DMSO Health Benefits, Dosage and Application Tips

| Modified: Apr 09, 2021
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DMSO for Pain, Wounds, Arthritis

DMSO, or dimethyl sulfoxide, has been used for many years by athletes to treat painful muscles and joints. DMSO builds up the white blood cells and increases immune production of migration inhibitory factors (MIF) by macrophages.

DMSO has been associated with a number of therapeutic benefits, such as for the healing of wounds; its use as an anti-inflammatory, anti-bacterial, anti-viral, and anti-fungal; softens collagen, helps eliminate hydroxyl free radicals in the body, stimulates the immune system, increases interferon formation, reduces the number of platelet thrombi, and is a potent diuretic. DMSO skin remedies are useful in treating topical fungal infections.

DMSO Health Benefits

On this page, you will find hundreds of DMSO reviews from Earth Clinic readers dating back over the past 20 years!

Everything from how DMSO alleviated pain to DMSO for herpes.

Our readers have created a number of discussions over the use of DMSO for migraines, burns, hair loss, scars, wound treatment, muscle strain, and even for ticks. Check this page for a list of ailments treated with DMSO. Also do a sitewide search to discover many more ways DMSO has been used!

Where to Buy DMSO

Amazon sells a number of reputable DMSO products.

NO ODOR DMSO - Dimethyl sulfoxide liquid (3.4 Oz - 100ml), Pharmaceutical grade, High purity, Heiltropfen


DMSO Liquid Concentrate 99% Pure 16 fl. oz.


DMSO Dimethyl Sulfoxide Low Odor in Glass 8 oz Bottle 99.995% Pharma Grade


Let us know if you try DMSO for any of the ailments listed here, and especially if you know of a treatment that we do not yet have listed!


Acne

1 User Review
5 star (1) 
  100%


Posted by Jessi (Murrieta, Ca) on 12/06/2011
5 out of 5 stars

I have been using DMSO for acne and it's the only thing that has seemed to help reduce the inflammation and really help with my severe acne. It does make my skin very dry and flaky, but if I use an oil free moisturizer it seems ok.

I have been using the DMSO morning and night and I just roll it over my face before my other skin care products. There is a slight/mild tingle and stinging for about 5 mins. I am also using on top of the DMSO the Jan Marnin Bioglycolic Bioclear Lotion which I think is working well together with the DMSO. I'm not able to use Benzyol Peroxide because I am allergic to it, so the DMSO has been an amazing cure for my acne. I truly can't live with out it. If you are suffering from acne I would definitely recommend trying the DMSO. I use the roll on 70% DMSO 30% aloe or the 70% DMSO 30% distilled water. It's $10.00 on Amazon .:)

Replied by Gri Court
(Spain)
11/01/2017

hi,

I 'd be careful with DMSO when using typical skin care products which most of the time have ingredients one doesn't want in its system.

Replied by Riles
(Australia)
01/19/2018

DMSO is a good carrier Gri Court, that is why you should be careful.


Arthritis, Cancer

1 User Review
5 star (1) 
  100%


Posted by Kenny (Minor Hill, TN) on 04/06/2021
5 out of 5 stars

I have been using and recommending DMSO for many years! It cured my arthritis, and has cured three people I know of cancer! Yes, even stage four cancer! DMSO is a miracle drug! I do not recommend drug to be taken for preventative reasons, but I think DMSO can even help to clean the arteries and heal the heart, as I have also lived with an irregular heartbeat all my life but I've noticed that after taking the DMSO for my arthritis my constant irregular heartbeat has also vanished and now only once in a while feel my heart out of rhythm and even them not as pronounced as before!

I've been an herbalist most of my life and DMSO and wild lettuce have impressed me more than anything else!

Replied by Sanja
(Ontario)
04/09/2021
2 posts

How do you take DMSO please?

Replied by Rebecca
(Cedar Hills, Utah)
04/09/2021

Hi! I have RA and I was wondering what your protocol for Arthritis is. Thank you so much. Do you eat it or rub it on the skin??? How much, etc.

Replied by Lou
(San Francisco, CA)
04/09/2021

I have few questions for you -

1. where do you buy DMSO?

2. what purity DMSO and type?

3. how do you take it? and how many times?

thank you

Replied by Rae
(Texas)
04/09/2021

Is there a brand you can recommend? I just had 3 MRI's and apparently I have arthritis in my back. I deliver mail so I need something that really works and I truly believe this could help.


