amount you're wanting to dilute, since. 1% IS 1/23 of 2.3%. The total of 1 part solution and 22 parts water will equal the total watered-down volume 23 parts. To make the math a lot easier, one can just dilute 20:1, ie 20 parts water to 1 part solution and be very close. Measurement quantities:
20 metric drops per ml
5 ml per teaspoon (Tsp)
3 Tsp per tablespoon (Tbsp)
2 tablespoons per ounce
Thus 600 drops, or 30 ml, or 6 teaspoons per ounce. 1 cup= 8 oz= 4800 drops= 240 ml= 48 Tsp= 16 Tbsp

So there it is. Using the 20 ratio for dilution, to get 1 cup watered down solution, just dilute 240/20= 12 ml of 2. 3% (just use a kitchen measuring spoon of 1 Tsp= 5ml) INTO the 1 cup of water.

Replied by Claudia
(Calgary, Alberta , Canada)

I got my methylene blue from the pharmacy. The pharmacist had absolutely no idea how to provide a 0.1% solution, so what I have now is 50mg/ml. Does anyone have any idea how to convert this? TIA.

Replied by Amazinggrace
(Yucca Valley, Ca)

I don't have metric measuring instruments, so to get a 1:22 ratio, I used one Tablespoon of methylene blue and 22 Tablespoons of water. 22 Tablespoons equals 1 and a quarter cups plus 2 Tablespoons. (Derived from 16 T. = 1 Cup)

Replied by Randy
(Myrtle Beach, Sc)

Does anyone know how many drops of the diluted. 1% of the MB one would have to take for it to have an MAOI effect?

Also, would anyone know what the conversion would equate to of X amount of drops of. 1% solution of MB to X amount of mcg's or mg's of MB?

Replied by Randy
(Myrtle Beach, Sc)

I also should have added to my post about that I do know that MB can have MAOI properties but I do not know if it has those properties at the suggested drops of. 1% solution of anywhere between 3-8 drops on this site that is suggested. I think it would be wise if anyone could determine how many drops it would take at the. 1% solution to have MAOI effects.

Maybe Ted could weigh in on this. Reason being, if someone were to ridiculously experiment with many more drops and get in the range of it acting as an MAOI, then it is dangerous to do so if in particular that you are taking it along with an SSRI antidepressant.

To be on the safe side might as well include if taken with an NRI as well. Do your own web research to confirm this. I do take MB for added energy but I also take more drops than 8 with no adverse effects. I'm not recommending anyone else take more than 8. Everyone is different... Plus I also am not on any antidepressant. Just a word of caution here if anyone is unaware of the MAOI effects of MB and not to mix with AD's if in fact you are getting in range with the drops to have it act as an MAOI.

Replied by David
(Nerja, Malaga/spain)

I have 100mg MB powder. Do anyone know how to much 0.1 solution this will make? Do I just mix 1ml with 1l water?

Replied by J.park
(Cerritos, Ca)

I'm new to this site, so I just saw your message very late & realized that, as I said above in my writing, there is quite a confusion in % of MB.

You can calculate the percentage stuff using the same formula: % = g/cc -> cc = g/%:

Since you know g=0.1(100mg), %=0.001,

cc = g/% = 0.1/0.001 = 100.

So you'd make 100cc(mL) of 0.1% solution of MB.

Warning: in above formula 'g' must be in grams and % must be in "fraction" as the calculation shows.

Replied by J.park
(Cerritos, Ca)

Maybe I didn't make it clear in my previous writing,

you just put the 100mg MB into a graduated container and add distilled water to fill up to 100cc(mL), the total volume is to be 100cc when completely dissolved (which include MB & water of course).

Replied by Leanne

What about putting it on the skin. I am just hearing about the benefits of MB for skincare. Thanks!

Replied by Art
926 posts

In reply to Leanne (Ca),

Topical methylene blue is difficult because it stains your skin blue and for that matter, some painted surfaces and stone such as marble so you have to be careful handling methylene blue. If the topical application is for fungus, borax might be worth considering or the borax and diluted hydrogen peroxide which do not stain the skin.


Replied by Frances
(Cabarlah, Qld.)

Recent research has been published about methylene blue : Common antioxidant could slow symptoms of aging in human skin. The study was published online in the journal Scientific Reports on May 30,2017. The article is available on several web sites.

Diluting Methylene Blue
Posted by Merryanne (Orange City, Florida, USA) on 10/10/2009 120 posts

Hello, this is Merryanne in Central Florida,,,I order of Methylene Blue has arrived,,,I ordered a 32oz bottle,,will I have a 32oz bottle with a little bit of powder in it,,,I read the directions and your to fill with distilled water to the top. I called to find out what percentage the mix would be,,but the girl does not know..I contacted the manufacture and left a message to give me that information. I ordered form a company in OH that thinks they are the solution ...Does anyone have any clue about this,,what the mix solution might be???merryanne

Replied by Merryanne
(Orange City, Florida, USA)
120 posts

This is Merryanne,,,I received a call back from the manufactor of the 32oz contanier with a little methylene blue powder in it--he said that after filling with water you have a 2.3% solution. That did answer my question,,but now I have several more (since I did not take the call my message taker did) like how long is that going to be good for, I will have to dilut some of it to 0.1%. So I am going to call him back on Wednesday (when I am off work) and find out how much of his powder it takes to make a 0.1% solution. Then I want be wasting the powder,,because 32oz of 2.3% diluted down to 0.1% is a lots, and lots of solution. And I don't think the shelf life is long enough,,I will ask if it can be frozen. I will let you know what they say.