Melatonin Protocol for COVID-19

I mentioned in another thread that I would report if I got Covid-19 because that would indicate that melatonin does not work as a prophylactic as I am taking 106 mg+ per evening.

Well, last night at 8:00pm I started feeling off with pain in my chest, shoulders, back and upper legs. By 9:00pm, I was having severe chills and decided to take my daily melatonin a little earlier than normal, but I also decided to bump my dose up to around 125 mg and immediately went to bed. I put 4 blankets on and still felt cold so I pulled the blankets over my head to try and warm up faster, but when I put my face under the covers, it felt sort of like when you open up an oven door when you have had a turkey cooking for hours and that heat hits your face, so I pulled the blankets back down to uncover my head as I clearly had a fever, but was too cold to get up and take my temperature. I slept restlessly and each time I woke up, I felt worse with more pain in my joints, shoulders, legs and my hands and fingers felt like I had severe arthritis. My chest and back hurt even more than earlier and I could not take a deep breath without significant pain. I can say with complete certainty, I have never felt anything like this before. I also noticed I was getting little indications that my legs wanted to cramp up, but I could not get myself to get up and get the mag oil spray from the bathroom, I was just too cold!

I woke up at 8:00 am and with the time change, that would have been 10 hours since I first noticed I was sick. In all of my life, I have never had a cold or flu come on so quickly as I felt perfectly normal at 7:00 pm last night. I finally got up at 9:00 am and had a lot of congestion in my chest and surprisingly, for me, was able to cough most or all of it up. Usually, when I have that amount of congestion, it means I am going to be coughing for a month or longer. I decided to take a long shower and during the shower, I noticed that I felt almost normal except for the chest pain when I would try and take a deep breath. By the time I got out of the shower, I felt really good, but I decided it might be better for me to go back to bed rather than go for my walk.

I don't know for sure that this was covid as I had no test, but I feel as certain as I can that it was. I've never had symptoms quite like these before and the arthritic feeling hands is an absolute first. Sitting here typing, I also notice that it no longer hurts to take a deep breath and I feel normal! No more pain in my joints, no more chest pain, no more back pain, and no more congestion!

If this is covid, I will say that melatonin does not seem to prevent it, but neither does the vaccine. My understanding of the vaccine is that you can still get covid except it is supposed to be milder and not life-threatening or very similar to melatonin.

I am taking 20 mg doses throughout today and will likely continue that for possibly a week and then go back to my regular night dosing. I had previously mentioned that you should not throw your melatonin away just because you get a vaccine and I still feel that way because if you do get covid after being vaccinated, melatonin if used right away, looks likely to make that covid infection even milder.

I am glad I found Dr. Neel and his melatonin protocol because only having to put up with covid for 12 hours is wonderful! I think it is worth mentioning that I was not taking vitamin C or D, lysine, iodine or quercetin. I was taking zinc though.

I will update if things change as I know I will carry this virus for at least a week or more so I will stay on top of my melatonin dosing. Dr. Neel did mention that melatonin could work as a stand alone treatment for covid and my experience tends to confirm his statement.

I am not aware of any other treatment for covid that can reverse it so dramatically in just 12 hours!

Although there is so much more I can write about melatonin, I am only going to write one more post about it on EC because I think people just get tired of hearing about melatonin, no matter how many health issues it can be useful for.

Art

Hi guys!

I am happy to report that I and my family are on the other side of Covid, at least til our immunity wanes.

We were doing a variety of Coronavirus preventatives around my house. My husband and I have taken coconut oil daily since last March. My husband and daughter have taken astragalus root that whole time as well. We take vitamin D intermittently, and even in winter my husband and kids get lots of outside time. I have been taking 15 mg of melatonin at night for quite a while.

Then we got Covid.

None of us had a cough. Several of us lost sense of smell. Adults had significant fatigue. One child had a fever for one day. Several of us had sinus burning pain and eye pain. Headaches were common. I never registered a fever but felt flu like for a couple of days.

At the very first sign of illness, especially since we realized we had probably been exposed to COVID, I put everyone on the appropriate amount of melatonin (1gm/kg body weight every 24 hours, divided into four doses.) We also took 50 mcg of zinc, 1-2 grams of vitamin C, vitamin D and 2 quercetin capsules. We ate a lot soup and drank tea with honey. Appetites were not amazing, so I just focused on fluids. I had just gotten an amazing deal and stocked up on organic orange juice, too, so that was handy. Everyone rested as much as needed.

We did use some tylenol, ibuprofen and alka seltzer (never at the same time! ) for fever and aches. Alka seltzer seemed to work the best but I did NOT give it to children. Covid is new and aspirin has a history of causing Reye's Syndrome for some children with some viruses (like flu and chicken pox.)

It may be my imagination but I think I could feel the melatonin wearing off. When I was close to redosing time I would notice that I was feeling worse. I did take an extra dose or two in the middle of the night sometimes.

My mother in law, who is in poor health and lives with us, never had any symptoms. I gave her the same protocol that we took ourselves, in hopes of nipping it in the bud if she began with symptoms, which she never did.

I had some concerns about high dose melatonin (HDM) and its blood thinning properties. I am a bleeder because I have chronic low platelets. I didn't have any bleeding trouble with the HDM. My 9 year old is prone to nosebleeds but they did not increase in frequency during HDM. I don't recall him having any at all during that time. My mother in law is on xeralto and didn't have any trouble with HDM. This is descriptive though, not prescriptive.

While astragalus, melatonin, and coconut oil were part of our preventatives, they didn't prevent the disease. But perhaps they made symptoms lighter? I don't know.

I do think the earlier treating any illness begins, the better. It seems the viruses might get less of a foothold.

I think an over taxed immune system puts one at greater risk for getting a bad case of anything. Good nutrition, stress management, enough sleep, fresh air and exercise are all important for that. But honestly that can be really difficult for many people to accomplish. I'm just making an observation.

I have known some hale and hearty people get seriously sick. A naturopathic local doctor who was doing tons of preventatives and being super careful still got covid and got pretty sick.

I don't think there needs to be guilt associated with getting sick, for some failure of preventatives. We are humans and sickness happens to most everyone. When we are sick sometimes we have time to regroup our priorities, read a book we have wanted to read, and then take care of others when we are well.

At the end of the day, I am thankful we made it through relatively unscathed. I would use the same remedies again.

This is only one story of so many covid stories. It isn't a recommendation for anyone, but a “this is what seemed to work for us” story.

~Mama to Many~

Sorry to say, but back when was polio, pharmaceutical companies weren't yet motivated and controlled by Big Money. Back then they were developing vaccines for one and only purpose, to protect. Today is not about protection at all. It's about money and it's about undercovered agendas. Pfizer themselves says that their vaccines (and obviously Moderna and the rest..) DO NOT PROTECT, but only "reduces" the symptoms, which is a lie. Facts prove it and without any doubt whatsoever - "vaccinated" get infected at a much higher rate than the non-vaccinated. Vaccines are a foreign to the body and the body is trying to reject it, and as a result the immune system weakens. Vaccines are an illusion. Vaccines are a Smoke in your eyes. Those who refuse to get this weapon called "vaccine" are people who have curious mind, those who do their own research before making a decision. Those are people with a creative mind. Those who think that a vaccine will create a barrier which will stop any virus, are fooling themselves. Your best protection is your OWN Immune System given to you by our Creator. Altering and Modifying the immune system is a very dangerous intervention which has probably very different purposes but protection.

