I have been using the Bach Flower Remedies (BFR) to help me with a bad, bad bout of depression and it didn't seem to be working for me. In desperation I read about Acetyl-L-carnitine (ACL) and it being an amino acid (a building block for proteins) that is naturally produced in the body. It helps the body produce "energy. " BFR works on energy so, I started taking the ACL and later that 1st night when I took the BFR it started to work almost immediately. That horrible knot in my stomach started to come on done. This morning when I awoke the knot was back and felt like I was at the end of the world again. I put the BFR drops in my coffee and sipping my coffee I could feel the knot being undone again. You just have to get past getting out of bed and I know how hard that can be.