Per your request for info re animal vaccination reactions:
My DSH [domestic short-hair feline, a b/w tuxedo female, age approx. 15 yrs. , had her first negative reaction to a vaccination. A distemper booster turned the white skin on the back of her neck black. Nothing further happened, and that condition dissipated; however, that small section is now bald. Her vet, who is very good, was alarmed by this result and checked with the manufacturer - which claimed no other such reactions. The vet entered into my cat's files: NEVER EVER AGAIN GIVE THIS CAT A DISTEMPER SHOT. FYI. Thank you for this forum.