I myself have applied GSE directly to my mouth without incident. In fact, a coworker had a mouth sore that had gotten so bad that she planned to make an ER visit the next day. I had her apply GSE directly to the sore and by the end of our 8 hour shift it was gone.
GSE (Grapefruit Seed Extract) for Strep Throat:
I absolutely love this site! One thing I haven't seen is the amazing and simple treatment for Strep Throat and several other issues. GSE (grapefruit seed extract) has kept me out of the doctors office for 13 years now. One bottle can last me at least a year or two and it only cost me $12.00. I work around germs and virus' every day (poker dealer)and use it as a preventative measure as well. Just 3-8 drops in water or juice once a day when others are getting sick, keeps everything I'm exposed to from rooting itself into my system. When I have had Strep Throat catch me off guard, I simply mega-dose by taking 13 drops in a small glass of water. Gargle and swallow. Yes, swallow. I do this 3 times a day and keep doing it even though the sore throat is gone within 12-24 hours and The white bumps within 24 -36 hours, for at least 7 days. Just like a script for antibiotics, keep going past the symptoms stage. GSE attacks germs and is even used as a dissinfectant for tooth brushes, countertops etc... It is said it is 50 times more potent than bleach against germs yet the whole bottle (hundreds of doses worth) is less toxic to the body than one baby Bayer aspirin. Google it yourself and see it does natures work like the hand of God. I read it is even effective against Anthrax?