The Surprising Health Benefits of Methylene Blue

| Modified on May 30, 2023
Chronic Fatigue
Posted by Cynthia (California) on 09/12/2016
5 out of 5 stars

I found that methylene blue works great for chronic fatigue. It was like someone hit my on switch. My energy level and thinking improved drastically and I was easily able to give up caffeine. However, the reason why methylene blue was able to work so well for me is that my chronic fatigue was due the fact that methylene blue treats mitochondria damage, and I have mitochondria damage from taking Cipro. Never take Cipro.

Methylene Blue Tips
Posted by Kenny (Ga.) on 06/11/2021
5 out of 5 stars

Have been using methylene blue for 2 months now with great results. I am using a teaspoon of baking soda about an hour after meals in an effort to get off of Prilosec. In doing this I have noticed that my urine is no longer blue. Anybody else noticed this after using baking soda with methylene blue?

Benign Skin Lesions
Posted by Lisa (Hawaii) on 08/17/2017
5 out of 5 stars

METHYLENE BLUE, I have been using MB topically on benign skin lesions, the doctor had been freezing them off, but they eventually come back and the freezing is painful. So I just applied the 2.3% (fish stuff) directly on the spots. They take up the dye, and dry up, I reapplied it to the larger spots a few times, the small spots just healed up very fast. skin is looking great, no pain.

Methylene Blue Baths
Posted by Fiona (Tustin, Ca) on 10/14/2013
5 out of 5 stars

I have used Methylene Blue for orally and a bath. Orally taking made me feel better shortly and then I got depressed shortly. Ever since then I use it for bath. I realized it colored blue much darker on impure cells. And then it fell off. I had bad breakouts but the grip was very strong. I painted methylene blue on top of the affected skin. A few hours later it would lose the grip and fall off. I have been using for bath about 2 months. It gave me much better brain function and also it helps me peel off dead skin much more faster and effective and skin becomes whiter and pinkier and a lot firmer.

I think using MB for bath almost gives no side effects. Very safe. I am planning to use it as long as I live.

If you had some bad reaction on using MB such as depression I would recommend using on the biggest organ that human has. Which is skin.. If you start detoxing skin, the overall toxic load on the body decreased. I really think a bath with methylene blue gives so many healing properties.

On top of methylene blue, I am using MMS2 which is pool shock (calcium hypochlorite) I believe orally you take this and see yourself what is coming out of your body. Extremely powerful yet cheap.

After suffering 35 years, and researching I found out the healing power is not according to the price or wellknown drug. I believe you heal quicker than the disease spread, then you are on the right track.

MMS2 is very powerful it cures AIDS or Lyme etc.. you can read about mms on Jim Humble's website. When you detox, the body uses up so much iodine. Make sure you take enough of iodine.

Multiple Cures
Posted by Bp (Edmonton, Ab, Canada) on 09/17/2011
5 out of 5 stars

I've only been taking methylene blue for about two weeks, so I can't yet speak to long-term benefits or side-effects. But its positive results for me in this little time have been remarkable.

I've been suffering with depression and numerous physical problems for several years, to the point of being nearly bedridden at times, and being unable to function productively more days than not. I've tried dozens and dozens of natural remedies, with only limited effect.

When I began taking the methylene blue, I had a couple of days of discomfort in the area of one kidney. But within a couple of days, this had subsided, and I currently have the strongest physical and mental health I've had in years! My mood is joyful, and I have much improved focus when reading. The pains in my spleen area have virtually disappeared, I can breath comfortably at rest (my breathing was laboured before), and I have gone from needing 9 or 10 hours of sleep a night to needing only 6 or 7 to get by comfortably.

MB isn't a cure-all -- I still have back problems, and skin issues, and some other symptoms from congenital/genetic issues. But, based on my own experience, I recommend trying it if you have had problems with candida or parasites, anything spleen-related, depression without obvious cause, persistent breathing problems, or thyroid/glandular disfunction.

I dilute one drop of the pet-store MB into four litres of water (two full 2-litre pop-bottles), and take between a half-cup and a full cup, with extra water added to further dilute the dose, once or twice daily. Since MB is used to disinfect standing water, it shouldn't need to be refrigerated, either.