This is a very important update regarding an RCT for melatonin and Covid-19!

I haven't updated this thread in awhile and now seems like a good time to do that. This very recent (June/2021) human study (RCT) shows that even a relatively low dose of melatonin (9 mg) divided into three doses throughout the day, reduces symptoms and speeds recovery in hospitalized Covid-19 patients. Here is a link to the full study which seems very impressive considering the very low dose that was used in these hospitalized Covid-19 patients. Keep in mind that Dr. Neel is using a dose of 1 mg of melatonin per kilogram of body weight, which is much higher than the 9 mg dose used in this study. In an 80 kilogram person ( 176 lbs), 1 mg per kg would equal a daily dose of 80 mg in divided doses.

https://www.sciencedirect.com/science/article/pii/S0188440921001417?via=ihub

Some of the highlights of this study:

1. Nobody died in the standard of care group or the standard of care plus melatonin group.

2. Meantime to release from the hospital was 8.15 days in the standard of care group and 4.65 days in the standard of care group plus Melatonin. (p-value = 0.021)

3. Patients in the melatonin group showed a return to baseline health sooner than control patients (15.09 ± 8.69 vs. 29.60 ± 21.12; p = 0.004).

4. There were no adverse events in the melatonin group.

5. Labored or difficult breathing (dyspnea) was significantly less in the melatonin group. ( p-value = 0.049)

6. Fatigue was significantly less in the melatonin group (p-value - 0.02)

7. Cough was significantly less in the melatonin group. ( p-value = .045)

8. The inflammatory marker CRP was significantly lower in the melatonin group (p-value = 0.045)

As you can see from these results melatonin plus standard of care was significantly better than standard of care alone. The downside here is the small size of the study group, but this still tends to confirm the very good results that Dr. Neel has reported in the over 1000 Covid-19 patients he has successfully treated using a significantly higher dose of melatonin (1 mg kg/bw/day) than this study which used just 9 mg/day. This is the first melatonin / Covid-19 study (RCT) that I have seen completed.

The Manila study has not completed yet, but that is an important study because they are only treating patients who already have Covid-19 pneumonia.I know I have said it before, but I am going to keep saying it, please don't throw your melatonin away just because you have been vaccinated! If the virus continues to mutate rapidly as it has shown it can, this is a good reason to keep melatonin on hand, even if it makes you sleepy the next day. Getting any rest is useful in a disease that is noted for causing sleep problems. People who have been vaccinated still have gotten Covid-19 and died.

Art

My daughter woke up with flu symptoms yesterday. Could be flu or covid. Her husband is an EMT and around covid all the time. He had been mildly ill a day or two earlier in the week.

She is nursing her four month old baby. I had her take 20 mg of melatonin 4 times a day. She had never taken melatonin before. She was surprised that it did not knock her out. It did not have a negative effect on her baby (who is also sick.) It did not hinder her ability to take care of her little one.

This is not prescriptive - just one person's positive experience. Happily, she is feeling much better today and still taking melatonin.

~Mama to Many~

Ever since I read about Dr. Neel's success with melatonin on this site, I began taking bigger doses of melatonin every night at bedtime and kept a large reserve of different melatonin brands for myself and my friends and family. So when I contracted covid at the beginning of December and I found out I had it I immediately started taking about 30mg 5 or 6 times a day.

I also increased my vitamin d, c, and zinc intake daily as well.

Before I knew I had the virus, I had a pretty bad headache, a bit of a fever, and had some chills and heat flashes. My stomach was slightly bubbly as well. That was the first 2 days. By the afternoon of the second day I found out I had covid. So that is when I started taking megadoses of melatonin. My headache and fever started to leave.

The next morning, I woke up virtually symptom free. I could feel it just a little bit in my lungs and would occasionally cough up a little bit of phlegm but that was it. I continued with megadosing melatonin and taking extra c, d, and zinc for the next 2 weeks or maybe a little bit longer.

Then I tapered everything down gradually until I got back to my normal routine. Now I just take 20-30 mg a night before bed. I really believe that the melatonin increase basically made me asymptomatic almost immediately.

I used several different brands of dissolvable lozenges that were between 2.5 and 12 mgs a lozenge.

Last night I got a call from a friend who has a friend who was just diagnosed with Covid-19 and was asking my friend if she was aware of any home remedies for Covid-19 as it was giving her a tremendous headache which she described as a 12 on a scale of 1 to 10. She said it was unbearable and her doctor had told her to take Tylenol, which she said did not touch it. She also said that her body ached in all of the joints and it was pretty unbearable to her.

I reminded my friend that Dr. Neel was using 1 mg of melatonin per kilogram of body weight. She said her friend weighed 170 pounds so that worked out just over 77 kg. She told her friend to take 80 mg of melatonin per day in 4 divided doses. Either her friend misunderstood or my friend did not say it correctly as her friend took 80 mg of melatonin every 6 hours to start with which equals 320 mg of melatonin per day! I got a phone call from my friend this morning telling me what her friend had done and she said she suffered no ill effects from that dose. She further said that her headache was down to a 2 and all of her body aches were gone.

I explained to my friend that the dose her friend used was more like the dosing that they were using in Manila. In any case, she told her friend that Dr. Neel was only recommending one fourth of the dose she had taken, so her friend told her that she was going to go down to a 90 mg per day dose in 3 divided doses of 30 mg each dose or 30 mg every 8 hours. Her friend told her that she was feeling so much better after taking the melatonin and it was not causing her any ill effects that she could tell. She further said that she will continue the 90 mg per day for at least 2 weeks or possibly 3 weeks to try and prevent Long Covid.

Art

Here's some more useful and surprising safety info in support of using melatonin for COVID-19.

It has already been recommended that melatonin dosage should be 1 mg/kg/day by Dr Neel. But, in the following research study, it is recommending 8 mg/kg/day divided into 5 sub-doses for COVID-19. The research study below also surprisingly says that melatonin at 8 mg/kg/day is "in the ranges used to treat septic patients clinically and is devoid of any adverse effect; thus, it is safe".

See below:

https://doi.org/10.32794/mr11250062

I find that dose of 8 mgs/kg/day very interesting. That also tells me that melatonin is very safe indeed at just 1mg/kg/day.

I've also found 12 research reviews on PubMed assessing and strongly recommending melatonin as a protocol for COVID-19 patients. These studies are all begging for permission from the FDA for melatonin to be studied for use in US hospitals. But the FDA/NIH are still not interested in doing the necessary research to prove that melatonin works against COVID-19. What's more, the FDA has known about melatonin's usefulness against COVID-19 since April/May 2019 when Dr Neel and others loudly informed the FDA of its hugely beneficial effects. I guess the FDA might be thinking that a successful, simple and cheap COVID-19 therapeutic like melatonin at this time might well hinder the ongoing vast sales of western vaccines all over the world. After all, if you have a successful and cheap natural therapeutic like melatonin that can revert your COVID-19 to ordinary, harmless flu then we wouldn't really need those vaccines. Right?

I came down with covid last week, with headaches and aches and pains and extreme chills being the primary symptoms. I had been following a vit d, vit c, quercitin, zinc and k2 regimen. I believe that helped lessen the effects. As I continued to worsen, I decided to try the Melatonin protocol. I decided on 60 mg divided into a dose of 20 mg morning, noon and night. I also added CBD oil to each dose. As of today, 11 days later, I am finally feeling better. No aches, pains or chills, no headache and my lungs are working well. I don't feel particularly strong yet, but I hope to continue to improve. I'm hoping this helps others. Those of us who can afford to self-treat are fortunate.

