The Extensive Health Benefits of Methylene Blue

My name is Lisa. I am 43 years old I want to share with you an experience with Methylene blue. I have been using it for 5 years. it is effective on depression and calm anxiety. I tried 2 types of Methylene blue -- powder as well as liquid. The liquid was much expensive in comparison to the powder but both have same results. For 2 years I have been using Methylene blue powder form. I was purchasing it from cztl.

Have you checked your iodine levels? Low iodine can occur while detoxing and should be added…low iodine can cause heart arrhythmias.

If you are concerned about stroke then learn about DMSO. Miraculous and does so much more. ( Just learning about methylene blue…0

"you must hold your breath while nebulizing--do not inhale the mb" - this is NOT correct. Read this doctor's report

https://dr-deepak-golwalkar.medium.com/treatment-for-covid-19-using-methylene-blue-d23fc5a31a4d

IODINE!!!

If you supplement a good quality vit.c with M blue, the whites will not turn blue.

I am having a blonde moment with math. I got a high quality 30ml (1 oz) bottle of Methylene Blue with 300mg of MB in it. 1 drop was .5mg so I did that for 2 days with 1000 C. My eyes did turn a bit blue. Most of the calculations are for 2.3% and Ted's 1 gram powder to 1000cc.

So Help Please. It would be so beneficial to know how many mg or mcg makes up 1%, and/or .1%. AND how to get 30ml of 300mg to 1% since it's not a powder.

What's crazy is seeing doses of 15mg (which would make my eyes navy blue ; ) online.

Any help is greatly appreciated.

Hi Lynn,

I just finished reading an article by Dr Mercola who interviewed a Methylene Blue (MB) researcher. The researcher said there used to be pills of 60 mg MB that were used for UTIs. He put his mother on a dose of 1mg per kg body weight a day. He generally recommends 0.5mg/kg up to 1mg/kg (pharmaceutical grade as any others have heavy metal contamination) taken with 1000 mg of Vit C in the ascorbic acid form as it reduces the MB to be bioactive.

I just started taking 3drops in about 6oz of water per day, working up to a dose that I can feel better with. My rough calculation is that with 10mg/ml of MB, my weight of 118 in pounds becomes 53.5kg, divided by 2 for the .5mg/kg (or you can multiply by .5, your choice, same answer) becomes a good dose of 26.75mg MB which is then 2.675ml, which then is slightly over 1/2 teaspoon (conversion charts are amazing). It will take a lot of drops to get to that dose! But if a lower dose works, I'm happy.

Hi Lynn,

My neighbor and some of her relatives had trouble with recurring UTIs, and she found a probiotic that is sold on Amazon to stop this in everyone who has tried it. We also had a friend who had the same problem and was very ill, so we gave her several packages that my neighbor had on hand, and she is now completely well, as long as she takes the probiotics. She thinks it is worth the cost to stop getting the UTIs. It might be worth a try.

https://www.amazon.com/Medix-Synbiotic-365-30-Capsules/dp/B088VLBX4T

Best wishes!

check out Lifeblud, canadian company, they have it unlabeled on website with blue question mark, a bit pricey but the real deal

Methylene Blue for Prevention of Chronic UTIs:

I bought MB from Botany Biosciences. Bottle states 10mg/ml. I weigh 130 pounds-any suggestions for dose? Do I need to take Vitamin C to prevent staining as others suggested? I am tired of taking antibiotics every 3 months-and has affected my gut health. Thank you!

I have purchased 20gm Methylene Blue. I presume too make 1% solution I use

1gm to 1 litre liquid?

1% of that to make 0.1% solution

What liquid, distilled water or alcohol should I use to do this?

Can anyone help me with this please?

