A friend of mine had peripheral neuropathy due to chemo treatment. I recommended B-vitamins, but knowing the seriousness of this, I was not willing to take chances. I advised her to buy a very good food-based B-Complex and an additional B-12. She had a very quick recovery (symptoms diminished in one day and resolved within a week or so, with no recurrence throughout chemo). Her neuropathies had just started a week or two before, so I'm sure that helped her heal quickly. The B-complex & B-12 supplements she took were Vitamin Code/Garden of Life. This is a raw, whole food formula with live probiotics and enzymes. Find it at any healthfood store in the US. She took it according to the package directions. The amounts are much less than typical supplements & it's a little pricey, but there is absolutely no doubt that this one was well-absorbed and effective for my friend. Her recovery was nothing short of amazing.
Having had plenty of back problems myself, I learned to be mindful of how mental stress causes me to tense up in my back and hips. Just being aware of this has helped me mentally combat the stress and relax my back. Easier said than done, I know, but I wish you all the best.
(West Plains, Missouri)
Vitamins b1 to b6 and b12, plus ala and butcher's broom, reduced my diabetes neuropathy by about 70% and another 10% by not using a recliner chair to watch tv. Maybe it presses on the nerves in the legs.
I've been using MSM for years to prevent gallstones and my neuropathy just continued on. My initial neuropathy was from B12 deficiency, which was from chronic diarrhea, which was from vaccine injury.
I tried B-12 patches for my terrible neuropathy and my cramping and shooting/stabbing pains got worse..I thought all B vitamins were water soluable so this wouldn't happen. Anybody have any suggestions as why this might happen? Thank you.
Hi Al; I found that the only substance that helps my neuropathy is B12... Alot of it, every day. ( I'm now taking 10 mgs. of sublingual methylcobalamin daily.)
Also, I'm very sensitive to acidic supplements, including ALA and ALCAR, Unfortunately.
When nerves are healing, there can be increased pain for a time, so it can be difficult to determine whether healing or regression is occurring.
Since tinnitus and pain/coldness is returning, my guess is that this is a regression.
I believe that my case could be caused by some genetic defect, some problem with B12 transport throughout my body. I'm having to rely on passive diffusion to distribute it. I've found this condtion to be rather common, not so rare.
Some months ago, I posted about zinc also being helpful for neuropathy. I have also found that when I've tried higher amounts of it, it actually can interfere with B12. ( zinc can displace cobalt, and vice versa). Too much zinc can displace copper and cause neuropathy, copper deficiency type.)
I understand how painful and frustrating this can be, I hope you can find what works best for you.
Looking for Connie from Utah...
You gave me a remedy for my Periphal Neuropathy... I am now up to 10,000 mcgs of B-12 and still have pins and needles and severe cramps in the middle of the night in my calves... My legs are cold from the knees down and we're in a heat wave in August.... It seemed to subside initially, but the full neuropathy is still there... I have been doing it for about 3 weeks.. Is this something that may take months to resolve? Any feedback will be greatly appreciated... If you recall I believe that hep-c has caused this neuropathy...
(Avon, Ct, Usa)
(Alvena, Sk., Canada)
I also took the same Bs as Shrikant (the fat soluble B 12 & Metacobalin) and my neuropathy in both feet that I had for a few years got better THE NEXT 24 hours I could tell - a difference for the better. I am now still on the fat soluble Bs and it has been 1 1/2 years now. The tingling, the extreme sensitivity, the sudden jerking jolts of what felt like electric shocks within my feet are all gone.
Only thing is lately, I have noticed a tightness appearing and I cannot bend back my toes towards me comfortably. Don't know why...
Hi Mark; This doesn't look easy, but I'll put forth some guesses. Zinc may be needed. It is often times low in people who have become ill with cancer and a large variety of infections. Zinc is active throughout the body, including the nerves. The symptoms of zinc deficiency usually include problems with taste and smell, gastrological disturbance, gonadal disturbance, and growth problems, but there can be many more symptoms. Some types that are easier to find are; zinc gluconate and opti-zinc; I have found these to be effective. Also, a food derived zinc may be gentler on the stomach if sub-divided. There's a zinc-l-carnosine type that may also be easier on the stomach. If taken for long term, a small amount of copper may be needed. ( There are cases of neuropathy that were caused by zinc toxicity that then caused a copper deficiency. These cases were the result of extreme amounts of zinc used, however... in the form of denture adhesives.)
Also, some supplements can worsen neuropathy if taken in too high doses for an individual. B1, B6, ALA, Acetyl-L-Carnitine, etc, may cause irritation.
I found B12 to be most effective for my neuropathy, but it took many months to heal... About a year. But I've also found Zinc to be enormously beneficial for nerve healing. It may take a month or so to see results.
My neurologist has recently informed me that supplemental B6 can build up in your system to toxic levels and cause nerve damage. I stopped all supplements immediately. I am now getting some relief from 1tbs unfiltered, unheated, organic ACV mixed with unfiltered, unheated, organic honey in a glass of hot water, 3x per day. Do your research before you make changes or try something new :)
Benfotiamine for Neuropathy
Hi my.bame is Jacqui. I am now 82 years of age.
I had the worst neuroo as thick pain around 3026. Every time I P Bank, burning like fire, crushing. Electric shocks, etc. Had ne constantly scream. Cause not known. I am not diabetic but I have chronic Lyme disease with multiple co infections including Bartonella. I was on Gabapentin that worked initially but when it stopped was switched to lyrica and then horizonta. Nothing worked.
