My dog had Open Pyometra recently. I tried the Manuka Honey, Vitamin C, Turmeric, but they did not work. After doing much research I gave her the Now brand Echinacea and Goldenseal root 225/225mg blend for 2 weeks. She started to clear up within a few days and within 2 weeks was completely cured.
My dog weighs 65 pounds, and that dosage worked for her. The Echinacea boosts the immune system and the Goldenseal is an antibiotic. I gave her 1 capsule in the morning and 1 capsule in the evening. I mixed it in with a little canned food, which she loves.