I have tried 2 compounding pharmacies in Toronto- they say need prescription. If anyone has a compounding pharmacy that will make the 1% solution, I can send you money to buy for me....thnx

I am looking to find a source for MB in Toronto. Any suggestions? Many thnx

I am an intermittent catheter user, therefore, I have chronic bladder infections. Ever since I began using Methylene Blue I have stopped getting UTIs. I use Methylene Blue 1% solution. The normal dose is 10 drops in water morning and night. I only need 2 drops morning and night. I use a straw to drink it so my teeth won't turn blue. It has the added benefit of stopping my candida symptoms.

Having said this, I am also very careful about what I eat: no sugar or fruit of any kind. I don't use any artificial sweeteners. I avoid wheat and other grains. I eat canned beans, eggs, fish, chicken, vegetables, and brown rice. I have to avoid nuts.

Allgood, what do you mean by "you must hold your breath while nebulizing--do not inhale the mb--will hurt your lungs." The whole idea of nebulizing is to breathe the atomized liquid into the lungs. So what's the point of nebulizing methylene blue, if you "must hold your breath" and "do not inhale"? I don't understand.

I just read somewhere that too much of MB has the opposite effect. I have also cut and pasted from a nootropics page what happens with co q 10 ...

"Methylene Blue donates electrons in the electron transport chain in your mitochondria. So experienced neurohackers suggest avoiding CoQ-10 or idebenone when using MB because it seems to make Methylene Blue much less effective."

from: https://pubmed.ncbi.nlm.nih.gov/27031833/

DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis

Abstract

Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various inflammatory conditions as well as for cancer. Despite its widespread use, there is a paucity of data regarding its safety and efficacy as well as its mechanism of action in human cells. Herein, we demonstrate that DMSO has ex-vivo anti-inflammatory activity using Escherichia coli- (E. coli) and herpes simplex virus-1 (HSV-1)-stimulated whole human blood. Specifically, we found that between 0.5%-2%, DMSO significantly suppressed the expression of many pro-inflammatory cytokines/chemokines and prostaglandin E2 (PGE2). However, a significant reduction in monocyte viability was also observed at 2% DMSO, suggesting a narrow window of efficacy. Anti-inflammatory concentrations of DMSO suppressed E. coli-induced ERK1/2, p38, JNK and Akt phosphorylation, suggesting DMSO acts on these signaling pathways to suppress inflammatory cytokine/chemokine production. Although DMSO induces the differentiation of B16/F10 melanoma cells in vitro, topical administration of DMSO to mice subcutaneously implanted with B16 melanoma cells was ineffective at reducing tumor growth, DMSO was also found to block mouse macrophages from polarizing to either an M1- or an M2-phenotype, which may contribute to its inability to slow tumor growth. Topical administration of DMSO, however, significantly mitigated K/BxN serum-induced arthritis in mice, and this was associated with reduced levels of pro-inflammatory cytokines in the joints and white blood cell levels in the blood. Thus, while we cannot confirm the efficacy of DMSO as an anti-cancer agent, the use of DMSO in arthritis warrants further investigation to ascertain its therapeutic potential.

Have been using methylene blue for 2 months now with great results. I am using a teaspoon of baking soda about an hour after meals in an effort to get off of Prilosec. In doing this I have noticed that my urine is no longer blue. Anybody else noticed this after using baking soda with methylene blue?

Using Methylene Blue is not just a hypothesis.Regarding using methylene blue(MB) against COVID-19 ARDS, there is an Indian doctor, Dr Deepak Golwalkar, who, as a pulmonologist and lung specialist, has been using his nebulized/sublingual MB treatment for quite a while and with great success for his pneumonia patients and for his COVID-19 patients with ARDS. Here is his website, which details his treatment:

https://medium.com/@dr.deepak.golwalkar/treatment-for-covid-19-using-methylene-blue-d23fc5a31a4d

Interestingly, Dr Golwalkar also uses exactly the same concentration of MB for nebulizing -- 0.1% methylene blue -- which is the same concentration that Ted from Bangkok recommends.

