★★★★★
Vitamin B6 toxicity can occur from long-term, high-dose supplementation, not usually from food sources alone.Symptoms include peripheral neuropathy (numbness, tingling, pain in hands and feet), ataxia (loss of balance), and muscle weakness.
MTHFR polymorphisms ( which I have) can potentially affect how the body uses vitamin B6, possibly leading to both deficiency and, in some cases, an increased risk of toxicity. Specifically, individuals with MTHFR polymorphisms may experience disruptions in the conversion of pyridoxine (B6) to its active form, PLP. This can lead to apparent high levels of B6 in the blood, even with a true cellular deficiency, or make it harder for the body to properly utilize the vitamin.
So before trying to treat your peripheral neuropathy check your vitamin B6.