I will be posting about COVID-19 and how to get quick relief using mega doses of Melatonin. As you may know President Trump contracted COVID-19 in the White House and was treated with High doses of Melaton. Melatonin is safe in high doses. Dr Richard L. Neel from Texas has successfully treated thousands of COVID-19 patients, in fact the Dr's in the Philippines have also learn to treat patients with below doses of Melatonin.

Adults—100mg of melatonin daily. Take 20mg 3X daily & 40mg at bed time.

Children—Most don't need the melatonin. Those who have a fever or cough use: Age 0-2 yrs take a dose of 1-2mg daily 4X daily, if they need it. Once melatonin is given the fever usually goes away in 30 minutes after a dose or two.

Children—2-6 yrs Give 20mg daily with a 2-5mg 4X a day.

Children— 6-12 give 40mg daily with 5-10mg 4X a day.

Children—over 12 yrs give same dosage as adults.

Dr Neel has successfully treated patients with Anti-Depressant (SSRI) Fluvoxamine which also treats OCD, I don't know the dosage, however it should be short-term due to dangerous long-term side effects. Short term would not be addictive. To learn more about Dr Neel Google: Dr. Richard Neel & Melatonin. Dr Neel has 39yrs experience, specializing in: Internal Medicine, Emergency medicine, Aerospace medicine. Tel: 830 538-3550. Dr Neel further stated that he does use vitamins also, I just don't know the Dosages: Vit A, Zinc, Vit C, Vit D, Melatonin & Virgin Coconut oil 15cc 3X daily. Please forward to family, friend and others.

When I first started writing this article about Melatonin/Covid-19, it was with the intent of using melatonin as an aid in recovery from long-lasting effects of Covid-19 that were just beginning to be seen in people who had supposedly recovered from Covid-19 and I thought that at the rapid rate that the disease was expanding, this would soon be a health issue that would need to be dealt with in the near future and melatonin seemed ideal to the task. Shortly after I started writing, I came across Dr. Neel's reports and realized that melatonin would not only be useful in long-term Covid-19 recovery but was also likely to work rapidly at reversing the disease process.

In any case, the reason I started writing was for the long term effects that I felt certain would become a problem in short order and it appears that time has arrived where patients who have supposedly cleared from the infection are having longer term health effects and these effects are now being reported and written about. Here is such an article that describes these multiple health issues that are now cropping up months after patients have supposedly recovered.

https://www.mayoclinic.org/diseases-conditions/coronavirus/in-depth/coronavirus-long-term-effects/art-20490351

This problem is becoming so common that they even have names for it now such as "long haulers" or "post Covid-19 syndrome". In my opinion, melatonin is still relevant in trying to deal with these health issues which doctors have little experience dealing with, just as when Covid-19 first showed up, so if you are thinking they will be able to help with these symptoms, you may be very disappointed.

Keep your melatonin handy!

For anyone thinking the high melatonin dosage is crazy... you'll be fine!

Husband started with a sore throat late Friday night. I had him gargle with apple cider vinegar in water and we also took liposomal vitamin C, D3, echinacea, and Chanca Piedra. Applied some DoTerra OnGuard oil.

Saturday again with those things plus had him gargle with warm salt water, which he said helped.
Saturday night he ran fever so we slept in separate beds and I have tried keeping my distance and wearing a mask. Although probably not 100% of the time. Gave him baby aspirin.

Sunday we took the same things mentioned before and I added garlic for him. He has been sipping on water with lemon and Gaia herbs bronchial wellness tea as well as ginger tea. We scheduled to get tested. Rode in separate cars but tested together in the same room, at which time he had 100.4 fever.
He's positive. I'm negative.

Sunday 6pm 1st dosage of melatonin for us both. 20mg.
Took a second dosage at 1am. 20mg.
Another at 7am. 20mg.

I have been able to wake up a few times to go check on him. Tested his oxygen level and temperature. Normal.

I don't feel anymore sleepy than I do when I take 10mg. I had stopped talking melatonin last week because it's been giving me headaches. We had been taking it regularly. Natrol brand, 10mg time released. Husband had not stopped taking it. I currently feel just a light pressure (nothing terrible). Decided to drink some coffee and type this up.

I plan to continue 20 mg melatonin for us both at noon or 1pm today.
Oh! I've also been boiling water on the stove on and off all day with drops of Eucalyptus oil. We live in a pretty dry climate and with the heater running sinuses get really dry.

Art, I hope to keep updating. Let me know if you have any comments/ suggestions/ questions. Thanks for all the information you've provided!

Everyone is now aware of the fact that the president and his wife have Covid-19 and apparently there are several of his staff who also have it.

Trump always talked about how hydroxychloroquine was the solution to the problem, but he is not taking it! Nope, he's taking melatonin! ABC news just reported that.

Does anyone besides me find it odd that his administration never once mentioned that melatonin might be useful to fight Covid-19 and yet it is what they are giving him???

Art

This is the latest update from Dr. Neel in which he says melatonin is also showing efficacy against the Covid-19 Delta variant. He advises that he has had very good results using high dose melatonin, especially when applied at the first symptoms of Covid-19 infection, and reiterates that results have been seen quickly with the earliest application.

Here is a link to his update :

https://devinenews.com/dr-richard-neel-encourages-forget-about-sleep-read-the-research-on-the-anti-inflammatory-anti-oxidant-and-immunomodulatory-side-of-high-dose-melatonin/#more-25220

He also mentions again that he will talk with any and all doctors who would like more details on his high-dose melatonin protocol.

Art

Unfortunately, those side effects are not uncommon. These vaccines are still in the very early stages of trials so waiting it out but staying well with natural remedies is much preferred.

Just to give a quick update on my friend's friend with confirmed Covid-19 who is taking high dose melatonin (HDM). After starting melatonin, within 24 hours, she reported stoppage of pain in all joints as well as reduction of of her severe headache which she described as a 12 on a scale of 1 to 10, down to a 2.

By the end of the second day of treatment, she reported being symptom free. She said she still intends to continue HDM for another 2 to 3 weeks to try and prevent long term damage as well as Long Covid.

Unfortunately, my friend has herself gotten Covid-19 as confirmed by 3 rapid tests all confirming positive for Covid-19. She had given her melatonin to her friend so she is using Ivermectin which she reports is keeping her symptoms mild at this point, day 2. She said she will update me when she knows more.

Art

Hi Art -

Thanks for the latest Dr. Neel article on using high-dose melatonin for Covid.

Fortunately, most people have access to melatonin whereas other popular treatments are much harder to get for a lot of folks (e.g., ivermectin, hydroxychloroquine).

What a brave man this doctor is. Despite all of the research he provides to other professionals, he must be so disappointed when all he hears is "it isn't part of the protocol" meanwhile people continue to suffer and die needlessly.

It's also good to read Dr. Neel's comments regarding the Delta variant (which, I'm sure, will be replaced by the variant du jour any time now).

Kudos to all of the doctors who go beyond the call of duty to, firstly, do no harm, and, secondly, have the courage to follow their convictions despite hearing the popular excuse "it isn't hospital protocol" - these are the real doctors, the true heroes.

As you've pointed out previously, melatonin is used for so many other illnesses and it has a high safety profile.

I've stocked up - you never know when there will be shortages of things that actually work!

Thanks again.

