Anal Fissures: Man, these are painful! I had no idea. It was extremely uncomfortable to sit or walk for a week or two. I tried lots of things. MSM, B6, horse chestnut and sitz baths are some I would definitely recommend. But what really sped up the healing process for me was making a paste consisting of manuka honey, turmeric and golden seal (I bought these in capsules and emptied them out). There isn't an exact ratio to the mixture, just make it thick enough to stay put. I applied this twice a day or as often as needed (after showers, bathroom etc... ) It really worked. Also, eating mostly raw foods and drinking lots of water are essential to healing. Keep that ph up. Hope this helps.