DHEA for vaginal atrophy: Several ladies have posted that when applied vaginally DHEA does not get into the bloodstream and acts only on local tissue.. 2.5 mg mixed with coconut oil triggered migraine consistently after 2 days' use. I infer from this that it does indeed get into the bloodstream. So beware, ladies, as whatever the benefits, the possible side effects listed on sites such as the respected Mayo Clinic can be serious and include hormone sensitive cancers.
TEN MILE, TN
Thank you everyone for this great thread. I am having great (and quick! ) success with the 2.5mg DHEA pill and suppository combo. I'm looking forward to sharing my results with my doctor.
Hi to all on the thread.
Thank you to all for your input, it has been wonderful to read about everyones experience with DHEA. like everyone else I did not want to use an oestrogen supplement for a prolapse and dry vagina.
This lead me to do a great deal of research on DHEA, which I then presented to my doctor with all the findings. Fortunately for me she knows me well and knows how thoroughly I research. We jointly had conversations with a local compounding pharmacy in Brisbane Australia that found a formula for DHEA suppositories 3.25mg (which was what I requested) they formulated a vaginal cream to insert with an applicator and also a refrigerated product to be inserted like a tampon. I have experimented with both of these and they both work extremely well. I am coming up to my third month with nightly doses. I found relief within one week when I started, no more burning and itching, and dryness is no more. The plus is that libido has increased. I am reporting back to my doctor next week and the great thing is that he is totally open to recommending to other women. Hope this helps any other Australians feeling the frustration.
Chinderah, Nsw, Australia
DHEA: Huge success. Here are the details - I ordered 2 items, from Vitacost online. DHEA tablets: Manufacturer is Douglas Laboratories DHEA Micronized 5mg. I split them in l/2, using a single edge blade or a pill cutter (from online drug store). Also ordered the Carlson Key-E suppositories. Separately, I googled 'vaginal suppository plastic applicator', and figured out where to get them. Even if you have to purchase a product 'off the shelf', to get the applicator - go for it. Let the flat end of the suppository, get a bit 'softish'. You can do this, by just holding your fingertip on the end, for art 15 seconds. Insert the suppository 'pointed end FIRST', so that when it is in the applicator, you are looking at the 'flat' end of the suppository. Take the l/2 of the DHEA tablet, and gently push it into the softened end of the suppository. It is MUCH easier, to have it all in the plastic applicator. If you need a little 'help' getting the applicator inside - use a bit of lubricant on the outside of the applicator. After act 5 days, I did not need any lubricant. This is MUCH easier, than melting the suppositories, and trying to mix up the l/2 of the DHEA pill, etc. The newly FDA approved DHEA suppositories called, 'IntraRosa', are too expensive for me. Murry Avenue Apothecary online, also has them; again, too expensive for me - but may be an option for a lot of you. Best regards.
Hi all, I really would like to order these DHAE cubes but shipping it to Europe is quite expensive. Does anyone know if I can get this anywhere in Europe? I cannot find it on the Internet. I really would be very thankful.
Tn / Usa
El Paso Tx
Hi, over time did you continue using DHEA? Did it affect your fibroids? I've just been told by a compounding pharmacist that DHEA breaks down into estradiol which concerns me. Any insight would be greatly recommended as I'm deciding upon which treatment to embark upon.
I have been using the DHEA supositories and I can't believe the difference. I am a 60 year old woman and I was about to give up sex it hurt and I had lost the desire. Well I feel like this is the magic bullet. I actually feel like a woman again. I know that sounds corny but the DHEA I got from a compounding pharmacy they are little cubes and I cut them in half , they were prescribed, a full one was to much, I started to spot a trace and he told me to cut it in half. Perfect for me. I have moisture and plumpness and a sex drive. I can't believe it has taken me this long to find something natural that works. I don't find it messy and it didn't keep me up at night. Good Luck Ladies
I understand DHEA vaginal suppositories have yet to be approved by FDA (in third phase trial study). Those who have been using DHEA vaginal suppositories...can you tell me if you have experienced any side effects? Also, where do you purchase them if the product has not been approved?
I had vaginal atrophy so bad sex became out of the question. I tried everything. Even forced myself to use hormone creams they made me feel terrible. They made me feel extremely grouchy. I even tried using progesterone cream vaginally. My husband was supportive, but it still felt painful. I read about using dhea in the suppository. So I tried it. This is what I do. I use the Carlson suppositories and cut them in half and and hollow a little spot out for 1/3 of a 5 mg tablet. I started with a half and it was too strong- I am pretty sensitive. I insert this every other morning. I wish I could do it at night, but the dhea keeps me awake. On the days I do not do this I use 1/2 suppository at night - just helps keep things moisturized. I have been doing this for six months and I am amazed sometimes I do not even need to use a suppository prior to intercourse. I would have never even tried it before. This is the answer for me. I normally don't write about this, but I hope it helps someone.
Ten Mile, Tn
Los Angeles, Ca
I'm 60 and I have a histroy of fibroids and bioidentical hormone replacement. To make a long story short, I went off all hormones about 1 1/2 years ago (except for progesterone cream). Hot flashes, night sweats, and vaginal atrophy. So I got on vaginal estriol oil, which worked well until about 3 months ago when I started spotting. Went off of it and--vaginal atrophy again with painful sex, but the spotting cleared up right away.
But I have found something. DHEA inserted vaginally. I am well lubricated and it does not hurt to have sex. I bought some DHEA, 5 mg. Then I break the tablet into four pieces with a pill splitter. So I am getting a little over 1mg which is enough vaginally. Also, it does to systemic because my skin is significantly oilier. I have been on this for about six weeks with no spotting (estrogen makes my fibroids grow).