The only drug known to inhibit the excessive production of reactive species and cytokines is methylene blue, a low-cost dye with antiseptic properties used effectively to treat malaria, urinary tract infections, septic shock, and methaemoglobinaemia.The relatively poor efficacy of anti-cytokine drugs is explained by the fact that they act on one or a few of the dozens of cytokines involved, and because other mediators of inflammation – reactive oxygen and nitrogen species – are not targeted. When produced in excess, reactive species cause extensive cell and tissue damage.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728423/

This is NOT correct, please do not follow this as it is the dilution instructions for getting .1% from a 1% methylene blue solution NOT 2.3%.

To get .1% of a 2.3% solution you add 1 part of the MB to 23 parts of the diluting liquid (distilled water is preferred, it seems). I saw a video where someone added 1ml of MB to 23mL of distilled water. I don't remember how many drops of that solution they said they take, that is what I am looking for here and it hasn't been answered in the first 50 comments =(

Art,

As of 7/13/2018, Your link goes to Methyl Blue, which is NOT Methylene Blue. As you all know, in chemistry, the EXACT NAME matters. Be sure you are looking up "methylene blue".

HI

I really need methylene blue since I have a genetic disorder(Methemoglobinemia)

But I cant seem to find a way to purchase it because it is not available to buy in my country.

Is there any way you can help me with that. Thanks

Does the MB stain white porcelain bathtubs at that concentration? Thanks!

Please don't take any grade other than pharmaceutical! Methylene blue can be contaminated with heavy metals or other contaminants if it is prepared without human consumption in mind. If you go to a local compounding pharmacy (in NS the medicine shoppe is one I've had reasonable success with) they can help you out. At the pharmacy, you do not want the ophthalmic solution, as it is not tested safe for consumption either. They may be confused and initially ask you for a prescription from a doctor, but you do not need one. Methylene blue is a bulk chemical, not a drug, and as such you are left on your own in finding the appropriate grade to consume that will not hurt you over time.

Research indicates Vitamin C may inhibit Methylene Blue's killing of Candida

Ted's advice on many areas of health have been of great assistance to me. I became interested in trying Methylene Blue for attacking my systemic Candida, and did some additional research. I came across a study that indicates that taking Vitamin C with MB may decrease the effectiveness of its impact on Candida. The research is found at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780517/

The relevant quote is halfway through the abstract: "... sensitivity of Candida cells to MB could be rescued upon the supplementation of ascorbic acid, an antioxidant." In the context of the abstract, this "rescue" seemed to be contrary to the intent of killing Candida cells.

Therefore, I began to take MB 1 drop twice a day (along with BHT), but taking ascorbic acid at least two hours later. My reasoning was taking such a small dose had no risk of side effects (coloring eye, etc.), but that any potential impact on Candida would not be lessened by the ascorbic acid.

I understand that Ted is not currently up to responding, but am hopeful that this information may help others, if you or someone may take a look at it and comment on how to take MB and Vitamin C (perhaps 2 hours between the two?).

Hoping this may assist others in recovery from Candidiasis;

Sincerely, Susanna

All the formulas for breaking down Methylene Blue 2.3% caused nightmares of high school math & science, resulting in an Excedrin PM headache lol. I took the info everyone provided and it averaged to be 1 part 2.3% MB : 22 - 23 parts distilled water.

Still afraid to try it, I called a friend of a friend who's a chemist - he said 1 part MB to 23 parts water. (The K--don is 2.3% water solution, zinc free.) I hope this helps!

METHYLENE BLUE, I have been using MB topically on benign skin lesions, the doctor had been freezing them off, but they eventually come back and the freezing is painful. So I just applied the 2.3% (fish stuff) directly on the spots. They take up the dye, and dry up, I reapplied it to the larger spots a few times, the small spots just healed up very fast. skin is looking great, no pain.