At the time I tried Aloa Lipoic Acid but it had no effect on relieving the pain, but the dosages I took were co miserably lower than 600 mg that I notice is now recommended.
Out of desperation I started to experiment with high dosages of Benfotiamine. It is a synthetic form of vitamin B1 so that it iis made fat soluable and it can enter the cell wall ( and therefore nerve cells) making it highly more effective than ordinary B1 ( thiamine(. It is known to be effective & often used for diabetic neuropathy.
I learned about it in 2005 because I had used it successfully then when I had neurologic pain in my left small toe. The usual dosage is about 300-600 mg.
At tt time I took a little more & it was successful in stopping the sensitivity and pain ( even a sheet touching the toe area would caue pain(). Eventually I stopped using it. (At the time I was not aware that I had chronic Lyme disease. I believe that is the main cause of my beuropsthy(
So, 11 years later when I had severe neuropathic pain in my legs ( surprisingly not in my feet until later on) I experimented with Benfotiamine. I was desperate and decided to take increasing amounts until hopefully the pain diminished. I found the correct dosage. 1,200 mg ( 4 300 mg capsules) every 4 hrs. I put it on a timer and took it at the middle of night. I remained on that dosage for four years. Sometimes I could decrease it. When I had Covid the neuropathy got worse and going back to 7,200 mg a day was not enough. I doubled, possibly tripled that dosage and the pain went away. Eventually I was able to decrease the dosage dramatically..
I have also found that grape seed extract, high in resveratrol also have dramatic improvement and with very high dosage ( about 1 tsp of the piwder - in a drink & extremely bitter) I could reduce the Benfotiamine. ( BTW, for years I took high dosages of tumetic, by the tablespoon very effective for my for arthritic pain but it had no effect on the beuropaty, (. Now I take tumetic 95% curcumin, excellent for inflammation & other things but I haven't noticed it helps neuropathy). Benfotiamine in very high dosages has multiple benefits. One is that it promotes angiogenesis ( regrowth of arteries). While I was on the gett high dosage for many years I was not aware I had a 99% blockage in the popital artery, the main artery from the knee down the keg. It was discovered accidentally because I had no pain at all which is miraculous. The blockage was removed in 2019 and afterwards I have read about a study done on mice in 2006 that it promotes angiogenesis and the reason I had no.pain is because the high dosage I was on for years created colkatety arteries in my legs and that is why I had no pain. I have also read Benfotiamine is good for most autoimmune diseases. including fibromyalgia and Croans disease.
I have been for many years on high dosage Benfotiamine plus many other supplements that I experiment with. I also had an EMG test a little over a year ago that showed severe sensory neuropathy in my legs, mild motor.neuropaty, & very Mild neuropathy in my arms and also carpel tunnel. About two months ago I repeated tan EMG. My last EMG tests show although it had not been severe I no longer have motor neuropathy in the legs . The severe sensory neuropathy in my legs is now mild. I no longer have mild neuropathy in my arms and there is no carpal tunbel. The neuroligist who performed this last EMG is doubtful that zi ever had neuropathy because he said it is impossible for nerves to regenerate. I am also sering another neurologist next week to go over as ll these findings and see what he has to say.
I apologised for typos. It is late at night, early morning & I am writing this on a cell phone. But I wanted to share this important information with you.
Also Sulbutiamine is another fat soluable analog of Viramin B1. It is capable of entering the blood brain barrier whereas Benfotiamine can not. I have found and studies support this too can help neuropathy but more studies have been performed with Benfotiamine.
(Mumbai Maharashtra India)
Finally! My feet are returning back to normal. Getting off the B vitamins helped within a months time. Started taking Benfotiamine, a lipid-soluble form of thiamine (vitamin B-1). I have been taking if for about 3 weeks, 600 Mils, a day. I now have feeling in my feet again!
I had PN BAD in both feet. After several tests doc told me to stop the B vitamins. B6 in excess can cause PN. I quit the B vitamins and started taking Benfotiamine and after a month my feel are returning to normal! I can finally feel my feet and the tingling is almost gone. Thank goodness!!!!
Some people cannot metabolize B6 efficiently. I'd quit taking them asap.
My mum had severe pain, pins and needles, numbing, throbbing and tingling in her feet whenever she would try to sleep for about 20 years. I wanted to help her, so I looked it up online and found that vitamin b1 would help. Within a few days of supplementing with 1 vitamin b1 100mg capsule daily her pain is gone and she sleeps much better.
The peer reviewed studies found on pubmed.org clearly indicate benfotiamine's superiority over regular thiamine (B-1) for treatment of neuropathy. They also indicate a dose of 300 mg twice per day (total of 600mg) was more effective than half of that dose.
I have been suffering from peripherral neuropathy for over 2. 5 years now. Being tired of not finding relief at night, I came up with a solution that works for me. In my garden, I grow Bulbine (very prolific and similar to aloe vera). Since my feet were burning, I thought it might help putting it on my feet. The burning stopped until the gel dried. So, I place several stems of the bulbine between sulifane wrap and roll a rolling pin over until all the gel is squeezed out. Then I wrap my feet before going to bed. In the middle of the night, I have to take the wrap off, but the burning and tingling is minimized greatly for the entire night.