
One of the concerns that people have with using Melatonin 4 times a day for covid or other viruses is that, because Melatonin is used to help with sleep it is presumed to make you too tired during the day. I will share some of my personal experiences with that.
When we had covid back in January we all used high dose Melatonin (thanks to Art who kept us informed about the protocol! ) I used it on everyone in the house - ages 9 to 83, based on weight, as Dr. Neel recommends. We took it 4 times a day.
My 83 year old mother in law with dementia did not know what the pills I gave her were, I just added them with her other meds and supplements. She was not symptomatic of covid, but we were using it to try and prevent covid since others in the home had it. (I think it worked, or at least helped! She never got sick, but did lose her sense of smell.) Anyway, her sleep/wake patterns were no different than when she wasn't taking round the clock melatonin. (She always takes it at night.)
It was hard to tell how it affected those of us who were actually sick. Sick people sleep more.
I take 15-20 mg of melatonin every night to help me with sleep (and it definitely improves my quality of sleep! )
Last summer, an hour after taking my melatonin dose, my daughter-in-law went into labor. I had an hour of sleep but woke up easily and drove an hour and 20 minutes to the birth center where she had the baby. I had no trouble driving and no trouble staying awake all night.
I had the opportunity to repeat the experiment last week. I had taken my 20 mg of melatonin and fallen asleep when my daughter went into labor. I woke up and stayed up the rest of the night with her and was able to see another grandchild born. (What a privilege! )
I cannot know how it affects others. But I can say that melatonin does not make it impossible for at least some people to stay awake after taking a significant dose. Certainly it would be wise to know how such a dose would affect you before driving a long way or using heavy equipment.
~Mama to Many~
Insomnia
Dear Gertjr,
Bless you. I am so sorry about the deep loss of your husband! 💔😢
Love,
~Mama to Many~
Insomnia

I tried Art's protocol over the last few days and it worked! I was so pleased. My husband passed away on Saturday and I was exhausted and really needed sleep, had finished all my Tramadol (needed to stop taking it anyway), and took 3 mg every hour, going to bed after the 3rd dose. Slept like a baby until the cat woke me up, then went back to sleep for another hour, 7 hours in all. After several nights at the hospital, this was such a blessing. The last 2 nights haven't been quite that good, but still better than I expected with having so much on my plate right now. Thanks, Art.
I have a bit of migraine pain today, so hopefully that's not the melatonin but the stress. I'm probably a bit dehydrated, too, so need to take better care of myself.
EC: We are so sorry for your loss, GertJr. Sending you much love.
Isn't it strange that they banned melatonin in England, Scotland and Ireland back in 1995? It's even more strange that they haven't allowed it after the thousands of studies that have been done on it since then worldwide. How archaic!
Perhaps now is a good time to start a petition in your country to legalize it for over-the-counter use.
Induce Dreaming

I have been taking Melatonin for 7 months now and originally started to have vivid dreams and now my dreams are much more gentle but amazing nontheless, and great sleep indeed ... I started with a cream of 50mg per night for the first two months then upped the dose to 100mg per night for 4 months then tried the 250mg SR capsules but I was a little woosy in the morning, so I stayed on the 100mg for another month and now I am almost done the bottle when finished then I will try 250mg SR again ...(SR) stands for slow release ;) eventually working up to 400 or 500 mg at this point the pineal opens up and you begin to experience the truth of who we are ;) those who have done the research already know this.
Hi Kenny,
Yes, there are people who can not tolerate melatonin as I have mentioned many times on EC, but the majority of people do tolerate melatonin as shown in many studies. Generally, as soon as you realize that there is a negative reaction to melatonin or you are not tolerating melatonin because of symptoms such as you described, it is probably a very good idea to stop using melatonin immediately rather than continuing. It is sort of like your body is trying to let you know that this is not compatible with you.
Art
Side Effects
Hi HisJewel,
Thank you for the feedback on melatonin!
What I have noticed is that some people can develop diarrhea from HDM [High Dose Melatonin], but in the few people I have seen or heard of this side effect, that delay, can vary from 3 days to 3 weeks. In either case, the delay makes it possible to use melatonin long enough to help achieve the desired result with Covid-19 and it may be possible to use melatonin for a very brief period even if diarrhea does occur in an attempt to have maximal effect on Covid-19. Stoppage of HDM seems to allow a fairly quick recovery from the diarrhea. I still feel that the combination of melatonin plus the addition of the Xlear Nasal Spray, suggest the potential for a quick recovery.
Here is a link to what I wrote about Xlear Nasal Spray and Covid-19 : Https://www.earthclinic.com/xlear-for-covid-recovery.html
Art
Cavity, Gum Soreness

