Lyme Vaccine Side Effects in Dogs

| Modified on Mar 23, 2022
Add New Post Comments

Lyme Disease can be a very serious disease for dogs. A vaccine for such a feared disease is great in theory. However many, many pets have had serious side effects from the Vaccine for Lyme Disease including behavioral changes, arthritis, pain, vomiting, lethargy, loss of consciousness, and death.

Earth Clinic readers have shared many alarming stories of reactions in their dogs to the Lyme Vaccine.

Anne from Wisconsin tells us, "My vet suggested my coonhound mix, Trixie, be vaccinated for Lyme disease even though I use tick prevention all year. Within 3 days she was having trouble moving her head and neck and "screamed" if anyone bumped her. She is normally somewhat crazy, jumping and barking at everything, but she stopped barking completely."

"Maxsmom25" from UT shares that her four month old puppy had a reaction to the Lyme Vaccine, "It was terrifying. He went limp and was vomiting, luckily we were still at the vet so they were able to reverse it. But now I am terrified about going back to continue vaccinations!"

In Virginia, Pamela's 11 year old dog went lame within 24 hours of receiving the Lyme Disease Vaccine.

Should My Dog Get the Lyme Vaccine?

What is a pet owner to do? There are risks to the vaccine and risks to the disease it is meant to prevent! But pet owners do have a choice, this is not a mandatory vaccine. In areas where animals are not at risk for tick-borne disease, the risk of the disease is low. Animals that are kept indoors are at low risk, unless the pet owners bring the ticks in on their clothes. There are products to prevent ticks in animals, but these products often come with side effects, too. Happily, may pet owners have found some natural alternatives to these products.

Reducing Risks of Lyme Disease in Dogs

If you have control of your pet's outdoor area, you can work to keep the area tick-free and greatly reduce the risk of Lyme Disease without the worry of the vaccine. Keeping grass short and eliminating brushy areas helps a lot with tick problems. Some pet owners sprinkle cedar granules or diatomaceous earth in the yard to prevent ticks. This may need to be done several times during tick season.

If you do get your pet vaccinated for Lyme Disease, do not get the vaccine if your pet is ill. It is also best to only get one vaccine at a time. This makes it easier to know what vaccine is causing a problem, should your pet have a reaction.

Scroll down to read the stories about the Lyme Vaccine sent to us by Earth Clinic readers.

If your pet has experienced side effects from the Lyme Disease Vaccination, please share your experience!

Lyme Vaccination Side Effects

33 User Reviews

Posted by Candice (Wisconsin) on 03/23/2022
0 out of 5 stars

I'd give the "Lymes vaccine" shot a zero. Negative if I could.

After both of my dogs had the second shot, that very week two bloody violent fights broke out between the two and it had never happened previously in 7 years. It was the vaccine of course tormenting their brains. They also started having violence issues and barking issues. They seemed to not be able to differentiate anymore between a threat and non threat. Now they just mindlessly get angry and elevate matters. They are vaccine damaged for sure in the brain. But also in their bodies: One dog has a cancer lesion now on her nose and other weird growths that were not there previously. I tell everyone not to get this for their dogs. I even stopped one lady from getting the second shot for her beloved pet. I talk to my students and many of their dogs have had this and many of them told me that their dogs have suffered seizures since this shot. I told them to go to their vet and demand that he reports it officially with paperwork that you get a copy of.

Replied by Terri

I'm so sorry to hear this! Please give them activated charcoal to pull the toxins out of your dogs. This is heartbreaking...I'm so sorry for your dogs misery. Thank you for warning others!

Lyme Vaccination Side Effects
Posted by Kenneth (Hurricane, WV) on 02/16/2022
0 out of 5 stars

My Yorkie, had a Lyme vaccination and could barely walk the next day but was then ok, 5 days later he has had constant diarrhea and is lethargic from time to times, vet said it wasn't the vaccine and gave us Imodium but he still won't eat, very concerned.

EC: Please see this page on Earth Clinic for remedies:

Lyme Vaccination Side Effects
Posted by Candixe (Wisconsin) on 04/04/2021
0 out of 5 stars

I went to the union grove vet who I will never take my dogs to anymore in Wisconsin. The guy pushes vaccines like crazy and when I told him not to give my dog a vaccine not needed for whooping he cough, he took my dog in the back and did it anyway and then I got pissed, and he apologized. Nonetheless, since having the Lymes vaccine which was pushed on us, our dogs have never been the same. For the first time in 5 years they fought twice and the one hunting dog has been NUTS since getting it. She barks at everything and cannot calm herself down. Its like her brain is on fire. I'm really angry that the vet field is going as same as AMA with fake health via vaccines...making our animals more ill with latent viruses and god knows what else is in the vaccine. It should be law that ALL ingredients are listed just like FDA demand ingredients on packaging.

