Hi I had sludge in my gallbladder which was causing a lot of discomfort. After taking ACV to manage the pain, the doctor suggested taking Urso, OX Bile to reduce the amount of sludge. Within two months after taking Ursodiol and Taurine twice a day, I did an ultrasound and the sludge was gone. I am also managing my diet by avoiding fats, oils, dairy, and other triggers. I do not need to continue the Urso and Taurine anymore but may need to take it the sludge comes back. I am so thankful for this site and for everyone's generosity in sharing their tips for managing their ailments.