Cheers,

Tessa

Thank you, Art, for this important and timely information about high dose melatonin. I was diagnosed with Covid the Tuesday before Thanksgiving and began your protocol of 80 mg/day in divided doses the following day. My symptoms (ongoing severe headache and other less painful symptoms) reduced very quickly. I had minor respiratory involvement which never fully developed.

My question is how long do I continue to use the high dosage? From reading through the information you provided, I'm thinking to reduce dosage and see if symptoms return or worsen? At first, I thought I should stay on it for a minimum of two months. Any clarification or thoughts will be appreciated.

Shout out to Earth Clinic for being Earth Clinic!!

I often read your posts & I must tell you that I am incredibly Grateful that you so generously share your Valuable information, research & expertise. Thank you So Very Much, Art♡

Hello Joseph,

Yes, Dr. Neel is being cautious with the higher dosing that they have used at The Doctors Hospital in Manila. They have gone as high as a starting dose of 200 mg/day in divided doses and then titrated up toward 600 to 900 mg/day in divided doses depending on the severity of the patient's condition.

Actually, Dr. Neel is taking a risk just giving his patients the 1 mg per kilogram of body weight that he has been using for over a year now as his starting point for his patients because if the FDA or AMA decided to make an example out of him, his long medical career could be ruined. He is a pioneer in this effort and was introduced to other doctor's at the virtual symposium they attended in January as the world's leading authority on the use of melatonin for Covid-19, so we are fortunate that he chose to take that risk in order to share his results with the world and I am grateful that he did. Manila has not yet completed their study in which they chose to only select patients who have Covid pneumonia, a tough study design that no other study group has chosen to try as these patients have a significantly higher mortality rate.

Unfortunately, Dr. Neel is pretty much being ignored by the scientific community and medical establishment despite his exceptional results using melatonin in his Covid-19 patients even though he has recently reported that melatonin is also effective against the Delta variant.

Art

This recent report (August 26,2020) of an 87 year old who was treated with HDM and treated early, survived with no complications!

Here is a link to the brief article:

https://devinenews.com/hooker-87-beats-covid/

Although it is just one case, 87 years old is a definite high risk case and he survived with High Dose Melatonin, along with vitamin D, zinc and vitamin C. Melatonin has shown synergy with these vitamins in recent studies. These four supplements are noted for having very good safety profiles and are all commonly available over the counter and are inexpensive. Simple, easy and effective and can be started earlier than the drugs being prescribed for Covid-19 in most cases.

This bodes well for the elderly!

Art

Nancy11,

This is going to be a long answer.

To briefly answer your question, yes, I would lean toward "melatonin only", at least until you find that your breathing difficulty has improved significantly back toward your normal. This should help allow your lungs to heal to the extent that melatonin is capable of doing.

Once and if you improve from the melatonin supplementation, then you can consider whether you want to add H2O2 to the mix. Melatonin is likely to work against H2O2 as it is a radical and melatonin neutralizes radicals and melatonin can enter any tissues in the body and is proven to significantly affect the lungs.

More on this below and a possible workaround.This is a tough question for me, because I look at H2O2 as a very potent oxidant that can potentially lead to excess oxidative stress and I see that as the reason it would very likely be effective at destroying SARS CoV-2 that exists in the lungs via inhalation of H2O2, but once the virus is destroyed in the lungs, do you really need to keep inhaling a potent oxidant (H2O2) into COPD lungs that already have elevated levels of H2O2 as shown in existing studies?

I know there is plenty of anecdotal evidence that suggests H2O2 inhalation may be beneficial for COPD and in one sense that seems likely as it will very likely kill bacteria in the lungs that may thrive in the lungs of people with COPD and help to feed the disease process.

On the other hand, studies have shown that exhaled H2O2 is elevated in people with stable COPD compared to controls and is almost 3 times higher in COPD patients whose condition is exacerbated as opposed to stable.

This data could mean that the body is able to produce enough H2O2 for COPD lungs on its own, or it may turn out that even though the body produces more H2O2 in the lungs as the disease severity increases, it is not able to produce enough to reach maximum efficacy.

I have not seen data to confirm that additional inhalation of H2O2 will be beneficial, though the anecdotal evidence suggests it may be.

So inhaling H2O2 will add even more H2O2 to the already elevated levels in patients lungs with COPD and this is where the anecdotal evidence and the science seem to part ways as the science so far does not seem to support the inhalation of H2O2 in patients with COPD.

Oxidative stress is elevated in COPD as is inflammation and these two work together in a vicious cycle to increase each other as elevated oxidative stress increases inflammatory cytokines and mediators which also creates more oxidative stress ultimately creating an environment that is conducive to disease progression.

If you could look inside your lungs to see how they are reacting to inhaled H2O2, that would be very useful, but that is not possible and with no practical way to know if there is enough or too much H2O2 in the lungs, the melatonin may help with this aspect of H2O2 inhalation.

Melatonin, on the other hand, has many studies that show that it is beneficial for COPD patients and two of the effective mechanisms of action are its potent radical scavenging and very potent antioxidant activities as well as its inhibition of inflammatory cytokines which may have the potential to break that vicious cycle that can be quite active in COPD.

Another consideration is knowing that melatonin level drops when the disease is in an exacerbated state, exactly when more melatonin would likely be needed! Melatonin levels also decline with age.

Melatonin is the most potent antioxidant in the human body because it elevates the gene expression Superoxide Dismutase (SOD), Glutathione Peroxidase (GPx), Glucose-6- Phosphate Dehydrogenase (G6PD) and Catalase (CAT) while increasing Glutathione. Melatonin doesn't stop there though. It is also a potent scavenger of Peroxynitrite (ONOO) which is elevated in COPD and has negative effects, it scavenges Reactive Oxygen Species (ROS) / Hydroxyl Radicals, Reactive Nitrogen Species and H2O2 which are all mostly elevated and damaging in COPD and help extend disease progression.

Melatonin is also able to do something that other antioxidants like vitamin C and E can't.

Vitamins C and E can each neutralize one oxygen radical while melatonin can neutralize as many as 10 oxygen radicals because each time it reduces one oxygen radical, melatonin becomes a different metabolite of itself and each of these metabolites can in turn neutralize another oxygen radical.

Add in the antiinflammatory qualities of melatonin and it is a potent molecule to use against Covid-19 and COPD!So given all of the above, for myself, if I wanted to try one or both of these and if I believed they both had potential to help people with COPD, I would discuss it with my doctor to see if he thought that either one or both might be helpful for me and would be compatible with my current medications. If he or she approved the use of both, then I would consider an appropriate plan of attack.

I suggest that anyone reading this also get their doctors approval before trying to implement such a regimen.

Given that melatonin is likely to work against H2O2 by neutralizing it directly or indirectly through the upregulation of Catalase or other antioxidants which will also neutralize it, I might consider a rotating approach where I use one for a day or two followed by using the other for a day a day or two. This could possibly allow the H2O2 to work while the next phase allows melatonin to give the lungs a break and neutralize the elevated radical levels in the lungs as well as lower the elevated inflammatory levels in the lungs.

H2O2 is highly likely to do some damage in the lungs and the idea being that melatonin may nullify or repair some of this damage while helping to work against COPD through its known multiple actions against COPD.

So that is my idea of how I might use these two substances under my doctor's supervision based on my experience with both substances and the available studies I was able to find. I did not include any study links in this post because it is long enough already.

