Flax seed use with Prostate Cancer:
This question is for Ted-
My father has prostate cancer, he had the HIFU treatment last year. His PSA was just done and has jumped from 1.4 to 10.7 in just 3 months. In November 2008, I encouraged him to start taking ground flax seed meal daily. I have recently read conflicting articles on the use of flax seed meal with prostate problems (estrogen). I'm thinking maybe the flax seed is responsible for the recent elevated PSA? I'm hoping you could shed some light on that. He also currently takes Vit C, D3, E, fish oil, selenium. He is drinking ACV and alkaline water (bought an alkalizer). I need to harp on him for his sweet tooth, so I'm sure there is a candida issue.
My brother has Prostate glands problem, please advice, what herbal could do to alleviate/cure the ailment?
Saw Palmetto and Goldenseal
I'm interested in hearing from anyone who has had experience with h202 and a high psa or prostate cancer. Thanks, Chet
Dear Earthclinic Family,
My husband, only 48, has had his Total Free PSA Level test come back with a high level 5.something (I just got off the phone with him and he was upset and couldn't remember the exact number.) His doc says there is a 50/50 chance he has prostate cancer and has scheduled him for a biopsy in one week.
We could really use some advice from any of you that have had experience personally or professionally with this type of problem. I am going to research this on the net, but maybe some of you can help with the following questions:
1. What are the risks of a biopsy?
2. How accurate are these biopsies?
3. If the biopsy confirms cancer, what next? I know the conventional way is to cut, burn or poison. What advice do you veterans of this disease have for us? If you want to write me directly, I have provided my email, just pull out the slashes.
We appreciate any prayers, good thoughts or advice you can spare.
Thank you, Sandy
Jerry -- Thank you for your response. I think you are totally correct about a person being their own advocate. Also there are so many prostate cancer books and articles out there that a person could drown in them all.
After much frenzied research, we decided to wait on the biopsy and even Dr. C. (who recommended the biopsy) told us we have some time before we need to do this. (Dr. C. said if cancer was found he would recommend taking the prostate out.)From what we have read, a biopsy may spread cancer and the biopsy procedure for prostate is more invasive and therefore riskier than other biopsies. No one told us that there are many factors that can affect a PSA test, including sexual activity, bike riding, etc and even a prostate exam!
We had another appointment with an alternative Dr., Dr. E. He believes that my husband's Vitamin D level is low and believes that could be part of the problem. He went ahead and put my husband on Cipro to see if that will lower the PSA, as the other doc (Dr. C, the doctor who wanted to biopsy) did not even mention the possibility of prostatitus.(My husband had a vasectomy in July and we have read that sometimes prostatitus can occur after this.) My husband went ahead and had blood drawn to check on his Vitamin D levels and will see Dr. E this week to go over the results. Dr. E also started him on a mix of three herbs (saw palmetto, stinging nettle, & pygeum).
Dr. E said that what Dr. C did is standard practice and my husband and I totally understand that he must follow procedure to avoid being sued.
So, we are going to try and change my husband's PSA levels over the next couple of months and if there is no response, we will have the Doppler ultrasound and go from there.
We will keep you posted. Thanks again, Sandy
Hello Sandy, My fiancee's PSA test was recently at 8.0. When he was originally diagnosed with a "suspicious prostate" over ten years ago his PSA was above 5.0. He had biopsies both times -- the results were negative. You're correct when you say that high PSA levels can be attributed to a variety of conditions other than cancer. Enlarged prostates can become problematic as you get older and interfere with the ability to urinate, which can lead to other complications (bladder infection, kidney problems). The good news is, your husband is young and still has the opportunity to modify his diet and impact the health of his prostate and overall well-being. Research shows that men who eat Western diets (high meat & dairy consumption) have higher incidences of prostate problems and cancer--my physician friends have substantiated this. My fiancee recently cut out all dairy, red meat and coffee and is already noticing positive results. As an aside, Saw Palmetto and Pygeum have been extensively researched in Europe as effective ways to treat enlarged prostates. That said, there's a plethora of information available on the Web and it can quickly become overwhelming. If your budget allows, I would recommend seeing a nutritionist or naturopath with experience in prostate care. It will be well worth your investment. I wish you and your husband all the best.
