Pet Medication Side Effects & Drug Detox


Posted by Debbiehd (Dayton, Ohio) on 07/06/2014
0 out of 5 stars

I applied PetArmor to my Lab about a week ago. He started scratching violently and I thought it would wear off. He did not even have any fleas--I was using this as a preventative. What should I give him? He is miserable and also has developed a lump under his leg, one of the places he is itching severely. I just started researching PetArmor and there are some lawsuits because their pets died. What can I do to help him? This is such stupidity that you can't even trust what you buy at the store for $40 or $50 dollars. Can anyone help me with this? Should I give him Benadryl? How much? He weighs 115 lb. Thank you.

Replied by Theresa
Mpls., Mn

Hey Debbiehd!

Sorry to hear about the side effects your lab is experiencing.

If this were my dog I would bathe him immediately to remove as much of the substances as possible from his skin and coat. Use cheap human shampoo and follow it up with an apple cider vinegar rinse to neutralize any soap residue.

Next, I would have him ingest an internal cleanser such as bentonite clay or activated charcoal; these should be available at your local health food store or whole foods co-op. Mix a teaspoon or so into canned wet food and do this am and pm for 3 days.

Benadryl would not hurt, I would go for it were it my dog, and also I would consider using OTC anti-itch creams with cortisone. This is not for long term use, but just to nip the reaction he is having in the bud.

It wasn't clear if you used the regular Pet Armor or the Plus - the plus has fipronil and S-methoprene. The S-methoprene leaves the body in about 5 days, while the fipronil stays longer. Support your boy by making sure he is taking in plenty of liquids - this may mean giving him wet food for the next week or so to ensure he is taking additional liquid in besides water.

Prescription Eye Drops

Posted by Ricky (Hammond, La) on 03/23/2012
0 out of 5 stars

My 5 year old Pekingese developed corneal ulcers on each of his eyes due to early drying of his tear ducts, I brought him in to be seen. He was prescribed an antibiotic eyedrop and a pain relieving eyedrop. I administered his medication as instructed by the veterinarian. He then became lethargic and refused to eat or drink anything, he began vomiting clear liquid which resembles saliva and had diarrhea which looked like brown vomit. Jasper passed away 2 days after beginning the medication he was prescribed, this may be coincidental but I would like to know for certain.

Pain relieving eye drops: Flurbiprofen Sodium Opthalmic Solution USP 0.03%

1 drop in each eye once a day

Antibiotic eyedrops: AK-TOB Tobramycin Opthalmic Solution USP0.3%

1 Drop in each eye 3 times per day


Posted by Beth (St. Louis, Mo) on 11/15/2009

Alternative for Rimadyl Needed

My two dogs got into a fight today and one ended up with stitches. He just got home a while ago and is doing okay. They gave me Rimadyl for pain- but considering the chance of horrible side-effects- I'd like to opt for a more natural remedy. I don't want him to be in pain though either- does anyone know anything I can give him for the pain? He's a Border Collie-mix, right around 50 lbs. Thanks for your help!

Replied by Donna
Las Vegas, Nv

Am answering this cause my dog is almost lame in one hip from displaysia, and wew have him on Tramadol. I gave our other Dog the prednizone and rimadyl and she died from her injuries, but was so uncomfortable until she did. The dog, is much better, and there's not the side effects with the Tramodal as with the other nsaid and such. It's worth a try. I found out recently my sister had her collie on tramodal for three years before she died, and she did great. It worth the try anyway, if your having trouble with the other.

Posted by Joanne (Skowhegan, ME/USA) on 04/21/2009

My Pit-Plothound is now 10.5 yrs old. He has arthritis in his neck and front leg. He hollers sometimes when just standing still. I have been giving him 1 Rimadyl (weight 55-100 lbs) for the past 3 yrs only when he is limping or he hollers. He has had no adverse reactions. Because it works for him, he takes it without coercing. Ya! He lets me know (believe it or not). His energy level is good because he reminds me when it is time for our walk. It could be others have issues because of the food they feed their babies. I make mine home-made turkey stew with vegies. I read the labels on the bags and cans and don't purchase dyes, by-products, etc. You can blame a lot of things on the easiest you can get away with, but if you do not care enough to read labels, like you are particular about your own food, their will be consequences that are not good.

Replied by Jodi
Las Vegas, Nevada

Rimadyl is deadly! Please take you pet off this drug immedietly! Please do not allow you Vet to prescribe this to dog almost died because of it. I took him off and he is almost back to his old self. Incredible that there is So much info about this yet you people do not get it.

