Health Benefits

Xlear Xylitol and Grapefruit Nasal Spray for COVID-19 Recovery

| Modified on Feb 27, 2024
Nasal Spray for COVID-19 Recovery and Prevention.

by Art Solbrig
December 2, 2020

An Important New Covid-19 Study And a Specific Nasal Spray For Adjunctive Treatment of Covid-19 to Speed Recovery!

Previously on EC, I have mentioned using a nasal spray called "XLEAR" as an excellent nasal spray to help treat sinus infections and nasal issues in general. This product contains xylitol and grapefruit seed extract, which can kill certain bacteria, viruses, and both have biofilm busting qualities, all contributing to this nasal spray's effectiveness.

This new study also suggests that XLEAR may help treat an existing Covid-19 infection as an adjunctive treatment that shows potential to speed the recovery process, which could be useful and especially if you have other health issues which may be exacerbated by Covid-19 as lessening the duration of Covid-19 infection may help reduce the potential for worsening of the existing health condition.

Just thinking aloud here, but I wonder if using Xlear before going into a crowded area might be useful??? I have used colloidal silver in this way previously, but Xlear is easier for most people to get and is reasonably priced plus you know what you are getting. When I use the colloidal silver, I just put it in a two-ounce spray bottle and spray generously into each nostril while inhaling, and I suspect I could do similarly with the Xlear product.

Here is a link to the product:

Xlear spray is also available at CVS and most pharmacies. You want the product that contains both "grapefruit seed extract and xylitol."

The study mentions that Xlear has shown antibacterial and antiviral properties, which potentially include SARS CoV-2. In Covid-19 patients, Xlear was reported to result in rapid clinical improvement and shorten time to negativization on repeat intranasal swab test via PCR.

The clinical reports also lists how the nasal spray was implemented and the frequency of use. This study is very interesting and suggests a new and novel use for Xlear as an effective adjunctive treatment for Covid-19.


5 User Reviews

Posted by AndiSho (Mannheim, Germany) on 04/22/2023

I found the best explanation of its working principle by its developer there:
Corona-Spray Xlear Comensability (1) Comments - Xylitol Nasal Spray Prevents SARS-CoV-2 Infection

Everything except Glycerin / Glycerol is inhalable, since we buy Grapeseed Extract solved in Glycerine, do NOT inhale this component.

Also, you can add some NaHClO from dental supplies (3%) pleas do not go above 800ppm 1.5ml for 70kg standard lungs per session without knowing what to do (which is dose finding: mindfully watch free breathability or state-as-is while ill before, while and after some inhalation session with well defined concentration and amount of ml.
(Even better is halving the dose and letting inhaler run only while breathing in. Pari has a vent for this you can clamp under the inhaler heads, gets air pressure only while pressing a vent knob.)

We DIY a "base solution" of 9% xylitol, 0.15% iota-carrageenan and ca. 1% Dead Sea or stone salt we dissolve.
Dissolving iota carrageenan without clumps is as difficult as clump free pudding.
(Use a very fine sieve, place 0,45g powder / 300ml water on it and knock it gently on rim of the glass while stirring (we use magnet striker). As a sieve, we use Tupper coffee filtre (Melitta gold filter for 1 cup), or a segment of stockings, pulled over a pipe (or ring from small baking tin), have to try this as the very fine metal coffee filter of pitch 0.1mm is rare.)

The Mg++ or Ca++ in the mentioned salts do physically "harden" the mucosa, make it less penetrable for germs and prohibit aerosol formation quite good for 6 hours.
As a pharmacy, you can also do it as in the publication below, and mix mainly NaCl and some CaCl2.
Corona-Nasenspray CaCl2 Anti-SuperSpreading A New Natural Defense Against Airborne Pathogens

You can also find publications and a great relief by inhaling

- chromolynium acid (3 Puffs from nasal sprays, dito for sprays)
- azelastine
- CPM (antiallergic also)
- Hyalurone ans pathenole (is panthenole anti-oxidative? then inhale time-shifted from oxidants like NaHClO or H2O2 or NO in clinic (respirators have NO generators, let them run!)

Not tested, as I needed a lung compatible solvent, do not know if liposomal solving in phospholipides will do:
- progesterone
- lvermectine
- NicIosamide

I do not know is grape seed extract as powder without glycerine could be inhaled. Probably.
I try to be very precise here. When I say glycerine is not inhalable, as it irritates the alveoli, this may not be true for eCigarette smokers, as they are used to it, or Polysorbate (Macrogol). But: are they;)?

Also, it may be depending on the source of the glycerine, crude oil or cheap plant oil may be equally bad, and it could be that a nice bio plant oil is not irritating, but I can not answer this one.

