Neuropathy Remedies

Grapeseed Extract
Posted by Al (Alvena, Sk., Canada) on 09/12/2012
4 out of 5 stars

The first natural product/supplement that I tried for peripheral neuropathy (caused by oxaliplatin in chemotherapy) was grapeseed oil and then grapeseed extract in a caplet form with excellent results that allowed me to reduce the amount of hydro morph contin that I was taking by about 40%.

I have told others about it and most that tried the liquid form had stomach upset from it.

I use 50-100 mg three times per day.

Alpha Lipoic Acid
Posted by Al (Alvena, Sk.,canada) on 09/11/2012

I know about flax seed oil. It requires the protein that is in cottage cheese to be mixed with it before consuming to get the maximum benefits. I was at stage 3 with colon cancer when I had the tumour removed and shortly after went on the "Budwig Diet" which is based on flax seed oil(3 tbsp) and cottage cheese(1/2 cup) once daily. I blended them together and added liquid honey and cocoa powder to taste with some extra liquid to make a smoothy for breakfast. This diet is purported to directly attack cancer. Five weeks later all the oversize lymph nodes were back to normal size(that is when I started chemotherapy). I think this indicated that the cancer was gone and thus the overdose of oxaliplatin which damages nerves and the islands in the pancreas especially with a lack of cancer to attack. I have been cancer free for over two years now and only have to overcome the resulting neuropathy to get back to a productive life. Al

Alpha Lipoic Acid
Posted by Al (Alvena, Sk., Canada) on 09/11/2012

I was trying to find the Gotu Kola herb at the same time as I found the ALA but it seems to be unavailable here (in Saskatoon, Saskatchewan). I had to order acetyl-l-Carnitine and benfotiamine as no one had them in stock but could not order the Gotu Kola. Al

Alpha Lipoic Acid
Posted by Timh (Louisville, Ky, Usa) on 09/04/2012 2080 posts

Al, Zinc is very important for healing to occur throughout the body and also boost immunity. Another very important nutrient is the Omega 3 Fatty Acids like Fish and Krill Oil. Flax Seed Oil is converted into the EFA's that the body needs in order to reduce inflammation and promote healing. A native crop in Canada, you should find Flax Oil readily and at a good price in your grocer.

Hope this helps.

Alpha Lipoic Acid
Posted by Bill (San Fernando, Philippines) on 09/03/2012

Hi Al... I think it would benefit your condition if you also took the whole spectrum of B vitamins (either as B50 or B100 complex or as De-bittered Brewer's Yeast forms) which contain Choline, B3, B6, Folate and many other nutrients which would benefit the CNS system. Higher dose B12 is also beneficial to many body processes including the nervous system. For more on the benefits of B12 read David Brownstein's book -- Vitamin B12 for Health. Adding the Gotu Kola herb and higher dose Vitamin C to your regimen would also help to accelerate nerve repair. Adding higher dose niacin(not niacinamide) would also greatly benefit you blood transport system and make it more efficient. Niacin actually changes and thins out the blood safely and the flushing effect of niacin is evdence that the capillaries and peripheral blood vessels are opening up for better delivery of the nutrients you are taking to the body peripherals -- ie to the hands and feet regions. Take 500 mgs niacin twice a day after meals dissolved in half a glass of water for best absorption into the body.

Alpha Lipoic Acid
Posted by Al (Alvena, Saskatchewan, Canada) on 09/03/2012
4 out of 5 stars

I developed peripheral neuropathy from an overdose of Oxalyplatin in chemotherapy for stage 3 colon cancer in February of 2010. It affected my upper palate, hands and legs up to my mid thigh. I have been on Gabapentin, 3600 mg/day, for an extended period of time and then found out it was increasing my blood sugar by 15.0 with a single 300 mg dose so was switched to Lyrica instead. I have also been on narcotic pain killers along with the others and at times nothing would touch the pain or numbness and when nerve testing was done the doctors could not believe that I could still walk as there was zero sensory and zero motor nerve conduction. I had to look where I was putting my feet as I could not feel where I was putting them. I have been very slowly and steadily healing in spite of being put into a diabetic condition by the Gabapentin.

I read about alpha Lipoic acid in an article about fat loss/muscle building with a relationship to insulin sensitivity and it listed five ingredients of which ALA was one. When I looked at ALA in the search engine and read that it would cure neuropathy and that it is used to reduce the side effects of Oxaliplatin in chemotherapy I picked some up and started using it on 1 September 2012. I immediately noticed an improvement in my feet( the only currently affected area). It was so dramatic of a change that I discontinued all other medications to see what it did by itself. I have spent a couple of sleepless nights due to pain and have started using my other medications again today. Other than Lyrica and Hydromorph contin I take grape seed extract, fenugreek, St. John's Wort, milk thistle, glucosamine and condroitin sulfate with MSM, vitamin D, B12, curcumin, Motrin, and Apo-Temazepam for a sleeping pill. After less than 4 hours since resuming my other medications with ALA my feet are about 75% better than they were three days ago.