Posted by Niena (Traverse City, Michigan) on 02/10/2009
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My dog got injured and Rimadyl was prescribed. But by day three of Rimadyl, I was mortified and stopped giving it to him. By day two he had the worst case of the runs so malodorous, so black & sickly smelling - unlike anything I've smelled as a parent, as a hospice worker and after 5 years working in waste treatment plants. He was weak, despondent, confused, constantly thirsty and unwilling to eat anything. By day three I was convinced.

Two days of no Rimadyl and his stool is firming up a bit. He's still thirsty but alert and hobbling around, shaking his tail - and happily eating again.

For inflammation he's munching on fish oil capsules and loving yogurt w/spirulina & ACV. We're recovering. No pet-loving Vet should prescribe Rimadyl - not Ever!

Replied by K
0 out of 5 stars

Our dog also was having problems when walking. Vet prescribed rimadyl...worst thing ever! He had diarrhea for the next few days. It was uncontrollable. Felt so bad for the dog. We stopped it because he was suffering too much. He was back to normal after stopping it.

Posted by Joe (Mentor, Ohio) on 12/30/2008
0 out of 5 stars

I strongly suggest to anyone with a senior pooch to refrain from the use of this drug in any dose, for any arthritis. I gave it to a senior female cocker spaniel and she developed severe heart trouble which led to her demise.

Also, I agree on the rabies yearly vaccinations being unneccessary. I have never had a problem knock on wood, however, I am in doubt as to the need yearly.

Replied by Rebecca
Jacksonville Beack, Fl

I am so against all these poisons for our animals. My Golden/Shepherd mix is almost 12 years... And took her off Demerax (?) and Rimadyl, ... And just give her plain aspirin. She has had only two Rabies shots in her lifetime... I refuse to keep going back.

We had an American PitBull... Beautiful healthy dog until a friend of ours who worked at a Vet's office administered "Advantage Multi" on his back for flea, tick, and worms?? Multi POISONS at one time!! I was against it.... Three hours later he had four grand mall seizures for the first time in his five years... He went right down after that for the next six months, one seizure after another.... This POISON had compromised his nervous system AND his respiratory system!! He got so bad my son had to put him down.... His quality of life was horrible! Well, I wrote the Advantage company and highly complained and accused them of killing our dog and I told everyone I saw, all the Vets around here... And it wasn't long after that.... It was in the news that cats and dogs were dying from this product, and it was taken off the market! I can't find it anywhere. Too many poisons to our children and animals are being given to US... And all at once! I gave some flea medicine back to a Vet when it caused my dog to throw up his entire dinner an hour later. The Vet got perturbed with me because I would not give it to my dog.... I told him IT is POISON to my DOG.... You are killing my dog trying to kill the fleas!! It wasn't Heartguard.... It was a new poison that has to be given with food. So I have had enough... And only give Aspirin, and spray them with alcohol.... They don't have fleas anyway!

Posted by Jean (Johns Island, SC) on 11/16/2008
0 out of 5 stars

My chocolate lab, George - a rescue - was prescribed Rimadyl for early signs of arthritis. No information was given me about adverse side effects, and this was in 1997, several years before the "Client Information Sheet" became available by Pfizer, was given to the vets, who in turn are supposed to give the CIS to their clients. Since this is not mandatory, most vets don't take the time to distribute the CIS.

My George's story may be seen at:

To read about the Class Action Lawsuit against Pfizer - see:

Replied by Kristine
Bayville, Nj

Hello. I do not want to sway anyone, but I wanted to share my experience. I have 2 long haired Chihuahua's who are going to be 17 next month. The one had arthritis so bad at age 8, I thought he was dying. He could barely get up without help. He has been on rimadyl for 9 years now. He takes a 1/4 of a 25 mg tablet per day. He now runs around like a puppy! He is in better shape at almost 17 then at 8. My other chihuahua has been taking it for the past few years, the same dosage. I don't know if it is because my dosage is low (5 pound dogs) but I think the medicine has given my dog a great quality of life. I think you have to research & do what you think is best, but some of the comments like reputable vets would never prescribe are uncalled for. For me, it saved my dogs quality of life & I don't think he would still be alive without it. Like I said, I don't want to sway anyone, but I think you need to research & make your own decisions. Good Luck to you all.