Replied by Alex
(Thessaloniki - Greece)

About your last paragraph. Every oil if good or bad quality can cause lipidpneumonia if inhaled. Glycerin is not an oil.

Xlear Nasal Spray
Posted by Nathan (UT) on 02/10/2021

I am surprised that you have not mentioned the Xlear nasal spray in your natural solutions to covid19. Been on the market for decades in the natural retailers, have known it blocks bacterial adhesion of common pathogens and now they have studies done in various labs showing it blocks and destroys the sars-cov-2 virus. Also human clinical trials that are being done and showing amazing results.

Replied by Art
2089 posts


I wrote about Xlear Nasal Spray here on EC in early December of last year. That and melatonin are two major components of my anti-Covid-19 protocol. Here is a link to that post:

It is one of the 106 Covid-19 remedies listed on EC.


Xlear Nasal Spray
Posted by Art (Ca) on 12/03/2020 2089 posts

Previously on EC, I have mentioned the use of a nasal spray called "XLEAR" to help treat sinus infections and nasal issues. Studies now suggest it may be helpful in preventing COVID. See the top of this page for more information.

Replied by Art
2089 posts

So I have stocked up on Xlear nasal spray for family and friends to help fight Covid-19 as outlined in the new study I posted about. I even sent some to out of state friends who are infected with Covid-19 and have other preexisting health conditions to try and quicken their recoveries and to try and lessen any impact on their preexisting health conditions. I think the combination of high dose melatonin, Xlear nasal spray which contains both grapefruit seed extract and xylitol may be great for possibly controlling the virus quickly, lessening the effects and helping to speed the recovery process!


Replied by Lexie

Hi Art:

Your article about Xclear and Grapefruit Seed Extract is very interesting. Your "link" to the extract on Amazon seems to be just for the Xclear - and doesn't contain Grapefruit Seed Extract. So, do you recommend purchasing the spray and adding the extract to it? If so, How much do you add?

Thanks. Lexie

Replied by Art
2089 posts

Hi Lexie,

You will find that there is no need to add "anything" to the Xlear Nasal Spray as the Grapefruit Seed Extract (GSE) is already in it! Just go back to the Amazon link in the original post. Once at the link connection to the Amazon page, on the left side of the page you will see little boxes with images in them. Click on the fifth box from the top and it will show you the ingredients. Drag your cursor over the enlarged image and you can read that the ingredients are : Purified Water, Xylitol, Saline and Grapefruit Seed Extract with the GSE also doubling as the preservative!

So this product is ready for use just as it was used in the study! One bottle should be sufficient for one person for one course of the treatment outlined in the study for Covid-19.


Replied by Teri

I also learned about boosting the immune system with Zinc, D3 and C and if you are not feeling well Quercetin plus the Xlear nasal spray. Daily to this date I still have not been sick.


Just a word of caution for those with MTHFR, I've heard that some may be sensitive to Quercetin.

Xlear Nasal Spray
Posted by ShashiNYC (NYC) on 12/03/2020

It's simple enough -- and cheaper -- to create a DIY version of Xlear, which contain four easily accessible ingredients.

Replied by Art
2089 posts

Hi ShashiNYC, thank you!

That is very useful information on making a xylitol mix for nasal issues. I agree that a home brew can be less expensive if you are planning to use Xlear for many people, but if you are only using it for yourself and a smaller family, it will be cheaper and easier to just buy Xlear. One bottle should be all that is needed per person for the full treatment schedule outlined in the study. The lowest price I paid was less than $9 a bottle and the highest I paid was $15.

GSE is reported to to be a potent microbicide that is effective against over 800 bacterial and viral strains, 100 strains of fungus and a large number of single and multicelled parasites. Having to add GSE to the xylitol mix you linked to would also increase the price of the xylitol home brew, making it more in line price wise, with the ready to go Xlear Nasal Spray that contains both active components already. I paid $15 at CVS Pharmacy for one bottle of Xlear and less than $9 dollars a bottle for a 3-pack on Amazon which included free shipping. To me that is reasonably priced for a very good quality product that is ready to use against Covid-19. If you have to buy the nasal spray bottles, GSE, DS and Xylitol that would cost more for just a few users, but would be less costly if you are also going to be giving it to family and friends or if you plan on using it for a long time for sinus issues also.

In the case of Covid-19, as the Xlear Nasal Spray was used in the study, GSE may actually be more active than the xylitol against Covid-19, so inclusion of GSE is a must in order to achieve maximal effectiveness against Covid-19.

Thank you for the link/directions and feedback!