Methylene Blue Dosages

Reading here and elsewhere all the discussion about MB, could be helpful to put it all in perspective. I ran across also an article (link posted below) that helped with some aspects of the questions. The accepted doses for various conditions cover a range of three orders of magnitude, ~ 50 mg to as little as 50 micrograms. Even if a person determined the dilution necessary for the final dose it might not be the best amount for that person. Genetics, epigenetics and the mediation of microbiomes on any medication does make fools of MDs who are inflexible. How to get a particular dose? I have several droppers from herbal extract 1 oz bottles. One is graduated in 1/4 ml increments.

So, one ml, close 2/3 of that dropper, of the fish tank solution of 2.3% methylene blue is gonna be about 23 mg methylene blue. Just now tried with water and found 8 drops ~ .25 ml. 1 ml water is 1 gram. With MB drops the equivalent could be different because of surface tension and viscosity but that I will try later. Rough estimate at the moment is 1 drop/30 mg of 2.3% MB solution contains ~0.7 mg MB. If you want a dose in that range put n drops into a glass of water.

http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.476.2623&rep=rep1&type=pdf

For fibro...in my mind this is a toxin illness, in that you have toxins you can't get rid of. Someone mentioned wonderful results with pulling teeth (assuming they were amalgams.) Also many people with MCS have ongoing or former fungal exposure (water damaged buildings) which their doctors know nothing about (there is a lot on the web) and some have ongoing fungal infections. I had one friend who got over her MCS (and she also had CIRS, the inflammatory response to the pathogens in water damaged buildlings) after treatment with ampohtericin B for a fungal infection, after she had gotten out of environmental exposure. These "syndrome" things can take a very long time to track down, but take a look at what poisons you might be retaining and how to get rid of them. Many of us have had to live outside for a number of years, to get mold toxins out of our systems. There are now a few doctors who specialize in the people who have the genetic haplotype that cannot get rid of mold toxins. (Illness now called CIRS.)

Recent research has been published about methylene blue : Common antioxidant could slow symptoms of aging in human skin. The study was published online in the journal Scientific Reports on May 30,2017. The article is available on several web sites.

Is there a use-by date for Methylene Blue? I bought a 250 ml. bottle about 12 months ago.

WARNING!

In reply to Leanne (Ca),

Topical methylene blue is difficult because it stains your skin blue and for that matter, some painted surfaces and stone such as marble so you have to be careful handling methylene blue. If the topical application is for fungus, borax might be worth considering or the borax and diluted hydrogen peroxide which do not stain the skin.

Art

What about putting it on the skin. I am just hearing about the benefits of MB for skincare. Thanks!

I haven't read the instructions, but I am very familiar with vitamin C. Usually vitamin C means Ascorbic Acid. Sodium ascorbate is also called vitamin C - as are all the ascorbates, but the ascorbic acid has been reacted with in this case Sodium and is fully buffered so a neutral pH. This will react different chemically to straight ascorbic acid. In the instructions did they mention which form to use?

Greetings. I'm on the candida protocols from book. I had to buy 1% MB, rather than the 0.1% called for. I thought I had figured out how to dilute but also confirmed where Bill addressed the problem for another person.

I followed as he states: 1 part by volume of 1% to 9 parts water. I used tablespoons, 1 to 9. Then I thought I understood that would be my jar supply to work out of. I then did 10 drops (protocol amount) from that new mix and added water for drinking. Added 1/4 tsp sodium ascorbate as directed whereupon he says it should go from blue to clear. It did not clear. I'm guessing maybe he expected my powder to be same strength as his powder...or something like that? My powder is 'crystalline' and states 1/4 teaspoon is 1112 mg vitamin C as sodium ascorbate and sodium 137 mg. I guess I thought powders would be one basic same 'strength'. I added another 2 teaspoons once before hoping that would help but it did not.

I could certainly be 'one sandwich short of a picnic' in my reasoning so please help me get un-stumped. I'm very new at this stuff as well as having 50 varieties of foggy, soggy brain. Thank you for sharing your power around the universe.

