★★★★★
My friend asked me if I had any suggestions for the DPN and I suggested he try Melatonin Gel (MG) directly to painful areas and areas where he felt movement restriction. I further told him that the MG should help to alleviate the pain and improve his range of motion. I gave him a 3 ounce bottle of MG and I suggested application 2 or 3 times a day applied sparingly to the affected areas and he said he would start immediately. Normally I would have only suggested 2 applications per day, but he told me he has been taking melatonin gummies for at least two years and has a very high tolerance for melatonin, so I told him 3 times a day should not be a problem.
I talked with him recently and he said the MG is really helping. He said it has reduced the pain and made it possible for him to resume his exercise program again! He is very happy about the MG and so I explained to him how to make it at home. He said he applies it 3 times a day and it makes his days much easier!
I further told him that MG is not just a pain reliever, but that studies show that melatonin also helps repair the damaged nerves while promoting nerve regeneration and being able to do his exercise regimen again will also contribute to nerve regeneration. Here is a link discussing the nerve repair effects from melatonin :
https://pmc.ncbi.nlm.nih.gov/articles/PMC9470957/
Here are two relevant quotes from the link :
' According to in vivo findings, melatonin treatment reduces DN via inhibition of oxidative stress and inflammatory pathways. However, compared to the diabetes groups alone, melatonin treatment exhibited an anti-oxidant trend. According to other research, DN also significantly produces biochemical alterations in neuron cells/tissues. Additionally, histological alterations in neuron tissue following DN were detected.'
' Nonetheless, in the majority of cases, these diabetes-induced biochemical and histological alterations were reversed when melatonin was administered. It is worth noting that the administration of melatonin ameliorates the neuropathy caused by diabetes. Melatonin exerts these neuroprotective effects via various anti-oxidant, anti-inflammatory, and other mechanisms. '
In my opinion, applying MG directly to the affected nerves allows more than high enough amounts of melatonin to be delivered where needed to affect the reparative effects mentioned in the study.
Here is a link that describes how to make melatonin gel at home yourself :
https://www.earthclinic.com/supplements/melatonin-gel.html
Here is a link that describes how to make Melatonin Lotion :
https://www.earthclinic.com/supplements/melatonin-lotion.html
My friend is using the gel as opposed to the lotion because he is applying to other areas of his body for other health issues.
Overall, he is very happy with his results so far and I have added Alpha Lipoic Acid (ALA) to his regimen to further improve his DPN status as well as help with some of his other health issues.
Art
