taken from internet...thoughts?))
Study highlights role of glutamine in absence of glucose in growth of B cell tumor.
Cancer cells have been long known to have a "sweet tooth, " using vast amounts of glucose for energy and for building blocks for cell replication.
Now, a study by a team of researchers at Johns Hopkins and elsewhere shows that lymph gland cancer cells called B cells can use glutamine in the absence of glucose for cell replication and survival, particularly under low-oxygen conditions, which are common in tumors.
Writing in the Jan. 4, 2012, edition of Cell Metabolism, Anne Le, M. D. , and a team of investigators collaborating with the Johns Hopkins Brain Science Institute, say the finding is critical for developing innovative cancer therapies because it offers "proof of concept" evidence that curbing the growth of B cell cancers can be accomplished by inhibiting a glutamine enzyme called glutaminase.
Le notes that although little is known about glutamine's role in the growth of B cell cancer, the amino acid circulates in the blood at the highest level among the 20 amino acids that do so.
The tricarboxylic acid cycle (TCA or Krebs cycle) is classically regarded as a pathway for glucose oxidation. However, the experiments by Le and the team show that B cells oxidize glutamine when glucose is absent.
The study also found that when oxygen is scarce, there is enhanced conversion of glutamine to glutathione, an important agent for controlling the accumulation of oxygen-containing chemically reactive molecules that cause damage to normal cells.
When the investigators used a glutaminase inhibitor, cancerous growth of B cells was stopped in petri dishes.
"The flexibility of the TCA cycle in using both glutamine and glucose pathways may be important for cancer cells to proliferate and survive, especially under the low-oxygen and nutrient-deprived conditions often encountered in the tumor microenvironment, " says Le.
Now, perhaps, scientists can exploit that survival strategy to stop cancer, according to former Johns Hopkins scientist Chi Dang, M. D. , now at the Abramson Cancer Center at the University of Pennsylvania. "A broader and deeper understanding of cancer cell metabolism and cancer cells'ability to reprogram biochemical pathways under metabolic stress can be a rich ground for therapeutic approaches targeting tumor metabolism, " he says.
In addition to Le, an assistant professor in the Department of Pathology at the Johns Hopkins University School of Medicine, other researchers from Johns Hopkins who participated in this study include Sminu Bose, Arvin Gouw, Joseph Barbi, Takashi Tsukamoto, Camilo J. Rojas and Barbara Slusher. The Johns Hopkins Brain Science Institute, where Tsukamoto, Rojas and Slusher are faculty, is pursuing the development of new glutaminase inhibitor drugs.
(Ten Mile, Tn)
HI U GOOD FOLKS DOIN, , , , , , , Thought I'd bring you up to date on the carcinoma that I had on my hand. First, I tried to handle it by treating it with iodine. That was affecting it but too slow so I got my doctor to cut it out. It healed very well, except there was a tiny black spot still there. Even though the pathologists reported to the sergeon that he got the entire cancer, I knew he had not. I then ordered Bloodroot Black Salve from Uragury from the American the FDA sent to prison for selling the stuff here several years ago. Anyway , the salve caused the cancer to harden and start to rise just like it did with the iodine. Only this time it also ate deep into my hand. Dear hearts, there is much pain to this procedure. Soon the entire thing came off and left a pretty deep hole in my hand. That is what it is supposed to do. Now the hole has filled in and only a small scab remains. I am satisfided that the cancer is gone. On future skin cancers, I will use the solution made from the Egg Plant. It is slower but is not as agressive as Bloodroot Black Salve. You got to get the Egg Plant solution from Australia.
Got ATS to tell you, but you will have to wait 6 months on this one. I got another serious health problem and have elected to go the natural way. It's a goodie and I kinda scared, but I got a program and it will be thumbs up or thumbs down. At 76, I have lived a full life and am going out with dignity one way or the other.
Ya'll behave for a change. ==ROBERT HENRY====
My son is fighting 4th stage cancer and I was told cayenne pepper was good for this. Have u ever heard of this?