A friend who takes high dose melatonin every night recently mentioned to me that she discovered that she had a new cavity forming on the side of one of her teeth.
She uses melatonin that dissolves in your mouth, so she decided to place melatonin at the site of the cavity with her tongue each night when she went to bed. She told me that within two months, the cavity was very significantly reduced in size, so she will continue to repeat this process until it is completely gone. She also told me she had an area of gum that was sore, so she told me she applied melatonin to the area of the sore gum, and she said the pain was gone in two days. This second aspect she is reporting does have studies to support that melatonin is healthful for the gums.
I was aware that melatonin is good for the health of the oral cavity, but I was not aware that it could reverse a relatively new cavity. When I looked at studies regarding melatonin and oral health, I found that melatonin is noted for use against or as a preventative for gum disease, but no mention as a cavity fighter. Here is a typical study discussing multiple health benefits of melatonin for the oral cavity, including bone regeneration, but teeth are not actually the same as bone :
https://www.sciencedirect.com/science/article/pii/S1607551X16301012
Here are some relevant quotes from the study :
' Oral cavity is affected by a number of conditions such as periodontitis, mucositis, cancers, and cytotoxicity from various drugs or biomaterials. Research has suggested that melatonin is effective in treating the aforementioned pathologies. Furthermore, melatonin has been observed to enhance osseointegration and bone regeneration. '
' Topical administration of melatonin has a positive effect on periodontal health and osseointegration. Furthermore, melatonin is particularly effective in improving the periodontal parameters of diabetic patients with periodontitis. Melatonin exerts a regenerative effect on periodontal bone and may be incorporated into of periodontal scaffolds. The cytotoxic effect of various drugs and dental materials may be countered by the antioxidant properties of melatonin. Topical administration of melatonin promotes the healing of tooth extraction sockets and may also impede the progression of oral cancer. '
As you can see from this study, melatonin offers many benefits to help maintain oral health, but the repair of new cavities is a new one to me.
Art
Montmorency Tart Cherries for Melatonin

