I experienced a terrible interior and exterior fissures after a 3-1/2 week of menopausal bleeding. My naturalpath recommended 'rectal rockets'. If you search on the net and read a funny account, don't believe it, they do work and not anything like the over exaggerated account, but after the 1st one, I noticed my ankles had slightly swollen; the 2nd suppository, my ankles were huge. Edema isn't one of the side effects but decided to not use the 3rd. Instead, I used an oral syringe with a tip that is about 3", filled it with aloe vera gel and slightly inserted into the rectal canal. It worked magic. Hate to admit it but the generic of neosporin healed the outside overnight. Definitely clean after each bm, preferably without toilet paper which seems to be one of the culprits. An expensive temporary handheld showerhead is worth its weight in gold for a quick clean without irritation.