Some people say DHEA converts to estrogen and testosterone. I do not know yet if it is converting to estrogen, but my body will tell me. So with that in mind, it probably would not be good for someone with cancer or who is prone to cancer. I would say to ask your doctor, but doctors generally don't know any more about this sort of thing than a fly knows about computer programming.
Cambridge, Oh, Guernsey
Newman Grove, Ne
Cambridge, Oh, Guernsey
After much research, incredible stress and absolutely no help from traditional MD gynecologists, I found a compounding pharmacy that makes DHEA 3.25mg suppositories in a solid oil type base. I have used them for 1 year now and they have worked wonders for me! My only complaint is that they can be messy since the oil melts at body temperature and will leak out a little. But that is nothing compared to what I was going through before I used them.
My recent physical and blood tests, with a new doctor, showed great improvement in hormone levels and the pap smear came back showing not as much menopausal cellular changes. Some states require a prescription for the compounded suppositories and some do not. You will have to check in your area with a compounding pharmacy to see what the laws are. There are some compounding pharmacies on line that will ship out of state. There is one in Ohio that I use that is excellent. They ship the suppositories packed in ice packs and I haven't had any problems with that. But I live in the next state over so not an extreme distance away.
I finally found a local Osteophathic woman doctor that has been a true Godsend to me. She also prescribes a compounded progesterone cream based on my blood test. I have gone to MD gynecologists all my adult life will never go to one again. The extent of their knowledge for this condition seem to be to prescribe synthetic estrogen, and if you refuse that, recommend you get counseling and suggest an antidepressant medication. I am in no way a depressed person, I was stressed out from all the anxiety they helped cause me with their attitudes and lack of caring. Good luck and God Bless you all, I know how awful and stressful the symptoms of vaginal atrophy can be.
El Paso, Tx
I'm so happy to find this site. I'm in menopause and just turned 50. I'm also a newlywed. On our wedding night I experienced painful sex for the first time ever! We abstained from sex for a month before our wedding. Nobody ever told me that could bring on vaginal atrophy! I never even heard of this term! I didn't realize I had vaginal dryness. I saw my Gyno and she told me this. I just started using bio identical Estradol cream. I'm on day 4 and I can tell it's helping. I'm hopeful it will reverse the atrophy and I can have sex with my new husband soon without any pain. It's crazy that this issue hasn't been talked about more! None of my friends had heard about what could happen as we age either.
Ladies, plz keep sharing it is simply good to know you're not alone. I feel so alone in all this. Reading tips and things to try really helps. I will and will continue to try these tips. I do a lot of my own research but this really helps with ideas and things that have helped other women. Perennial massage seems to help loosen things. Will keep trying this. Plz keep sharing, this page is refreshing.
I have tried to find topics on tightening the vagina but I have never found any. If kegel's exercises are not working what else may I use. I gave birth to four kids the natural way. Please may you cover that topic because I do live on natural remedies and any other suggestions you may give me.
Manganui, Northland, New Zealand
Hi, I'm new to Earthclinic and I was totally dumfounded to read that some docs prescribe estrogens stronger than Estriol for vaginal atrophy. Estriol is the weakest of the 3 types of body estrogens and according to my OB GYN, the safest... Especially if you've had cancer. He also said that an estrogen stronger than estriol is overkill for vaginal atrophy. Know your body and take time to do your research!
Total Hysterectomy in 2001... uterine cancer.
Fact: I'm allergic to aloe vera and discovered that some of the compounds I tried contained aloe vera. So, I am going through the "process of elimination" to discover what is causing the irritation. Also, I do not want a "delivery" cream that contains paraffin, or alcohol. A delivery system can be 2 or 3 creams or a gel that is mixed with the estriol power (USP) to deliver via plunger.
I begain researching the contents of these creams and below is my findings w/ comments.
The 1st cream I tried.
USP Estriol and Vanicream (messy). Vanicream is an OTC cream.
After prices skyrocketed with my old pharmacy under new management, I switched pharmacies. So far, they are working with me, as noted below:
First compound from new pharmacy:
cream from MEDISCA and
a vanishing cream (?)
The cream did not absorb well and it caused a mild burning sensation... Vaginal walls got dry and thin... Sensation was like the beginning of a urinary tract infection
cream from MEDISCA (ingredients: Deionized water, Caprylic/Capric Triglyceride, Laureth-7, Potassium Sorbate, Phenoxyethanol, Aloe Barbadensis Leaf Juice, Polyacrylamide, C13-14 Isoparaffin, Tocophyeryl Acetate), and
Vanicream (continues to be messy)
Cream, still, was not being absorbed well - and burning continued. So, I asked the new pharmacy for the list of MEDISCA ingredients... Also, went to doc to rule out U. Tract infection.
Eliminated MEDISCA and Vanicream. MEDISCA contains aloe vera, and paraffins.
Currently, I'm trying
USP estriol and
Versabase gel (Ingredients: purified water, ammonium acryloyldimethyltaurate/VP copolymer, aloe vera, edetate disodium, allantoin, methylchloroisithiazolinone/methylisothiazolinone (preservatives)
I'm still in the trial stages of the gel. It's too early to draw a conclusion that the atrophy has been eliminated. I'm not aware of any burning sensation.
FYI: Another pharmacist I spoke with said that after hearing my HRT history, a suppository would work better.
I'll continued on with my research.
Good luck to you.