Science Daily article:
From Kansas State University
Treat the fungus among us with nontoxic medicinal compound
"Taking the medicine could potentially help patients control the invasive growth of the fungus and also help bring their sugar levels down." – Govindsamy Vediyappan, assistant professor of biology Govindsamy Vediyappan, assistant professor of biology, noticed that diabetic people in developing countries use a medicinal herb called Gymnema slyvestre to help control sugar levels. He decided to study the microbiological use of Gymnema slyvestre -- a tropical vine plant found in India, China and Australia -- to see if it could treat a common human fungal pathogen called Candida albicans.
The investigation was successful on two levels: Vediyappan's research team found the medicinal compound is both nontoxic and blocks the virulence properties of the fungus so that it is more treatable.
The results are important for human health, biomedical applications and potential drug development. "We have shown that this compound is safe to use because it doesn't hurt our body cells, yet it blocks the virulence of this fungus under in vitro conditions, " Vediyappan said. "Taking the medicine could potentially help patients control the invasive growth of the fungus and also help bring their sugar levels down."
Candida albicans is one of the major fungal pathogens in humans because it lives in oral and intestinal areas as a normal flora, Vediyappan said. But the fungus can overgrow and can cause oral, intestinal and genital infections.
The mortality rates for those with candidemia and invasive candidiasis has been reported to be quite high, and it is a concern among cancer patients -- especially patients with neck or oral cancer -- HIV patients, organ transplant patients and other people with compromised immune systems.
The fungus can grow in two forms: a treatable yeast and a difficult-to-treat hyphal form. Once the fungus transforms from a yeast to a hyphal growth it becomes difficult to treat because the hyphal growth has long filament-like structures that can spread into various organs.
Vediyappan's study aimed to block the hyphal growth form. "Once it gets into the tissue, it spreads like roots and is difficult to contain by our immune system, " Vediyappan said. If the fungus remains in yeast form, it is easy to manage and does not invade tissues. Vediyappan's research team purified gymnemic acid compounds that prevented the transition stage from occurring and stopped the fungus spread. The gymnemic acids come from the leaves of Gymnema sylvestre, a traditional medicinal plant. The research appears in the peer-reviewed journal PLOS ONE in an article titled "Gymnemic acids inhibit hyphal growth and virulence in Candida albicans." Gymnema extract is commonly used to treat diabetes and other ailments because it is a cost-effective treatment, Vediyappan said.
Often, people drink the extract to control their sugar levels or to lose weight. Although Vediyappan's research team is not the first to discover gymnemic acid compounds, the team is the first to discover that the compounds block the fungal transition.
The researchers found that the compounds work quickly, too, which was an important characteristic. The treatable fungal yeast can transition to a hyphal growth within 30 minutes of an infection. When the hyphal transition has occurred, it will grow into branched filaments.
The gymnemic acid compounds are nontoxic, which is especially important for cancer patients and other immunocompromised patients. The gymnemic acids can stop the unwanted invasive infection while preserving important healthy cells. The Candida albicans fungus also makes a biofilm, which is a fungal cell collection that can be difficult to treat. The researchers found that the gymnemic acid compounds converted the biofilm back to treatable yeast cells. "This compound prevents the biofilm formation because hyphae are the major builders of biofilms and biofilms are resistant to antifungals, " Vediyappan said. "Yeast cells by themselves cannot make biofilms and are sensitive to antifungal treatments."
Another interesting aspect: The gymnemic acid compounds also stopped the growth of Aspergillus, another fungal pathogen that can affect heart transplant patients and leukemia patients. Vediyappan plans future studies to research mode of action, potential drug development, diabetes applications and other ways to improve treatment for Candida albicans and other fungal pathogens.
Fungal infection on the scalp:
I have had extremely itchy scalp since being diagnosed with seborrheic dermatitis two years ago. It began with taking amoxicillan. The dermatologist prescribed an elocon steroid lotion which I used but it actually didn't help and the side effects worried me. This summer I had the most unbearable itch that would spread to my face. I finally found a cure when I read that applying honey on the scalp will alleviate the fungal infection. After using that method for the three months, the itch has gone and I now just apply coconut oil with vinegar. I urge anyone to try honey as the results are remarkable.
Mix two tablespoons of honey with one spoon of water.
Hello, I used iodine on a bad skin fungus infection I had on my right arm. I tried alot of natural remedies...Aloe Vera, Coconut oil, Castor oil, ACV, Tea Tree oil but all seem not to be working as when applied, the virus would just explode and spread further or would scale back in size for a minute but then grow. I tried different things for around 3 months. I then read online - a different website - about iodine and a testimonial, purchased some from Amazon and applied it. It hurt when I applied it, subsided in pain for a while but fluctuated in intensity for a while then ceased. I noticed the infection looked dried and did not explode.