Recently I was told by a Holistic Health practitioner that an herbal formula called, Zyflamend was great for arthritis.I was surprised that within 2 days I felt a dramatic difference, my pain was taken from an 8 on the pain scale to about a 3! What a blessing! I use 2 zyflamend a day and when my pain is really bad I use 3-4. I also read online that Zyflamend has been studied by Columbia University on Prostate Cancer. I guess when you calm inflammation a lot of good things happen in the body.
EC: Reported Side Effects for Zyflamend include heart palpitations and dizziness. Please research before you buy!
* Rosemary, (leaf), 100 mg supercritical extract and 50 mg extract (23% total phenolic antioxidants [TPA]-34.5 mg) 150 mg |
*Turmeric, (rhizome), 10 mg supercritical extract (45% turmerones-4.5 mg) and 100 mg ethanolic extract (7% curcuminoids-7 mg) 110 mg *Ginger, (rhizome), 54 mg supercritical extract (30% pungent compounds-16.2mg, 8% zingiberene-4.3 mg) and 46 mg ethanolic extract (3% pungent compounds-1.4 mg) 100 mg
* Holy Basil, (leaf), extract (2% ursolic acid-2 mg) 100 mg
* Green Tea, (leaf), extract (45% polyphenols-45 mg)(contains 10 mg naturally occurring caffeine- 1/10 coffee cup equivalent) 100 mg
* Hu Zhang, (Polygonum cuspidatum), (root and rhizome), extract, (8% resveratrol-6.4 mg) 80 mg
* Chinese Goldthread, (root), extract (6% berberine-2.4 mg) 40 mg
* Barberry, (root), extract (6% berberine-2.4 mg) 40 mg
* Oregano, (leaf), supercritical extract (0.8% TPA-.32 mg) 40 mg
* Baikal Skullcap, (Scutellaria baicalensis), (root) hydroethanolic extract (17-26% baicalein complex, including baicalein and baicalin -3.4-5.2 mg, and 0.4-0.9% wogonin - 0.08-0.18 mg)
HI VERNON, FROM SALEM OREGON! Your posting caught my attention when I was browsing for something about prostate cancer. I have a friend who has a prostate cancer, and I want to help. Do you think a lot of people especially men - would benefit if you would post your treatment option here? I AM VERY INTERESTED. PLEASE HELP! I want to help my friend.
Dear Vernon, Please let me know what was "another substance" you were taking for the metastatic prostate cancer. I have the same diagnosed with metastatic prostate cancer. I am looking forward your reply.
For the prostate cancer questions with blackstrap MOLASSES.. The 1 to 1 ratio of I teaspoon of blackstrap molasses and 1 of soda... How many times a day? or just once?
Prostate Tumor Formula
Mortie, Can you please tell me where I can find this prostate formula?
Hi Paul, I am a 48 year old thats been suffering with prostate issue for a long time and I saw your meassage on Cayenne pepper and that you are a naturopahtic healer and would apprieate it if I could talk to you about my prostate issue. My prostate keeps me up at night because I can't empty my bladder. thanks
Please I want more information on how to use cayenne pepper to reduce my enlarged prostrate gland. At the age of 67, I have enlarged prostrate gland and for the past three(3) months have been catheter. I spent 3 weeks at a sanitorium in Nigeia and was discharged against my will because I desire to leave there with a reduced prostrate gland. I don't want to go for surgery though sometime I bleed just a little. My PSA is 4.0. Please help me with proven cures using cayenne pepper with or without other natural herbs.
I don't know the efficacy of humic acid. But I've heard that saw palmetto, pygeum, and stinging nettle are herbs that can help with prostate health problems. Even green tea helps because it's rich in antioxidants. There's a product that contains Beta Sitosterol, an ester that's clinically proven to promote prostate health. In my opinion though, it's safer to talk to a healthcare professional before taking any herbs or other supplements, especially if you aren't sure about their usefulness!