Parkinson's Disease
Posted by Liz (Boston, Ma) on 07/10/2016

You have to be able to think outside the box.

All of the questions you asked can be answered by doing some online research. I've been an EC devotee for many, many years, but I never stop doing my 'homework'. I read, read, read *everywhere* online.

With natural remedies, quite often, there isn't a real answer to 'why' something works--it just does.

Chronic Bladder Infections
Posted by MHO (Provo, UT) on 03/18/2022
5 out of 5 stars

I am an intermittent catheter user, therefore, I have chronic bladder infections. Ever since I began using Methylene Blue I have stopped getting UTIs. I use Methylene Blue 1% solution. The normal dose is 10 drops in water morning and night. I only need 2 drops morning and night. I use a straw to drink it so my teeth won't turn blue. It has the added benefit of stopping my candida symptoms.

Having said this, I am also very careful about what I eat: no sugar or fruit of any kind. I don't use any artificial sweeteners. I avoid wheat and other grains. I eat canned beans, eggs, fish, chicken, vegetables, and brown rice. I have to avoid nuts.

Posted by Susanna (Skagit, Wa) on 12/22/2017
5 out of 5 stars

Research indicates Vitamin C may inhibit Methylene Blue's killing of Candida

Ted's advice on many areas of health have been of great assistance to me. I became interested in trying Methylene Blue for attacking my systemic Candida, and did some additional research. I came across a study that indicates that taking Vitamin C with MB may decrease the effectiveness of its impact on Candida. The research is found at

The relevant quote is halfway through the abstract: "... sensitivity of Candida cells to MB could be rescued upon the supplementation of ascorbic acid, an antioxidant." In the context of the abstract, this "rescue" seemed to be contrary to the intent of killing Candida cells.

Therefore, I began to take MB 1 drop twice a day (along with BHT), but taking ascorbic acid at least two hours later. My reasoning was taking such a small dose had no risk of side effects (coloring eye, etc.), but that any potential impact on Candida would not be lessened by the ascorbic acid.

I understand that Ted is not currently up to responding, but am hopeful that this information may help others, if you or someone may take a look at it and comment on how to take MB and Vitamin C (perhaps 2 hours between the two?).

Hoping this may assist others in recovery from Candidiasis;

Sincerely, Susanna

Cytokine Storms
Posted by Bill (Philippines) on 01/15/2021

Using Methylene Blue is not just a hypothesis.Regarding using methylene blue(MB) against COVID-19 ARDS, there is an Indian doctor, Dr Deepak Golwalkar, who, as a pulmonologist and lung specialist, has been using his nebulized/sublingual MB treatment for quite a while and with great success for his pneumonia patients and for his COVID-19 patients with ARDS. Here is his website, which details his treatment:

Interestingly, Dr Golwalkar also uses exactly the same concentration of MB for nebulizing -- 0.1% methylene blue -- which is the same concentration that Ted from Bangkok recommends.

Posted by Daboo (Amherst, MA) on 02/27/2014
5 out of 5 stars

I was taking Methylene Blue (12-13 drops in 8 ounces of water) with a thousand milligrams of vitamin C for about a week & I noticed the severity of my candida related itchy skin was reduced, I then upped my dosage by a few more drops per day (14-15 drops) in about 9-10 ounces of water, and a few hours later my stool was loaded with dead candida overgrowth! I normally have bad constipation but this time my "relief" was smooth and easy I was amazed. Also, I use the Methylene blue stain directly on my skin where I have itchy candida rashes, yes it stains! But only for a few days & most of it will wash off with soap and water, so use it where it cannot be seen, and it will take you itchy rash away with relief within 10-15 minutes and the relief will last for like a week, until the bugs send out a new invading force! I have also use Methylene Blue in more diluted parts for itchy skin in more visible areas with relief & I found it is also good for tooth aches.

P.S when I take it in strong doses your urine turns blue for about a day, but when you stop taking it it turns back to normal & I take vit C 500-1000 mill and have had no problems with my eye coloring, which I also heard is reversible if you should happen to have that happen to you.

Heart Palpitations, Anxiety, Panic
Posted by Califlybaby (Utah) on 01/31/2023
5 out of 5 stars

Interesting! I'm taking Methylene Blue and it actually stops my heart palpitations. It has also stopped anxiety and panic attacks. I am taking the 1% from Compass Laboratory. About 20 drops once or twice a day.