This brand new study suggests that drinking 480 ml of Montmorency Tart Cherry Juice or taking capsules of the tart cherry each day had little to no health benefit in the parameters tested in the study. This suggests that Montmorency Tart Cherries are a poor source of melatonin.
Here is a link to the study :
https://pubmed.ncbi.nlm.nih.gov/35790450/
Here is a relevant quote from the abstract :
>>> ' Despite the potential benefits of antioxidants and melatonin, we did not find improvements in sleep time or quality, cellular health or BP in participants consuming MTC for 30 days, though BM decreased in capsule groups. ' <<<
This study implies that if you plan to get your melatonin and its known health benefits from cherries, that will not likely happen. Even if you are just looking for better sleep, the result is still likely to be no benefit.
Art
Melatonin and Blood Thinners
Hi Pam,
Yes, melatonin has blood thinning and anticlotting effects, so getting your doctor's approval if you are already on a blood thinner makes safe sense. Too much blood thinning is bad and can be dangerous. Some common supplements like vitamin E and Serrapeptase can have blood thinning effects also, so anyone who is already on a blood thinner should seek their doctor's advice if adding a supplement with blood thinning qualities.
Art
Insomnia
Gertjr, Sorry for the loss you are going through. Griefshare is a website that will send you free daily encouragement and information on how one processes and how it affects the body.
Many people avoid talking about grief trying not to cause more pain. Then it can be difficult, not feeling like you have someone to talk to about what you are going through. First and foremost stop all negative chatter in your head . Write positive things to say to yourself. I did well and I am well. Every day I celebrate how good life is, and I remember the good things . I have suffered depression and all that comes with it so I say this to encourage you as you transition to the next beautiful stage of your life. HIs Blessings, Charity
Insomnia
Gertjr,
I am very sorry for the loss of your of your husband.
I am glad that you found benefit with melatonin and I hope it continues to help you through this difficult time. You need good sleep to allow your body to repair itself after so much damaging stress. Good health to you!
Art
Insomnia
Dear Gertjr - I'm very sorry to hear that your husband passed away. You have so much stress to deal with but I'm glad to hear the melatonin is helping. As difficult as it is with so much to do, you will need time just for yourself - to grieve, to rest. You are in our thoughts. Take care ...
Insomnia
Hi Randy;
I'm from a city down the coast from you, Charleston. I really miss the ocean. It was easier to get enough sea salt there.
It appears that in your situation, there are paradoxes to negotiate. I've read that some people do have increased insomnia, anxiety, and other side effects from melatonin supplementation. It's been suggested that they may try a dosage as low as. 1-.3 mgs. I also have low cortisol, and insomnia from early childhood. Although I have tried so many substances for this; herbs, amino acids, exercise, and even medications; my best results have been from combining a low dose b-complex with a sublingual b12. There can be paradoxical reactions to them also, as some can relax and or stimulate the system. I suggest trying the b-complex made from foods. (unfortunately it's expensive) It may be only needed in smaller amounts. Try 1/2 tablet in the morning. ( I have it with an empty stomach, but it may be easier with food).
Also, try methylcobalamin sublinguals, (active-b12); because it enables the other b's to operate. A 1000 mcg. Tablet can be divided with a pill cutter into 4 wedges. It may be that only 250 mcgs. Is needed daily for sensitve individuals. I have also found that folate has been very helpful with depression, But it must be measured carefully according individual needs. I recommend methylfolate. It comes in 800 mcg. Tablets that can also be subdivided.
While there is the RDA of folate in supplements, some people with atypical depression have responded very well to extra folate. It can have mild stimulant properties for some people, so I suggest trying small amounts in the morning. (It is also good for sensitive gums and canker sores when dissolved in the mouth). I have found these supplements to also lower many types of inflammation that can deplete cortisol.
Peter,
Because of the serious nature of your wife's condition (kidney transplant & potentially related issues), you should be talking to her transplant specialist about the use of melatonin and here are a few studies that suggest that melatonin may be beneficial, which you can show to her doctor to give a little more information on the potential utility of melatonin in kidney transplant. I am not a doctor and this is well beyond the scope of information that you should be looking for on a forum that specializes in home remedies. Here are a few relevant links that her doctor can consider as to whether melatonin will be useful for her specific case. :
https://joe.bioscientifica.com/view/journals/joe/229/3/R129.xml
https://www.scielo.br/j/ramb/a/JZYNnhjCVYYNtFrtMxZ6kqK/?lang=en
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC7073605/
https://pubmed.ncbi.nlm.nih.gov/31446153/
https://pubmed.ncbi.nlm.nih.gov/30671880/
Best wishes to the both of you!
Art
Side Effects

