Anal Itch finally gone. I am 46 and have had the miserable itch since I was 18 years old. I would be embarrassed to tell you everything I have tried but finally found a solution. DESITIN cream (used on baby butts to prevent rash). This is a thick cream that I use once each morning. All the other creams disolve throughout the day or when you wipe and the itch quickly returns. I have gone from feeling like I have poison ivy to forgetting there was ever an itch. I would have paid $1,000 dollars for a remedy but this really works. Good luck.