[YEA] I have used neem oil very successfully to prevent head lice. My daughter caught them at school. I used an over-the-counter insecticide to kill the lice that were on her head. Then I used the special comb included with the insecticide to remove as many of the eggs as possible. Then I applied neem oil (heated until it was liquid) to her scalp, generously, then massaged her scalp to make sure the oil covered her scalp completely. After this treatment, she had no more lice. The other kids in her class continued to get lice, but she never got lice again. I understand that neem oil kills the eggs and also makes it difficult or impossible for the living lice to drink blood from the veins in the scalp, so they die without laying more eggs.