Goofy Genie

Maybe I didn't make it clear in my previous writing,

you just put the 100mg MB into a graduated container and add distilled water to fill up to 100cc(mL), the total volume is to be 100cc when completely dissolved (which include MB & water of course).

I'm new to this site, so I just saw your message very late & realized that, as I said above in my writing, there is quite a confusion in % of MB.

You can calculate the percentage stuff using the same formula: % = g/cc -> cc = g/%:

Since you know g=0.1(100mg), %=0.001,

cc = g/% = 0.1/0.001 = 100.

So you'd make 100cc(mL) of 0.1% solution of MB.

Warning: in above formula 'g' must be in grams and % must be in "fraction" as the calculation shows.

I know it's way late, I guess you already have answer, but I see so many confusions about % of solution, so here it is for those still confused:

% = g/cc, what you have 1.943g/100cc = 0.019 =~ 2% solution.

To make 0.1%, add 19 x water to it.

But better way of using it is use what Bill said:

. just use 1 drop and consider it to be 20 drops of standard 0.1%.

. add 20oz water to it. Now your 20oz is equiv. to 20 drops.

. If you take 1 oz, you just took 1 drop,

take 2 oz, you just took 2 drops, etc...

Good luck.

I also thought I had Lyme disease. It turned out that I had an ongoing toxic mold exposure, that nearly killed me before I found out what it was (and not from a doctor) and got out of my house that had a hidden water leak. Lyme and CIRS (toxic mold illness) have extremely similar symptoms, and common mis-diagnoses are CFS, Fibromyalgia, and any other "syndrome" disease.

Anyone whose doctor says "it must be a virus" yet it never goes away, should go read survivingmold site. Water damaged buildings are common but the vast majority of physicians are not cognizant that 24% of the population has a genetic haplotype that is susceptible to the toxins. So only 1/4 of the people in a water damaged building will be extremely ill, and the other 3/4 either not ill or only with niggling minor illnesses. Well worth a look for the CFS/Fibro people. If I hadn't found out it was mold, I'd be dead.

MB Dilution: To arrive from a 2.3% solution to a 0.1% solution you simply add 23 units (drops, oz, etc) of distilled water for every 1 unit of MB. I used a glass eye dropper container. Add 20 drops of 2.3% MB, then add 460 drops of distilled water.

5 drops? ...I am taking 40 drops of Methylene Blue and do not see much of an improvement, but I am taking it only for 3 weeks so far.

I found that methylene blue works great for chronic fatigue. It was like someone hit my on switch. My energy level and thinking improved drastically and I was easily able to give up caffeine. However, the reason why methylene blue was able to work so well for me is that my chronic fatigue was due the fact that methylene blue treats mitochondria damage, and I have mitochondria damage from taking Cipro. Never take Cipro.

Methylene blue is from an aquarium supply shop or online. That is how I buy ours.

Ted here on earthclinic says that to balance and treat fish and tanks it must be high quality and effective. I have found this to be true. Janet

Hello

I am trying to find a top quality Methylene blue product for my mum. Can anyone recommend one and give some guidelines and maybe other products to take with it etc

Nadine,

Here is how we do it. We use that brand. The bottle should have powder in it. I fill the bottle to below the rim with spring or distilled water cap it and shake. Do this on a paper or glass plate it stains. Citrus cleaner or lemon removes stains. In a two oz. Dropper bottle I add 4 stoppers of the concentrate then I add water to that carefully it loves to overflow leave room to put dropper back in. It makes .01 % solution. Then you can use whatever your remedy calls for. Do not forget to add c with it when you take it. Janet

I bought kordon. methylane.blue and wondering how to dilute this down seeing that it is 2.33 %. I am not good with percent as a lot of people may be.

