I woke up with COLD SORES on a Tuesday morning, and I was going to fly across the country to visit my boyfriend that Friday! No way was I going to see my boyfriend for the first time in a month and NOT be able to kiss him! I used ice AND lysine AND acetone. Here's how:
LYSINE: Took 3000 mg as soon as I got up, 2000 mg at lunch, and 2000 mg at bedtime. The second and third days, I took 2000 mg at each of the same times.
ICE: Iced ASAP for about 20 minutes. This stopped the tingling and pain for about half an hour after I was done. Iced again a few hours later for another 20 minutes.
ACETONE: After icing, I used a Q-tip to CAREFULLY soak each cold sore with acetone for about a minute. As soon as the tingling or pain came back, I soaked the sores with the acetone again. I did this for about an hour and a half, then rinsed my lips with lots of cold water. I soaked the sores with acetone again one time right before going to bed. The second day, I used the acetone one time in the morning and one time at night.
The sores were GONE by the end of the second day. My lips WERE red and puffy for another day or so in the places where I'd used the acetone -- so be aware that you might be replacing your cold sore with a chemical burn.
I have not tried using these three things separately, so I can't tell you which one is the best. But using all of them together worked for me!