For those suffering from anxiety and depression, please investigate the condition known alternatively as Pyroluria, Kryptopyrrole and/or Mauve Factor. Debate is raging as to the underlying cause of this metabolic disorder, but the body loses massive amounts of B-6 and Zinc, as well as the omega-6 acids. Moreover, copper begins to build up to toxic levels in the body, causing everything from depression to anxiety to seizures to schizophrenia. The degree of symptoms has everything to do with individual biochemistry and the degree of essential nutrient deficiency. The treatment is simple: high-dose daily suplimentation with niacinimide, B-6 (in the form of B-6 and P-5-P), zinc, manganese, magnesium, chromium, biotin and omega-6 in the form of evening primrose oil.
PLEASE NOTE, however, that this suplimentation should NOT be done without blood monitoring by a qualified medical practitioner. The doses required to see results are extremely high for each of nutritional components, and poisoning can result, particularly In the case of zinc. Moreover, a patient can reverse copper toxicity to the point of too-low copper, which results in its own, unwanted Medical complications.
This metabolic "disorder" is seen in 85% of all autistic spectrum individuals. It is speculated, in this case, that heavy metal poisoning initiates the oxidative stress that, in turn, results in pyroluria. The resulting low B-6 levels result in the inability to properly manufacture serotonin, the "happy nuerotransmitter". Thus, a myriad of psychological "disorders" can result. Conversely, the depleted zinc levels manifest themselves in the gut, leading to coeliac disease and other Malabsorption disorders, as well as leaky gut syndrome. This, in turn, allows various fungi, like candida, to thrive in the gut and, later, the entire body. This, in turn, leads to various types of cancer later in life.
This same biocycle occurs in non-autistic individuals, but to a lesser (slower) degree. Thus, testing for and treating pyroluria involves more than "just" treating anxiety and depression.
Those properly treated have experienced nothing short of miracles. But do note that it can take up to 12 months (although most see some improvement after 3-4 weeks and most see significant gains in 3-6 months) to restore the body's proper balance and that treatment must be adhered to each and every day, for the remainder of one's life, barring any new discoveries as to the underlying cause of pyroluria.