Glutathione
★★★★★
HI U OLE PATOOTS DOIN, ORH here and I have another yawn to spin. Getting senile, so I may have told this tale before.
My Natural Doctor uses a Glutathione IV in his treatment for folks with dementia. He is cheap by comparison, but it is over $100 a pop. I first did this and then I went to compounding and inhaling with a nebulizer. I called a few months ago and my compounding guy said Big Pharma had the rules changed so you can now only get two weeks supply at a time. They are part of the carbol that is about to fall.... along with the demons in the DUMBS.
Since I's SJS, I researched and found an L-Glutathione Plus reduced product that I could mix with saline, nebulize, and keep my brain sharp enough to stay two steps ahead of D. You can find this product on the net and it is dirt cheap. It has the same sulfur smell as my compound stuff, so I feel good about it. I can only work about a couple of hours a day at the farm, but like Wildroot Cream Oil, a little dab will do you. I think I may be able to get our garden in again this year. Hooray, we will not have to go to the PIMA camps and get the vaccine. Maybe I get to live to see the end.
ATS ===ORH===
(Ireland)
08/17/2024
Hi ORH it is a pleasure to read all of your helpful tips and tricks. I would love to chat to you through message or email and learn more from you especially about demtia and niacinamide to help my older sister who has been diagnosed with dementia is is taking that awful prescription medication. I hope this reaches you and that you are well. Love from Dublin Ireland.
Gotu Kola
★★★★★
GV-971 Seaweed
★★★★★
In China, they have been testing GV-971, which is derived from a specific form of seaweed that is abundant there, for many years for use as a treatment for AD. They have finished initial testing in China and GV-971 is now available there for people with AD. Currently, they are also doing additional testing in North America and Canada, but that testing is still ongoing. Here is a link to a description of GV-971 and what previous GV-971 studies have shown regarding its usefulness for AD :
https://www.alzdiscovery.org/uploads/cognitive_vitality_media/Sodium_Oligomannate_(GV-971).pdf
GV-971 has several methods of action, but interestingly, one of its main methods of action is manipulation of the gut microbiome to reduce neural inflammation and protect neurons, while reducing oxidative stress.
Interestingly they are just starting testing GV-971 for Parkinson's disease also as noted in this report :
This is really good news because the currently available drugs for AD are only marginally effective in mild to moderate AD and their usefulness can dwindle fairly quickly in some PD patients or offer no benefit in others. Add in the known side effects associated with one of the more common drugs in this class of drugs, Aricept, and you quickly start to realize the importance of GV-971. Here is a link to side effects seen in some Aricept users :
https://www.drugs.com/sfx/aricept-side-effects.html
It is worth noting that they are considering further studies at even higher dosing in the future to find out if higher dosing can cause further or better response in people with AD. As far as I am aware, this is the first new drug that has come available for AD in many years in the whole world. In the human trials so far for GV-971 at the currently prescribed dose, showed a safety profile similar to the placebo group. In the trials for GV-971, it showed clear and sustained benefit when compared to the placebo group from week four right through to the 32nd week or trial end.
They have not said when the US and Canadian studies will be completed, but as soon as they are, GV-971 may become a reality here once the FDA approves it. For now, China has already added it to their "National Drug Reimbursement List " (NDRL) and reduced the price by 60%. The original price was RMB 895 ($140.16 usd) and was lowered to RMB 296 ( $46.50 usd). Generally, the US pays more for pharmaceuticals, so it will likely be significantly more than these numbers when it comes available here.
Art
Betty,
It was in the first link, but here is the description :
https://en.wikipedia.org/wiki/Sodium_oligomannate
Sodium oligomannate (development code GV-971) is a mixture of oligosaccharides isolated from the marine algae Ecklonia kurome that is used in China as a treatment for Alzheimer's disease (AD).[1] It was conditionally approved in China by the National Medical Products Administration in 2019 for mild to moderate AD to improve cognitive function.[1
This form of seaweed is plentiful there.
Art
(CA)
03/22/2022
Thank you, Art! How did I miss that when it was right up front? Can I blame it on brain fatigue :)
This is a very interesting find.
