Article from: http://www.physorg.com/news163253821.html
Hydrogen peroxide marshals immune system (w/Video)
June 3rd, 2009
When you were a kid your mom poured it on your scraped finger to stave off infection. When you got older you might have even used it to bleach your hair. Now there's another possible function for this over-the-counter colorless liquid: your body might be using hydrogen peroxide as an envoy that marshals troops of healing cells to wounded tissue.
In the zebrafish tail fin imaged here, a small wound is inflicted at the tip of the fin. Red represents high concentrations of hydrogen peroxide, and blue represents low concentrations. The chemical burst far exceeds the single cell diameter and reaches well into the surrounding tissue. Credit: Philipp Niethammer
Using the zebrafish as an animal model, researchers in the lab of Harvard Medical School professor of systems biology Timothy Mitchison and Dana Farber Cancer Institute professor Thomas Look (http://www.dana-farber.org/) have discovered that when the tail fins of these creatures are injured, a burst of hydrogen peroxide is released from the wound and into the surrounding tissue. Teams of rescue-working white blood cells respond to this chemical herald, crawl to the site of damage, and get to work.
"We've known for quite some time that when the body is wounded, white blood cells show up, and it's really a spectacular piece of biology because these cells detect the wound at some distance," says Mitchison. "But we haven't known what they're responding to. We do know something about what summons white blood cells to areas that are chronically inflamed, but in the case of an isolated physical wound, we haven't really known what the signal is."
These findings are reported in the June 4 issue of the journal Nature.
Philipp Niethammer, a postdoc in Mitchison's lab, and Clemmens Grabber, a postdoc in Look's lab, initiated this research project with no interest in wound healing. Rather, they were studying a groups of molecules called reactive oxygen species, or ROS. These small oxygen-derived molecules, of which hydrogen peroxide is one, have the potential to be both helpful and hurtful. Niethammer and Grabber were simply curious to find ways to detect ROS molecules in an organism.
To do this, they took a gene engineered to change color in the presence of hydrogen peroxide and inserted it into zebrafish embryos. Once the embryos entered the larvae stage after a few days, this synthetic gene spread throughout the entire body, essentially "wiring" the fish so that any discreet location in which hydrogen peroxide appears would glow.
But how do you coax the fish to produce a reactive chemical like hydrogen peroxide in the first place?
Since white blood cells have long been known to produce hydrogen peroxide, one obvious way to initiate chemical production would be to inflict a small wound onto the fish, and then, using microscopy, observe patterns of this chemical as white blood cells gathered around the wound. But much to the researchers surprise, they found that hydrogen peroxide immediately appeared at the wound site, prior to the arrival of any white blood cell, and quickly disseminated into neighboring tissue.
They repeated the experiment, this time in zebrafish where they'd disabled a protein that was previously discovered to produce hydrogen peroxide in the human thyroid gland. Not only did hydrogen peroxide not appear at the wound site, but white blood cells failed to respond to the injury.
"This was our real eureka! moment," says Niethammer. "We weren't too surprised that we could block hydrogen peroxide production through this technique, but what we didn't expect at all was that white blood cells wouldn't respond. This proved that the white blood cells needed hydrogen peroxide to sense the wound, and move towards it."
Of course, zebrafish are not people, and while our genomes share many similarities with these tiny fish, it isn't yet clear that natural selection has conserved this process throughout the evolutionary family tree. Still, these findings offer something of a conceptual shift in how to view human conditions where hydrogen peroxide plays a role.
"When we look at how hydrogen peroxide works in people, this really starts getting intriguing," says Mitchison.
In the human body, hydrogen peroxide is produced primarily in three places: lung, gut, and thyroid gland. Because hydrogen peroxide, and the proteins responsible for producing other ROS molecules, are especially present in lung and gut, the researchers hypothesize that human diseases relevant to these findings would include any in the lung and gut that involve disproportionate levels of white blood cells, like asthma, chronic pulmonary obstruction, and some inflammatory gut diseases.
"Our lungs are supposed to be sterile; our guts are anything but," says Mitchison. "It's very logical that both those tissues produce hydrogen peroxide all the time. Perhaps in conditions like asthma, the lung epithelia is producing too much hydrogen peroxide because it's chronically irritated, which, if our findings translate to humans, would explain inappropriate levels of white blood cells. This is certainly a question worth pursuing."
Mitchison is currently laying the groundwork for investigating this hypothesis.
More information: Nature, June 3, 2009; 459 (7247) "A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish"; Philipp Niethammer, Clemens Grabher, A. Thomas Look, Timothy J. Mitchison
Source: Harvard Medical School (news : web)
I think I might have candida.I was considering just using the 3% hydrogen peroxide from my medicine cabinet until I did a little research.I have smoked for years so I know my body could use some extra oxygen.I wanted to know is their any foods, supplements, techniques or anything else I can do to produce hydrogen peroxide NATURALLY in my body? I read that it is in rain water and breast milk. I just dont want to dilute the 35% GRADE SO i WAS WONDERING CAN i GET IT ELSE WHERE?