Art

Below is a link to a new study (June 2022) that suggests that melatonin may also offer brain-protective effects from Covid-19 and binds to ACE2 receptors on endothelial cells:

https://link.springer.com/article/10.1007/s00018-022-04390-3

Here is a relevant quote from the study:

>>> ' In conclusion, we disclosed ACE2 as a new binding target of melatonin, which leads to allosteric negative modulation of the spike/ACE2 interaction. This effect on the SARS-CoV-2 entry receptor function of ACE2, combined with the inhibition of NFKB expression and endogenous ACE2 expression in endothelial cells, is most likely the predominant mechanism for impaired SARS-CoV-2 brain invasion by melatonin and its derivatives. ' <<<

An important point of this study is that melatonin binds to ACE2 receptors interfering with the ability of the SARS CoV-2 virus to dock on ACE2 receptors and melatonin does this without serious side effects.

Art

Hi J.

In order to be sure this was Covid-19 or not, I have scheduled a test for tomorrow morning. Even if it turns out not to be Covid, that means it is most likely the flu and I have never used anything on the flu that reversed its course so dramatically in 12 hours, not even colloidal silver via inhalation and orally simultaneously! So I'll take that! In any case, the nurse told me it would take about 2 days to get the results back and I will update this thread once I have those results later this week.

Regarding continuing the melatonin series on EC, I have one post that will be going up a little later and that will be the end of the melatonin series on EC. I have already covered Covid-19, memory, CVD which is actually a group of diseases, sleep, oral lichen planus, gum disease, ulcerative colitis, and the next post that will be coming out in the near future and that will be it for melatonin.

Art

Thanks Mama to Many for your update.

Not only was the information on what you and your family took very valuable in itself, but I appreciate how you mention people shouldn't feel guilty for getting ill - regardless of what preventatives they may take. No one benefits from the shaming/blaming game. Thank you for the compassion you always show to others.

And I'm so very happy that your family is feeling better!

Take care,

Tessa (from cold Canada)

Here is the latest update from Dr. Neel who has now treated over 1,000 Covid-19 patients with high dose melatonin (HDM) with only a handful of patients needing to be admitted to the hospital at all!

Generally, he uses a dose of 1 mg per kilogram of body weight, but other doctors are now reporting going as high as 6x higher than Dr. Neel, by using up to 6 mg per kilogram of bodyweight! Overall, this is the best update yet and is quite informative because Dr. Neel attended a symposium of melatonin researchers and doctors who shared their information that they have gathered over time in the treatment of their patients with HDM. Even Dr. Castillo who is involved in the Manila study of HDM in Covid-19 patients who also have pneumonia. His team is doing the world's first randomized, placebo controlled, double blind study of HDM to treat Covid-19 patients. Dr. Reiter also spoke at the symposium as did Dr. Brown of Canada talked about intravenous melatonin because oral melatonin is known to be absorbed at only 3% to 15% of the dose taken while intravenous melatonin has much higher bioavailability. Dr. Castillo also mentioned a "maintenance dose" which many people are wondering about. The general consensus of the doctors who spoke at the symposium was 20 mg /day.

There was more to the update, but this was clearly the most informative and exciting update yet! Here is a link to the article :

https://devinenews.com/dr-neel-introduced-as-worlds-leading-expert-in-treating-covid-19-with-melatonin-clinically/#more-21819

Art

Hi Kristine,

I have answered this questions a few times and that answer would be in the link to the original post in my reply to you.

Melatonin is known for what is often referred to as the "melatonin hangover" which I assume you are referring to. For many people, this issue diminishes with regular use as the body adjusts to increased melatonin.

As far as I know, Dr. Neel only prescribes melatonin for Covid-19 when you get symptoms and test positive. Under those circumstances he starts his patients at 1 mg per kilogram of body weight. So essentially he does not give it to you until he knows you are sick. Once you are sick with Covid-19, you shouldn't be going anywhere outside of your home as you are contagious. That means you should be spending the majority of your time at home in bed resting and good sleep with Covid-19 is rare. So imo, actually getting more restful sleep is a good thing and melatonin is known for helping to get people to REM sleep where your body is able to do more repair than in non REM sleep.

Lastly, Covid-19 is deadly in some people, so would I really be worried about if I felt tired or not in order to take melatonin? My answer is no and that should be the least of my worries with a known deadly disease! Keep in mind that melatonin has a better safety profile than any drug currently being used to treat Covid-19 and melatonin has shown in one study to improve outcomes for patients on a ventilator. No other Covid-19 specific drug that I am aware of can do that!

So for people who are "very worried" about feeling tired if they take melatonin for Covid-19, perhaps the answer is to skip melatonin and go with something like Hydroxychloroquine, Remdesivir or Favipiravir which all do poorly in late stage Covid-19 disease and nobody is really even talking about these drugs any more for Covid-19 because the available studies and results for them are nothing to get excited about.

Art

Mary Lou,

I think that most of the residual problems that you're having after your COVID-19 infection are perhaps mainly due to the inflammation caused by existing residual virus issues(acting in the intestines) that can always occur whenever you recover from any viral infection.Don't forget that most virus have the ability to hide from the immune system(eg Herpes virus, Epstein Barr) and COVID-19 is really no different.

In all the recent research that I've read on COVID-19, it is a fact that ALL cells in the human body have special inflammation ACE-2 receptors. And since the COVID-19 virus attaches to the cellular ACE-2 receptors and disrupts it, that therefore means that ANY tissue or organ can be seriously affected by inflammation whenever you are infected by COVID-19. I've also read much research that confirms that COVID-19 inflammation can cause cytokine storms, heart mycarditis, thick blood, arterial build up and occlusion(arterial blockages), pneumonia, kidney/liver/pancreas problems as well as causing problems in the intestines.

You can perhaps use a three pronged strategy against COVID-19 by supplementing the following:

1. Serious immune boosting all-round anti-viral neutraceuticals like Ted's lysine + Vitamin C protocol or quercetin + resveratrol, or niacinamide. These are just a few of my favorites.

2. Supplement neutraceuticals that directly attack the virus by stripping the oily outer coat from lipid coated viruses(like COVID-19), which then exposes the the virus protein as a foreign protein body, which the immune system then identifies as enemy non-host protein and so it is rapidly destroyed and removed by the immune system. Neutraceuticals that can strip the oily coat of the virus are: Virgin Coconut Oil(3 tablespoons a day), simple aspirin(taken 4 times a day at 3 hour intervals outside meals) and BHT(up to 500 mgs 3 times a day outside meals).There is also alot of conflicting research evidence on BHT mainly caused by all the "spoiler research" on BHT that has been put out by Big Pharma. The best and most honest research and recommendations I've found for supplementing BHT comes from Dr Steve Fowkes, an independent and honest researcher, who has been investigating BHT's beneficial anti-viral properties for over 20 years. See his free ebook -- called The BHT Book -- for more info on BHT.

3. Take supplements that act to suppress the inflammation caused by the out of control ACE-2 receptors. Tumeric and melatonin are perhaps the best supplements to take for this -- and you are already taking them.

To further improve your residual intestinal problems(severe diarrhea) I would just do one round of Milk of Magnesia at the normal, recommended laxative dose. Make sure you do this at the weekend so you are always near a toilet. After your intestines have been cleared out by MoM also make sure that you re-mineralize the blood electrolytes by taking the appropriate minerals. MoM causes the laxative or diarrhea effect because of its high alkalinity(pH 10). At that pH MoM will also kill any pathogens(incl viruses) or parasites in your intestines. By the way, taking MoM this way is also one of Ted from Bangkok's anti-pathogen remedies for problems in the intestines.

