Sodium Thiosulfate - Editor's Choice

Over the years, Earth Clinic readers have sent us many reports about their treatments for Sodium Thiosulfate. The editors at Earth Clinic consider the below posts to be some of the most helpful and informative and have named them 'Editor's Choice'. We hope that you will find this useful.

Sodium Thiosulfate + Ascorbic Acid Protocol

Posted by Bill (Philippines) on 08/19/2022
★★★★★

I'm just going to talk about my own recent experience of using the Sodium Thiosulfate + Ascorbic Acid protocol that Tony Pantalleresco advises. This protocol can be used against many serious problems -- including Lupus, Morgellon's, Lyme disease, Candida, SIBO, IBS, Crohn's disease, Ulcerative colitis etc. To keep the explanations simple and brief, this protocol should be used for all diseases or problems whose core origins are suspected to be in the intestines.

The reason I decided to use this protocol is because I was having excessive intestinal gas or bloating every day. It was quite unpleasant and there were times when my intestinal bloating from the gas interfered with my breathing, sometimes making me short of breath. So I decided to concentrate all efforts on killing off all the bad bacteria or whatever that was causing the unpleasant intestinal bloatedness.

Initially, I tried several other methods before using and adapting Tony's protocol. I tried using various other laxatives to clear out my intestine, including Milk of Magnesia and Pepto-Bismol. I even tried an anti-parasitic -- Ivermectin (human form) -- all to no avail.

I ended up using a modified form of Tony Pantalleresco's Ascorbic acid + Sodium Thiosulfate protocol. Tony's protocol involves taking the protocol just before going to bed. This meant that you would have to quickly get up in the middle of the night and perhaps sprint to the toilet for a rather explosive diarrhetic poop! Well that could get very messy! Nope, I don't like anything interfering with my sleep. So I modified the daytime use protocol, which is described below.

  • I get up at 6:00 am in the morning. First thing, I immediately take this protocol: Add exactly 3 ounces of mineral water(at room temperature) into a glass. Add one rounded teaspoon of sodium thiosulfate crystals and then add one rounded teaspoon of Ascorbic acid(not Sodium Ascorbate) and stir gently until dissolved.
  • Drink the mixture down in one. It will taste and smell awful(because of ascorbic acid sourness and because of the hydrogen sulfide gas that is generated by ST).
  • Have a coffee or a cup of tea. Sit near a toilet and read the papers.
  • In 2 or 3 hours you will probably have an explosive, diarrhetic poop!
  • Later that day take probiotics with meals and be sure to re-mineralize every day using sea salt and/or liquid mineral supplements.
  • Tony says that You can take his protocol every day for a month only. I only took the protocol everyday for two weeks and I have decided on having at least two weeks off the protocol to help re-establish the intestinal microbiota.


It's also quite well-known that sodium thiosulfate(ST) is quite safe to use at dosages of between 1 to 3 teaspoons a day. The Material Safety Datasheet(MSDS) for ST is 2,000 mgs/kg for a Rat(Oral) which means that sodium thiosulfate has the same or similar toxicity profile as common table salt. ST is also commonly used by modern doctors in large IV dosages as an anti-dote for arsenic and cyanide poisoning.

Since I determined that all my unpleasant intestinal gas problems were caused by bad gut bacteria and since ST is a known anti-fungal, anti-bacterial, anti-parasitic and anti-biofilm -- that's really why I decided to take it in large doses to help clear out all the bad bacteria causing my awful bloatedness. The other advantage of using ST was that it is so poorly absorbed into the blood from the intestines. When ingested, only between 5% to 8% ST is absorbed into the blood. So if we assume 8% then fora 4 gm dose (1 teaspoon) then only 4000 x 8/100 = 320 mgs is actually absorbed into the blood, which is a small and fairly safe amount.

My current status is that I came off this protocol after taking it for about two weeks and all the intestinal bloating and gas is now gone and I feel so much better. I can breath easier again because nothing is pressing up against my diaphragm anymore. Not sure if it's a cure yet but I'll keep you posted. I will probably have another two week spell using my version of the protocol to make absolutely sure that the bacteria causing the intestinal bloat is gone for good. I've also noticed that this ST protocol will also help you lose weight(I have certainly lost a few pounds over that two week period).

My own appraisal as to why this ST + AA protocol worked so well was probably due to it's anti-biotic, anti-fungal and anti-bofilm capability. As well, ST also detoxes heavy metals and also dissolves calcium, which aids in removing biofilm and also acts to help remove faeces that has been impacted and hardened on the inner intestinal walls over the years. So the ST protocol should actually have the same or similar effect over time as a colon cleanse in helping to remove all the old and impacted faeces and microbials hiding therein.