Replied by Susan
Brockway, Pa Usa

I am very cautious to what I give my 13 year old terrier mix. He was in such bad shape, as a 8 month old orphan when he showed up on our doorstep. He needed surgery on his leg and I thought I one point we were going to have to put him down. The vet started him out on 75 mg of rimadyl. I read how it can cause liver damage, so I cut him down to 1/2 tablet and observed him over a period of time. He did fine. So I cut him down to 1/4 tablet with 1/2 tablet Glucosamine Chondroitin. He has flourished and has done really well. I don't understand why vets don't start out an animal on the lowest dose, and move up to higher doses as needed. Especially when it can cause liver or renal damage.


Posted by Gerrie (Plymouth Ma) on 08/02/2016
0 out of 5 stars

On two separate occasions we had depro med shot for our cat and both times she peed excessively while sleeping!! Although this is a miracle drug for allergies we now use steroid pills in low dose.

Posted by Cathy (Ortonville, Michigan) on 02/08/2015


I saw your site while I was doing research on diabetes in animals. If possible I would like to get more information from you. This is why.

I have a 10 year old Huskidoodle, he has always been super healthy. He got an ear infection that was annoying him and home remedies were not working so I decided to bring him to the vet. Besides this ear infection he has not had any other health issues whatsoever and I have had him since he was a puppy, so I brought him to the vet and the recommendation of treatment for his ear infection was an ear cream and a steroid shot. I allowed them to give him the shot and I applied the cream for a week and his ear cleared up and he was back to normal for about a month. Then he started drinking a lot, became extremely tired, not eating like normal and lost 4 pounds and also started having accidents in the house. Which he never has before except in his first 2 weeks of being potty trained. I did not bring him to vet until the second week of this because now I was scared and it was not getting better.

We went to the same vet and he had a urine test and full blood work done. I was told it is diabetes and he was put on insulin 2 times a day. The insulin is Novolin N and for now it is 20 ml twice a day and in 10 days he goes in for a check-up to see if his dosage needs to be adjusted.

I need other peoples opinions about all of this, he was so healthy and happy and active and now he is sick and miserable. Was it or could it have been the steroids shot? It was so quick, from healthy to I thought I was gonna lose my poor boy. Any thoughts would be greatly appreciated.

Sincerly, Cathy

Replied by Theresa
Mpls., Mn

Hey Cathy!

I am sorry to hear about the complications your huskydoodle has experienced.

There is such a thing as steroid/prednisone induced diabetes in dogs; this normally resolves when the steroid wears off [give or take 6 weeks].

However in some dogs that are pre-diabetic, the steroid shot will make the hidden condition obvious; since poodles are a breed that have a predisposed risk of this genetic condition, it makes it that much harder to really know if the shot is to blame, or if this is simply your senior dog's genetic history coming to the surface.

I think the follow up appointment to check the med dosage is a good idea, and I would certainly ask your vet if this might be reversible when the shot is fully worn off. It would also be a good idea to review diet to that if your dog's diabetes cannot be reversed that you do not add to complications by feeding the wrong diet or treats.

I know folks who have had diabetes appear in their 10 or 11 year old seniors in many breeds, and the biggest hurdle was finding the correct insulin dosage; once that was worked out their dogs health and happiness was restored and they lived with great quality of life for many years.

Good luck and please keep us posted!

Posted by Shea (Cloverdale, Ca, Usa) on 05/16/2012
0 out of 5 stars

I took my 12 year old toy poodle and 1 year old cat into the vet yesterday, for what I thought was mange. Turned out to be a really bad skin infection for my poodle and flea allergies for my cat. I made the gut wrenching decision to put my poodle down as his quality of life was so poor. :( They offered to give my cat a steroid shot to help with him scratching and biting. By the time we got him home, his back legs were paralyzed and all he could do was flip and roll around. He looked as though he was having a seizure. I immediately took him back to the vet. When he got there his temp was 106, heart rate close to 350, was blind and still had no use of his back legs. Here I just put down my beloved poodle a hour ago and now I may lose my cat!?

They pumped him with liquids to try and dilute the steroid shot and gave him a sedative to help him relax. It's been almost 24 hours and although he is feeling a little better (is walking and we think has his vision back! ) I WILL NEVER GIVE ANY OF MY ANIMALS A STEROID SHOT! Anybody else ever seen this? My vet said he has given over 500 of these shots in 30 years and had NEVER seen a reaction like this.

Posted by Dp (Louisvill, Ky) on 02/03/2010
0 out of 5 stars

Vet gave Annie a steroid injection last night for an ear drainage problem that antibiotics did not clear up. Annie is a semi-feral and very difficult to treat kitty. She came home last night and ate normally, but this morning is lethargic and won't touch her food. Vet says it may be due to office visit trauma. But I'm very upset and worried.