Multiple Cures
Posted by Terry Jacks (Texas) on 12/16/2022
5 out of 5 stars

It's not working very well for you? Based on your statement about 3-5 drops of 1%, I can see why. You should consider taking AT LEAST 15mg per day, which is 30 drops of 1% strength. The typical recommended dose is 40 to 360mg. I think 360 is a bit high, but 40 is fine. I take 30 to 40mg per day with great results for energy, attitude, skin condition, muscle strength gains, diabetic neuropathy, calmness, sleep quality, blood glucose control, eyesight, circulation and lasting energy during hard work.

Methylene Blue Side Effects
Posted by Big C (Traveller) on 06/30/2014

It could be part of a Herxheimer reaction where te fungus/parasites are dying off and releasing their toxins into the blood.

You really should read up everything you can before taking anything, inform yourself first so YOU know what YOU are doing.

Depression, Anxiety
Posted by Pam (New Zealand) on 04/01/2023

Thanks for that, Barry, I still take it every day and bought enough powder to last me decades and considering I am 83 now shows optimism if nothing else, ha ha. Just started my 3rd year living with bowel cancer, diagnosed in December 2020. I refused surgery. Have Rife machine and take onboard anything that checks out positive against cancer. Eat organic or spray free etc.etc.!

Prostate Cancer
Posted by Art (California) on 12/30/2022 1670 posts


On the chance that you don't get the replies you are seeking, two other potential adjunctive treatments for PC is Melatonin and Berberine as discussed in the following links below:

A relevant quote :

' This is the first demonstration showing that melatonin impedes metastasis of prostate cancer by suppressing MMP-13 expression in both in vitro and in vivo models. Thus, melatonin is promising in the management of prostate cancer metastasis and deserves to undergo clinical investigations. '

A relevant quote :

' Recently, melatonin emerges as a prospective therapeutic agent with a series of beneficial effects on human cancers over a wide range of concentrations and tumor types. In this review article, we predominantly discuss the anti-tumor effects of melatonin on human PCa. The underlying mechanisms of how melatonin inhibits the growth and progression of PCa were related to the promotion of AR exclusion, activation of MT1 signaling, modulation of PCa metabolism, inhibition of angiogenesis, regulation of neuroendocrine differentiation, induction of apoptosis. Moreover, melatonin also exerts synergistic benefits while incorporating with other chemotherapeutic agents and is an effective adjuvant to androgen depletion therapy. Melatonin is also hopeful to be a noninvasive biomarker for predicting PCa since a low urinary melatonin level is highly correlated to the incidence of PCa. '

A relevant quote from the study :

' In a multivariate analysis, melatonin administration proved to be an independent prognostic factor and reduced the risk of death of PCa patients by more than twice (p < 0.0001). '

Another consideration is Berberine :

A relevant quote :

' Berberine inhibits prostate cancer cell growth and induces apoptosis. A, structure of berberine. B, BBR inhibited the growth of LNCaP. Cells were treated with various concentrations of BBR for 24, 48, or 72 hours. MTT assay was conducted to determine cell viability. The viability of control cells was set at 100%. The data plotted are mean ± SD; n = 8. C, BBR induced apoptosis in LNCaP. Apoptosis was quantitated by cell death ELISA in LNCaP cells treated with indicated concentrations of BBR for 24 hours. Data plotted are mean ± SD; n = 3. *, P < 0.05; **, P < 0.01. '

A relevant study quote :

' BBR has been shown to suppress the capacity of prostate cancer cells to spread and infiltrate, these cells being strongly metastatic [49]. The inhibitory activity of BBR resulted in a substantial reduction in the expression of a panel of mesenchymal genes that control developmental EMT. High BMP7, NODAL, and Snail gene expression in metastatic prostate cancer tissues is associated with shorter survival in patients with prostate cancers and offers potential therapeutic targets among the EMT-related genes downregulated by BBR [49] (Table 2). '

A relevant quote from this review :

' Importantly, the active ingredient of berberine has clear inhibitory effects on various cancers, including colorectal cancer, lung cancer, ovarian cancer, prostate cancer, liver cancer, and cervical cancer. '

I have always felt that topically applied colloidal silver (CS) with a DMSO primer to allow the CS to penetrate the skin and dermal layers in the area of the prostate would be useful, but it is only speculation on my part so I can't even recommend it, just me thinking out loud.


