I just started painting twice a day. I have always had irregular menstrual cycles and cysts and recently started having problems with acne. It has been about 1.5 weeks now and my acne is almost gone. I have had acne problems for the last 6 months and tried everything over the counter and topical you could imagine. I was ready to give up and go to the doctor for meds. Thank God for iodine! It is too early to comment on the female issues, but I am having some positive signs in this area too.