Posted by Janet (Palm Coast, Florida) on 09/24/2008
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Vet has her on prednisdone 5mg and hydroxyzine 10 mg to relieve itching. Currently she is experiencing shortness of breath or panting. Sometimes at rest she does it. Would these meds cause her problem? Thanks. Oh, doc wants to do skin test on her to find out the source also.

Replied by Adia
Rio Piedras, San Juan, Puerto Rico
0 out of 5 stars


Prednisone for long time use can harm your pets liver. No doubt. I have a 17 1/2 years female dog and after some infections, prednisone, phenobarbiturics etc... she is suffering liver & kidney failure. But after 2 years since last "treatment" and prohibition to give vaccines, antibiotics etc, she is still here. Is true she is very skinny but she eats a lot and dances and barks to whoever comes near the house(she never did this before).she is also almost blind but she goes around the house and to the front patio on her own.She doesn't tolerate vets food.I make her food every two days(she loves fresh made food!) And supplement with omegas, spirulina(protein!!),antioxidants,4Life Transfer Factor Plus, NO tap water, NO sugar, No junk, NO EXCUSES TO GIVE MUNCHIES and NO COMMERCIAL NOTHING.You can search and talk to Pet Alive and NZYMES.They have remedies. I use some on my oldie and on my own. Others are from HEEl lab.(homeopaths) Again,be careful with food. EXTREMELY. There are a lot of things that stimulate the inmunologic system (allergens)and a lot of venom. If you need more info come back to the page. And if you want, leave an e mail for contact.

Replied by Anna
Philadelphia, Pa,usa
0 out of 5 stars

My unspayed dog was given prednisolone -side effect: breast tumors!

Temaril P

Posted by Diane (Rocky River Ohio) on 07/23/2017
0 out of 5 stars

I have a 9 year old English bulldog who has been on apoquel and constant antibiotics for allergies. She went to a new vet who suggested Temaril p. My dog started Wednesday evening with 3 pills followed by 3 pills Thursday morning and evening and Friday morning before I became concerned with her panting. I gave her 1 pill Friday night and called the vet in the morning. I gave her 1 pill Saturday morning and the vet called back in the afternoon with instructions too decrease to 2 pills and so on. I decided to only give 1 pill Saturday night and she was up all night panting. It's Sunday now and I gave her 1/2 pill as to continue reducing the dose. She is not feeling well and I am concerned. What can I do?

Replied by Theresa
Mpls., Mn

Hey Diane,

The drug you are giving your dog contains prednilisone, a form of prednisone which is a steroid. The panting/feeling hot all the time leads to tanking up on water/excessive drinking. Some might consider it a normal side effect as it is very common. If your dog must be on steroids expect continued panting and perhaps offer a fan for her that she can use to cool off when she wants. One concern is to cut down on the dose too quickly; steroids doses should be gradually tapered down to avoid steroid withdrawal symptoms [weakness, joint pain, fatigue]. Due to excessive thirst you will need to make sure you factor in extra potty breaks to avoid accidents in the house. Keep in close contact with your vet if you remain concerned. Have you gotten to the bottom of why your girl is having allergic reactions?


Posted by April (Oak Grove, Mo) on 11/06/2012
0 out of 5 stars

My 10 month old chow chow had reaction to Trifexis. He had it for 3 doses and I finally called Elanco and reported it. They sent a refund to the vet I bought it from. My dog was lathargic and had no appetite for 1-2 days after each dose and after the 3rd month he had strange body movements. They said they would report to ???? doggy FDA or something like that but I don't know if they did.

Unknown Medication

Posted by Abby (Houston, Texas) on 10/11/2009
0 out of 5 stars

I took my dog Blanca (Maltese) on a Monday 2 years ago to the vet because she was coughing. The vet gave me some medication and told me that she thought it has something to do with sinus. Blanca died the following Wednesday. I was and I am still devastated.

I got myself a JRT and now she developed a bladder infection and I can't trust the vet. I am giving her ACV and hope that this will go away.

Replied by Myrna
Ione, Wa

You can also give her cranberry pill for bladder infection. I use a splash of vinegar in my dogs water because it will help them not get bladder or kidney stones.

Replied by Barbara
New Jersey

I have 4 dogs, 3 Dachshunds and 1 Chihuahua, I cook their food and mix my own flea and tick spray, the coughing is a scary thing and should be checked for heart problem if it ever happens again.

I do not trust the dog food companies and would never again use flea and tick drops, they poison our animals. I have had no problem with using my spray made from essential oils, dogs smell good too.