I'll post more results from this protocol when I can.


Sodium Thiosulfate Dosage

Posted by Bill (San Fernando, Philippines) on 11/10/2014
★★★★★

You can supplement one crystal of sodium thiosulfate -- about the size of a grain of rice -- mixed in a glass of water and drink that. This is what Ted from Bangkok recommends.

You can also measure out and make a 10% water solution of sodium thiosulfate and just take 6 to 10 drops of that solution in a glass of water on a daily basis.

I use the 10% sodium thiosulfate solution which I bought from an aquatics or aquaculture shop. This has served me well for many years. I've always found sodium thiosulfate easy to take with no problems. But Ted warns that, the first time you take the sodium thiosulfate, you may well get diarrhea and after that no more diarrhea. Sodium thiosulfate not only removes heavy metals but also removes cyanide, arsenic and chlorine so it is highly useful for the body. I've also found that taking ST also helps me to sleep as well, very relaxing. That's why I usually take it at night before bed.


Heavy Metal Removal, Insomnia

Posted by Bill Thompson (San Fernando, La Union) on 07/21/2011
★★★★★

I have been using Sodium Thiosulphate for a number of years now.

I use it to remove heavy metals and as an anti-oxidant to help me sleep and it works pretty well. I believe its fairly hard avoiding processed foods and water nowadays, so this is one of the reasons I take it regularly.

I take about 8 drops a day in water -- I have the 10% Sodium Thiosulphate solution sold for fish tanks. But Ted describes that he takes the flakes -- he takes one flake of ST -- about the size of a grain of rice -- in water.

I also eat cilantro or coriander leaf in salads and drink green tea regularly which also helps to remove heavy metals. Sodium Thiosulphate is also used in much larger amounts as an IV buffer or flush after a cancer patient has had chemotherapy. Sodium Thiosulphate also removes arsenic as well as cyanide from the body. Very useful stuff.

Supplementing Lugol's Iodine (Aqueous Iodine) has similar action, but acts to remove Fluorine and Bromine from the body. It also removes mercury, lead, cadmium and aluminium too.

To make the 10% ST solution, just add 10 grams Sodium Thiosulfate to 90 grams (ratio 1:9) of water and you will have the 10% solution so you can use drops if you want.


Cyanide Poisoning, Heavy Metals, Liver Poisoning

Posted by Ted (Bangkok, Thailand) on 09/16/2007 391 posts
★★★★★

Sodium thiosulfate is a common dechlorinator used to remove chlorine from drinking water. It is also a well known antidote for cyanide poisoning where the sodium thiosulfate reacts with cyanide to form sodium thiocyanate.

Some people who take too much apricot pits (cancer treatment) have a weak form of cyanide poisoning and found it helpful to add the sodium thiosulfate drops to reduced its side effect when they used the apricot pits, which is high in vitamin B17 or sometimes take apple seeds also somewhat high B17 to treat themselves of cancer or other immunity problems.

They have reported to me that the side effects were reduced from taking too much apricot pits, and caused them to be to nauseated, but when sodium thiosulfate drops are taken, no nausea effects from too much apricot pits is seen. Apparently the extra cyanide, if it were to exist in excess, reacted with sodium thiosulfate to form sodium thiocyanate, where the body can get rid of them quickly, but I also suspect that the sodium thiocyanate may have some antiviral, anti-cancer properties, perhaps only a tiny amount from eating apricot pits and the thiosulfate reduced effect, but its reacted components may have the same properties nonetheless. I would therefore imagine that the thiocyanate is less toxic than the apricot pits but also reduces the side effects by allowing the body to rid of them easier.

For me I used sodium thiosulfate to get rid of certain heavy metals, and accumulation of oxidative chemicals in the liver, as the sodium thiosulfate is a good reducing agent (reduces free radicals), but it is also a laxative in some respects, at least only initially in detoxification.

Most people are not aware that sodium thiosulfate is a common dechlorinator used in fish tanks, drinking water and swimming pool water, and sometimes a low amount of can be found in natural hot springs water, but they do have trace sodium sulfide too, which is why it can used to treat skin problems and some to bathe in it to relieved them of skin problems, rheumatism, although indirectly.

In other cases I used s.t. to help with sleep, as the reducing agent, especially the thiosulfate form of reducing agents helps with the sleep.