(Oregon)
04/26/2023
Seaweed is a vital source of Vitamin D for vegans, so, maybe Vitamin D is crucial in as many forms as possible. Just my sidebar.
Hydrogen Peroxide
Intermittent Fasting & Low Refined Carb Diet
★★★★★
The Western diet composed of seed oils, sugar and refined carbs (also fed to patients in care homes and hospitals) may initiate dementia. Intermittent fasting, low carb, low sugar diets may prevent and hypothetically reverse dementia.
Fasting induces ketosis which reduces beta amyloid plaques and tau -
Dr Paul Mason - Reversing Dementia With Diet - A 2021 Update -
https://m.youtube.com/watch?v=muAvJ1y64PA
Finally, regular consumption of small amounts of turmeric powder may reverse dementia symptoms -
https://nutritionfacts.org/blog/can-turmeric-help-with-alzheimers/
I hope the above links can help someone.
Lemon Juice
★★★★☆
(San Antonio, Texas, Usa)
12/19/2012
Update on my Dad, its been over a week and he is doing great, my Mom is still giving him 2 lemon per day. One in the morning and the other at night. I also read Ted advise on Alzheimer's Disease and I started giving him 2 pills of Lysine in the afternoon a total of 1000 mg. Thank You Ted... Thanks, and God Blessed...
(MI)
07/08/2024
Thank you for the great info. I wonder if you dad was low on progesterone? I just saw a video by Dr. Eric Berg about the relationship between progesterone and dementia, and someone commented that vitamin C can increase progesterone a lot. Also, the relationship between melatonin and dementia, and melatonin can be increased by the infrared sunlight in morning or late afternoon.
(San Antonio, Texas,usa)
12/30/2012
Update on my Dad, he is doing great, still doing the lemon and l-lysine every day for Alzheimer's Disease. He did have a bad day so I question my Mom and she told me she had skip 3 of his lemon juice drink because she was sick and didn't give my Dad his lemon juice but was still taking the l-lysine. We put him back on the lemon juice and he was back to normal the following day. He is starting to use the phone again he had stop calling us when he was sick. He is also starting to eat some of his meal in the table. He was only eating in his chair in the lliving room. My Mom called me a few days ago and said that my Dad was doing great and she wanted to start taking the l-lysine also. So now my Dad is still at 1000 mg in the evening and my Mom is taking 500mg. Stay Blessed
(Worden, Il, Usa)
12/31/2012
Hi Mary Jane.... There is all kinds of information about Alheimer's and Virgin Coconut Oil and how much it can help.
(Appleton, Ny Usa)
01/05/2013
Mary Jane, please give more updates about your Dad. Has drinking the fresh lemon juice helped his memory at all? Have you seen any definite improvement in his memory? Any less confusion in his thinking? Thanks.
(San Antonio, Texas, Usa)
01/09/2013
01-09-13. Up date on my Dad, he is still doing very well.
Anon, First I want to tell you why I gave my Dad the lemon juice. I was searching the net for remedies for alzheimer and found a site that said Lemon Balm may improve people memory's that have alzheimers. The evening when I went over to help with my Dad so my Mom could rest and shower, he was being very mean to my Mom, and he was upset about leaving the house they had just move in, he would just keep talking about the house. My parent have not move they have lived in the same house for about 25 years. When I was there sitting in the living room with him, I remember reading about the lemon balm. I had never heard of lemon balm and didn't buy any, but I knew I had lemons so that why I use lemon. It was very upsetting to me to see and hear my Dad just losing it. My brothers and sisters were already thinking of putting him in a home since he was starting to be mean to my Mom... My Dad is 78 year old and I have never seen him be mean to her.
So to answer your question, his memory is awesome, he knows who we are, if I ask my Mom where are your scissors he will answer first and he will tell me where to find them. And again I give God all the Glory and Honor... Stay Blessed
(Appleton, Ny, Usa)
01/09/2013
Mary Jane, thank you for posting about Alzheimer's Disease. It's great that you give God the glory and honor. He is truly the source of every good gift. (John 3:16)
Maybe I'm misunderstanding, but it sounds like before you tried this treatment, your Dad was terribly confused, upset, acting mean, and his memory was very poor. And now all of these things, including even his memory, have improved dramatically??