Edward,

If you are concerned about the quality of the methylene blue you are considering using for your mom, you can purchase it through a chemical supplier like Sigma Aldrich where they will have a certificate of analysis, a spec sheet and a certificate of origin so you know exactly what you are buying and its purity. It will cost a little more and won't be as easy to get, but you know exactly what you are getting.

http://www.sigmaaldrich.com/catalog/product/sigma/m6900?lang=en®ion=US

Another option is to speak to your mother's doctor about it and see if he/she will write a prescription that can be filled at a compounding pharmacy to your doctors specifications.

You will have to do some research on your own to get a better understanding of how MB may be helpful for neurodegenarative diseases and what dose would be best in your mother's case. MB has a good safety profile and probably a very good safety profile at the dose your mother would likely use.

PD has multiple forms and one form is directly associated to longer term pesticide exposure while others do not have this association. Some progress slower than others.

In the mean time, you might look into vitamin D as it relates to Parkinson's Disease. There are many studies available on PubMed that suggest that the population in general is low on serum 25 (OH)D, but even lower among people with Parkinson's Disease and that the lower the serum 25(OH)D, the worse the symptoms. A couple of the studies go so far as to say that the proper serum level of 25(OH)D may slow disease progression and help protect neurons in the brain.

There are many supplements that show benefit for people living with PD. I am currently compiling a lengthy list of about 50 of these supplements and gathering information on them trying to see which ones are most likely to have actual benefit in humans. Many supplements have only been tested in rodents and consequently would fall lower on the list. It is a work in progress and will take me sometime before I am finished. Having a very good to excellent safety profile is a very important consideration for me because that will improve the odds of having a doctor approve a supplement for a patient.

The topical magnesium oil is frequently noted for helping to relax stiff or cramping muscles in PD and is readily available at many health food stores and on the web. It also has other health benefits and can build up the bodies supply of magnesium while limiting the potential for diarrhea.

There are many supplements that show potential to be of use in PD, but you'll have to do your research and determine what will be compatible with for your mother.

In any case it is important that you get approval and supervision from your mother's doctor before using any supplements to make sure that they are compatible with the prescription meds that she is taking.

Art

You have to be able to think outside the box.

All of the questions you asked can be answered by doing some online research. I've been an EC devotee for many, many years, but I never stop doing my 'homework'. I read, read, read *everywhere* online.

With natural remedies, quite often, there isn't a real answer to 'why' something works--it just does.

How can something from a pet store for fish tanks help with parkinsons? What is this methylene blue? Is it safe to take? When I read the post that others have written, there's no reply or answer will I get an answer? How am I supposed to get my mom to take something from a pet store it sounds crazy. I hope someone has good answers for this post. Please help.

I use two drops in a shot glass of distilled or spring water.

I was looking for a very pure MB solution - not one found at at aquatic store - which are supposedly loaded with arsenic and other impurities So I found a supplier today here in the USA and would like to include her email answers on the purity of their product. EC, hope this is OK.

Debbie replied
May 17,10:24pm
Hey,

We always vet products with independent testing. Here's the test result for the current batch of methylene blue: https://www.bluebrainboost.com/wp-content/uploads/2016/02/methylene-blue.pdf

It's over 100% when it's more pure than the reference sample from Sigma Aldrich. The actual purity is probably between 99-100%.

--
Debbie Boykin
[email protected]

Donna C replied
May 17,10:11pm
Thank you, Debbie!

Yes, I do have one more question - can you tell me the percentage of purity of the powder you use to make it?

Donna

Debbie replied
May 17,10:04pm
Hey,

Thanks for reaching out.

Our 10 mg/mL solution is 1% methylene blue.

Let me know if you have any other questions and I'll be happy to assist!

Regards,
Debbie

--

Donna C sent a message
May 16,5:08pm

Message Body:
Hi,

I am interested in your meth. blue. Can you tell me what % your solution is....specifically, I am looking for a 1% solution.

Thank you!

Donna