In 3 days I was cured and the infection was healing over. I then continued to apply Castor oil to heal the mark the infection left.
Definitely use iodine if possible to kill a fungus skin infection - avoid the doctor visit and co-payment. Not sure how to use this for a yeast vaginal infection as iodine stains and can be sensitive to a open sore like Tea Tree oil. Great Stuff, I recommend.
A few months ago I scratched my inside vaginal opening with period pad which I was wearing. Next 2 days I saw orangish red blood spots but I ignored it that it will be healed by itself. But as the time passed I found out that particular area getting bumpy, itchy and inflammed. I went to the GP. Fungal infection was diagnosed & hence I was given Diflucan. Ater the completion I was again tested and slight bacterial infection was diagnosed but the doc said it's alright. A month later I had to take metronidazole and I started getting the same fungal symptoms hence I went to a doctor and bacterial infection was diagnosed. I inserted canesten (broad-spectrum antimycotic with fungal action and trichomonacide) 1 vaginal suppository 2 times for 3 days. When my periods date approached (same day when last period started in the previous month) the pad was stained then no periods again for full day. Next day it happened again. Today is 3rd day. I am having period pain. But the periods are still stuck.
Please help with your good suggestion what is it and what should I do in the longer run as well? Thanks.
For the past three years I have been suffering from an unknown infection in the corner of my eye. It took a long time to finally figure out it was (as far as I can tell) a fungal infection. I used ACV on it and IT SPREAD EVERYWHERE. I had to be careful because it is very close to my eyeball, but finally found lavender oil and eucalyptus oil. I dilute and wash my face with one drop eucalyptus, 2 drops lavender oil to 1 teaspoon of water a few times a day. So far so good! I will continue until the bottles are empty, probably a few months or so.
Fungal Skin Infection:
I have had a horrible rash in the fold of my skin in my belly for months now.Intially I had it under my breasts too. I went to a dermatologist, who gave me diflucan and ketoconazole. After several months it did go away. Then it came back, but just on my belly fat and around my perineal area. I don't have insurance so I tried many "natural" cures. But nothing is working. My skin is raw, if there is any help anybody can give, I would greatly appreciate it.
I am new here. Neat stuff!! I have had a serious fungal over growth and been helped with Riff techology but still have some resistant yeast or fungus in sinuses and lungs. I have leg muscle and hip, knee and ankle joint pains. Walking is sometimes very painful. I want to get rid of the rest of this. I started taking baking soda in water after getting some info off of YouTube. I was doing it before meals which I am now corrected on. I got a headache with this and I had hoped was die off but probably not. I will follow Ted's formula with lemon or lime juice with water and bs. I want to add borax. Do I add this to the same mix and take after eating?
Also I am getting some relief from transdermal magnesium but would like to take epsom salts and baking soda baths but I have city water which is chlorinated. I saw on one of Ted's replys were he said he added sodium trisulphate to de-chlorinate his drinking water. Does anyone know how much I might need for a bath and what kind of proceedure to use if I find out, so I can soak for an hour with out chlorinating myself?
Also I have had my gallbladder removed and what to know of any precautions I should take with any of the formulas mentioned which I plan to use.
Thanks to anyone who might be able to help me figure this out.
Richardson, Tx, Usa
I contracted a fungal skin infection nearly a year ago, which started as a couple of tiny red areas on my stomach. It quickly spread to become big red patches all over my torso, my back and everywhere that "sweated" like under my breasts and in the skin folds you get when you sit. I was quite horrified as I've never had any skin infections, not even so much as eczema. I tried all sorts of homeopathic remedies and had no luck, I was actually getting really worried as it was still spreading "south" and I really didn't want it in my groin area!
I went to my doctor and she dismissively said "Oh that's really common, I can prescribe you a cream for it but they commonly don't have any effect. In most cases the body will eliminate the infection within 18 months. " I'd already been battling it for 8 months and it was made worse EVERY time I exercised no matter how good I was at washing, staying dry and airing out. It had spread to one armpit and the insane itching it caused all day was almost too much to bear, and nothing I applied topically helped for very long.
I was really disheartened, but I did read on here that Oregano oil was worth a try for some people. I had AMAZING success with it ? I applied it undiluted with a cotton pad, and it was great on the torso area where there was no raw skin. It does burn though, boy does it burn. On sensitive areas like the underarm it honestly will take your breath away like an acid burn, for 20 minutes or so, so I found mixing a few drops with jojoba oil works very well as you can apply this more regularly. It also has the added benefit of eliminating underarm odour! I didn't actually need deodorant when I used this treatment. As long as you don't mind smelling like Bolognese sauce! It took only 3 or 4 days of applying this once or twice, whenever I could practically do it, to get rid of my infection and it hasn't returned. It's completely gone. I was gobsmacked. I am so relieved in every sense of the word! Best remedy for fungus ever in my humble opinion.