Replied by Charity
(faithville, Us)
Replied by Kerri

So sorry to hear about the damage to your dogs! Please try a little charcoal mixed in their water. You might be surprised that they prefer it. Mine do. It is worth a try...please do!

Lyme Vaccination Side Effects
Posted by Keisha (New Jersey) on 11/20/2020
0 out of 5 stars

I took my 5 month old pup to banfield for final shots they gave him the Lyme disease shot. A couple of days later I noticed he is hardly eating now 4 day after shot he has a limp. I called the vet they say to monitor it and if it gets worse they will do a check. I will not recommend this shot, not at the expense of all these side effected.

Lyme Vaccination Side Effects
Posted by Jackie Bluejacket (Afton, Ok) on 03/27/2018
0 out of 5 stars

My dog, Molly, received the Lymes vaccine along with her regular yearly vaccines on a Wednesday. Sunday evening she died! She vomited the first night, went downhill, lethargic. Diarrhea and worse lethargy. Quit eating, quit drinking and then couldn't even stand or walk without help. Now she is dead and we are heartbroken!

Lyme Vaccination Side Effects
Posted by Yvette (Yonkers, Ny ) on 03/10/2018
0 out of 5 stars

My five month old puppy received a lyme shot 10 days ago and she's limping hasn't gotten any better. I called the vet and he says not to worry it will go away but nine days after a injection and her limping is concerning to me.

I will be contacting the vet again regarding this matter it's concerning me to see my puppy limping when she wasn't before. I will not be taking her any more for any lyme shots if these are the reaction she'd going to have after the shot..

The vets will always say it's nothing to worry about it will get better or come in so we can countine to pay for nothing because what will they do so our animals will not suffer from an injection.

Not right I'm not a happy person with this situation!!!!

Lyme Vaccination Side Effects
Posted by Mike B (New Haven, Ct) on 12/17/2017
0 out of 5 stars

Hello. My 5 1/2 year old cocker spaniel was fine. Went to vet Banfield for physical, they gave her Lyme vaccine, we live in CT. That night she started changing, sluggish, not eating. This went on for 3 days. Called vet. No worries wait 5-6 days after shot, next day Riley worst, would not get up out of bed, called vet and insisted I bring her in, they denied it's the Lyme vaccine, they wanted to do more blood work etc which was just fine 3 days before, I denied the blood work, They gave her antibiotics and non steroid anti inflammatory. Still denying any issues of vaccine. Riley seemed a little better with 3 days of anti inflammatory. This morning, Riley is shaking, can't move well at all. This is 9 days after shot. She went outside but almost couldn't make it up the deck steps. She use to run and jump and be happy, now she is shaking in pain! What do we do??

Lyme Vaccination Side Effects
Posted by Jessica (Jessie) on 10/12/2017
0 out of 5 stars

Hello, my dog is a three year old lab/Shepard mix, his name is Brock. He received his booster shot for Lyme disease two days ago. Since then he is not acting like himself. He normally is at my side, he is acting scared and is off by himself. It's breaking my heart, I even tried bribing him with treats, nothing is working.

Lyme Vaccination Side Effects
Posted by Heather Sanchez (Willseyville) on 10/11/2017
0 out of 5 stars

I too my new two year old rescue dog in for a free vet check he recommended the lyne disease vaccination and after suffering with horrible Lyme disease myself bedridden for years and in wheelchair before they figured me out I jumped at this for my dog I asked if any bad side effects and if it's truly safe. One hour after the shot, she shakes and tremors in legs then bit me if I touch her backside where shot is. She won't get off couch or jump up she whining and acts in great pain. I cried when I did my research on it. OMG! What did I do to my pup. I'm so upset! This is horrible.

Lyme Vaccination Side Effects
Posted by Flynn (Butler) on 08/11/2017
0 out of 5 stars

I took my Shih Tzu to get a lymes vaccine and that evening he wouldn't eat or play. The next day same thing I called the vet they said it was not the vaccine. Day 3 still the same so I took him for an ER visit to the vet. They stuck with not the vaccine ...I paid 325.00 for blood test and visit. went home with nausea meds that did nothing. How long will it take for my Pup to feel better. We will not get round 2 of the lymes.

Replied by Theresa
(Mpls., Mn)

Hey Flynn,

You might consider homeopathic Silca for your Shih Tzu.

Lyme Vaccination Side Effects
Posted by Mariamagdalena (Las Vegas, Nevada) on 06/03/2017
0 out of 5 stars

After reading a few websites now we're convinced that our standard poodle had an allergic reaction to the shot for Lyme disease. The day after he had his shots he started not being himself. He couldn't even jump on the bed anymore and after he had a bath he was not even able to shake his body like he normally did and he stopped barking all this happen and it lasted about 1 week. He is five years, four months old and had the lyme disease shot every year for the past four years and this is the first time he had this kind of reaction but it scared us enough to where he's not going to be getting the shot ever again will just take other other precautions.