(Seaside Town, MA)
(San Antonio, Texas)
We received an email this morning and apparently this website was mentioned on the radio show "Coast to Coast" last night about a hydrogen peroxide treatment. Did anyone hear it? If so, can you tell us what it was about? Thanks!
H202 and travel
Hi, I have just started on the H202 drops in distilled water. It's been one week and I am flying within Canada this weekend and wondering if anybody can tell me if I should take it with me or just stop for the weekend. I have lowered my dose in case I have to stop for the weekend but I really don't want to. Any help would be appreciated!
(Mineral Bluff, Georgia)
(San Francisco, VA)
I have a question. I have read alot about H202 therapy and I understand dilution ratio's, but I just read in one of the articles that store bought distilled water isn't pure enough it has to be double distilled? Can boiling tap water for X amount of time make it pure enough? the article wasn't clear on this. I just bought 12% food grade H202 from a local health food store and want to get started asap. Someone please shed some light on the water quality to be used and if boiling water is safe. Many Thanks.
(Perth, Western Australia)
(New Haven, CT)
This might be a rethorical question- tell me does taking antioxidants makes the consumption of H2O2 USELESS? and does a high level of oxygen in your blood (a result of H2O2 consumption) negatively affects the T Cells as was indicated by one of the EC readers?
(Panama City, Florida)
(Panama City, Florida)
Hydrogen Peroxide and DMSO
In the book "DMSO: Nature's Healer by Dr. Morton Walker (who acknowledges Dr.William C.Douglass, H202 advocator, in page vii), I read the following:
"If superoxide anions are present in quantity as a result of ecological alteration such as radiation toxicity, water pollution, chemotherapy, or other stressors, the body's ability to detoxify is affected. Instead, superoxide, and superoxide dismutase form hydrogen peroxide. Lipid peroxidation takes place. More hydroxyl radicals develop and bring on cellular damage with degenerative disease. DMSO offsets these effects and brings the body back to a more normal state."
"Free radical pathology is an intrincate part of virtually every metabolic dysfuction you can think of. To illustrate, cancer manufactures prodigious quantities of hydrogen peroxide, which then generate the hydroxyl radical. This is probably part of the reason why DMSO has proved to be valuable in the treatment of cancer."
*Bolds are mine.
I am very concerned because H202 is supposed to cure cancer. I don't understand. Does cancer manufactures its own hydrogen peroxide? Is hydrogen peroxide a danger in our blood and cells? It is nonsense.
I am taking hydrogen peroxide by inhalation right now. I have been following the advices of many physicians who advocate this molecule, including Dr.Williams.
Could you please give me an explanation? Am I misunderstanding something?
Thank you so much in advance for your help.
ACV and 35% H2O2: Can you take them both during the same time period?
Some people are referring to H2O2 simply as water. This is wrong!! H2O is water(2 molecules of Hydrogen and 1 molecule of Oxygen). H2O2 is Hydrogen Peroxide (2 molecules of each).
I am intrested in inhaling H202 and have question for experts out there. The part of the world where I live I could only find 6% H2O2 and now wondering how can I dilute the same to 3% H2O2.
I HAVE BEEN RESEARCHING THE H.P METHOD SOME TIME BUT I DONT UNDERSTAND THE STABILIZER ISSUE MY 3% SAYS (STABILIZERS) RIGHT ON THE LABEL, DO I WANT THIS OR NOT? AND WHY OR WHY NOT?
I am having trouble understanding the H2O2 Therapy-some say 3% in bath, some say 6%-7% Food Grade, some say 35% but indicate danger. I have been into "Orthomolecular Medicine" for 30 years.
I am taking all the major vitamins and minerals including-ginseng, aloe vera, ginger, hawthorne, turmeric curcumin, ginseng, bilberry, butchers broom, fengreek, 2ala's, chromium, garlic, bromlein, l-carnosine, coq10, bee pollen, calcium magnesium, potasium, flax seed, acidophilus, l-glutamine, worm wood, lecithin, grapeseed extract, selenium, zinc, glucosamine chondroitin, pancreatin, pau d' arco, l-argine, l-ornithine, l-lysine (I vary what I take).
I have had Candida for 20 years, now diabeties, angina, hardening of the arteries. Bluntly - H2O2 Seems the safest however there is much confusion about the correct dosage to take and the percentage of peroxide. Appreciate your prompt assistance in advance.
I take 2 teaspoons of 3% hydrogen peroxide in a half glass of cranberry/raspberry juice per day. This is equivalent to 16 drops of 35% h202. Goes down real well, no side effects, no stomach problems.
My question is, am I reducing the effects of h202, releasing 02 by mixing the h202 in juice instead of water? btw, sometimes i have taken 3 teaspoons of 3% h202 in a glass of cran/rasp juice, with no ill effects. (equivalent to 24 drops of 35% h202)! Need your inputs.
How do I use h202 in a steam inhaler? I have an asthma and I want to be helped.
If the goal of peroxide therapy is to flood the body with oxygen, would an oxygen machine given for bronchitis work just as well? Thank you!