I have had a PSA jump from 6 to 25 in two months 2.5 years after radiation and implant therapy. Want to know about cayenne pepper as a possible therapy
I had severe acid reflux and ulcers. I took mastic gum by Now co. There are other companies too. I took capsules. It WILL cure both ailments,but you must keep taking it until you get symptons vanish -of course! It has been shown to fight prostate cancer. See net for tests and research. Great substance if one stays with it. A million times better than baking soda!
I found that I could buy cheap Mastic gum online by looking for the greek version of this which is used in their recipes. 50grams for AUD$28. They call it "mastiha" powder and add it to a range of things, including alcohol.. but mastiha powder is the same thing.
H Pylori is known to cause colon cancer, it is possible that it may be causing prostate cancer too.
For years I have tolerated growing onslaught of misinformation about Soy even though most studies relating to soy is quite positive. Today, I am angry and decided to post this myself.
If you don't believe me that soy is good for you, you don't have to! You can prove this for yourself! I will tell you how! The secret is here.
Do this: go to www.pubmed.org and do a search using the following keyword as follows:
- soy cancer
- soy dht
- soy testosterone
- soy estrogen
- soy osteoporosis
You will then learn the truth and you don't even have to believe me. I have done this for you already, and here are the summaries in case you don't have time! True information that I will post the research citations verbatim directly from research studies as follows:
1. DHT hormones (dihydrotestosterone) are the major cause of male hormone baldness. When lack of testosterone does not generate that much DHT stays on your head. The only known substance to reduce that is DHT.
2. Phytoestrogen has no effect on estrogen levels or hormone levels or even testosterone.
3. Soy helps with osteoporosis.
4. Soy reduces cancer and is used to treat cancer victims.
I will post the medical abstracts verbatim below.
Now the reason why such a relentless attack on soy is that there are ulterior motives from certain interest groups such as
1. Decreasing milk cows sales.
2. the use of genetically modified cows
3. the use of bovine growth hormones injected into cows which we drink and may cause obesity
4. The prevalence of mad cow's disease
5. The findings of a chemical toxins and toxic vaccines and might be found in cow's milk.
I am an Asian, here where I live we actually consume more soy milk then even fermented soy products. And it has kept us relatively low of osteoporosis.
Because of so much bombardment against soy, I will not put any thing here besides research abstract below. Ted"
Nope: soy does not effect testosterone:
Serum prostate-specific antigen but not testosterone levels decrease in a randomized soy intervention among men.
Maskarinec G, Morimoto Y, Hebshi S, Sharma S, Franke AA, Stanczyk FZ.
1Cancer Research Center of Hawaii, University of Hawaii, Honolulu, HI, USA.
Background: Low prostate cancer incidence and high soy intake in Asian countries suggest a possible protective effect of soy foods against prostate cancer. The goal of this pilot study was to evaluate the feasibility of a randomized, crossover soy trial among men and to investigate the effects of daily soy intake on serum prostate-specific antigen (PSA) and testosterone levels.Methods:We randomized 24 men to a high or a low soy diet for 3 months. After a 1-month washout period, the men crossed over to the other treatment. During the high soy diet, the men consumed two daily soy servings; during the low soy diet, they maintained their usual diet. During the entire study each man donated four blood samples and five overnight urine samples. Dietary compliance was assessed by soy calendars, 24-h dietary recalls, and urinary isoflavone excretion measured by high-pressure liquid chromatography with photodiode array detection. Blood samples were analyzed for serum testosterone and PSA by radioimmunoassay. When necessary, variables were log transformed. Two sample t-tests compared the two groups before each study period. Mixed models incorporating the repeated measurements were used to evaluate the effect of the soy diet on urinary isoflavone excretion and serum analytes.Results:Twenty-three men aged 58.7+/-7.2 years completed the study. The compliance with the study regimen was high according to self-reported soy food intake and urinary isoflavone excretion. No significant between-group and within-group differences were detected. During the high soy diet, dietary isoflavone intake and urinary isoflavone excretion increased significantly as compared to the low soy diet. A 14% decline in serum PSA levels (P=0.10), but no change in testosterone (P=0.70), was observed during the high soy diet in contrast to the low soy diet.Conclusion:The high adherence as shown by three measures of compliance in this pilot trial demonstrated the feasibility of an intervention based on soy foods among free-living men.European Journal of Clinical Nutrition advance online publication, 14 June 2006; doi:10.1038/sj.ejcn.1602473.