And after you have cleared out your intestines with MoM, you should continue your current anti-COVID protocol until you are fully recovered.

To further update, I talked to my friend this morning and she said she still has very mild symptoms with the use of Ivermectin.

She told me she had just talked to her friend and said she feels great on melatonin with no further symptoms and said she intends to continue for the 2 to 3 weeks to try and avoid Long Covid and long term damage from the virus.

My friend told me that she is going to replenish her supply of melatonin as she gave her current supply to her friend. She also said that if she gets Covid-19 again, she plans to use melatonin instead of Ivermectin. She said her doctor will write the script, but the local supplier she was getting it from is now charging a lot more for Ivermectin so she is going to switch to melatonin since it is very inexpensive and available everywhere.

So good news for both my friend and her friend!

Art

Hi Tessa,

Very well said! It seems to make plenty of sense to keep melatonin on hand in case the need ever arises.

I am still at 106+ mg/night of melatonin for very close to a year now.

Art

This isn't a vaccine, it's incredibly dangerous, read vayers report. You cannot compare this to the polio vaccine.

Thank you for sharing, Art. It is pleasing to learn that you recovered so quickly from your ailment. Also, it would be nice to learn about your various observations regarding melatonin. Rather than being tiresome, the subject matter of melatonin is quite interesting.

Sincerely,

J.

Here is the update I promised regarding my Covid-19 test.

So I went and got tested yesterday morning for Covid-19 and this morning the doctor's office told me I tested negative for Covid-19!

Aside from not having Covid-19, I am happy about this result because it still leaves open the possibility that melatonin can act as a Covid-19 preventative which will be very important in the future if the virus mutates enough to make the vaccines ineffective and it also means that melatonin can act against the flu very rapidly, or at least it did in my case for whatever flu this was. The flu normally drags on for me for up to a month, so hopefully melatonin will work this well everytime I have the flu! The doctor's office said that although I do not have to quarantine at home, I should still avoid being around other people for awhile because they are getting more patients with flu now.

Art

Wow, Jacob, that is amazing! I am very glad that your recovery was so quick and smooth!

Thank you for coming back and giving this update as it is useful for any of the members who may get Covid.

Your results pretty much mirror what Dr. Neel has seen in his over 1,000 Covid-19 patients. Once full dosing is initiated, improvements are generally seen to begin the very next day. In the symposium he recently attended about using melatonin as a treatment for Covid-19, the doctors who attended were asked what if any dose may act as a preventative. Their answer was that is not yet known about melatonin, but they felt that if there is a dose that may act to prevent Covid-19 from getting started, it would be 20mg minimum.

Thank you again for your update, Jacob!

Art

Very recently I found out that some 10 mg melatonin capsules also contain vitamin B6. This will not work for high dose melatonin (HDM) treatment as it can deliver to much B6 and this can be unsafe and unhealthful to take in that much B6 everyday! The B6 is added for the purpose of increasing the absorption of melatonin. Stay away from these types of melatonin that contain extra B6 as they should not be used for HDM.

Art

Hi Lynn,

Thank you for saying so!

Yes, the two should work well together and I believe there is a relatively new and popular protocol on the internet that uses both. When you look at what the virus does once it enters your system and compare what melatonin does in your system, you realize just how appropriate melatonin is to counter many of the moves of the virus.

Since you are newly diagnosed, it seems useful for you to also incorporate Xlear nasal spray into your plan of attack as it works fast and directly with the virus to lessen symptoms and length of illness as described in studies. I wrote about that here:

https://www.earthclinic.com/xlear-for-covid-recovery.html

These three together should be quite a potent combination against Covid-19 and should speed the recovery process while very greatly lessening the chance for "long hauler" symptoms.

I hope you have a speedy recovery!

Art

Hi Roxie,

Yes, they are compatible and in fact there is one protocol that I have seen on the internet that uses both, but usually if they are both used, the melatonin dose is taken way down to a level that is similar to the dose used in a melatonin Covid-19 randomized controlled trial that used just 9 mg of melatonin daily in 3 divided doses to very good effect. I posted that study on EC, but here it is again :

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220995/

Here is what this study concluded regarding the use of just 9 mg of melatonin as an adjunctive treatment for Covid-19. This is a direct quote from the study :

>>> ' To conclude, the results from this study revealed the efficacy of oral melatonin as an adjuvant therapy added to the standard of care compared with standard of care alone in patients hospitalized with mild to moderate COVID-19. Improving respiratory symptoms, time of patient discharge and return to baseline health are in favor of the efficacy of this adjuvant medication in mitigating this infectious disease. Considering the high performance of melatonin as an inexpensive, affordable, highly safe to human and readily available medication, it is suggested that it alone or in combination would be further investigated in COVID-19 prophylaxis in future studies. ' <<<

So as you can see melatonin is quite useful at fighting Covid-19 even at a low dose, but not as effective as high dose melatonin such as Dr. Neel has used effectively in over 1000 Covid-19 patients.

Art

Two young healthy active people from my family got bad side effects from the vaccine. One had a seizure and the other immediately started having heart problems. The one that had a seizure and can't get in to see a neurologist anytime soon because they are so booked up because of all the neurology problems from the vaccine. Melatonin is probably helpful, but consider having BHT on hand to take at the first sign of symptoms. Look up BHT for covid-19 here on earthclinic.

Please look into virus shedding from vaccinated people. I've had 2 nosebleeds myself after being near someone recently vaccinated. I have NEVER in my 57 years of life had a nosebleed. It's very concerning.

Waneta,

When I say some people can't tolerate melatonin, I mean just that. They can't tolerate for different reasons, but you are a prime example because you feel the melatonin hangover the next day which means you will feel sleepy the next day after taking melatonin the night before. If this effect is too strong in you to be able to function properly, then you do not tolerate melatonin.

I had the same issue as you when I started taking melatonin, but with time my body adjusted and I no longer feel the melatonin hangover, but some people never seem to adjust and have to stop taking it.

For Covid-19, next day tiredness may be a problem you can temporarily live with until you are well, as being tired may help you get to deep REM sleep where your body heals well.

Art

Hi Karen!

First and very importantly, thank you for coming back to EC to share with us how melatonin worked for you! I am very happy to hear that high dose melatonin(HDM) worked for you so well and quickly against Covid-19!

Can you give a little more specific information while it is still pretty fresh in your mind?

1. How long after your first symptoms did you start melatonin?

2. How long after your first dose of HDM did your symptoms start to improve?

3. How long did your symptoms last after you started HDM?

4. Is there any other information related to Covid-19 and melatonin you feel is worth sharing with our community?

To answer your question about HDM, I can only tell you what my plan is if I ever get Covid-19. I plan to start at the first symptom with or without a confirmed positive test for Covid-19 because HDM has also shown the potential to help with the flu. I will start at Dr. Neel's last dosing update of 1 mg of melatonin for every kilogram of body weight. So for a person who weighs 176 pounds or 80 kilos, the HDM dose would be 80 mg of melatonin per day. It sounds like patients who are showing severe symptoms or are fairly late stage, Dr. Neel might go higher on the dosing on an individual basis.

I will stay at 1 mg per kilogram of body weight / per day, well beyond the point of no symptoms because being symptom free does not guarantee that you are also virus free. The other reason I will do this is because the latest Covid-19 research is showing that people are developing Covid-19 complications months after supposedly being Covid-19 free and symptom free. The latest after effect related to Covid-19 in men is that of erectile dysfunction. Just a month or so ago it was found that 1 in 5 patients will develop a neuro conditions such as depression, anxiety or insomnia among others. The post Covid-19 issues regarding the lungs and heart are also being seen and can be life long.