Is there anything else that I should be taking to speed the healing/reduce the pain and numbness? Please reply directly to gustafsonal(at) Thank you. Al

Vitamin B-1 (Benfotiamine)
Posted by Maya (Silver Spring, Maryland, Usa) on 08/10/2012

After having suffered several acute lower back pain episodes and many visits to the doctor that helped little except the little releif from the strong pain killers prescribed. One night, during a really bad excruciating episode and out of desperation I took a good amount of castor oil and rubbed it on my back. Covered the area with a clean towel and lay on my stomach. The whole area felt immediately very warm and I experienced almost instant relief. It was a miracle! I was almost pain free in the morning. Even went on a 2 hour car trip to the country side and by night I was curling up by the fireplace as if nothing ever hurt. Prior to this, each episode would last for about a week. A week postrated in bed and suffering such horrific pain. Since then, whenever I get the feeling a pain attack is coming, I rub the blessed oil. I always, always carry some with me at all times. Hope this helps you. It doesn't hurt to give it a try. I suggest you read the Edgar Cayce cures using this miracle oil. Blessings!

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Charles555nc (Winston Salem, Nc, Usa) on 08/06/2012

Alpha lipoic acid is a great supplement. However there should be precautions. Only take a max of 100mg alpha lipoic acid every 4 hours, or it will mobilize too much mercury for you to handle.

Alpha Lipoic acid also burns through methylation agents and Zinc. Methyl agents are methyl b12, methyl folate, other b vitamins... so you should supplement with those, periodically, at least 3 hours before and 3 hours after your next dose of ALA.

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Laura (Erie, Co) on 07/29/2012

For 2 years, I was dealing with the pain, shooting sensations, fatigue, electronic vibrations, etc. When my third neurologist said peripheral neuropathy, I found this site, and immediatly began treatment. Because 35% of people with peripheral neuropathy are gluten intolerant, I decided to give this a shot, since diabetes has been ruled out. I have also gone dairy-free, as I've always been a little sensitive to dairy.

After 3 weeks, I already feel so much better, I have stopped taking gabapentin for the pain! There is still a little pain, but the shooting stabbing sensations are gone, and the feeling of restless leg syndrome is gone too.

Here is my daily regimine, specifically:

  • 6:00 am 1000 mg acetyl-L-carnitine
  • 6:30 am breakfast (gluten free, dairy free), 100 mg R-lipoic acid, vit D supplement, fish oil supplement.
  • 10:00 am 1000 acetyl-L-carnitine, empty stomach
  • 12:00 pm 1 fish oil supplement, lunch (gluten free, dairy free)
  • 2:00 pm 1000 acetyl-L-carnitine
  • 5:00 pm dinner (gluten free, dairy free), 1 fish oil supplement, 1 apple cider vinegar
  • 9:30 pm 200 mg R-lipoic acid, 1 B complex supplement.

This is a lot, and I wouldn't do this for more than a few months, but it is amazing how much better I feel in just a few weeks. I will follow up in January 2013, with the final results. I hope with positive news that a complete recovery has been made.

Vitamin B-1 (Benfotiamine)
Posted by Bill (San Fernando, Philippines) on 07/25/2012

Hi Hertsman... You could do no better than to research everything written on ALA by Dr Burt Berkson. He has been researching ALA since the late 1970s and is now a world authority on the use of Alpha Lipoic Acid.

Dr Berkson also makes mention of the type of ALA that he prefers to use -- and that is the RS form of ALA and not the R form. His reasons for this are simply that to manufacture the R-ALA form entails many more chemical processes and steps than it takes to make the RS-ALA form and therefore the R-ALA form will contain, for instance, more trace hexane as chemical residues which are not good for the liver. The manufactured R-ALA form is also much less stable than the RS-form. The R-ALA form is also about 10 times more expensive than the RS-form.

Dr Berkson also advises that the best and purest forms of RS-ALA are made in Europe and not in America or China -- so a good European brand of RS-ALA is what you should use.

Dr Berkson is well-known for using ALA as an anti-oxidant adjunct in his therapies to help cure cirrhosis, hepatitis and cancers. His record as an honest researcher and doctor speaks for itself.

Vitamin B-1 (Benfotiamine)
Posted by Steve (Las Vegas, Nevada) on 07/24/2012

EFT works very well many types of back pain. Here are the points you tap as you focus on the pain:

Vitamin B-1 (Benfotiamine)
Posted by Hertsman (Feltham, Middlesex) on 07/24/2012

So many different suggestions on this thread, difficult to know what to try. So many folk talking about feet but can't find any mention of lower back pain neuropathy? The pain is awful, horrible sore pain that won't go away. I've read that r-lipoic acid is better than the standard lipoic acid. Can anyone give advice for nerve pain in lower back. Any help greatly appreciated. Thanks

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Dana (Ashland, Or) on 05/30/2012

Connie from Slc, Utah, thank you for your comments. I have PN, and have adjusted my diet (gluten free, balanced blood sugar) and have added in many supplements recommended on this site. Do you have dosage recommendations on the ones you state can irritate at high dosage?

I have a problem with ALA. Perhaps because it is a chelator, I feel incredibly toxic any time I take it, even very low dose. I am not otherwise sensitive to sulphur as in onions or garlic. How important is ALA to any protocol of supplements? Do you or anyone here have an opinon on that?

