I mixed bloodroot powder with aloe vera skin lotion and applied it topically on AK lesions for a week but it did not seem to trigger any healing reaction. I would try it again however if needed, because I didn't really give it a fair chance: I did not keep moist lotion against the skin under a bandage at night which might have possibly increased effectiveness. Since there was no immediate result I switched to treatment with apple cider vinegar which I described in a different post.
I was surprised to find that bloodroot lotion temporarily stained the rough non-pigmented AK patches on the surface of the skin to create a sharp contrast with the surrounding skin so that it became clear exactly where the lesions were located and where the boundaries were. For the first time I was able to see that I had at least 10 distinct AK's on the surface of my scalp ranging from the size of a pinhead to the largest with 5/16" diameter. However bloodroot may not be necessary for this because the staining effect for AK location purposes might also be achieved with a more common herb like turmeric mixed with lotion.