Lyme Vaccination Side Effects
Posted by Pippa (Duxbury, Ma) on 05/26/2017
0 out of 5 stars


As dog owners that have watched our pets suffer from Lyme vaccine reactions and adverse effects, we need a collection of data. The data needs to be sent to American Veterinary Medical Association, American Kennel Club. My vet "pushes" it. This year it was included in vaccines at yearly physical. I found out that they received Lyme Vaccine when I paid bill. I have two Shelties. Foxy became lame in her right front leg after vaccine 2 years in a row. It resolved. The vet insists that "this is not due to vaccine as he has never seen this reaction. The next year the same reaction happened immediately after Lyme vaccination. Foxy was not to get the vaccine again. She got it again this year without my knowledge.

Shelly ( 2nd sheltie ) this year vomited profusely in vet office after vaccine. The injection site was swollen with discharge. She cries in pain. I contacted vet and going in today. Again VET DENIES THAT LYME VACCINATION COULD DO THIS. AND YES THEY PUSH THE VACCINE AND ADAMANTLY DENY THAT IT HAS SIDE EFFECTS.


I live in New England. We camp. Use Advantix 2 and have never had a tick. Yards can be safely treated without chemicals.

Very worried about Shelly. It is as though her entire body is painful to palpation, touch. THERE NEEDS TO BE CONSUMER AWARENESS . Do veterinarians report adverse effects of medications and vaccines as doctors and hospitals do?

Replied by Julie
(Albany Ny)

I hate it when vets say effects are not related to vaccines, especially since they never saw it before. Like people, each dog is different. Pet owners need to go with their gut and common sense. I am a licensed vet tech and I know for a fact that vaccines make up a huge part of a vet's income and they don't like to admit it. DO NOT let vets push vaccines on your dog. Rabies vaccine is required by law but distemper should NOT be administered yearly after a dog has had their first set of shots and then one year after. Three or more years after that!!!

Lyme Vaccination Side Effects
Posted by Kathy (Ny) on 04/29/2017
0 out of 5 stars

My 8 month old GSD received the Lyme vaccination and within hours began limping and became lethargic. He became worse and returned to the vet the next day. He had a 106 temp and could not bear weight on his front leg. Was given an anti-inflammatory and antibiotic. It's been 2 days and he is slowly responding. Needless to say, he won't be getting the 2nd dose

Replied by Marie


I hope your puppy is doing better. We must only vaccinate for distemper, parvo, and rabies. Then, before any further vaccinations, have a blood test called a titer taken to detect immunity. Any reaction is positive for immunity, where no reaction truly shows no further immunity. Titers are acceptable in place of continuing rabies vaccinations in many states and countries now. Please go on line and watch the interview on Dr. Mercola regarding pet vaccinations. It is quite eye opening. The Lyme vaccination is a killed version of the virus so adding L-lysine daily at about 1/16th tsp powdered may help, and the homeopathic Thuya 30c 4 pellets, 3 times a day for a week. I always advise any pet owner to stay outside the vets office for an hour after any vaccination in case of shock. I learned this with my own dog. She nearly died after a neurological reaction to a rabies booster at the age of 8 in 2012, after which she became autoimmune. She was put down last year. I wish I knew this then. Good luck.

Lyme Vaccination Side Effects
Posted by Nath (New Brunswick) on 04/20/2017
0 out of 5 stars

After my yorkie had the lyme vaccine...I realize she has a hard lump at the spot of the it normal? - 2 weeks now 😢

Lyme Vaccination Side Effects
Posted by Dd (Devils Lake, Nd) on 09/29/2016
0 out of 5 stars

My Golden Retriever had the Lymes vaccine and within two days she was lethargic, crying and could not get up by herself. After taking her to the vet they gave her aspirin saying they thought it was an ACL injury. A month later she was still not well, in fact worse. We had xrays for her hips and decided it was not hip displaysa. After going to another vet they decided it was due to the Lymes vaccine. It is attacking her. Her muscles in her legs would shake and she could not get up by herself. We have put her on prednisone and she is better however when we lower the dose to 1/2 pill every other day she goes back down hill, so then we have to go back up to the previous dose of 1/2 pill every day. We don't know if she will ever get off of the Prednisone. This has been going on since April 2016 and it is now the end of September. If anyone has any suggestions I would like to hear them.

Replied by Theresa
(Mpls., Mn)

Hey Dd,

You might find a holistic vet to repair the damage. If you cannot locate a holistic vet a common remedy for vaccine damage and allergic reactions is thuja occidentalis. You can usually find thuja at most health food stores. Google on what dosing schedule applies in your particular situation.

1 2 3