Bone Spur

2 User Reviews
5 star (1) 
  50%
1 star (1) 
  50%


Posted by Alicia (Abq., NM) on 09/22/2014
5 out of 5 stars

I've been suffering with a very large bone spur under my Achilles tendon on my heel. Every step feels like a knife stabbing me. I read about DMSO and bones spurs and decided to buy some. I got the gel 70% mixed with aloe vera. I've been putting it on for 2 days and I cannot believe the difference! I am thrilled! The only thing that bothers me is that when I put it on my heel, I have a tightness in my chest that I don't normally have. I take thyroid meds and am wondering if it is increasing the absorption. I also take several BP meds and I don't think it's bothered those. Has anyone else felt it has affected them in this way? And, should I dilute it with distilled water or what. I think this is really really effective and would like to continue using it but don't want to mess myself up.

Replied by Nick
(Muntinlupa, Philippines)
11/24/2014

DMSO is known to potentate other substances, such as drugs. The Blood pressure drugs will be much more effective in getting into the cells, and work better. I read a person could use up to 10 times less medication and get the same results. Make sure you don't take the BP meds at the same time you apply the DMSO. Make sure they are separated by 4 or more hours.

Blood Pressure drugs and DMSO should never be mixed together or taken with each other. The pressure will fall too low.

If you are brave enough, you could take 1/10th BP drug and DMSO and monitor BP to see what the effects are. You might even be able to stop taking the BP drugs all together with time and experience. Just be careful.

Replied by Jorge
(Redmond, Wa)
02/01/2015
1 out of 5 stars

Warning

DO NOT DO WHAT NICK SUGGESTED. First of all, taking your blood pressure medication with DMSO will cause the amount consumed to rapidly filter into your bloodstream, which may cause a precipitous drop in your blood pressure. Second of all, blood pressure medications are designed to reach a certain concentration in your blood for a given amount of time; even though it will be more rapidly absorbed, the final concentration, if you use 1/10th of a pill, will be 1/10th of normal. This is a bad idea all around.

Replied by Anthony
(Oxnard, Ca)
12/03/2016

Yes, that's seems like the case because DMSO is a very effective solvent and transporter, absorber etc. so you would need to use it more intelligently, especially if your taking medications because those would become more concentrated and more effective.

Replied by Patty
(Pennsylvania)
10/24/2017

Alicia, I am on thryoid scripts also.I felt anxious first taking the DMSo but at the tine I had a dose of CBD oil in my system also. DMSO of what I have read states that you must be careful because the DMSO will increase the efficacy of the other meds that you are on. I cut my thryoid meds down to half the dose and so far everything is fin, in that respect. Think about that with your BP meds, if that may be better for you while on DMSO. Otherwise it is like you are increasing your BP meds which may be harmful. Chest tightening is a concern that should not be taken lightly. I had that happen once when taking Imitrex a few years back and the dr took me off that med. I was not on DMSO back then so it had nothing to do with that. Good health to you!


Burns

4 User Reviews
5 star (4) 
  100%


Posted by Crystal (Abuja, Nigeria) on 07/26/2017
5 out of 5 stars

I used DMSO for third degree burns and it healed after one week without scars, Even hairs were preserved without keloids.

Replied by Robert Henry
(Ten Mile, Tn.)
07/27/2017
5 out of 5 stars

CRYSTAL,,,,,,,,, yep, DMSO is a miracle compound that I learned of first hand when I worked for CZ back in the 60's. At that time it was made in the CZ Bogalusa, La. paper mill. The Super was a friend of mine and related lots of stories about the employees that worked in that area. None ever had a cold or flu. Also, he related how DMSO cured steam burns to his wrists as you say in your post. Like the Good Book says, He has provided all you need.

======ORH=====


Burns
Posted by Pammy (Malibu, California, United States) on 07/03/2010
5 out of 5 stars

One of the most amazing treatments I have ever used is DMSO for burns. I have had serious burns and minor burns.

Usually I just open the container and slap a big tablespoon of DMSO on the burn. It is best to do it right away. I keep it on for about 1/2 hr. I keep a jar in my kitchen for the possibilities of getting burned at the stove. It takes the pain away immediately and the pain never comes back. You can apply a little each day for awhile, but I have not found that necessary. I wish every one knew about this as burns can be so painful. And the burns heal up nicely.

It is either Canada or Alaska that they use DMSO in ER for burns. Blessings to all. Pammy

Replied by Lolo
(Canada)
03/28/2018

Nope, not Canada. I was burned second degree on most of my right thigh. ER did not use DMSO.


Burns
Posted by Bill (Santa Ana, ca) on 09/03/2007
5 out of 5 stars

I burned my finger one day at home. I quickly grabbed the DMSO washed my finger, poured it over the finger. The pain and swelling stopped immediately. No subsequent problems. While winter hiking in the Sierras a girl in our group burned her hand on a hoy stove. I applied the DMSO from my back pack. She came to me the next morning to say she had no distress at all from the burn. I also used it on my mother's face when she fell on the cement smashing her glasses and nose. It moved the blood right out. The next day she had on a yellowing of the skin. Great stuff. I carry it everywhere.