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Zanytranscriber (Port Townsend, Wa, Usa) on 05/27/2012

My husband is taking 250 mg of the alpha lipoic acid once a day and the same for the acetyl L-carnitine 500 mg, once a day. If he is having more "sparkles", he will take another of the ALA 250 mg.

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Zanytranscriber (Port Townsend, Wa, Usa) on 05/25/2012
5 out of 5 stars

I found this website when looking for info about neuropathy. My husband has had two back surgeries and has suffered with neuropathy ever since, especially his right leg. Most of the time, it feels like it is waking up from being asleep with things that feel like sparkles ALL THE TIME, but sometimes he gets something like electrical shocks that zip down his leg. We got alpha lipoic acid 100 mg and acetyl L-carnitine 500 mg at a local store. He started first with just the ALA one tablet and felt relief the second day. After a few days with just the ALA, we added the acetyl L-carnitine. He is able to sleep at night, and even if he has been really active and his leg is doing really badly, it doesn't take as long for the shocks to go away. He has been able to stop taking Neurontin, Methocarbamol, Xanax, etc and is much more active. We tell everyone about this combination, even our chiropractor and MD. We also tell them about the website. Thanks so much.

Alpha Lipoic Acid
Posted by Normared (Knoxville, East Tennessee, Us) on 05/03/2012
5 out of 5 stars

After a bad two-week long spell of sharp, needle-like pain in my feet I looked at this site for advice. At my next doctors appointment a few days later, I checked with him for his opinion, and based on that added ALA to my treatment (which was metanx pills he gave me last year). Within 24 hours of taking one 600 mg tablet of ALA the pains were down by at least 50% intensity, and now a week later they are almost completely gone. A few days ago, I also added a B complex, and plan on adding a B12 lozenge too.

My doctor - a foot doctor who specializes in neuropathy - had no problem with these 'additions', in fact he is the one who suggested B12 in a lozenge form, not a tablet. I'm now a strong believer in taking ALA B vitamins for those pains in my feet!

BTW: Bought my 600mg ALA tabs at GNC - they've got an amazing vanilla flavor and are a pleasure to take! I take 3 per day and a Bcomplex once a day.

Alpha Lipoic Acid
Posted by Sandy (Detroit, Mi) on 04/30/2012


Have you looked into taking b-12 also? Many are b-12 deficient and the symptoms are linked to this. B-12 is best taken in methyl form (sublingual for over the counter) and/or shot or nasal prescription. Many reasons why this deficiency is very common.

Alpha Lipoic Acid
Posted by David (Westford, Ma) on 04/29/2012
5 out of 5 stars

I was diagnosed with peripheral neuropathy in November, 2011. The excrutiating burning on the bottoms of my feet had gotten progressively worse and I really thought my days were numbered. The last thing I would ever want to do would be to go on disability but it seemed like that was where I was headed. I have done everything to help myself. Mind/body 8 week course to learn to live with chronic pain, accupuncture, diet, meditation, yoga and more. Three days after I started ALA I thought my pain had started to reduce.

Now 6 weeks later except for minor discomfort now and then I don't think about my feet 24/7 anymore. I actually drove myself to the Museum of Fine Arts and walked around last week for a couple of hours forgetting that a few weeks prior I never could have done that. I feel blessed to have found ALA if this is why I have gotten better. I have also stopped all statins as I tried just about every one of them. I also discontinued amlodipine as the swelling it causes of my feet I was sure was aggravating my pain. I now take 900mg. Per day and wonder if that is too much? I have read many research articles on ALA and they seem to agree that IV ALA does help neuropathy. There don't seem to be any conclusive studies on oral ALA. I am looking to try and find whether ALA can actually cure Neuropathy or if you need to keep taking it?

Posted by Janet (Fernvale, Queensland, Australia) on 04/28/2012
5 out of 5 stars

I also swear by Turmeric but my understanding is it needs to be heated and taken in conjunction with black pepper for activation. If I have fresh Turmeric I simmer it for approx 10 minutes but if it is powdered making a tea with boiling water is another way to go, I add ginger, black pepper and agave to sweeten and it is a very pleasant drink. I have this drink daily and the pain relief properties are amazing.

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Connie (Slc, Utah, Usa) on 04/14/2012

Hi Mark; This doesn't look easy, but I'll put forth some guesses. Zinc may be needed. It is often times low in people who have become ill with cancer and a large variety of infections. Zinc is active throughout the body, including the nerves. The symptoms of zinc deficiency usually include problems with taste and smell, gastrological disturbance, gonadal disturbance, and growth problems, but there can be many more symptoms. Some types that are easier to find are; zinc gluconate and opti-zinc; I have found these to be effective. Also, a food derived zinc may be gentler on the stomach if sub-divided. There's a zinc-l-carnosine type that may also be easier on the stomach. If taken for long term, a small amount of copper may be needed. ( There are cases of neuropathy that were caused by zinc toxicity that then caused a copper deficiency. These cases were the result of extreme amounts of zinc used, however... in the form of denture adhesives.)

Also, some supplements can worsen neuropathy if taken in too high doses for an individual. B1, B6, ALA, Acetyl-L-Carnitine, etc, may cause irritation.

I found B12 to be most effective for my neuropathy, but it took many months to heal... About a year. But I've also found Zinc to be enormously beneficial for nerve healing. It may take a month or so to see results.

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Janet (Kendal, U.k.) on 04/14/2012

My other half also suffered with Neuropathy caused by blood sugar. He found most effective relief came from MSM and Lecithin. If you research both these things it's understable why. He's recently also gone onto Amino Acids. Following someone elses recommendation. 99% of the time he is now pain free. If it flares then he goes straight back onto the above. We just wonder if he should take it all the time? He can go long spells with no problems. A friend of mine also tried the MSM after cancer treatments and got instant relief. I do hope this helps you. Good Luck and a speedy recovery.:)

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Mark (Mondovi, Wi, Usa) on 04/14/2012
4 out of 5 stars

I had colon cancer surgery June 13, 2011. Then had 9 rounds of chemo starting in August and ending on Nov. 30, 2011. I did not have much trouble with neuropathy during chemo but a month later it started in my feet and then a couple weeks after that in my hands.

I also could not urinate and was told I wouldn't be able to. So I sought out supplements, accupunture, and chiropractic. I can pee now but the neuropathy is still there.

These are the supplements I'm taking:

  1. Calcium Magnesium - 1000 mg C, 400 mg C - Take 2 twice a day.
  2. Taurine - 500 mg - 1 a day.
  3. Krill Oil (fish oil) - 1000 mg - 2 a day.
  4. B6 - 100 mg - 1 a day
  5. B12 - chewable - 1000 mg - 2 a day
  6. Vitamin D - 5000 IU - 1 a day
  7. L-Arginine - 500 mg - 2 a day
  8. Flomax (prescription for urinating) - . 4 mg - 1 a day
  9. Acetyl L-Carnitine - 500 mg - Take 2 twice a day
  10. Alpha-Lipoic Acid - 200 mg - 2 a day.
  11. Methaxyflavone (Vitamin C) - 500 mg - 2 twice a day
    Any suggestions or ideas on how I can get rid of this neuropathy.

Thanks tons, Mark Nelson - mark(at)

Vitamin B-1 (Benfotiamine)
Posted by Timh (Louisville, Ky, Usa) on 03/25/2012 2080 posts

Gatordennis, experiment w/ different medicinal oils like Flax, Borage, Black Currant, Evening Primrose because they influence the body in different ways. Also try an homeopathic nerve tonic. The natural alternative to gabapentin is the amino acid GABA (Gamma Amino Butyric Acid) is very benificial for nerves. Since many cases of PN are caused by some type of toxicity, I would definitely try some detox methods like Oil Pulling, Detox Foot Pads for starters.

Vitamin B-1 (Benfotiamine)
Posted by Steve (Las Vegas, Nevada) on 03/24/2012

You may want to consider googling energy healers. There are many that may be able to reduce your pain significantly.

Vitamin B-1 (Benfotiamine)
Posted by Gatordennis (Bradenton, Fl) on 03/24/2012

I just finished reading the thread on "Remedies for Severe Neuropathy" where I noted the many cure/relief suggestions. My pain started in 1 foot 13 years ago before taking statins, moved to both feet, to both lower legs, to both hands, both forearms, both ears, across my face through my cheeks over the last 13 years. It is like my feet are freezing to death while they are setting in a campfire.

I asked doctors if it could come from fire ant bites, walking barefoot on new Berber (contains (formaldehyde), insecticides/herbicides, & every thing else I could think about that may had changed just before the pain started (none of them were accepted as a reason). I often do not feel other pain from cuts, insect bites & etc.

I have been through 3 neurologists & 2 nerve tests - no help. The prescribed meds (each one taken 6 weeks) either kept me awake for days, slept for days while getting no relief from the agonizing pain. I do not use caffeine, have been on meat/cheese/leafy vegetable diet for 2 years (no gluten). I have tried MANY salves, even mixed in cayenne pepper (some for race horses & other old time remedies). I take 5000 mg of daily D3 for 2 years now (started with 50, 000 mg of D-2). I take multi-vitamin, fish oil, sublingualB-12, tried the Co-Q 10 for years, etc etc.

Nothing has worked or given relief. My 120 mg of daily Oxycodone (for neuropathy & 3 year back pain) only make life bearable. I relate with all of you for your suffering. I will give Alpha Lipoic Acid & Lecithin a try. I am at my wits ends & getting desperate for anything to cover over the PAIN.

Posted by Jill (Clayton, Ca) on 03/11/2012
5 out of 5 stars

I have been suffering from peripherral neuropathy for over 2. 5 years now. Being tired of not finding relief at night, I came up with a solution that works for me. In my garden, I grow Bulbine (very prolific and similar to aloe vera). Since my feet were burning, I thought it might help putting it on my feet. The burning stopped until the gel dried. So, I place several stems of the bulbine between sulifane wrap and roll a rolling pin over until all the gel is squeezed out. Then I wrap my feet before going to bed. In the middle of the night, I have to take the wrap off, but the burning and tingling is minimized greatly for the entire night.

B12 and Metacobalin
Posted by Maria (Gippsland, Australia ) on 02/13/2012

Hi Ms (from Honolulu), If it feels like that they might cramp if you move them any further then I would suggest magnesium. Works for me if my toes feel like or do cramp. Even if it is not cramp it would be worth trying some mag.

B12 and Metacobalin
Posted by Ms (Honolulu, Hawaii) on 02/13/2012
5 out of 5 stars

I also took the same Bs as Shrikant (the fat soluble B 12 & Metacobalin) and my neuropathy in both feet that I had for a few years got better THE NEXT 24 hours I could tell - a difference for the better. I am now still on the fat soluble Bs and it has been 1 1/2 years now. The tingling, the extreme sensitivity, the sudden jerking jolts of what felt like electric shocks within my feet are all gone.

Only thing is lately, I have noticed a tightness appearing and I cannot bend back my toes towards me comfortably. Don't know why...

Posted by K (San Antonio, Texas) on 02/10/2012

I belive my neuropathy is caused by a course of Leqavuin 2 years ago. It started with a numb big toe and spread out. I've taken b-12 patches, Alpha Lipoic, Lecithin, MSM, acupuncture, Bach remedies, NAC, but what feels like a cure:

This week

5 pieces of Turmeric juiced into my morning carrot juice, along with 2 packets of Liposomal glutathione.

I actually credit the Turmeric more than the gluathione, but the two in combination are alleviating all my numbness and prickling for the last 7 days.

Acetyl-L Carnitine, Alpha-Lipoic Acid
Posted by Carol (Los Angeles, Ca) on 01/12/2012
5 out of 5 stars

I was suffering from continual extreme muscle tightness in my thighs and neuropathy in the top of my foot shortly after I began taking Lipitor. I discontinued the Lipitor after 3 weeks, but was unable to exercise without the pain becoming increasingly worse. I stopped taking the Lipitor but had no improvement in my symptoms whatsoever, so after 6 weeks I broke down and decided to try this combination based on Bill's experience. I began taking 500 mgs of Acetyl-L-Carnitine 1x a day and 100 mgs of R Lipoic Acid 2x a day. (I am a small person, so I take a minimal dose. ) I felt relief within 2 days. Five months later, I am happy to report that I am at 98% of where I was before taking the statin with only the slightest bit of tightness and neuropathy when I exercise hard.

You should always check with your doctor and investigate as much as possible before taking a supplement with a prescription drug or other supplements. I believe my original problem with Lipitor was caused by inadvertently combining it with Red Yeast Rice.

Vitamin B-1 (Benfotiamine)
Posted by Juliamary (Johannesburg, South Africa) on 12/09/2011

People who have burning feet - do you realise that it can be caused by too much caffeine? Caffeine prevents the absorption of vitamin B, so that even if you are eating well and having vitamin B supplements, that vitamin B is not being absorbed. The reason why some sufferers are not getting any better when they take various remedies may be because they are drinking eight cups of strong tea or coffee a day! Give it up and see the difference it makes.

Alpha Lipoic Acid, B12
Posted by Shrikant (New York) on 11/15/2011
5 out of 5 stars

Hello.... I had feet burning for a long time(2 - 3 years). Earlier to that I found my feet was paining a lot. I am diabetic for the last 30 years. Obviously it should be diabetic neuropathy. Recently I tried Benfontamine (fat soluble Vit B1) 200 mg twice a day alpha lipoic acid 600 mg Methylcobalmin (B12 variety) that aids the process of methylation. I found that the feet burning has been controlled substantially. I used to take alcohol in moderate amount. The day I take alcohol my feet burning erupts and the day I stop it goes away. I think alcohol has something to do with my feet burning and I have now decided to discontinue alcohol altogether! Let us see.


New York

Gluten-Free Diet
Posted by Deb (Wloo, Ia) on 10/27/2011
5 out of 5 stars

My ex had severe neuropathy and many more problems. He decided to go on his diet as he found out that he was a celiac at age 55 but didn't bother to follow the diet. :) He finally tried his gluten free diet at 61 and after just two days he felt much better. Now three years later he is 99% better. Doesn't have acid reflux, brain fog, out of breath, tired, pain in feet and legs.

Alpha Lipoic Acid
Posted by Ale (Cardiff, Uk) on 10/27/2011

Hello Monique,

A friend of mine had a crippling neuropathy in both feet and couldn't even walk. She went to get osteopathic adjustments just once or twice and now the pain is almost completely gone. You might want to find a good osteopath in your area and give it a try. Good luck!

MSM, Lecithin
Posted by Janet (Kendal, U.k) on 10/26/2011
5 out of 5 stars

My partner too suffered with neuropathy, that was till we discovered MSM and Lecithin from his first dose he got almost instant relief. And after only a month or so has never had it back. Hope this helps.

Alpha Lipoic Acid
Posted by Debbie (Melbourne, Australia ) on 10/26/2011

Monique you can try "earthing" for your pain. The most simplest way to do earthing is for you to sit with your feet barefoot on the earth (or grass). You can do some research but I have read it helped someone with neuropathy of the feet.

If it helps you can also back earthing sheets for your bed and even the computer. The best shoes to wear are leather soled shoes because they still earth you to the ground.

Lots of info available on earthing.. May be worth a try... Just sit or outside barefoot and see if it helps. Would love to know how it goes.

Alpha Lipoic Acid
Posted by Bess (Calgary, Alberta, Canada) on 10/26/2011

Hi Monique - You may want to increase your Vitamin B12 (Methylcobalamine - take sublingual tablets) and ensure you take a Vitamin B Complex as well. I've read that Vitamin B12 protects the sheathing surrounding nerve cells and can promote regeneration and growth of nerve cells.

Also, be tested for Vitamin D deficiency ( or Vitamin D Council have lots of info on this). If you do an Internet search for "vitamin D deficiency neuropathy" you'll find lots of information suggesting you get your Vitamin D levels up. Good luck!

Vitamin B-1 (Benfotiamine)
Posted by Monique (Elllington, Ct) on 10/26/2011

Hi there, I have terrible neuropthy in both feet and the pain has become unbearable. I've tried lots of "cures" and keep searching and researching, It is by no means a cure, but I have been going to the YMCA on Mondays for 1/2 foot massages. It doesn't take away the pain, but there is something about a gentle foot massage that feels good to me. My children, 7 and 8 also massage Mom's feet every night before bedtime. My feet are incredibly sensitive to touch, but just knowing someonone is caring about them helps a tiny bit. I tried to get my insurance to cover the foot massage at the YMCA but of course they wouldn't. Any other suggestions anyone has, would be greatly appreciated. Also, I live in Ellington, CT does anyone know of a support group in my area? I was thinking of starting one myself but don't know the first things and really wonder if I should undetake it with how I feel. I don't want to get together and just complain of our pain but would like it to be a positive forum to exchange helpful hints to one another.

Thanks, Monique

Posted by Monique (Elllington, Ct) on 10/26/2011

Kate, you are not alone. I've had terrible Neoropathy in both feet for 4 1/2 years. Its a terrible way to live. I'm trying to research cures and came across this site. I even had a Spinal Cord Stimulator trial implanted but it didn't work for me. Supposedly though, it helps lots of people. I haven't read many people on this site who have tried it. Also, I guess there is a nerve root stimulator too which is similar and works for 2 out of three people. I went to the Lahey Clininc in Burlington, MA for my SCS. It's something you cna look into. I'm at a point I don't know what else to try, has anyone had luck with acupuncture? I tried it years ago with no sucess but I'm going to try again. I have a 7 and 8 year old to raise and can't go on feeling like I do. I have a high tolerance for pain but it's even more than I can take now. Good luck yo you. Let me know if you find anything out.


Alpha Lipoic Acid
Posted by Monique (Elllington, Ct) on 10/26/2011

I have extemely severe neuropathy in both feet which is getting worse. I'm scared. I've tried the alpha lipoic acid and acettyl-l-carntine and everthing else too. Nothing, not even pain meds like oxycodone touch the pain. I have a 7 and 8 year old to raise and the pain has become unbearable. Any suggestions from anyone would be greatly appreciated.

Posted by Kate (Avon, Ct, Usa) on 10/21/2011

Hi John,

I can feel your pain.. Literally. I've been suffering from horrific pain in my feet for almost 3 years now. As of the past few weeks, it's began to spread up my legs and I am experiencing stabbing sensations and cramping as well(grrrrr). I have a long history with Lyme Disease and co-infections so since I test negative for literally everything else the docs can come up with, it seems Lyme is the origin.

I have been on Neurontin for as long as Iv'e had this problem and about 6-7 months ago began a strict regimin of ALA, Benfothiamine (600 a day), Acetyl-Carnatine and more. I seemed to hold for a while but now things are exploding and I have no idea why. I have been taking 25mg B12 injection 3x's a week for about 4 weeks now. To no avail (sigh). About 2 weeks ago I decdied to give up carbohydrates in another desperate attempt to stop this incredible pain.

I hope and pray you find relief asap as so many posting here have. I have learned a lot simply by stumbling on this thread so I thank you for that.

A great sight with a TON of info on supplements, etc for neuropathy is "Neuro-talk. " Find the peripheral neuropathy section.. there is a tremendous amount of information to be had and much like here, a tremendous amount of support.

Be well, Kate

Estrogen Neuropathy
Posted by Sue (Phoenix, Az) on 09/03/2011
5 out of 5 stars

Estrogen can morph into neurotransmitters. So on some level you could say it is a neurotransmitter. As hormone levels drop neuropathy can occur. Neuropathy in women can start within a decade of approaching menopause. There are quite a few studies out on estriol and Parkinsons as well.

If you know a senior lady who suddenly developed some neurological condition who is trying to find some answers, a good question to ask is "Did you recently stop taking estrogen?" I know of several women who developed neuropathy after 30 years of estrogen therapy- just stopping. There are some natural safer ways to increase estrogen, I understand.

What helped me was a very small daily dose of natural thyroid (not the synthetic). I tested fine but my body temp was always around 96.8. Subclinical thyroid conditions do exist and if there is neuropahy it is worth researching as well. I did not know it would do this. I was just tired of wearing a winter coat at work and shivering in the desert.