Please continue to post any clarifications or details or developments that you think are helpful.
I'm sure many people will be reading what you're posting here. Maybe some will try the freshly squeezed lemon juice (in water, with added non-sugar sweetener) twice a day and report their results.
(San Antonio, Texas, Usa)
01/10/2013
Update on my Dad, talk to my Mom today and my Dad is doing great :)
To Anon, Yes to all your questions. And yes I hope people start trying the lemon juice on there love ones. I have told a few people that I know with family member with Alzheimer's Disease and they look at me like I'm crazy... If it helps millions of people that would be awesome but if it only help one person in this crazy world we live in that would be awesome too... Stay Blessed
(San Antonio, Texas, Usa)
02/06/2013
Update on my Dad. He is doing very well. Still giving him his lemon juice and l-lysine everyday. If my dad doesn't want to go with my mom to the store she now can leave him alone at the house for a while since he is doing great... Stay Blessed.
(Anon)
02/07/2013
Hi, Great news! I look forward to your feedback - keep up the good work.
(San Antonio, Texas, Usa)
03/14/2013
Update on my Dad, he is doing great, he turn 78 in February. He just went to his apointment 2 days ago to see his doctor. And the doctor told my dad he is doing very well and does not have to see him for another 6 months. My Dad ask if he can drive again and his doctor told him no, lol. Still giving him his l-lysine and lemon juice everyday... Stay Blessed.
(Battleground, Wash)
03/15/2013
New book at the library written by a doc who treated her hubby with coconut oil for his alzheimers... Very interesting.. Won't work for everyone but certain sugar uptake issues in the brain are healed by coconut oil added in the diet... hope this helps.
(New York, US)
09/20/2014
(Bologna - Italy)
08/02/2017
(IL)
03/22/2022
Sweet & low is a neurotoxin and should not be used. Try monk fruit powder that is pure & clean. Some companies put junk it in (alcoholic sugars ending in lol). Avoid any monk fruit powder that has junk in it.
Hi Mary Jane. I've just come across your post from 8yrs ago. I'm in need of help for my mum who's 85 and has Alzheimer's. Could you tell me if the lemon juice you used for your dad was used alongside other medications, please? If you have time to email me I would really appreciate it. Thank you, God bless.
Lion's Mane
★★★★★
Lions mane is ever more popular...more and more scientific research trundling in to support its claims. While still not mainstream I can, fingers crossed, say it is helping my Mum who has a diagnoses of mild cognitive impairment/brain disease. At the moment she is taking 4 grams a day
(LA)
09/08/2024
One needs to be careful with Lions Mane. It does not work the same for everyone and can cause an unwanted side effects. Start slow and watch. Mental agitation is one of the side effects.
Lithium Aspartate
Lithium, the rediscovered (missing?) element for your brain's regeneration
The Misunderstood Mineral
By Jonathan V. Wright, M.D.
(Reprinted From "Nutrition and Healing"
http://www.oradix.com/health-library/article.php?id=031
excerpt: There are many other research findings that also strongly suggest that lithium will protect against potential Alzheimer's disease and slow the progression of existing cases. Researchers have reported that lithium inhibits beta-amyloid secretion, and also prevents damage caused by beta-amyloid protein once it's been formed.20-23 Beta-amyloid peptide is a signature protein involved in Alzheimer's disease: the more beta-amyloid protein, the worse the Alzheimer's becomes...
Lithium Orotate - Alzheimers Disease, Aluminum, Fibromyalgia: Is There a Relationship?