(Calgary, Alberta, Canada)
(Nagpur, Maharashtra, India)
HI U GOOD PEOPLE DOIN. Just became aware that there is a test developed by Purdue U that can tell by a particular protein in your cells if you have cancer or not. It is 5 to 6 years ahead of our current accepted technology. We just took the test and will know in a few weeks if we have a problem or not. Also, they have a protocol that can eliminate these cancer cells in this early stage. Imagine that. Naturally this is all early science stuff. We will keep you posted on the results.
Yo Redneck Buddy == ROBERT HENRY=====
(Elk Grove, Ca, Usa)
Cancer is not viral. It is a fungus. All sickness was fungal back in the day until antibiotics came into play. That is when bacterial started & viral is used alot when the allopathic medical field is not knowledged or is guessing which they are any way. They are practicing medicine. They are taught & allowed to only treat the symptoms because of the FDA, Big Pharma, ect. It is all about GREED (money) not what is best for us or to heal but usually treat us with things that cause bad side effects or death. Get knowledged by going to these websites. NATURAL NEWS. COM & NATURALNEWSRADIO. COM. LISTEN TO ROBERT SCOTT BELL & MIKE THE HEALTH RANGERS SHOWS & CHECK THE LINKS OUT & DO YOUR HOMEWORK (RESEARCH) ALSO MERCOLA. COM GET BLESSED WITH THE KNOWLEDGE & THEN SHARE IT
My Wife has colon cancer, and is now suffering with extreme cachexia, I have recently started her on hydrazine sulphate to reverse it.
But I have also read about chloroquine (anti malarial drug) which is now under clinical trials, as it inhibits autophagy.
My question do you think it is possible to combine both treatments in an attempt to starve the cancer?
Hi I need to know what is the difference betwwen a nottingham grade 2/3 cancer and a stage 1, 2, 3 cancer Confussed??? I have would also like to comunicate with someone who has breast cancer and what treatments are working well in shrinking a second tumor. Thanks- I have a few other posts and any inofrmation is so so appreciated. thanks, Kat
(Kansas City, Missouri, Usa)
I have a loved on with a cancer rare but their enzymes are very low.. My question to anyone that can answer how do you keep your enzymes to balance.
If you read internet blogs, you will find claims that everything under the sun treats cancer (and everything causes cancer).
Knowing many friends and relatives with different types of cancers, I want to be able to help with alternatives to chemo and radiation. Even if they choose to go with chemo and radiation, and you certainly can't blame them when they're fighting for their lives, perhaps there are some alternative therapies that help the process.
Of course, there are some legitimate alternative treatments out there. Please reply with the very best alternative treatments you know of, especially if you've witnessed the treatment's success for yourself.
There have to be some treatments that, when applied together, do much better than a singular treatment. There are also different cancers that may be better treated with one type of treatment versus another.
I've listed some treatments I've heard about:
Essiac tea, Budwig Protocol, Hydrogen Peroxide, Antioxidants, Mega doses of Vitamin C, detoxing, Omega 3 and other Omegas, Ozone therapy, group prayer, energy healing, Acupuncture, Tesla Coil, hot springs bathing, sulphur springs bathing, oil pulling, hyperbaric chamber, Coconut Oil, Coenzyme Q-10, Ubiquinone.
Please share your thoughts on promising individual treatments and combinations.
(Manhattan, New York)
I received this link from a relative. Some seems unclear to For example. Ted says no potassium gluconate, yet says it blocks cancer glycosis. I would like to have the protocol listed by supplement, amt to be taken and when including source and cost, as well as things to avoid. I was given 6 mo. - 1 year as of Jan 1 this year. Have not done chemo, radiation or surgery. What do you think of DIM? Thank you for your help.
The Great Cancer Hoax, Part II, the cure the FDA tried their best to shut down... From the Dr. Mercola website. A video, only available to watch until 24 September.
Excellent study on curing cancer... Endorsed by Dr. Mercola
I am looking for a clinic that uses dmso to treat my condition. please advise.
Can Ted tell me about ACV, B. Soda, & honey mixture and is this ok for cancer.. ?? I thought I read that the B. Soda gobbles up the cancer as the cancer Thank you go after the honey and a blast of B soda will kill the cancer cell...??
Just found this article and thought others concerned about cancer treatments might find it helpful: