I came across Butterbur and Feverfew as recommendations for Migraines and decided to buy both for my husband who has migraines due to multiple Traumatic Brain Injuries (TBI.) Most people who write about treating migraines tend to have had them most of their life, or it's related to their menstrual cycles, so I didn't have high hopes. Previously, the only things that have worked for sure have been Botox (to freeze all the muscles along the skull front and back) or percocet (which pretty much works with everything but it's a pain to try to get that from the doctor's due to drug-seekers.) Otherwise, if he's lucky, at the start of a migraine, he can take 1600 milligrams (that's right, 8 200mg pills) and get it to go away. However, this doesn't always work, and on top of that his doctor warned him that he'd be at risk of renal failure if he happened to be dehydrated when taking such a dose. The doctor was otherwise worthless.
I've been giving him 3-4 Feverfew (380mg per pill) pills a day, and 3-4 Butterbur pills a day as well. It's not til now that I've realized the Butterbur has extra Feverfew thrown in. (ButterBur 75mg and Feverfew 200mg.) So far, it's been three days since he's had a headache or migraine. February 9th and 10th he had a headache (which is fairly unusual--he tends to get migraines every other day--sometimes everyday, sometimes only 2-3 times a week.) It's now the 12th-- so clearly not definitive at all, but I wanted to put this out there since it's promising so far. I plan on giving him these high doses until the two bottles run out (which I bought at the natural food store) and then buying online and bringing down the dose and seeing if a migraine shows up or not.
I've looked into overdosing and it's mainly digestive upset-- he hasn't had any of that.