For many years, I had trouble sleeping and took Melatonin and always felt groggy and a hangover from taking it, but since pot is not legal in TN, what choice did I have? And then all of a sudden, my whole system flipped and then suddenly I couldn't get enough sleep! Suddenly 8 hrs was not enough and I always felt exhausted! What a nightmare! Not saying the melatonin had anything to do with it, but it what I was taking and it scared the holy hell out of me!
Now I'm fighting diabetes and liver damage and thyroid malfunction which came on all of a sudden also and while I am overcoming that slowly but surely by alternate day fasting, cutting ALL wheat products out of my diet, and the old timey cottage cheese and oil (Flax, black seed & Hemp oil) medicine cancer cure remedy!
But I'm not my old self by any stretch as before I started taking melatonin every night and so am very leery about ever taking melatonin again! Besides it always makes you feel so tired and groggy and who the hell needs that when your 65 yrs old? Certainly not me! So the jury is still out on that one! The side effect of melatonin is it makes you drowsy and tired, and I need just the opposite of that!
Hi Katie,
I found 10 mg capsules on Ebay UK :
You may have missed my post about Xlear Nasal Spray for Covid-19, but these are the two main components I plan to use if I get Covid-19. Here is a link to that post :
https://www.earthclinic.com/xlear-for-covid-recovery.html
Here is a link to the product on Amazon UK :
If you can, get her started on the spray if you can get it from a local drug store. The post that I linked to above shows how they used the Xlear Nasal Spray, how often and what effects it had on the small group of patients.
Good luck to you and your friend!
Art
Side Effects

Regarding Melatonin Side Effects,
Melatonin was a big help in starting my fight to get well even with side effects.
I decided to reorder some more Melatonin, because I was glad that I had it on hand to meet a possible emergency during my coughing fits. As I mentioned I took about 100mgs of Melatonin for each of 3 days. I took 4 to 5 pills a few times a day and once at night. They were 5mgs each. No, my brand did not make me sleep or sleepy; however, I found that when I was ready to sleep they let me sleep at least an hour or two at night. The side effect I had was loose stools.
Some years ago, I had ordered some Melatonin from eBay. I am not sure why I bought them, I do remember reading a book back then that said it was good for stopping any further memory loss in its track. Anyway, this Melatonin product was from overseas, it was a powder, and a very high mgs per tiny scoop. I do not remember the company. I remember going to sleep that night and not waking up until morning. In the garbage it went. As I used to do all night prayer often and too much sleep would interfere with my work. The interesting thing is I do not remember having any side effect, only what it said it would do give me sleep.
The Melatonin that I had on hand when I was sick this month, I bought last year because Earth Clinic, Art and others posted Melatonin benefits for COVID 19.When I decided to buy more, I noticed that I needed to find out what "Other ingredients" are in each brand and kind of Melatonin. The company that I got mine from had at least 3 different kind of Melatonin mixtures. I did not want any artificial sweeter in mine so I was reading the labels. Then it dawn on me that perhaps one of the" Other ingredients" in the brand that I already had was what caused the side effect that I encountered. So please read the label.
HisJewel

Insomnia: My kids have a hard time sleeping at night. I've struggled for about 10 years trying to put my ADHD girl to bed at night. The older she became, the worse it was, telling me to "get lost" when I came in the room at 11:00 p.m. She would just continue on the computer and ignore me. It was very depressing. I had to sleep so I would just go and leave her alone. Her dad didn't help much. Rescue remedy! melatonin! I bought the chewable kind and used to give it to her when I was totally exasperated at 10 or 11 p.m. Now I give it to her at 8 or 8:30 p.m. and now she jumps into bed by 9 or 9:30 p.m. What a miracle! Why did it take me so long to figure that one out? She was sleep deprived for many years!
Where to Buy: UK
Hi Glennise,
This one ships to the UK:
You can get melatonin by prescription in the UK and any dose is better than no dose. If your Dr. will write a script for each of you for 5 mg capsules for sleep, that amount may hold you over until your order arrives.
Art
Side Effects
I definitely feel your pain. I had insomnia for years. Turned out it was gluten. (Yeah, I thought I'd tried eliminating it, but I guess I hadn't. If I get even a pinch of flour, ping, eyes wide open all night long.) Melatonin makes me loopy as well unless I take a tiny tiny dose. Also, if I do high intensity workouts sometimes that makes it worse, especially if I'm fasted.
GOOD LUCK and SWEET DREAMS.
Induce Dreaming
Can you express a little more on the relationship between melatonin and the pineal. Thank you.
Side Effects