Calcium Deposits

1 User Review
(1) 
  100%


Posted by Leo (Camrose, Alberta Canada) on 05/23/2009

Does anyone have experience or information about massaging DMSO with enzymes to dissolve calcium deposits? There is a patent application on the web about that, at http://www.freepatentsonline.com/4250167.html?query=4250167&stemming=on, referencing DMSO and Papain, but has anyone experience with this? Thanks. Leo

Replied by Stuart
(Oklahoma)
12/07/2014
0 out of 5 stars

Leo,

Tested 1.0 ounce Papain dissolved into 4 ounce of DMSO gel (90%) applied topically over the spine.

Papain mix applies very sticky; must let it dry before you put on shirt, or it will glue together.

More over, the mix liquifies to a amber goo after two days. I will dispose the prepared mix, and just make 'just enough' mix for daily use. It smells bad when the mix ages.

I may recommend using a salt shaker and apply papain powder directly to DMSO applied to spinal axis.

Results after three days is still unknown. No issues, positive or negative; none is expected until about two weeks daily application.


Chronic Allergies

1 User Review
5 star (1) 
  100%


Posted by Deborah (La Honda, Ca) on 01/07/2012
5 out of 5 stars

I just wanted to state that I read a thread about some people in Australia taking a few drops of pure DMSO in a glass of purified water daily and decided to try it. I have pain from soft tissue damage from a few injuries and thought it might help. What I did not expect was that my cronic stuffy nasal passages from allergies would almost instantly clear! The first day it happened I did not attribute it to the DMSO but now after four straight days of being able to breathe fully within minutes of taking it; it is now clear there is no doubt. I have ordered the book recommended here and will see what else I can expect.


DMSO + Lugol's Iodine

3 User Reviews
5 star (2) 
  67%
(1) 
  33%


Posted by Cl503 (Oregon, United States) on 09/23/2014
5 out of 5 stars

DMSO and Lugol's Iodine: yea- I think.

After a detoxing bath filled with epsom salts and borax, I mixed some DSMO cream I had with iodine and applied it to my lower back, and then kind of smeared more iodine on my chest. It couldn't had been more than 3 droppers full of 2% lugols and within about 5 minutes I became aware of a slight pain which I realized was my thyroid. It kind of scared me, it didnt really hurt, it was just that I was very aware of it, and had never felt it before. Anyone else experience something like this? I know DSMO acts as a carrier and allows things to be absorbed, the whole blood brain barrier thing..?

Replied by B
(Nevada, US)
01/22/2015

You used a couple dropper fulls of 2%, that is a lot! Even after the chernoybl nuclear fallout in europe people close were told to take no more than 1-5 drops a day to protect their thyroids of lugols 2% by medical doctors.


DMSO + Lugol's Iodine
Posted by .A (Wind, Ont) on 09/22/2010
5 out of 5 stars

In reply to:

Posted by Jane (Hoddles Creek, Vic Australia) on 01/20/2010: Lugol's Iodine and DMSO - a couple of sprays on the skin once only I almost fainted 3 times that day at work and did not repeat the trial, as a nurse in home visits I didn't feel it was appropriate to faint on the job!

Yes, DMSO and Lugol's will do this but when applying this add sea salt internally and selenium and this will offset this.

Remember, the Dmso is carrying the Potassium in the system so it will lower blood pressure so you will need salt to balance it out and the selenium to regulate the iodine--I use this with an SKI/lugols I make with a 5% DMSO solution and noticed the same thing. You sleep deeply and rest like a baby but it can have a drowsy effect when not having salt.


DMSO + Lugol's Iodine
Posted by Jane (Hoddles Creek, Vic Australia) on 01/20/2010
0 out of 5 stars

Lugol's Iodine and DMSO - a couple of sprays on the skin once only I almost fainted 3 times that day at work and did not repeat the trial, as a nurse in home visits I didn't feel it was appropriate to faint on the job!


DMSO Activates Old Antibiotics

Posted by Robert Henry (St George Island, Fla.) on 09/13/2015

HI U OLE PATOOTS DOIN, , , , , , yep , I'm back on the beach getting my dose of Vitamin D from the sun , Magnesium from the gulf , negative ions from the waves to neutralize my free radicals. All compliments of our Lord.

I am also rereading my book on DMSO and retention is only about 20% when you read. Well, I missed this point on the first go round, but it really hit home on my second reading.

All know that bacteria and virus, etc. mutate and become immune to antibiotics. Ain't that right? Listen up, because this is the good news. Studies show that when you use DMSO with old antibiotics they become effective again. Is that great or what? The problem is that the patents have also run out and the old antibiotics are now dirt cheap..... so there is no incentive to re-engerize them. We must have new suff that is patentable so we can all go to the pore house.