http://www.smartbodyz.com/Lithium-Orotate-Alzheimers-Disease-Aluminum-Fibromyalgia-Pg2.htm
excerpt:Chris D. Meletis, N.D. reports in Vitamin Research News, "Studies show that lithium, in general, inhibits the atrophy of the hippocampus. Atrophy of the human hippocampus is seen in a variety of disorders including Alzheimer's disease."(1)
I don't like lithium aspartate it's an excitotoxin much like aspartame. It may reverse, but only temporarily. Therefore the preferred lithium needs to be lithium carbonate, lithium citrate being the safest one. Long term use does more harm in aspartate form then good. Aspartate, MSG and aspartame are all excitotoxin. The beta amyloid is a toxicity of high level exposure of metal zinc, and hence 1000 mg of L carnosine and some small amounts of EDTA to remove zinc, as well as other metals is the cause of the alzheimer. Scientist found beta amyloid removes heavy metals, but in excess, beta amyloid becomes a problem. Therefore it makes more sense to use those that gives energy to the brain without the excitotoxins such as drops of methylene blue which is protective of the cell's mitochrondria systems, and the removal of heavy metals such as cilantro and carnosine and perhaps drops of sodium thiosulfate, or even chlorella to help remove the heavy metals. Potassium citrate will further alkalize the brain so the brain can heal. i don't believe in lithium aspartate because I have received several years ago that while initially it helped alzheimer, the condition later on became progressively much worse. It was from the excitotoxin of the aspartate.
Ted
(NY, NY)
02/10/2009
thank you so much for your imput, I'm really looking for personal experiences before use it and your comment is of great help. nevertheless i'd like to deep more into this issue.
lithium carbonate is more toxic, it needs high levels in order to cross the brain barrier.
if lithium aspartate has that toxic effect, what is your experience with lithium orotate?
Low dosages of lithium have been found to be safe.[9] Dr. Jonathan Wright suggests 20 to 30 mg. of lithium aspartate or lithium orotate daily as an appropriate dose to stop brain aging. This is 1/3 to 1/6 the dosage of lithium carbonate used to treat manic depressive disorder. Dr. Hans Nieper of Germany has learned that lithium orotate or lithium aspartate penetrate cells more effectively than lithium carbonate so smaller doses can be used. One tablespoon of flaxseed oil daily along with 400 I.U. of vitamin E ensures that no lithium toxicity can develop
HOW TO ENLARGE YOUR BRAIN AND IMPROVE BRAIN PERFORMANCE
By Dr. James Howenstine, MD.
May 5, 2004
NewsWithViews.com
http://www.newswithviews.com/Howenstine/james11.htm
recent research has shown that low doses of lithium preserve and renew[1] brain cells. Eight of ten persons given lithium showed an increase in brain grey matter of 3 % after only 4 weeks. By promoting brain cell regeneration and increasing brain size lithium can function as an anti-aging nutrient for the brain.
Lithium also accomplishes the following benefits for brain cells:
*
Lithium enhances DNA replication which is the first step to formation of new cells.
*
The damaging effects of excitotoxins. (monosodium glutamate (MSG), aspartame (Nutrasweet) etc. can be blocked by lithium.[2]
*
Animal research shows that lithium can decrease the areas of cell death after induced strokes by 56 %.
*
Lithium protects rat brain cells from the. increased levels of brain cell death caused by anti-convulsant drugs (Dilantin phenytoin , Tegretol, carbamazepine etc.)
*
Lithium may protect against adverse effects from mood altering drugs, alcohol, tobacco, caffeine, 'uppers"and "downers", and marihuana all of which cause brain damage with long term use.
*
Abnormally functioning signaling pathways may become repaired by lithium.
*
The aluminum felt to be a possible cause of Alzheimer's Disease (AD). is chelated[3] by lithium so it can be more easily removed from the body.
Research has suggested that lithium blocks the secretion of beta-amyloid in Alzheimer's disease and prevents damage from pre-existing beta amyloid. Overactivity of the brain cell protein tau contributes to death of neurones in Alzheimer's Disease. Lithium inhibits this tau protein damage and the formation of the neurofibrillary tangles seen in AD.
I'm looking for natural neurogenesis boosters, like THC from hemp, but it is illegal in US.