Hi Manti,
I use to take melatonin, but stopped because of two side effects. One side effect was that it acted as a diuretic, so I really didn't get much sleep b/c of running to the bathroom. The other was very real dreams. It got to the point that I could not figure out if I had really had conversations with people in my dreams versus reality. Melatonin is actually a hallucinagen your body naturally produces. I guess when you add more of the chemical to your body, it coases you to dream more realistically.
Adhd

My son has been taking Melatonin for almost 4 years now. He is now taking up to 6 mgs at age 10 and he sleeps great and has had no side effects. He is ADHD and never slept well thru the night before melatonin. It really makes a difference in his behavior as well. I would strongly recommend it.
Insomnia
GertJr,
Try this combo for better sleep :
https://www.earthclinic.com/art-solbrig-insomnia-protocol.html
Art
Side Effects
Where to Buy: UK
Thank you for replying. Delivery from Piping Rock was super fast, it only took 1 week from US.
Where to Buy: UK
Use vitamin d it is the sà me at over 500 u per week if sick help with more until it abates and go back to th 500 u again every week
Induce Dreaming

Remedies to Induce Dreaming: I usually don't dream, but I have found out that whenever I take Melatonin to sleep, I have the most vividly realistic dreams I could ever imagine.
Insomnia

I have found that Melatonin is extremely beneficial in helping me get to bed. This is on top of the Seroquel that I already take, which is dosed at 100mg. I usually start off with 3 mgs. of Melatonin, and if that doesn't help, I take another 3 mgs. (because the supplement that I take only comes in 3 mg. tablets).
The usual recommended dose of Melatonin to start with is 5 mgs., and then take it from there. This is a extremely effective supplement, and I would recommend it first before anything else.
Insomnia

I suffer from adrenal fatigue (low cortisol) and atypical depression so I decided to try melatonin the last couple of nights to try to give my adrenals some well needed rest. Typically I only average between 5 to 6 hours of sleep per night but the last couple of nights I only got about 3.5 hours of sleep. First night I only did 1mg and last night I did 2mg and with upping the dosage I still only got 3.5 hours of sleep. Why am I getting less sleep taking melatonin? I have read where it can have the opposite effect with some people and I am wondering why this happens? Anyone else have the same experience?
Insomnia
I have read a report recently that talks about the mixed findings with melatonin. It's hypothesis is that it relates to the circadian rhythm and should be taken at least 2 hours away from food. It is suggested that one might try to eat dinner earlier, and/or skip breakfast so as to avoid glycemic interference.
Insomnia
I, too, had little success with melatonin until Deirdre (I think, or was it Art?) mentioned large doses. I now take 10 mg an hour before bed and 10 mg of timed release melatonin just before bed. I also take niacin (for cholesterol, but the flush helps me sleep), only 500 mg, every night along with the timed release melatonin. I've been sleeping much better since I started this protocol. I still don't sleep great, still wake up off and on, and sleep only for about 5 hours per night, but it's so much better than it was. What does are you taking, Jake? Be careful, tho, since melatonin can make your stool loose. With my ibsd that's a real concern, but this dose I'm taking seems to do well.
Insomnia

Melatonin has been a God-send for me. I'm a terrible insomniac, especially on business trip. I don't like druggy meds, so I tried melatonin several years ago. About 20 minutes after taking one I drifted quite naturally off to sleep. Now, I still take them occassionally, but usually just the thought that they're in the medicine cabinet is enough to relax me to sleep! Melotonin induces the body's 'down time' mechanisms which night owls like me tend to inhibit. Now I know to relax, read a book, watch tv, or just 'chill' about 20 minutes before bed, this behavior allows the body to naturally produce it's own melatonin and drift peacefully to sleep. - sleep tight!
Melatonin and Anti-Rejection Drugs
Attn: Art from California
My wife is on anti rejection drug for kidney transplant and blood pressure medication.
She has trouble sleeping and told me Melatonin can not taken. Please let me know is that the case.