If iron is low neuropathy can occur. My experience is that the homeopathic Carc Carb 6x or blackstrap molasses (huge section in this site) was real helpful. I used to go to a Dr. In Pa who demand that you take blackstrap molasses every day. If you did not he could tell.

Anyway it is worth doing a search on the following: "Estrogen Neuropathy" "Menopause Neuropathy" "Anemia Neuropathy" "Hypothyroidism Neuropathy" "Estriol Parkinsons" Estrogen Neurotransmitter"

Another thing that can help is searching "Dosha Test" If the body type is Vata neuropathy can occur. There are ways to make corrections to diet and sleeping schedule that can bring relief.

Posted by John (Plymouth, Ma) on 08/28/2011

Kelley, Yes I have tried Alpha Lipoic Acid, but for another issue... It did not agree with me... It made my heart race terribly... Don't know why... That was about 10 years ago.. I have recently found out that by eating raw potatoes you can get your Alpha Lipoic Acid... I don't know what the strength would be though... It is something I will certainly consider...

Thank you very much for your concern and time posting you recommendation... It is greatly appreciated...

This too will pass.......

Bless you

Posted by Kelly (Cambridge, Ma) on 08/26/2011

John - Have you tried Alpha Lipoic Acid capsules? It's worked wonders for me and scores of others.

Posted by John (Plymouth, Ma) on 08/25/2011

Hi Connie, You sure are certainly informed with regard to P.N. And many other things. I cannot thank you enough for your time and support. You are heaven sent. You will indeed get your hit record.

Regarding the magic bullet for P.N. I'm going to give benefotiamine a try, if all else fails. I have researched it throughly. It's a man made form of Vitamin B-1 (Thiamine).

Again, NO ONE was put on Earth to suffer. We all are here to thrive.

Bless you.

Posted by John (Plymouth, Ma) on 08/25/2011

Hello Anna, At what strength did you use magnesium chloride? How often per day?.. Pill or powder?

Thx much...

Posted by John (Plymouth, Ma) on 08/25/2011

Thank you for the information...

God bless....

Posted by Anna (Toogoolawah , Qld Australia) on 08/24/2011

You should use only Magnesium Chloride for oral use, and it should be Food Grade. You can buy it from Food Ingredient companies in NZ and Australia by the kilo. Costs about $33. Checkout Paddy Melon & The Melbourne Food ingredient Depot. They supply all the Vitimins and minerals to the food manufactors in Australia, and they will post it to you. I buy all my stuff there or in a produce store where I is much cheaper than Natural food stores. Magnesium Chloride is a wonderful mineral for lots of ailments taken orally and as a bath/foot soak.

Good luck

Posted by Connie (Slc, Ut) on 08/24/2011
5 out of 5 stars

Hi John P. ; I do hope you're having some improvement by now with the B12. Have your symptoms changed at all? Oftentimes as nerves heal, numbness, tingling, and pain can alternately diminish and return temporarily. Temperature sensitivity can also shift. Although I've tried numerous subtances for neuropathy, the B12 has worked best far and away. But this only means that it worked for my case. (though there are many case studies to support B12's efficacy with neuropathy). Still, the folks here are offering good suggestions as these supplements also have an excellent track record for treating nerve injury. I also welcome suggestions because someone may just pop us the right answer!

I see you are trying transdermal applications. It still surprises me how powerful they are. In fact, I cringe when I recall that I've coated my hands with paints that were loaded with heavy metals. Then I would use nasty solvents to remove them. Now I use gloves. But I do use the solvent, DMSO with some transdermal applications. I've added 4 (20mg) B12 lozenges, crushed with a mortar and pestle, to a 1 oz. Dark glass dropper bottle, mostly filled with DMSO. I shake it vigorously for a few minutes until dissolved. This is an approximate recipe developed by Dr. Gregg. I've used this off and on for several years with good effects. I buy the DMSO and supplies from a chemical shop. The mixture is a bit sticky, and the flavorings make for an unusual scent, but it did help me. I would often use it on my left hand which had become frighteningly stiff and numb. I'm now trying it on the small numb spot on my heel to see if it speeds recovery. Castor oil is also a great medium to use either alone or with added essential oils, some good warming ones could be : Oil of Oregano, Cinnamon Oil, Black Pepper Oil, and Ginger Oil. Cayenne is very warm, but I have only seen it as a powder or extract. There are some ready-made salves, but some are with cooling mints. I do have one that is warm, it is called Badger sore muscle rub. It is mild. Good Wishes.

Posted by Janet (Kendal, U.k) on 08/24/2011

MSM:-(Methylsulphonylmethane. ) It's available in tablet or crystal form, the crystals are said to be quicker absorbed. Health food shops sell it or available online. It, s sold usually to supportjoint comfort and mobility. We googled what are the health benefits of MSM for diabetes, and came up with a great page explaining all about it. Usage , dosage, etc....