PMID: 16775579 [PubMed - as supplied by publisher]
Asians have less osteporosis because of soy milk consumption! We consume more soy milk then the so called fermented things that Dr. Mercola claims!
Osteoporosis prevention education programme for women. Chan MF, Ko CY.
School of Nursing, The Hong Kong Polytechnic University, Hung Hom, Hong Kong SAR, China. [email protected]
AIM: This paper reports an evaluation of a nurse-initiated education programme on four specific osteoporosis prevention behaviours which led to their adoption or to positive attitude changes.
BACKGROUND: In the past, osteoporosis was a serious health concern that most commonly affected women in Northern Europe and the United States of America, but was less commonly seen in Asian women. However, in Hong Kong, osteoporosis is currently among the top five conditions causing disability and prolonged hospital stay for older people. From an economic perspective, the most cost-effective approach is to focus on primary prevention via education, and nurses often have the responsibility of providing such educational programmes.
METHOD: A randomized controlled study was conducted from July 2004 to March 2005 with 76 women (38 cases and 38 controls) recruited in two private beauty clinics in Hong Kong. Pre-, post- and follow-up education data were compared regarding attitudes and adoption frequency before and after the education programme. RESULTS: The results showed statistically significant increases for each behaviour: consumption of soy foods (P < 0.001), milk (P < 0.001), more exercise (P = 0.01) and vitamin D/exposure to sunlight (P < 0.001) for the case group compared with the control group. Most participants either disagreed (n = 15, 39.0%) or strongly disagreed (n = 23, 61.0%) that there was not enough information provided in the education programme to motivate them to change. They rated the nurse's performance as either satisfactory or very satisfactory on presentation, ability to answer their questions and ability to describe each behaviour clearly.
CONCLUSION: Although positive results with a nurse-initiated education programme were demonstrated, future research examining the effects of education and occupation on these four adoption behaviours should focus on more diverse populations with respect to age, income or ethnicity. The findings suggest the value of creative approaches in future health education for the prevention of osteoporosis, and the need for a critical appraisal of current strategies and a re-evaluation of services and funding.
PMID: 16553702 [PubMed - in process]
A rat study confirms improved bone when fed with soy
Soy affects trabecular microarchitecture and favorably alters select bone-specific gene expressions in a male rat model of osteoporosis.
Soung DY, Devareddy L, Khalil DA, Hooshmand S, Patade A, Lucas EA, Arjmandi BH.
Department of Nutrition, Food & Exercise Sciences, Florida State University, 436 Sandels Bldg, Tallahassee, Florida, 32306-1493, USA, [email protected].
We have recently reported that soy isoflavones particularly when provided in the context of soy protein are capable of preventing loss of bone mineral density due to orchidectomy in F344 rats. We hypothesize, that soy isoflavones also exert beneficial effects on bone microstructural properties, in part, by enhancing bone formation. Therefore, in the present study, we examined the dose-dependent effects of soy isoflavones on femoral bone microarchitectural properties and select bone-specific gene expressions in the same rat model. Seventy-two, 13-month old rats were either orchidectomized (ORX; 5 groups) or sham-operated (Sham; 1 group) and immediately placed on dietary treatments for 180 days. Four of the ORX groups were fed either casein- or soy protein-based diets each with one of two doses of isoflavones either 600 or 1200 mg/kg diet. Rats in the remaining ORX control and Sham groups were fed a control casein-based diet. Soy protein at the high isoflavone dose, and to a lesser extent with the lower dose, reduced the magnitude of the ORX-induced decreases in trabecular bone volume (BV/TV) and trabecular number (Th.N) and increase in trabecular separation (Tb.Sp) at the femoral neck site. These modulations of trabecular microstructural properties by isoflavones may be due to increased mRNA levels of alkaline phosphatase (ALP), collagen type I (COL), and osteocalcin (OC), which are associated with enhanced bone formation. These findings confirm our earlier observations that the modest bone protective effects of soy isoflavones are due to increased rate of bone formation.