Topical Methylene Blue
Posted by Art (California ) on 06/05/2017 1670 posts
0 out of 5 stars


In reply to Leanne (Ca),

Topical methylene blue is difficult because it stains your skin blue and for that matter, some painted surfaces and stone such as marble so you have to be careful handling methylene blue. If the topical application is for fungus, borax might be worth considering or the borax and diluted hydrogen peroxide which do not stain the skin.


Anxiety, Panic Attacks, Intestinal Cysts
Posted by Brass Player (Sw Usa) on 01/12/2017

I also thought I had Lyme disease. It turned out that I had an ongoing toxic mold exposure, that nearly killed me before I found out what it was (and not from a doctor) and got out of my house that had a hidden water leak. Lyme and CIRS (toxic mold illness) have extremely similar symptoms, and common mis-diagnoses are CFS, Fibromyalgia, and any other "syndrome" disease.

Anyone whose doctor says "it must be a virus" yet it never goes away, should go read survivingmold site. Water damaged buildings are common but the vast majority of physicians are not cognizant that 24% of the population has a genetic haplotype that is susceptible to the toxins. So only 1/4 of the people in a water damaged building will be extremely ill, and the other 3/4 either not ill or only with niggling minor illnesses. Well worth a look for the CFS/Fibro people. If I hadn't found out it was mold, I'd be dead.

Multiple Cures
Posted by Heather (San Diego, Ca) on 03/08/2013
5 out of 5 stars

Thank you for posting this. I'd been looking into Methylene Blue (MB) for antifungal/antibiotic/antiviral uses, and noted that it seemed to clear up brain fog and was being used in clinical trials for a variety of brain-related issues (which I have to some degree). I also had multiple painful cysts (one each on an ovary, liver, kidney, in diaphram area and a breast.) The breast one seemed to go away on it's own but the others persisted for 9 months, sometimes doubling me over in agony. Usually though, they only hurt if I or my doctor pressed on them.

After a week on MB, I noticed the abdominal area cysts hadn't been bothering me, so I began pressing on all the parts that hurt, and no pain. I'm assuming they are now cleared up. Note that two weeks prior to MB, I finally took a course of antibiotics, which may have helped, but the pain was still there, and they still hurt when I pressed on them even a week after discontinuing the antibiotics.

Other supplements I take are Lugols 5% (average 1 drop per day); daily, a half dose of a good quality, high b vitamin multi, vitamin D 1500-2000 per day, N-A-C, Milk Thistle, Lysine, 3-4 grams Vitamin C and melatonin; Zinc, selenium lithium aspartate (5 mg) are taken 3-4 x per week. Also, I've been faithfully making Ted's alkalzing formula 1/4 tsp baking soda with an acid (ACV, lemon juice, or for now, just the vitamin C crystals to take with the Methylene Blue). Additional baking soda taken on its own before bed.

Take a few low dose (usually 1/3 of lowest dose) Xanax and Trazadone for sleep or panic attacks as needed. (Once in past week.) Taking the MB in 2-5 drops, 2-3 x per day in the 0.1% solution recommended by this site (Ted). I've settled for now upon 2 drops but experimented a bit.

I've experienced reduced brain fog, increased ability to focus, recall of memories and vocabulary that were lost to the brain fog, deeper sleep, and less anxiety but not ruling out placebo effect (or the addition of Lysine) yet as I haven't been on it for months. I can only say that the cysts are not a placebo effect, as they were painful and I wasn't taking MB for them per se, although I did hope for improved general health due to possible viral/fungal/bacterial infection. I have traveled to jungles, etc. , in past and thought perhaps I picked up something US docs don't screen for.

Side effects I may be experiencing from Methylene Blue are headaches (mild, infrequent), dehydration - drinking lots more water, buzzing in brain - specifically the right side over temple, and sometimes on top of hear, stiffness in neck/ upper back. Except for the buzzing, the others may not be related at all. The brain buzzing is particulalry amplified by coffee and/or N-A-C. I've also been experiencing a buzzing in my lower legs (outside of calf) for a few days.

