I was waking up in a panic daily, and SAMe stopped that for me, six years ago. But now, I guess I've outgrown it, because I have the physical (not emotional) sensation of anxiety, with such bad muscle tension in the front of my neck, that I am in physical pain for days at a time. SAMe is awesome for depression (except not for bipolar type)! Just watch, years down the road, as you might need to stop the SAMe. Also, whenever there is anxiety due to PMS, the cure is magnesium! And maybe calcium too, but I try to get calcium in my diet instead of supplementing. It is really hard to get enough magnesium in your diet however, what with the all the heavy metal toxicity, and with the way grains are processed today. Magnesium citrate and oxide are the best forms, and capsule form is by far the best way to insure that you are digesting it, unless you don't mind chewing up the tablets.
A few days before my period, I often find myself getting extremely anxious and paranoid. The same thing happens on day 5 of my period.. Not sure what is happening to my hormones, but I don't like it! I have discovered that a 200 mg of Sam-e will immediately stop the anxiety and paranoia. I still feel quite emotional up until the day I get my period, but it is way reduced with sam-e. Great supplement. I don't take it every day, just when necessary.
My husband had a habit of waking up at 2:00am in terrible anxiety every night. The rest of the night was toss and turn, toss and turn. I started him on SamE and overnight, the pattern ceased. Now he loves it and takes it every night. No more insomnia, no more anxiety, no more depression. Good stuff!
In the fall when the time changes, I often have a very difficult time with anxiety and depression, especially as the holiday season approaches. After being on Effexor for a couple of years, I decided I needed to find a natural solution as I was tired of always feeling 2 steps behind. I experimented with the supplement SAM-e and discovered that it worked wonders fairly quickly. I also realized that some brands are better than others as it is a very unstable molecule. I took the lower dosage 2x a day for about a month. At that point I had to stop taking it for a while because it appeared that my brain chemistry had corrected itself and I no longer needed supplementation. Now I take it as needed, which is about 1 pill every few months. I hope others coming off the anti-anxiety medication will give this supplement a try. It was a wonderful discovery! By the way, doctors in Europe prescribe this remedy more often than prescription meds.