All is not lost because what I am 'ciphering from this is that anything you use to address an infection or such will be enhanced by toping it off with DMSO. I don't think that statement is a stretch, but you the doctor and you make the call.

Me, I do DMSO to take things into my body and fixing to use it with my nebulizer for things that I do through my lungs. Maybe I'll become as famous as our idol, Bill Munro. If I keep posting then it worked. If not, then it did not work.

Tired of fresh shrimp and seafood gumbo so I'm grilling steaks tonight. Eat your heart out.

========ORH========


DMSO and Aloe Vera

3 User Reviews
5 star (3) 
  100%


Posted by Man (America) on 12/30/2013
5 out of 5 stars

I have recently bought Aloe Vera juice and put it with DMSO.

I really haven't noticed that it helps do much of anything but it hasn't hurt anything either. Even if it is just an inert substance, it still can play a role in my tinctures.

Aloe vera juice is a way to cut the DMSO to a lesser strength and for all I know, it may help something. So I am using Aloe Vera Juice in my blends now for topical application.

It may help soothe the skin but I don't see that it stops the irritation when used with DMSO cut with it.

My experiments with DMSO and Aloe Vera juice have been Straight DMSO with 30% Aloe; 40% and 50 % blends and I don't find any reduction in irritation.

When I add this to the Cayenne extract and make a blend of that. I find no irritation at all but I get the side effect of warmth where the blend is applied and it feels quite good. So a bottle filled with 50% Cayenne extract and 25 % DMSO and 25% Aloe Vera juice and a tiny spot of glycerin has a really good effect, mild.

I heated it up today by applying straight cayenne extract on top of the blend and it draws moisture and really heats up nicely on the skin. In summary, I can't tell what Aloe Vera does but I like what I read about it and it is a God-made plant it is a leaf. The leaves of the tree are for the healing of the nations from Revelation chapter twenty two.

Replied by Mike 62
(Denver, Colorado)
12/30/2013
5 out of 5 stars

Right on Man from America: The joint formula I use says right on the tube that the aloe vera base carries the herbal extracts into the joint. Like you, I add cayenne for heat. Works great all the time.

Replied by Man
(America)
12/31/2013

Thanks Mike, I don't know if there is a better "heat pad" than cayenne extract. I love the stuff.

Replied by Riversidian
(R.I., US)
06/25/2014

aloe is dead in any form but from a live leaf

Replied by Melanie
(Mansfield, Pa)
11/05/2018

Is this true, that aloe Vera gel is dead unless you take it from the plant right then and use it?


DMSO and Aloe Vera
Posted by Susan (New York) on 02/08/2013

Bill from San Fernando, can you explain how to do this (from Ted's posting)?

DMSO must be used together with aloe vera oil to prevent inflammation however.

Thanks.

Replied by Bill
(San Fernando, Philippines)
02/08/2013
5 out of 5 stars

Hi Susan... The preferred method of using aloe vera with any DMSO topical protocol is to apply the DMSO protocol first, let it be absorbed into the skin and the skin is dry, then apply the aloe oil on the skin afterwards. The aloe vera helps to rehydrate the skin and prevents skin irritation which can sometimes arise with DMSO use. I have bought a DMSO solution that also contains aloe vera - it's all I can get in the Philippines -- this is the other way of doing it. But I still think that the first method I described is better.

If you're using DMSO on its own, say, to help against an injury or arthritis then you will be using it on the same spot over and over again -- snd this is where sloe vera is quite useful -- it will help to prevent skin irritation. But if you are just using DMSO as an internal delivery mechanism for a nutrient like lugols iodine, then you should try and use the protocol in different areas of the body -- thus also reducing the possibility of skin irritations.


DMSO and B12

1 User Review
5 star (1) 
  100%


Posted by Vicky (Bangkok, Thailand) on 04/29/2010
5 out of 5 stars

I plan to do the recommendations of Dr. David Gregg dissolving Vitamin B12 in DMSO:

"The absorption of vitamin B12 requires a highly specialized process which tends to become less effective with age...I realized that if I dissolved vitamin B12 in DMSO, it might carry it directly to my blood stream through my skin. I tried it and the results were dramatic for me, far greater than any impact I had ever felt from oral or sublingual tablets. I put some of my vitamin B12 tablets obtained at a health food store into a two liquid ounce bottle with an eyedropper and filled it with DMSO. It took a couple of days for the tablets to fall apart. Once they did, I put an eyedropper load on one arm and rubbed it in. In approximately one hour I started to feel very good, which was a sense of general strength and well-being."



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