(Florence, Al)
11/01/2011
(Sydney, New South Wales, Australia)
12/04/2012
Melatonin
★★★★★
https://pubmed.ncbi.nlm.nih.gov/39886794/
Here is a very relevant quote from the literature review :
' The neuroprotective, anti-inflammatory, and antioxidant qualities of melatonin, a hormone mostly produced by the pineal gland, have drawn interest as a possible treatment option for AD. This study looks at new evidence that suggests melatonin overexpression to be a promising therapy option for AD. Melatonin levels naturally decline with age and decrease more significantly in individuals with AD, worsening neurodegenerative processes. Melatonin has therapeutic potential as it inhibits Aβ formation, prevents amyloid fibril extension through structure-dependent interactions, and protects neurons from Aβ-induced toxicity. Melatonin promotes neurogenesis, which is decreased in AD, suggesting it may treat the disease's many pathologies. The review emphasizes the importance of melatonin's mechanisms of action, including its capacity to reduce neuroinflammation, regulate mitochondrial function, scavenge free radicals, and influence apoptotic pathways. '
As you can see melatonin offers potential to fight Alzheimer's disease at many of its known activity pathways suggesting that melatonin will be very useful in many anti Alzheimer's disease regimens. Another advantage of melatonin is that it has a proven very good safety profile and with the advent of Melatonin Gel (MG) a better potential delivery method of systemic melatonin that can last approximately 24 hours whereas oral melatonin is only active for about 5 hours.
Another advantage of melatonin is that it can be very effective at ameliorating the "Sundowning" effect of agitation that comes on in the later afternoon in in many people with AD. Here is a link that gives a detailed explanation of "Sundowning".
https://www.alzheimers.org.uk/about-dementia/symptoms-and-diagnosis/symptoms/sundowning
I have seen how effective melatonin can be for sundowning and it can be a real game changer for that AD symptom alone!
Art
(America)
02/01/2025
Art, thank you for this information! I recently started adding a pinch of melatonin to my water bottle. My question is, I also add lemon juice, 1/4 tsp baking soda, pink salt, glycine, gaba, and inositol to the water, does any of this cancel out the melatonin? Thanks!
Hi Hollyhock,
There shouldn't be a problem with that mix, but if you take it near bedtime, the GABA should be additive to the melatonin in terms of sleep and relaxation.
Art
Migraines and Alzheimer's Disease
★★★★★
I was wondering if migraines might be a forewarning of future AD, and according to the following article, it definitely is with people who regularly have migraine headaches being three times more likely for men and 6 times more likely for women to get AD than non-migraine people :
Here are two very relevant quotes from this interesting article :
' A 2001 study examining the risk factors for Alzheimer's disease found that men and women with a history of migraine were three times more likely to develop AD.5 Looking at women alone, the study found that they were almost 6 times more likely to develop AD.5 '
' Another study was conducted to determine if migraine was a risk factor for dementia subtypes; Alzheimer's and vascular. The study found that a history of migraine was noted in 23.5% of participants with AD compared to 9.9% of cognitively intact participants.6 They also found that people with a history of migraine were three times more likely to have dementia than people without dementia.6 Similar to the previous study, they found that people with AD were four times more likely to have a history of migraine disease.6 Interestingly, when looking at the subtypes of dementia, they found no correlation with a history of migraine and vascular dementia.6 '
I tried to convince my friends to try alternative means of improving her situation, but my other friend, her husband, will not try any alternatives even though she is declining very rapidly. She is now so bad in just two years that she could not remember to take helpful supplements without someone giving them to her.
If you have migraines regularly, you are at increased risk for AD, especially if you are a woman. It may be worth taking steps early on to improve your chances against getting AD.
Art
(Idaho)
07/21/2023
Madelyn,
You may find this of interest :
https://www.earthclinic.com/cures/art-solbrig-protocol-for-memory-loss.html
Art
(Idaho)
07/22/2023
Most definitely! Thank you, Art!
Madelyn,
I forgot to mention that I have updated this memory regimen by dropping the Amla Extract and replacing it with Benfotiamine. Optional is to add Citicoline as it has also shown benefit in terms of memory improvement.
Art
MMS, Dietary Changes +
★★★★★
We started MMS, plant food diet, herbs, lots of water, and vitamins. He was taken off all pills and communicated with us. We did lots of our own research. That was 7 years ago. It is worth it to research everything, the truth is out there.
Music
★★★★★
We got to the living room. My kids had stringed instruments and started to play. They played some songs that I knew he loved and had been singing for more than half a century. Dad immediately perked up. He sang along, he smiled, he showed nostalgic recongnition. He even stood up and started "directing." We sang and sang and sang. He clearly enjoyed it. What was interesting is that he seemed mentally better after we had been singing. When I had arrived, I don't think he knew I was his daugther or even someone he knew. Later he was introducing me to someone as his daughter. He couldn't recal my name. I supplied it and he said, "Oh, yes, " and then he said my middle name.