A thiosulfate form can form a weak sulfide compound which is also a component that works synergistically with the body's available nitrites to help to small extent anyway in controlling blood pressure or extend its effect for some people who take nitroglycerine tablets to treat both heart problems and high blood pressure. The effect is seen to last longer.

In my personal observation a bicarbonate formula, in alkaline form mixed with a very tiny amount of sodium nitrites works the same way based on my experiment as both the nitrogylcerine and the sodium nitrite degrades to nitric oxide in presence of organic acids. Interestingly, if the body were already suffering the acidosis conditions from lack of bicarbonates, the nitric oxide, which is the major component in controlling the body's blood pressure, does not degrade, and is more effective in killing of microbes, where its waste product, and the microbe itself are rich in organic acid. The sodium nitrite, produced by the body's own glial cells located in the brain, would degrade to nitric oxide, burning the acid forming bacteria, viruses and other microbes, much like burning them alive.

The sodium thiosulfate is also used as a photographic fixer, known as "Hypo" to prevent the chemicals of photgraphs from further getting dark and fix the pictures, much like a preservative, from preventing the pictures to be developed from further chemical oxidation.

I have also used it in the past to help sleep as well as to help concentration in event of ADHD, children's hyperactivity, and temper tantrums, and have worked remarkably well especially when a child of hyperactivity, is used to treat glutamine (amino acid) to help detoxify ammonia, and helped with brain development, is used in combination with sodium thiosulfate to reduced the resultant temporary hyperactivity that resulted from glutamine use. When those are used in combination, I have noted to cause a child to improve in leaps and bounds, which can be used for ADHD, hyperactivity, autism, and even emotional disturbances. For me, I also used s.t. as an anti-depressant and anxiety problems as well. At least for me anyway, the sodium thiosulfate has wide use, because of its unique properties as a reductant agent, it reduces free radicals, and reduces the liver accumulating actions of oxidative chemicals, where it is most dramatic as a treatment for cyanide poisoning. Still its everyday use is seen in fish aquariums and a dechlorinator for both drinking water and in use of swimming pools. In my opinion, people who used public bath cause their body to accumulate excess chlorine, the people who sells chlorine knows how much a human body uptake chlorine, which is quite a bit, but also does damages to the body. As a result, some people, like me for example, might after exposure to too much chlorinated water, will use the sodium thiosulfate solution to rinse by body of excess chlorine and perhaps some drops of sodium thiosulfate taken internally. Chickens and livestocks cannot use chlorinated water to chickens and pigs, as chlorinated water causes stunting of growth in pigs and chickens. At least in the case of chickens drinking water chlorinated in the farm, the biopsy of chicken were shown to have heart disease, and perhaps this line of chlorinated water used can be extended to human use as well. Of course human water, with chlorine and fluorine uses, is quite toxic to animals, and it is part of the many reasons why humans get sick. I imagine that the sodium thiosulfate to have much more wider use in the distant future and I have only begin to touch only just a small part of this, and not just its ability to remove heavy metals, chlorine, toxic compounds, excess cyanide, its anti-anxiety, anti-depressant effect, promotes sleep, is a laxative, used as a skin problems such as eczmea, and many other applications, I simply can't remember. There was one case of a child who reportedly got fat from swimming in a chlorinated water too long (for about a month) as the oxidative effect of chlorine tend to do that, and well at least help reduce those effect and at the very least, reduce being bloated, as the sodium thiosulfate would react with the excess blood chlorine to form a simple trace amounts of saline solution in very minute amounts instead of a more toxic chlorine.

The sodium thiosulfate is also used as a common remedy to reduce the side effects which causes deafness in some people from chemotherapy. But in my opinion, the free radicals also generated during x ray therapies, such as CAT scans can reduced such side effects just the same. I had a friend of mine who got a terrible headaches after getting her teeth x-rayed and took both vitamin C and sodium thiosulfate. Those two things stopped the headaches (and hopefully the radiation damages to her brain) the same day. It's probably the antioxidant effects from both the vitamin C and the sodium thiosulfate.

All this information I am telling is really old information (about 30+ years ago) as I found this out while doing experiments in U.S. high school. Nevertheless, with the trend in dumbing down of U.S. schools, I doubt any high school student today who studied chemistry would be aware of this as they are just too busy cramming for exams instead of doing experiments and make small discoveries for themselves. It was about the same time I think that Bill Gates was also playing computer programming at his own high school, which might be a monopoly program simulation, before becoming the world's largest software house.