There's research on Methylene Blue that says it is an inhibitor of Tau protein aggregation. (From wiki: Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes.[1] When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease.

Melatonin also reduces tau hyperphosphorylation, at least in rat brain studies, so I'm going to taper off of melatonin (I've taken 9 grams for a year) for a while. It might somehow be related to the buzz effect too.

That's my report. I fully expect that the mental benefits from my lose dose Methylene Blue experience will be a fail/placebo, but I'm going to keep it up for two or three more months, just in case.

Posted by wildp (so cal) on 11/07/2022
5 out of 5 stars

Methylene Blue for Neuropathy

I am on 40 drops now, ramped up since 9/10/2022.... neuropathy feet waking up, color is great on both feet..... the one foot that was not neuropathic is going a bit faster cleaning the color and regaining feeling.

Methylene Blue Side Effects
Posted by A mercer (Fl) on 07/28/2022

Have you checked your iodine levels? Low iodine can occur while detoxing and should be added…low iodine can cause heart arrhythmias.

Parkinson's Disease
Posted by Jane (Fort Worth, TX) on 01/09/2009
4 out of 5 stars

Hi Ted,

I am amazed that after one and a half days of taking methylene blue with vitamin c my 85 year old dad, who has Parkinson's, initiated transfer to his wheelchair and needed much less assistance than yesterday. Yesterday he was not weight bearing much. This morning I did not pick him up to get in his chair, just guided him. I broke out into laughter of happiness!

Thank you a million for the information you provide on earthclinic. I love seeing the results!


Recommended Videos
Posted by Sam (Miami) on 01/17/2023
5 out of 5 stars

Oral Dosage For Methylene Blue - FLCCC Protocol Review

Here is the link to an excellent video on dosage. make sure you watch his Methylene Blue and Near InfraRed Light for Neuroprotection video as well.

Depression, Anxiety
Posted by Lisa (Perth, Western Australia) on 08/07/2022
5 out of 5 stars

My name is Lisa. I am 43 years old I want to share with you an experience with Methylene blue. I have been using it for 5 years. it is effective on depression and calm anxiety. I tried 2 types of Methylene blue -- powder as well as liquid. The liquid was much expensive in comparison to the powder but both have same results. For 2 years I have been using Methylene blue powder form. I was purchasing it from cztl.

Depression, Anxiety
Posted by Pam (Kamo) on 03/22/2023
5 out of 5 stars

This is Pam, my sincere apologies for getting this wrong. 1gm MB in 1 litre water which Dr Deepak told me could even be tap water (preferably filtered) as MB will deal with anything in it. This will give you .01%, think that is correct now. Whatever this was what Dr Deepak wrote to me when he so kindly answered my letter asking for help. I measure 1gm into water and add to a 1 litre brown glass bottle. I bought some small wide neck 5 gm bottle to put 1gm powder in for this purpose makes things easier but do cover worktop well its amazing for infiltrating everywhere it shouldn't! I take 10 drops in the morning and 11 drops late afternoon, excellent stuff.

My daughter got rid of all her painful, aching bones (Lyme) disease using this 10 drops 2x daily and swears by it. now. I use her method of putting the drops into a shot glass and have a mugful of water with 1gm Vit C some before and rest straight after taking the shot. Yes, lemon juice squeezed onto any spillage dilutes it immediately, then mop up with anything you can throw away.

Depression, Anxiety
Posted by barry (wisconsin) on 03/23/2023
5 out of 5 stars

Hello Pam, have you read the book "miracle in the hills"? Dr. Mary Sloop. A woman had cancer in her intestines and the doctor operated and closed her up saying it was inoperable, so the country doctor gave her MB and she lived at least 40 years. It is on page 43 chapter 9.