I have seen music affect my babies. I have seen music help children learn to read. And I know it is powerful.
I wonder what would happen if my Dad had a lot more singing time each day.
The nursing home where he lives does work hard to cater to the needs of memory care patients. The movies they play are the oldies that most residents would rememember from younger days - lots of black and white movies, even. Every day during meal time they play "big band" music. I have often seen my dad begin to dance a little when he hears the music. He loved to dance as a younger man even taught ballroom dancing.
I know research is being done with regards to the elderly and music. I would love to understand it more. But meanwhile, I know that music helps the brain, even of those with Alzheimer's.
How to put this into practice? If you have a loved one with Alzheimer's, make a point of playing music they loved when they were younger. Sing with them, when you can. I don't think all music is equally helpful. Music is emotional - it evokes happiness, depression, anger, excitement, restlessness, peacefulness. So be mindful what the music you chose is going to promote.
I am also convinced that complex classical music does amazing things for the brain. If you do not know where to start with classical music, start with Bach. It will keep you busy for years. Play Bach for the elderly people you love. Play it for your babies and toddlers and children, too. In fact, play it for yourself. I think it is something from which everyone can benefit.
"To send light into the darkness of men's hearts, such is the duty of the artist." Robert Schumann (German composer from the 1800's).
TY Mama for sharing your commitments to your dad. Coconut Oil & healing Music will go a long way for him.
I was, not long ago, very touched to have learned that one of my favorite folk musicians Joan Baez was such a serious & professional musician as well as humanitarian. Joan, along with her sister Mimi, made big commitments to keep music personal not industrial and healing rather than recreational.
Music
Nattokinase
-------------
Alzheimer's disease occurs when there's a build-up of amyloid. Amyloid is oxidized protein. It's a waste product that builds up inside all non-dividing cells. This includes the cells in your heart, brain, kidneys, etc. It builds slowly. And it slowly shuts down the ability of your cells to properly function. It irritates them, sort of like a chigger on your skin. Your brain cells are particularly sensitive.
It's rare to find a compound that can dissolve amyloid. But recently, researchers discovered that my favorite enzyme, nattokinase, cleaves to the protein and enhances its removal. What's interesting is that other protein dissolving enzymes, including trypsin and plasmin, don't do it. Trypsin is a protein-dissolving enzyme made by your pancreas. Plasmin is a protein in your blood that dissolves clots.
Interestingly, nattokinase got its fame as a clot buster or clot preventer. Now science is showing its superiority in dissolving this other unwanted protein.
--------------
I noticed Nattokinase was missing from Earth Clinic's Alzheimer remedy list.
(Uniontown, Oh)
10/28/2013
Do you know if Serrapeptase also clears this plaque? Thank you.
(Fl)
10/29/2013
Here is a link that would support the use of both Nattokinase and Serrapeptase in rats with Alzheimers: http://www.ncbi.nlm.nih.gov/pubmed/23821590
Since Serrapeptase also has fibrolytic activity, I should have somewhat same effect on amyloid plaque. It is not as natural to the body as Nattokinase but that may be why to add it. Many supplement formulas used both to remove plaque from arteries. When one considers the list of very positive effects that these fibrolytic enzymes have on clots, heart attacks and strokes, i'd add it even if I didn't have Alzheimers especially if one is 40 years or older.
Niacin
★★★★★
I, and others, have noticed a lessening of his Alzheimer's/Dementia symptoms. He is less confused. He is sharper. As mentioned in another post, I just got back from a visit with him. We played cards. He played a spelling bee type game with my son. He would not have done these things a few months ago.
After my mother passed away four months ago, we expected my dad to decline steadily. He is doing so much better than we expected. He does have less stress now (watching your spouse die of Alzheimer's over the course of a couple of years is very stressful.) He is also getting regular exercise. Those and the niacin may all be contributing to his improved mental condition. Whatever it is, we are glad!
~Mama to Many~
(Somewhere, Europe)
08/15/2014
(Texas)
07/29/2018
Isn't (or IS) no-flush niacin the same as Niacinamide?
