Melatonin Treatment for COPD

| Modified on Nov 01, 2023
Melatonin Dosage for COPD
Posted by Marynrandy (Mesa, AZ) on 11/01/2023

I was reading Art Solbrig's article on Melatonin for COPD. He takes over 100 mg a night. In the article, it says to help with COPD, take 1 mg per kg of weight. Has anyone tried this and had any good results. That seems like a high dose of melatonin. I would need 72 mg. I have taken 5 mg but had very bad dreams. Has anyone else had this happen to them or do the dreams get better after taking for a while?

Melatonin Dosage for COPD
Posted by Art (California) on 09/04/2023 2076 posts


I only suggest melatonin during daylight hours for very serious health conditions such as cancer or Covid-19 and this is not to say that COPD is not a serious health condition, it is, but I would only consider daytime melatonin for later stage COPD.

I would limit melatonin for night time use. I think that 3 mg melatonin may be insufficient for COPD and highly recommend that you consider higher dosing if you tolerate such.. The Eleuthero root (Siberian Ginseng) is useful. The ginseng leaf is too. The downside is if you limit melatonin use to night use only, you don't get as much benefit from the ginseng components or the vitamin E during the day since they are combined with the melatonin, for the COPD, but overall the combination should be useful during the night if the dosing levels are high enough, in which case it would be a good idea to add a supplement or two during the day. Melatonin is not only good for COPD, but it also shows benefit against cardiovascular disease (CVD) and osteoporosis which people with COPD are at increased risk for. If you are unable to tolerate melatonin, the studies below may interest you.

There are quite a few supplements that are suggested to help COPD and vitamin D would be one of those that has shown benefit for people with COPD and would be taken during the day. The following study discusses the effects of vitamin D use for COPD :

Here is a relevant study quote :

' In conclusion, VDD(vitamin D deficiency was found to be ubiquitous in patients with early COPD and positively correlated with FEV1pred% and FEV1/FVC. Accordingly, this study offers experimental rationales for the role of vit D in the prevention and control of COPD and the potential anti-inflammatory mechanisms involved. '

Based on the above study, I highly recommend that you have your doctor help you to get your vitamin D level well into the upper half of the reference range which is 30 to 100 ng/ml, in order for you to take full advantage of the benefits of vitamin D for COPD. I think 5000 iu per day is what your doctor may have you start at and then retest after a few months to see if a dose adjustment is needed.

Two more of those supplements that have shown benefit for COPD is NAC in combination with Propolis from honeybees. The following study discusses this combination and how it benefits people with COPD :

Here are two relevant study quotes :

' Compared to placebo, the relative risk for exacerbation was 0.29 in AS-600 and 0.13 in AS-1, 200. No adverse events related to the treatment were reported. '

' Oral combination of natural propolis with NAC confirmed formulation efficiency with a favorable safety profile. '

So the use of Propolis at 160 mg/day plus NAC at 1200 mg/day did significantly better than the lower dose group.

These studies give you a little more food for thought in your treatment plans for COPD. It is worth repeating that people with COPD are at increased risk for CVD and osteoporosis/osteopenia. On that not,e here are links to articles I have written on these two health topics and what may help :


Melatonin Dosage for COPD
Posted by Linda (Cortland, NY, USA) on 09/04/2023

Thank you for all your hard work! Can you take Melatonin during the day? Or only at night? I have Nature's Sunshine products and they have Melatonin Extra, 3 mg, which has extra Vitamin E, Eleuthero Root, and Ginseng Leaf in it. Would love your feedback on this.

Where to Buy: UK
Posted by Dene (Uk) on 08/23/2023

You can get 10mg and possibly 12mg melatonin from delivery is quite quick. I wish you well.

Melatonin Dosage for COPD
Posted by Dana (California) on 03/17/2021

I saw in the study that the control group received 3Mg of melatonin.

'Thirty-six consecutive patients with clinically stable moderate to very severe COPD (30 men; mean±S.D.=66.6±7.8yr) were randomized to receive 3mg melatonin (N=18) or placebo for 3 months. In summary, melatonin administration reduced oxidative stress and improved dyspnea in COPD.'

Melatonin Dosage for COPD
Posted by Gary G. (Living in the Philippines ) on 02/21/2021

Hello, did you ever find an answer to the dosage of melatonin for copd? I'm also looking for an answer to that... Thanks, Gary G

Where to Buy: UK
Posted by Art (California) on 02/13/2021 2076 posts

Hi Moira,

Here on the other side of the pond, sellers sell it over the counter with no prescription needed. In your neck of the woods, it looks like Ebay UK sells the melatonin capsules & gummies. Here are a few sellers of melatonin for your consideration :

Overall, the pricing seems very good and it seems there are plenty of resellers of melatonin on Ebay UK. Good luck, Moira!


Where to Buy: UK
Posted by Moira (UK) on 02/13/2021

I found Art´s article on melatonin for COPD very useful but I am a little confused abut the dosage. In the UK you can only buy up to 3 mg. dosage at the most. Would this amount be any use to me as I have emphysema? I can order from America but not sure customs would allow a higher dose in to UK.

Melatonin Dosage for COPD
Posted by Vlii (Oregon) on 02/09/2021

Hi Art,

What is the recommended dosage and frequency of melatonin for COPD treatment?