PMID: 16830200 [PubMed - in process
Soy reduces dangerous DHT that causes you to go bald But yet had no effect on good hormones!
1: J Nutr. 2005 Mar;135(3):584-91.
Soy protein isolates of varying isoflavone content exert minor effects on serum reproductive hormones in healthy young men.
Dillingham BL, McVeigh BL, Lampe JW, Duncan AM.
Department of Human Biology and Nutritional Sciences, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
Inverse associations between soy and prostate cancer and the contribution of hormones to prostate cancer prompted the current study to determine whether soy protein could alter serum hormones in men. Thirty-five men consumed milk protein isolate (MPI), low-isoflavone soy protein isolate (SPI) (low-iso SPI; 1.64 +/- 0.19 mg isoflavones/d), and high-iso SPI (61.7 +/- 7.35 mg isoflavones/d) for 57 d each in a randomized crossover design. Twenty-four-hour urine samples indicated that urinary isoflavones were significantly increased by the high-iso SPI relative to the low-iso SPI and MPI. Serum collected on d 1, 29, and 57 of each treatment revealed that dihydrotestosterone (DHT) and DHT/testosterone were significantly decreased by the low-iso SPI [9.4% (P = 0.036) and 9.0% (P = 0.004), respectively] and the high-iso SPI [15% (P = 0.047) and 14% (P = 0.013), respectively], compared with the MPI at d 57. Other significant effects included a decrease in testosterone by the low-iso SPI relative to the MPI (P = 0.023) and high-iso SPI (P = 0.020) at d 29; an increase in dehydroepiandrosterone sulfate by the low-iso SPI relative to the MPI at d 29 (P = 0.001) and relative to the MPI (P = 0.0003) and high-iso SPI (P = 0.005) at d 57; and increases in estradiol and estrone by the low-iso SPI relative to the MPI at d 57 (P = 0.010 and P = 0.005, respectively). In conclusion, soy protein, regardless of isoflavone content, decreased DHT and DHT/testosterone with minor effects on other hormones, providing evidence for some effects of soy protein on hormones. The relevance of the magnitude of these effects to future prostate cancer risk requires further investigation.
PMID: 15735098 [PubMed - indexed for MEDLINE]
Soy is used in cancer treatment!! Cancer causing? You have been lied to by the Cow's milk consortium! Yes it protects against Prostate Cancer!
Effects of a diet rich in phytoestrogens on prostate-specific antigen and sex hormones in men diagnosed with prostate cancer.
Dalais FS, Meliala A, Wattanapenpaiboon N, Frydenberg M, Suter DA, Thomson WK, Wahlqvist ML.
International Health and Development Unit, Monash University, Clayton, VIC, Australia.
OBJECTIVES: To determine the effects of diets rich in soy and linseed compared with a control diet on biochemical markers of prostate cancer in men diagnosed with prostate cancer. METHODS: Twenty-nine men diagnosed with prostate cancer and scheduled to undergo a radical prostatectomy were randomized to one of three groups: soy (high phytoestrogen), soy and linseed (high phytoestrogen), or wheat (low phytoestrogen). A bread was specially manufactured to incorporate 50 g of heat-treated (HT) soy grits or 50 g of HT soy grits and 20 g of linseed as part of the study participant's daily diet. Baseline and preoperative levels of prostate-specific antigen (PSA), free PSA, testosterone, sex hormone-binding globulin, free androgen index, and dihydrotestosterone were measured. RESULTS: Statistically significant differences were detected between the HT soy grits group and the control wheat group for the percentage of change in total PSA (-12.7% versus 40%, P = 0.02) and the percentage of change in free/total PSA ratio (27.4% versus -15.6%, P = 0.01); and between the HT soy grits group and the HT soy grits and linseed group for the percentage of change in free androgen index (16.4% versus -15.5%, P = 0.04) and the percentage of change in free/total PSA ratio (27.4% versus -10%, P = 0.007). CONCLUSIONS: The data from this study indicate that a daily diet containing four slices of a bread rich in HT soy grits favorably influences the PSA level and the free/total PSA ratio in patients with prostate cancer. This work provides some evidence to support epidemiologic studies claiming that male populations who consume high phytoestrogen diets have a reduced risk of prostate cancer development and progression.