In my opinion, this is where the body and organ protective effects of melatonin can really shine beyond just its ability to greatly lessen the effects and symptoms of Covid-19. The known effects of melatonin in humans suggest that melatonin may be able to mitigate some, if not all of the after effects of Covid-19 and possibly prevent these unwanted effects which show the potential to become life long health issues. So for me, I plan to take HDM for at least two months after being symptom free, unless I develop a problem taking HDM, in which case I will stop HDM if I have a problem with it. This two month period of HDM is for the purpose of possibly preventing the potential side effects of Covid-19.

Continued better health to you, Karen, and I look forward to your update!

Art

Here is the latest very promising report on Dr. Neels melatonin / Covid-19 protocol as used in a Texas convalescent facility. As many of you already know, these convalescent facilities are fairing very poorly with many patient deaths being the norm! This convalescent facility didn't waste anytime implementing Dr. Neels protocol once they had their first two cases die from Covid-19. They started using HDM right away and had no more deaths from Covid-19! One patient died afterward from another health issue. This is very important because this is a senior population with health issues and age that put them at increased risk of succumbing to Covid-19.The rest lived.

Here is a link to the latest article :

https://devinenews.com/lytle-area-facility-fights-back-quickly-as-covid-outbreak-strikes/

Art

Dear Art,

I really appreciate this post on Melatonin, H202 and COPD. It is timely for me. We are getting ready to move my mother in law into our home and she has COPD, in addition to other health problems.

By the way, I continue to take Melatonin at night for sleep and it has definitely helped me!

Thank you!

~Mama to Many~

Dr. Neel has treated over 400 Covid-19 patients now, as of July 22, 2020!

Since his patient load has increased very considerably, so has his knowledge and understanding of the use of HDM (High Dose Melatonin) in Covid-19 patients. This seems like one of his most informative updates so far!

Dr. Neel is now seeing patients who are in multiple higher risk categories and treating some of them is no walk in the park. Dr Neel is now using even higher doses of melatonin in these harder to treat patients at dosing that is closer to what Dr. Shallenberger uses in almost all of his non cancer patients and similar to what Dr. Reiter has used in some of his studies. Dr. Shallenberger uses much higher dosing in his cancer patients though.

Dr. Neel also mentions that he is now seeing many more young patients than in the previous 3 months. He also mentions that people with asthma are having a harder time with Covid-19 than his patients who don't have asthma. He is also seeing more young patients who are developing gastrointestinal issues. He does not mention any deaths in this latest update.

He also mentions that he is seeing at least one strain of virus that seems to be more virulent. The information he includes with this latest update does not seem to bode too well for the supposedly soon to be available vaccinations, if the virus is mutating significantly. Here is the link to this latest update:

Art

Karen S.,

Dr. Neel has never mentioned a preventative dose because melatonin is not likely to prevent Covid-19, only lessen the symptoms and help the body fight the virus off on its own without the deadly complications often seen in Covid-19 patients. Dr. Neel has only given melatonin to patients who have shown symptoms and tested positive for Covid-19 and these patients have turned their symptoms around in one day after starting HDM.

Many people have reported next morning drowsiness with melatonin, myself included. I don't necessarily consider that a negative for someone with Covid-19 as rest is likely good for someone with Covid-19 to help maintain a more effective immune system. Dr. Neel is currently recommending 1 milligram of melatonin for every kilogram that the patient weighs. So if a patient weighs 80 kilograms, then they would take 80 milligrams of melatonin.

That is the advice he is giving to other doctors who are wanting to use melatonin on their Covid-19 patients.

Art

Your story is one of the extreme few. People still need to get vaccinated. Statistics show that uneducated, poor people who are not vaccinated are the most likely to end up being hospitalized - taxing the medical system. The country is wearing thin on non-patriotic selfish behaviors. Imagine during the polio plague if vaccination would have been so politicized? We would still see a great many in wheelchairs. Now, we just see data on death. Get vaccinated now and save yourself as well as the United States.

Hi Deb,

Yes, when I first started testing melatonin years ago, I started low at 5 mg per night and slowly worked my way up to 70 mg/day. I consider this a reasonable method for me to test melatonin as some people do not tolerate melatonin and it seems reasonable to me to start very low to first find out what my tolerance for melatonin is because if I don't tolerate melatonin, I wouldn't want to find that out at a high dose that might cause me problems. By testing this way I have been able to work myself up to a dose of 180 mg temporarily to be sure I could tolerate that dose that Dr. Shallenberger uses in his patients. I have not gone anywhere near his higher dosing that he uses in his cancer patients, but cancer is a very serious disease that apparently requires this type of dosing that Dr. Shallenberger is using.

Art

Hi again, BellaPaolina,

Powder is fine and it works.

As regards Covid-19, Dr. Neel's preference is sublingual tablets, but I think his main reason was he wanted to have the option to give these to Covid-19 patients who were already on a ventilator since they would not be able to swallow pills or capsules. Previously I mentioned that I did not think there was much difference between the typical sublingual tablets and regular tablets, but I think I may have been wrong on that point and now think the sublingual versions may have a slight edge over regular capsules and tablets, but I have not yet seen any studies one way or the other.

The untested method I use on flights is double masking with a filter insert and a face shield with a closed top above the eyes. I also use XLEAR Nasal Spray which I have previously written about in December to fight Covid infection and speed the recovery process while also reducing symptom severity. Here is a link to that article :

https://www.earthclinic.com/xlear-for-covid-recovery.html

It may seem like overkill for jet flights, but the virus can and does travel in the air, and on a jet, the air is constantly recirculated for the flight so you are at a relatively high exposure level if there is an asymptomatic virus carrier on the flight. Airlines are starting to move toward virus testing at an additional cost with results in minutes and this could make flying safer. At a bare minimum, I would expect it to lower viral particle exposure and lower particle exposure has shown reduced severity of Covid -19 if you get it. High viral load equates to more severe symptoms. I'm not saying or recommending that anyone should do what I do, I'm just answering your question about what I do. I also carry a small enough hand sanitizer to meet airline limitations and I do carry surgical gloves in my pocket if for handling anything in an airport or jet. Between that, the Xlear Nasal Spray and melatonin, I would say that is about as safe as I can get on a flight, imo.

Art

Hi Bill,

Unfortunately Dr. Neel's work with HDM is largely ignored by the FDA, doctors, main stream media and scientists in general. There are a few studies showing the safety of melatonin at high dose for years, but my experience is that some people simply do not tolerate melatonin very well, so as far ultra high dosing, I would reserve that for stage 4 cancers and other serious diseases that move relatively quickly like ALS.

One thing that Dr. Neel's work seems to show is that melatonin also seems to prevent some of the serious after effects of Covid-19 that are showing up in people months after supposedly being clear of the virus. This is something that apparently "standard treatment" can not claim.

I still feel that HDM and Xlear Nasal Spray are a very good combination to work against Covid-19 in a timely manner while minimizing symptoms very significantly and shortening the time to being symptom free. Dr. Neel said that only a handful of his over 1,000 HDM patients even needed to go to the hospital. The great majority have treated themselves at home with Dr. Neel's guidance.

They are even thinking that melatonin may have preventative effects at a high enough dose. In my current melatonin test I have been taking 106 mg per night for over 3 1/2 months with no issues that I am aware of, but I knew from previous testing that I tolerated HDM fairly well.

