I have AS, diagnosed nearly 8 years ago. I have tried everything and stumbled upon something that has made a remarkable difference to my pain. I have been taking a supplement with vitamin d3 1000iu per tablet, boran(from borax)1mg, selenium 50mcg, and natural vitamin E 33 mg. I have been taking this supplement two mid morning and one in the afternoon. At the same time I am taking red algea (lithothamnion calcareum) 500mg, twice a day (taken at same time as red algea). Before trying this, talk to your Dr, not everyone is vitamin D difficient. I avoid the sun as I am fair skinned and burn easily.