Cytokine Storms
Posted by Dame Nikki (California) on 08/23/2021


DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis


Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various inflammatory conditions as well as for cancer. Despite its widespread use, there is a paucity of data regarding its safety and efficacy as well as its mechanism of action in human cells. Herein, we demonstrate that DMSO has ex-vivo anti-inflammatory activity using Escherichia coli- (E. coli) and herpes simplex virus-1 (HSV-1)-stimulated whole human blood. Specifically, we found that between 0.5%-2%, DMSO significantly suppressed the expression of many pro-inflammatory cytokines/chemokines and prostaglandin E2 (PGE2). However, a significant reduction in monocyte viability was also observed at 2% DMSO, suggesting a narrow window of efficacy. Anti-inflammatory concentrations of DMSO suppressed E. coli-induced ERK1/2, p38, JNK and Akt phosphorylation, suggesting DMSO acts on these signaling pathways to suppress inflammatory cytokine/chemokine production. Although DMSO induces the differentiation of B16/F10 melanoma cells in vitro, topical administration of DMSO to mice subcutaneously implanted with B16 melanoma cells was ineffective at reducing tumor growth, DMSO was also found to block mouse macrophages from polarizing to either an M1- or an M2-phenotype, which may contribute to its inability to slow tumor growth. Topical administration of DMSO, however, significantly mitigated K/BxN serum-induced arthritis in mice, and this was associated with reduced levels of pro-inflammatory cytokines in the joints and white blood cell levels in the blood. Thus, while we cannot confirm the efficacy of DMSO as an anti-cancer agent, the use of DMSO in arthritis warrants further investigation to ascertain its therapeutic potential.

Posted by Marsh57 (Denver) on 09/18/2017
5 out of 5 stars

All the formulas for breaking down Methylene Blue 2.3% caused nightmares of high school math & science, resulting in an Excedrin PM headache lol. I took the info everyone provided and it averaged to be 1 part 2.3% MB : 22 - 23 parts distilled water.

Still afraid to try it, I called a friend of a friend who's a chemist - he said 1 part MB to 23 parts water. (The K--don is 2.3% water solution, zinc free.) I hope this helps!

Anxiety, Panic Attacks, Intestinal Cysts
Posted by Dee (Florida) on 08/08/2022

Lufenuron clears up morgellons, because it kills candida and fungus infections. It also eliminates fleas in dogs and cats, because it breaks down the chitin which occurs in both insect and fungus as their protective shells!

Posted by Wat (Digby, Nova Scotia) on 08/29/2012 10 posts

more likely mis-information and half truths from FDA and Big Pharma research studies... In any event once your clean of their poisons you should have no further excuses NO! So use it then.

Posted by Ted (Bangkok, Thailand) on 08/11/2010 385 posts
5 out of 5 stars

Dear Kevin:

Methylene blue does effect cancer growth by turning the cancer tumors into aerobic, which stops their growth that way as cancer in general are aerobic. Methylene blue is acquired from stores that sell aquarium fishes. They usually have methylene blue 1%, whereby we reduce them by adding 1 parts methylene blue with 9 parts water, should get a relatively safe concentration. Then we can add methylene blue drops such as 8 drops and slowly add more so if there is no side effects. In Vietnam war they actually used far more methylene blue to treat malaria, such as methylene powder in milligram to gram doses. The methylene blue is synergistic with large dose vitamin C. What I do know for stage IV cancer, which is cachexia cancer, is B50 vitamin B complex, or B6 200 mg for example can reduce some of this cancer cachexia. The other is the use of Hydrochloric acid concentrated, at 8 drops per 250 cc of water and to that I will add between 4 to 8 drops of methylene blue and take this for an entire day until the cancer cachexia goes away. Another observation to restore the appetite and stopped cancer cachexia that I have found is B5 panthenol, or a possible replacement, pantothenic acid to be helpful. What I do not like about pantothenic acid is the calcium form since the get cancer worse. If it was possible for the methylene blue 0.1% is injected a 1 cc, into the tumor cells that could have done it's job also in staving off tumor, but that's just a theory, by interfering with cancer fermentation. In any case, there are other ways to resolving cancer cachexia such as megestrol which is progesterone hormone, if taken at fairly large dose such as 250 mg for example, or applied to the skin as safer means might actually stop the cachexia by neutralizing what they call TNF, which is a cachectin hormone that causes your inability to eat. The liver's inability to function from lactic acid is another problem that can lead to the condition also. A methylene blue is obtainable from a local chemist, a chemical company , a local aquarium shop, or a scientific supply store, or perhaps a school supply store where they do the slides to stain the samples using a 1% methylene blue solution.