On a related note, the Manila trial of HDM seems like it should be close to completion, but they took longer to recruit patients than anticipated and consequently their results have been delayed. I am anxiously awaiting their results!

Art

Today (10/19/2020) Dr. Mercola posted an article essentially confirming what we here on EC have known for month about high dose melatonin. Hopefully an article from Dr. Mercola who has a good sized following will get even more exposure of melatonin for Covid-19!

Here is a link to his article:

Art

Trump did finish a two-week trial of hydroxychloroquine in May, probably as a prophylactic because it showed promising results in early studies. Of course we now are aware of more possible therapeutics such as melatonin and vitamin D due to more research. But he's not advocating the use of a particular drug now, after HCQ has become politicized.

Thankyou Art, for your well-written article. I tested positive yesterday and started Ivermectin. Someone told me that melatonin and Ivermectin are similar so I wonder if I should take both??

Hello Sarah from Florida:

Regarding: How to avoid drowsiness when taking melatonin: "Stay active". Another thing to do is: Make sure the brand and type of melatonin you buy does not have other ingredients to help sleep in it. An example is some melatonin companies add Lemon balm to help melatonin in its sleep work.

For some people, just staying active will chase away any drowsiness. When I had that unbelievable cold or covid condition, I took about 25mgs of melatonin every four hours without any daytime drowsiness. I took it like that for three days. I was taking care of my Aunt and she can be a hand full. Truthfully she is the busy one. When my turn comes to stay with her, I just keep an eye on her and am more of a nurse and cook than anything else. Even with talking melatonin all day, I did not go to sleep until I relaxed to go to sleep, and that usually lasted 2 hours straight, the rest of the night my sleep was on and off, and finally wide awake around 5 a.m.

So check the label and make sure there is no other sleep ingredient in it.

HisJewel

Hi Carol,

I use 10 and 12 mg melatonin in three forms.

One is a direct release 10 mg capsule generic.

One is a 10 mg delayed release tablet that also contains vitamin B-6 at 10 mg that I got at Sam's Club.

One is a fast dissolve tablet that I let dissolve in my mouth to try and get the oral benefits of melatonin.

There are 60 mg capsules also available from online suppliers. Dr. Shallenberger recommends these to his patients and uses them himself. The 60 mg capsules are generally a bit more expensive that the 10 mg capsules and I will eventually test the 60 mg capsules myself when I settle on a final dose. I am currently using the lower dose capsules for a total of 106 mg per night for 5 1/2 months now.

Art

This is about clearing your air passages. I bought a nebulizer a year ago. People I know said they got a flu shot but still got the flu. I never got a flu shot but never got very sick. I used peppermint oil and other things. When I moved to my sister's house temporarily, just before the lockdown, she would not allow me to use peppermint oil in an infuser. So I bought a nebulizer, which I have been using with peroxide or saline or colloidal silver.

A few times a day if I get sinus problems. Every time I get home after a trip to the grocery store. I used it on my cat for about 30 seconds and his sneezing stopped the next day. This is all in the past year. I mix distilled water with a little salt or peroxide and add a few drops of silver. It keeps mucus down and clears bacteria and I can breathe well all day.

M to M,

I'm glad that you and your family had a relatively easy go of Covid-19!

To be clear on Dr. Neel's dosing schedule, it is ""1 mg of melatonin per kilogram of body weight"", not 1 gm.

Art

Hi Lynn,

Some side effects of melatonin that I am aware of are diarrhea/nausea, but there is often a delay to get to diarrhea that can vary from person to person to as little as a few days or as much as a few weeks. Other side effects are sleeplessness, vivid dreams, nightmares, daytime sleepiness which usually diminishes with daily use over time. Headache is another symptom that sometimes also goes away with daily use as the body adjusts to increased melatonin levels. Dizziness is another which for me was transient and went away completely with daily use. There are others, but these are the main ones that I am aware of. In studies, scientists and doctors consider these to be minor side effects and generally rate melatonin to have minor side effects and a very good safety profile.

I still feel that even though melatonin has a very good safety profile, I believe that some people are not able to tolerate it and should avoid using it, but the great majority of people are able to tolerate and use melatonin regularly.

Art

GertJr,

I'm not a doctor so I can't tell anyone else what to do or take.

Dr. Neel is recommending to other doctors and his patients, 1 mg of melatonin for each kilogram of body weight. If she weighs 105 lbs, that is equivalent to just under 48 kilos.

For myself, I would start at the first symptom and stop if the test comes back negative, but I am not recommending that anyone do what I do.

Art

This new study abstract goes a very long way in confirming the value of melatonin in Covid-19 patients who receive melatonin after intubation. It shows that melatonin applied after intubation is significantly associated with patient survival. This is very good news because it shows that even when melatonin is applied late in the disease process, it can be effective. Dr. Neel has shown in over 400 patients that early treatment with melatonin can resolve the disease process fairly quickly. So this piece of the puzzle is quite useful in further showing the effectiveness of melatonin for Covid-19!

https://pubmed.ncbi.nlm.nih.gov/33083812

The full study is not available yet.

Art

Considering the fact that the media turned his statement about Hydroxy into a political debate, I doubt that he would ever admit to anything he was taking. Here, a local doctor put all of his nursing home patients on Hydroxy (after a resident was diagnosed and passed away), and no one else at the facility caught Covid. I hated that anything was rejected - especially when no one could offer anything else. It's a 60 year old drug that is safe. Just my opinion.

Art,

Thank you for your reply.

I'm on day 9 of the virus and was just able to start Melatonin the evening of Day 7. I'm glad there was no noticeable difference using sublingual Melatonin as I couldn't find any that didn't have a lot of additives.

I used the Vitamin C protocol from another page on Earth Clinic of 1000 mg every hour, with Zinc, Quercetin, and then added D two days ago. Also, few other supplements- some of which are listed in my previous post.

I had about 3 days of very bad flu-like symptoms that changed to mild sinus congestion and head cold.

Right now (day 9) I feel pretty good, (actually almost normal) except for being extremely tired and feeling very weak.

I plan on retesting the first of October and will remain in self-quarantine until then.

Can you suggest how long to continue the Vitamin C and Melatonin protocols? Today I reduced the Vitamin C to every 2 hours.

Also, I am having the best nights sleep I've had in a long, long time!

In this latest update from Dr. Neel, he mentions that although the amount of new cases in his area of Texas have slowed a bit, the current strain affecting his area is definitely more difficult to treat than the previous strain he was working against. He has shown a willingness to raise the melatonin dosing level to help deal with this current strain because with this strain it has taken 3 days to start to see improvement whereas with the previous strain he was seeing improvement in just one day.

One thing he didn't mention is the number of patients he has treated as of today(8/26/2020). The last time he mentioned the number, he said over 400 patients treated. He still not has reported any deaths as of this update. Here is a link to the update:

https://devinenews.com/masks-to-melatonin-how-it-works-why-it-works/

Art

Below is a link to an article about a 4 year old boy in Texas who got sick shortly after his father tested positive for Covid-19.

Of note related to this story is that 4 to 7 year olds are at or very near the peak of natural melatonin levels seen in humans suggesting that melatonin can not prevent infection, but it can apparently reverse it in short order based on this and many other reports! This could be useful information for all of those people who have kids or grandkids! Here is a link to that article :

https://devinenews.com/local-4-year-old-battles-103-9-fever-days-after-dad-tests-positive-for-covid-19/

Art