I've been suffering with a very large bone spur under my Achilles tendon on my heel. Every step feels like a knife stabbing me. I read about DMSO and bones spurs and decided to buy some. I got the gel 70% mixed with aloe vera. I've been putting it on for 2 days and I cannot believe the difference! I am thrilled! The only thing that bothers me is that when I put it on my heel, I have a tightness in my chest that I don't normally have. I take thyroid meds and am wondering if it is increasing the absorption. I also take several BP meds and I don't think it's bothered those. Has anyone else felt it has affected them in this way? And, should I dilute it with distilled water or what. I think this is really really effective and would like to continue using it but don't want to mess myself up.