On June 20, 2012 I started searching on the internet for an alternative treatment for a recurring fungal infection which has appeared on my right hand 3 years in a row. For 3 solid years, this fungus has appeared, lock clockwork, in early summer. I have seen a dermatologist, been prescribed multiple creams and even had a very expensive biopsy done in 2011. Nothing seems to work but time. Meanwhile, I was in misery trying to reapply creams & lotions after every hand washing and wrap my hand up at night so the ointments would stay put long enough to work. It was futile. So last week after reading several posts here about the efficacy of Absorbine Jr. On ring worm, I thought, "why not"? Thank goodness that others took the time to post their results! After a week of use (4-8) times/ day, the fungus is nearly gone. I am going to continue use of Absorbine Jr. For at least another week because I know it will come back due to the nature of fungal infections. Normally it would have taken 3 months and lots of battling to get rid of this stuff. Today, I am itch free and 90% cured! Perhaps it is the fact that Absorbine Jr. is a liquid and can dry on your skin instead of coming off constantly requiring re-application. Or, perhaps it is the ingedients that really work or some combination thereof. Frankly, it doesn't matter. It works.
P. S... When you go to purchase this stuff at your local drugstore, be mindful that it is currently marketed as an arthritis and sore muscle treatment. You will have to read the side of the box to see that it can also treat athlete's foot (fungus) to be assured you're buying the right thing.
Potassium Sorbate for Cancer/Fungal Infections
There is a brand of ice tea that contains potassium sorbate that I used to drink when I felt unwell because it made me feel better. It contains potassium sorbate, an additive used to prevent mold.
My son works on the grounds of his college. Got pricked by a rosebush on left ring finger and it swelled and stiffened to the point of not being able to use it last night. Is better today but in reading, he believes he may have a slight case of sporotrichosis, which is a fungal disease. Since there is no real opening, wondering what would be good to treat internally to make sure to keep the fungus at bay. Any ideas would be helpful.
Middletown, Pa, Us
I hope this doesn't sound mad but the other day I stubbed my finger and straight away stuck it in my mouth but weirdly it tasted of mold. Since then I've noticed it again but it seems to be gone now. I'm madly curious as to why your finger would taste of mold. I dont think I have candida but maybe I do!! . I would love to know-am I alone or does this suggest that I have a fungus or mold problem. Any feedback back would be great. Thanks.
The Beach, Canada
Hello Ted: I have written you a mail, but I got no reply which I understand, but please tell me if my treatment plan sounds OK to you, or have I misunderstood anything?
I have gathered information however, that I think is suitable for my treatment (hair loss and fungus (after a trip to India, I slept in a room with mold everywhere for one month):
Iron, even though its low, I should stay away from it because it feeds fungus (actually I get small rash on my hands everytime I ingest iron)
Low copper--> I will take sodium copper chlorophyllin 200-300 mg a day! (everyday for 2-3 weeks) and 2mg normal copper 4 days a week
Zinc: I have sufficient zinc in my hair analysis, but I will take 10mg a day nontheness (3 days a week)
Manganese- I have taken manganese for some time now, off and on, but I will take 15 mg 4 days a day
The B3(bedtime), MSM, BORAX, baking soda with lemon taken internally and b3, msm, borax applied topically also. 1/2 teaspoon of each with 1 tablespoon of water applied throughout the scalp. Overnight. (borax 1/8 in 1 liter of drinking water, and adding a large pinch of borax to the mix of topical application overnight. MSM taken internally around 1000 mg x 4 or x 5 to help kill the fungus)
Vitamin C sodium ascorbate 1000 mg everyday for 2-3 weeks, then reduce it to 500 mg
Molybdenum- Cannot find sodium molydate, and I have very low levels of that, but I found ammonium molybdate which I will take 1, 2 mg every day for 2-3 weeks, one day of per week)
Magnesium citrate 500-600 mg 5 days a week, I have very low levels of that as well!
I will try to find cooked liver found in chickens and pork, to get some iron.
Meanwhile, stay away from everything unhealthy! After these weeks, 2-3 weeks, I will only take some molybdenum (400mcg), some manganese (7, 5 mg), magnesium (300 mg), and borax 1 or 2 times a week.
Additionaly I will take some fulvic acid, biotin, PABA and amino acids to help the hair growth. Iam waiting for some of supplements so we will see! I will post the results here after 3 weeks!
What do you think?
I got rash all over my body and went to the doctor and she says it is fungal infection and gave me a cream since last year am not feeling better is becoming worst each day. Can I use apple cider vinegar and how? Should I drink or apply it on my skin? Please help