Five years ago, while I was in my early 20's, I went to the doctor to get a Kenalog shot hoping that it would help relieve my chronic allergy symptoms (sneezing, rashes, etc.) to animals and pet dander. While there, an assistant administered the injection to my right buttock area near the sciatic nerve. I can't remember exactly how long it took, but within a couple of days to a week the tissue around where the shot was given turned purple and seemed to cave inward in the shape of an inverted cone. The area of this purplish necrotic tissue was about 2 inches in diameter. At first I thought this was a severe bruise, so I chose to ignore it for a while, hoping it would heal on its own. I experienced local pain and also pain that shot down my leg at random times while walking, which I believe was caused by the close proximity to the sciatic nerve. After a couple months of no improvement I went back to the doctor. While there I was told that there was nothing that could be done and that I might have the wound for the rest of my life. After hearing this I stopped looking for a cure. Luckily, six months after receiving the injection, someone suggested that I try massaging arnica gel into the wound 3 times a day for 5 minutes while thinking positive thoughts until it healed. I didn't use a specific dose, just enough to cover the surface area and I remember that a little bit went a long way. At first rubbing the wound was very painful, but I persisted. Within a month the cavity filled in, my skin returned to it's normal color,the pain went away, and it was as if I had never had the wound in the first place. To this day, it has remained fully healed and I am grateful. This experience has led me to look into many more natural remedies whenever I have an issue, many of which I find right here on earthclinic.com. Thanks, EC for such a wonderful site. I hope this helps someone else who may be looking for an answer.