Diluting Methylene Blue
Posted by Bill (San Fernando, Philippines) on 08/05/2014
5 out of 5 stars

Hi Pankaj...I also use Methylene Blue bought from an aquarium shop. This also has no spec showing the percentage MB in this solution. But, generally, all Methylene Blue sold from aquariums is at 1% strength.

So what I did was just to assume that it was 1% solution.

The way I now take Methylene Blue with water is like this:

Say that I want to take 5 drops of 0.1% MB solution.

For five drops of 0.1% MB I first add 1 drop of 1% MB to a glass of water. This is equivalent to 10 drops of 0.1% MB.

Then I pour half the water out of the glass.

So you are now left with 1/2 drop 1% MB or 5 drops of 0.1% MB in solution which is your dose.

Usually, I take about 10 to 15 drops whenever needed. Always add or supplement at least 1000 mgs of Vitamin C with the methylene blue solution -- the vitamin c stops your eyes and urine turning blue. MB is a harmless stain that is also used in science to identify carbohydrates by turning blue.

Parkinson's Disease
Posted by Art (California ) on 07/11/2016 1670 posts


If you are concerned about the quality of the methylene blue you are considering using for your mom, you can purchase it through a chemical supplier like Sigma Aldrich where they will have a certificate of analysis, a spec sheet and a certificate of origin so you know exactly what you are buying and its purity. It will cost a little more and won't be as easy to get, but you know exactly what you are getting.®ion=US

Another option is to speak to your mother's doctor about it and see if he/she will write a prescription that can be filled at a compounding pharmacy to your doctors specifications.

You will have to do some research on your own to get a better understanding of how MB may be helpful for neurodegenarative diseases and what dose would be best in your mother's case. MB has a good safety profile and probably a very good safety profile at the dose your mother would likely use.

PD has multiple forms and one form is directly associated to longer term pesticide exposure while others do not have this association. Some progress slower than others.

In the mean time, you might look into vitamin D as it relates to Parkinson's Disease. There are many studies available on PubMed that suggest that the population in general is low on serum 25 (OH)D, but even lower among people with Parkinson's Disease and that the lower the serum 25(OH)D, the worse the symptoms. A couple of the studies go so far as to say that the proper serum level of 25(OH)D may slow disease progression and help protect neurons in the brain.

There are many supplements that show benefit for people living with PD. I am currently compiling a lengthy list of about 50 of these supplements and gathering information on them trying to see which ones are most likely to have actual benefit in humans. Many supplements have only been tested in rodents and consequently would fall lower on the list. It is a work in progress and will take me sometime before I am finished. Having a very good to excellent safety profile is a very important consideration for me because that will improve the odds of having a doctor approve a supplement for a patient.

The topical magnesium oil is frequently noted for helping to relax stiff or cramping muscles in PD and is readily available at many health food stores and on the web. It also has other health benefits and can build up the bodies supply of magnesium while limiting the potential for diarrhea.

There are many supplements that show potential to be of use in PD, but you'll have to do your research and determine what will be compatible with for your mother.

In any case it is important that you get approval and supervision from your mother's doctor before using any supplements to make sure that they are compatible with the prescription meds that she is taking.


Methylene Blue Solution Dosage
Posted by Bill (Philippines) on 01/11/2023

Hi Mike,

To make a 1% solution of Methylene Blue, add your 1 gram of MB powder to 100 ml of distilled water. This will give you 100ml of 1% Methylene Blue solution.

To make a 0.1% solution of Methylene Blue, add your 1 gram of MB powder to 1000 ml of distilled water. This gives you 1 liter of 0.1% Methylene Blue solution.

Cytokine Storms
Posted by Tim (Minnesota) on 01/15/2021 7 posts

The only drug known to inhibit the excessive production of reactive species and cytokines is methylene blue, a low-cost dye with antiseptic properties used effectively to treat malaria, urinary tract infections, septic shock, and methaemoglobinaemia.The relatively poor efficacy of anti-cytokine drugs is explained by the fact that they act on one or a few of the dozens of cytokines involved, and because other mediators of inflammation – reactive oxygen and nitrogen species – are not targeted. When produced in excess, reactive species cause extensive cell and tissue damage.