I have had some success. I had a large stone 2.1 cm in 2011 and the Dr said it was up to me if I wanted to get my gb removed. He said a large stone only puts pressure on the duct, but wont get stuck in it. I already knew I would opt for surgery anyway since the gb is very important! I called my naturopath up and she suggested I drink a very warm glass of water with the juice of a yellow lemon every morning on an empty stomach. This thins the bile. A few days later my pain was gone. I then did a liver flush with some herbs, cascara sagrada and beet root formula. Followed with olive oil and gIrapefruit juice. Didn't notice too much difference from that, but I'm sure it helped. I changed my diet to include plenty of fats (i eat eggs over easy, avocados, cheese, meat, butter, coconut oil, olive oil, etc. ) and eliminated grains and most sugars. I supplemented daily with sunflower lethicin, magnesium, vitamins, and drank my lemon water every morning. In 2012 I had a second ultrasound done on my gallbladder and the stone was 40% dissolved. My doctor was in disbelief to say the least! He told me he had really doubted me in going a natural route but that he is happy I have done so well. I no longer have pain so I'm anxiously awaiting my upcoming scan this summer to see what's left!