Posted by John P. (Plymouth, Ma) on 08/23/2011

Hi Connie, Thanks for the great suggestions.... I currently rub my legs with magnesium oil fro "Ancient Minerals", however I don't know if it has been working as I have been doing it for only 2 weeks... No results... Yet... Rubbing castor oil may be a good idea as it is highly recommended for hep-c in a pack against ones liver for an hour or so per day via Edgar Casey and many other current people... So transdermally it may help significantly... I will try it on just a small part of one leg and see if I get any kind of reaction with my hep-c.... I am so cautious with adding things as I have had bad reactions to many things... I feel this is because of my liver..

Thank you again so very much, John P.

Posted by Connie (Slc, Ut) on 08/20/2011

Hi John P. ; A few days ago, I asked myself ; What has B12 not done for you? My hair is still 40% gray, and I haven't yet written that " hit song". Each day is a bit better, but it's so slow for me. When the neuropathy was at its worst, I began with a litany of supplements to cure it , but I was using so many at the same time , I couldn't discern what was working. I became confused. My studio became an apothecary. When I look back, I realize that there were so many obvious clues for me, but I was distracted with pain and fear, and I had spent my life on denial of my instincts. I've got a way to go with that. What I'm learning from you is that you are going about your healing process logically and methodically. I appreciate this. Although B12 is not the only one thing , Its pretty dang'd powerful. There have been and there are currently tests being done for people with MS and early ALS to at least improve their status. The amounts being used are 50 mgs. Daily by injection. This means that there could be a wide variance in an individual's needs. I've tried a wide variety of amounts, and I'm still somewhere between 2500 - 5000 mcgs. Daily now.

I've " haunted" some forums, and it appears that other people are trying a wide variety of amounts, but, most seem to be settling in the 1000 - 5000 mcg. Range. Some are lower, and some are extrordinarily higher. I have been influenced by this information, so I need to be mindful of it when making suggestions. Another thing I am noticing about B12 is that it is raising my body temperature and I am feeling warmer. ( I've read this and now I'm seeing it. I'm at 98. 2 degrees now). I believe it will help with cold legs eventually. I also believe that massaging legs and feet with oils can be wonderful. (my skin is dry, so I use castor oil). I've used various salves for pain with good effects. Since you have coldness, I would recommend that warming spices be added to your salve, such as Ginger, and Cayenne. Ginger has been recommended to raise body temperature and improve circulation. ( internally and transdermally) Best to You.

Posted by John (Plymouth, Ma) on 08/19/2011

Hi Connie,

ThanKs for the reply... I'm wondering what amount of B-12 are you currently taking? I have gotten up to 10, 000mcgs... I went very slow for obvious reasons... I have only been on this for less than a month... If it took you 6 months, I guess it will not be overnight with me either... I tried taking lecithin and it thinned my blood out (assumption) and I have gotten very cold as of today... I got a commendation to rub coconut oil on my body... Don't know if you've heard of this... I may try it on a small part of my leg for starters and see what happens...

I am extremely grateful for your advice and your quick response...

God bless, John

Posted by Connie (Slc, Ut) on 08/19/2011

Hi John P. ; I truly hoped that you had knocked that neuropathy out of the park right away, but it usually does take time to heal nerve inflammation. It took about 8 mnths. For me , 3 1/2 yrs. Ago. Then, when I stopped taking it daily, and regressed, it took several months to again heal the nerves. Even after restarting B12, I still regressed during the first month. Now in my 6th month, I have a small, shallow numb area on the heal of my left foot, and it is recovering feeling. The area around it is sensitive and tingly. This means that time is necessary. Also, it means that we're going to have to get more technical with your process.

Firstly, I've read that oftentimes with liver trouble, potassium could go low. That can cause some cramping and pain. If you are not taking any potassium sparing meds. , such as some certain diuretics or anti-hypertensives, then consider increasing potassium foods. ( careful with the sweet ones, they can cause pain). Consider getting a copy of blood test and observe electrolytes. ( I find I feel best when K is about 4.5 mEq/L). Fresh vegetable juices are great, carrot, celery, and added greens. Smoothies are also a great option, as are homemade broths with the retained liquid from the veg.

As I see that you have expressed a sensitivity to acids, I agree that reducing them is a good way to alleviate pain. The nerves are exposed, and even beneficial acids can cause pain now. Although citric acid is natural and good, it is added to so many foods as a preservative, that it is easy to get too much. Even ascorbic acid can cause pain. I don't recommend total avoidance, but some reduction. I recommend a food type B-complex. (new chapter). It's expensive, but less is needed. I've found that it doesn't cause pain when taken with meals at 1/2 to 1 tablet. B1 and B6 are good for nerves at lower dosages, ( personal opinion ). Also, the fat soluble vitamins, A and D, can be difficult to metabolize when there is liver trouble, so I recommend getting them from food rather than supplements. Good Wishes.

Vitamin B-1 (Benfotiamine)
Posted by R. (Dallas, Texas) on 08/19/2011

Eugene, Its been 4 months since you started, how is this Benfotiamine working for you? I am interested in trying this out! I have tried everything else and nothing seems to work for very long periods of time! Thanks in advance!

Alpha Lipoic Acid
Posted by Robert Henry (Ten Mile, Tn Usa) on 08/19/2011
5 out of 5 stars

My neuropathy is due to diabities and I take Alpha Liopoic Acid intravenously and by pill. A lady who has hep c was the person who got me on this regime. It helps.

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