[WARNING!] I bought Sam-e for the depression I have had for so 30 years. I got a little headache from it and then I became dizzy. I thought because it was working on my brain already. I read the ingredients and was surprised to see it had Tosylate disulfate. Which is connected to sulpha or sulphur.
I am very allergic to Sulpha drugs and about a half hour later I started to itch. I called the pharmacist where I live and explained to her what it had. She said it would only have a minute amount in it but to get benadryl if I had any side effects. I started to feel needle like picks all over my body and took care of it with the benadryl. Maybe it won't happen to you but be careful.