Nattokinase for Deep Vein Thrombosis and Blood Clots

| Modified on May 22, 2023

8 User Reviews

Posted by DENISE (IN) on 01/31/2022
5 out of 5 stars

I've been using nattokinase for clots for over 20 years, just take 1 before bed. This was suggested by a holistic doc.

Replied by Antonio

Hi Denise,

I had blood clots in my lower leg and was put on blood thinners so I'm now taking Nattokinase for less than a month. I'd love to hear from you about your experience, dosages, etc.

Many thanks

God bless

Replied by Paul
(Sutherlin, Or)

Should Nattokinase be taken on an empty stomach? I know some people taking it with a meal.

Posted by Koy (Sofia) on 04/11/2021
5 out of 5 stars

For blood clots, the best probably is nattokinase (standardized enzyme from fermented soy, used in Japan for hundreds of years. I'm using it daily for years instead of prescribed blood thinners and it is life saver for me. You can find it on Amazon. Best!

Posted by Sharon (Traverse City, MI) on 12/06/2020
1 out of 5 stars

I took Nattokinase 100 mg 3 times a day and got a blood clot in my femoral artery. It didn't work for me. I didn't want to take Coumadin, that's why I took it.

Replied by LinSimon
(Tallahassee, FL)

For some people, nattokinase will not work with food. If it isn't working, try taking at bedtime or 2 hours after eating. Some also suggest it is more effective when taken with serrapeptase.

Replied by David
(Mississauga, Ontario)

I was reading a study today that has good results for preventative management of cardiovascular issues at a dose of 10,800 FU daily... perhaps with the severity of your condition, a higher dosage is required. I would look into it.


Replied by Katzie
(Cancun, Mexico)

Well, 10,800 FU didn't work, so I would try something else. DMSO is a blood thinner and a solvent - so using a natural product derived from a tree sure would be a lot healthier than 10,800fu of anything big harma could make! There are many threads on here!

Posted by Kroks (Europe) on 11/30/2020
5 out of 5 stars

3x100 mg daily, fantastic for dissolving blood cloths (9 years ago I had DVT with completely closed main vein, after 3 months my vein was app. 90-95% opened) and very good for improving general blood circulation.

I recommended nattokinase to a friend who probably had asymptomatic COVID-19 and subsequently probably micro-clots. After only 10 days he noticed better blood circulation, improved respiration and decreased chronic bronchitis and chronic sinusitis.

Posted by Ingrid (Tampa, Florida) on 10/10/2008
5 out of 5 stars

Nattokinase is known for dissolving blood clots - It is suppose to do a better (HEALTHIER) job than the chemical drugs such as Coumadin and Warfarin but nobody has been able to tell me what dosage to take. I am currently on 12mg of Warfarin for a Trombal vein blood clot and want to switch to Nattokinase asap but need to know the dosage to take?? Thanks in advance for the info.

The following info I copied from Wikkipedia :

Nattokinase is an enzyme extracted and purified from a Japanese food called Natto. Natto is a cheese-like food made from fermented soybeans that has been eaten in Japan for many years. It is thought by some to be a valuable tool in minimizing the chances of developing heart and vascular diseases. Natto is produced by fermentation by adding the bacterium Bacillus natto, a beneficial bacteria, to boiled soybeans. The resulting nattokinase enzyme is produced when the bacterium acts on the soybeans. While other soy foods contain enzymes, it is only the natto preparation that contains the specific nattokinase enzyme. Nattokinase is valued in the alternative medicine community as a clot-buster and blood thinner, and is sometimes recommended as a substitute for daily aspirin therapy. But it's effects go beyond that in terms of catalyzing other enzyme activity.

Replied by rideronthestorm54
(Grand Junction, CO)
5 out of 5 stars

I have researsched the natto and it was recommended to take a dose of 2000fui to help with blood clots.

Replied by Priscilla
(Santa Barbara County, Ca, Usa)
5 out of 5 stars

Study performed and proven effective. It worked for my mother's blood clot and varicose stasis condition in her ankle she had for ten years and nothing else worked but but Nattokinase and this particular studied product Nattokinase and pine bark. It contains studied and proven dosage of 3650 FU of Nattokinase.


Hi There,

could you provide the product you took? I would like to try it as doc believes I am at risk of Blood clots. Many thanks

Replied by Jayna D.
(Orange County, Southern California)
5 out of 5 stars

I have been taking Doctor's Best Nattokinase 2000 FUs capsules two times daily, one in a.m. and one before bed (not with food.) I have found this brand reliable and have been taking it since March of 2022. Pharmaceutical drug blood thinners can be dangerous and are from toxic materials like pork and rat poison! I was diagnosed with extensive blood clotting in my left leg in January, 2022. Ultrasounds now show great improvement. Soon after I started taking this, vein congesting near my left ankle disappeared. I also take Solaray Cool Cayenne capsules, Ginger capsules, Butcher's Broom, Horse Chestnut, and Omega 3 capsules to improve blood flow. All of these can come from Swanson Vitamins.