[YEA] Recently diagnosed. Location in anal area, on chest, stomach, and legs. Oh holy night the Chronic anal itching during day is terrible!!! The SEVERE, wake me up, loss of sleep, night itch... makes me want to scream into my pillow and cry. Wait I have done that!!!! Punctured a COQ10 softgel and placed directly on anal affected area at 7:00 a.m. (Warning!!!! ' it Burned like hell but I felt instant itch relief. Burning sensation lasted 10 minutes) Just for testing purposes, I placed it again at 5:00 (still burned but way less this time) It is now 9:19, not one time did I have to sneak off into the bathroom at work to scratch and I have been laying in bed for over an hour without a hint of an itch. Crossing fingers (haven't had a solid night's sleep in 14 months & I hope this allows me to sleep through the night)!