PMID: 15351581 [PubMed - indexed for MEDLINE]
Genistein and daizein is o.k.
Genistein and daidzein downregulate prostate androgen-regulated transcript-1 (PART-1) gene expression induced by dihydrotestosterone in human prostate LNCaP cancer cells. Yu L, Blackburn GL, Zhou JR.
Nutrition/Metabolism Laboratory, Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.
Epidemiologic investigations and laboratory studies suggest that bioactive soy phytochemical components may be used as an effective dietary regimen for prevention of prostate cancer. Studies designed to identify new genes that are responsive to androgens and are sensitive to the prevention of prostate cancer using soy bioactive components have become a research priority. In this study, we determined the effect of soy isoflavones on the expression of prostate androgen-regulated transcript 1 (PART-1), a newly discovered androgen-induced gene that may represent a novel androgen-dependent prostate cancer tumor marker. In an androgen-depleted cell culture system, 5alpha-dihydrotestosterone (DHT) induced expression of PART-1 transcript in androgen-sensitive LNCaP, but not in androgen-independent DU 145 or PC-3 human prostate cancer cells. The soy isoflavones genistein and daidzein dose-dependently inhibited DHT-induced expression of the PART-1 transcript. Genistein at 50 micro mol/L completely inhibited expression of the PART-1 transcript in LNCaP cells induced by DHT at 0.1 and 1.0 nmol/L. Daidzein was less potent than genistein, whereas glycitein at the same levels as genistein or daidzein did not inhibit DHT-induced PART-1 transcript expression. Our studies suggest that use of the PART-1 gene as a biomarker for evaluating the efficacy of soy isoflavones on androgen-dependent prostate cancer warrants further investigation.
PMID: 12566472 [PubMed - indexed for MEDLINE]
9/16/2007: Alan from Ann Arbor, Michigan writes: http://grouppekurosawa.com/blog/2005/12/curcumin-preparation-and.htm
Wednesday, December 07, 2005
Curcumin Preparation and Bioavailability
Curcumin is getting lots of scientific interest these days. Every month additional scientific studies are published on the effects of curcumin on different biochemical pathways.
Just keep one thing in mind. The curcumin used in these laboratory studies was dissolved in alcohol or DMSO. In short, the curcumin was made soluble in certain solvents that do not translate well for introduction into the human body.
The following two papers studied the effects of 3.6 grams of oral curcumin, in capsules, on humans. The first study is quite clear that curcumin simply does not enter the body in sufficient quantities to be medically effective.
In this study, oral doses of 3.6 grams of curcumin a day showed blood levels of 10nM. This is a VERY low concentration of curcumin. Yet, it was apparently enough to reduce prostaglandin E2 synthesis in colon cancer patients.
In order for curcumin to be maximally effective against cancer, it MUST be introduced into the body in a bioavailable form. Curcumin is almost totally insoluble in water. On the other hand, it is completely soluble in fat.
Curcumin dissolves readily in coconut milk or cream, especially if they are warm. There is NO reason to boil coconut milk or cream in order to dissolve curcumin. Never boil anything unless you are absolutely certain the heat will not damage the medicinal properties of the natural medicine. I have no idea how heat stable curcumin is for medicinal purposes. So don't boil it.
Curcumin that is dissolved in fat will be introduced into the lymphatic system with the fat. There is exactly where we want curcumin to be introduced into the body. The lymphatic fluid bathes all the tissues in the body. We are NOT interested in directly introducing it into the blood.
People complain about the taste of curcumin. So add other spices, such as turmeric, or other spices to the mix to change the taste.
How much curcumin do we need to treat cancer and leukemia? No one knows but I would recommend at least 10 grams a day, 5 grams twice a day dissolved in fat. Since curcumin is not toxic, why screw around with low doses?
You must use glutamine, at least 20 grams a day, with the curcumin to make it maximally effective. I blogged on this issue yesterday.