Schizophrenia Remedies

| Modified on Nov 30, 2023
B-3 Vitamin Therapy
Posted by Barbara (Texas) on 04/05/2015

I just wanted to tell you. My son 25, was lost on the streets in phx. No meds, out of his mind with schizophrenia and alcohol addiction. We found him and we are doing Hoffer's advice 3000 + niacin no flush and C. He is DOING WONDERFUL. It's like night and day. His mind is back and the only struggle he has currently is the addiction, which is also helped by nicacin. This only took two weeks in our case. So please give it a try. Nothing to loose, you can't OD on it or get harmed on it. You do need to read their book. Four nobel prize winning doctors wrote that book having studied that vitamin more tha 45 years. Anyone else giving you advice better have the same or more years behind what they studied. Good luck and God bless!

B-3 Vitamin Therapy
Posted by Cordell (Minto, New Brunswick Canada) on 08/02/2010

I would like to share a remedy I successfully used to cure schizophrenic thoughts. I was always shy as a kid, and little bit "paranoid" I guess you could say. But when I turned 24 I gradually began to have more paranoia, coupled with anxiety, and sometimes felt I was hearing voices. No, not the audible kind that people usually hear, but more or less I felt there were more thoughts in my head than my own; too many to deal with at once. Some very hateful thoughts had emerged and I sometimes became obsessive over certain angry thoughts, feeling like I couldn't relax and eventually would have a panic attack and feel out of control, possibly cry from too much stimulation etc. I soon found myself trying to figure my thoughts out, but they often made no sense, and I would play psycho-analytical games with other people thinking I realy knew what they were thinking about me. I was always suspicious, and eventhough I didn't want to feel this way that's what happened. Anyway, I know there are others out there that share a similiar story: how they once felt normal than started having some sort of mental illness, be it brain fog (which I also had from the obsessive paranoia), or adhd or whatever it may be. Niacinamide could be the answer to your problems. On the advice of Ted, a famous contributor to this site, I began taking 2000mg - 3000mg of Niacinamide (niacin can be used, but the flushing may become too annoying at such doses for some people). I noticed within a couple days my excessive paranoid thoughts dimnished almost completely, but I continue to take 500mg tablets everytime I feel them coming back. I also continue to take at least one B 50 tablet a day to prevent deficiencies. It works~! I realize not every form of schizophrenic thoughts may be cured this way, but its worth a try for anyone seeking help like I did. High doses of niacinamide have cured my excessive anxiety, paranoia, schizophrenic thoughts, and even helped to solve stomach ailments I have had for years along with keeping myself more alkaline. The alkaline remedy I used with most success in over-acidity was 1/4 sodium bicarbonate, and 1/4 potassium citrate (a 99mg tablet) in a glass of water 3x a day. This also helps to keep me much more stable. When I added sodium carbonate to this mixture sometimes it also helped with over-anxious thought patterns, and to calm the brain down. I hope this helps someone like it did for me. Peace and love. Cordell

Multiple Supplements
Posted by Candance (Nebraska) on 12/13/2016

The regiment I had posted in the original post was working then everything got worse.
We have since found out my son has Mast Cell Activation/Mastocytosis.

What is Mast Cell Activation....
This may not be the technical terminology, but this is what Jeff deals with.

Everyone has mast cells, it is what gets triggered when you get stung by a bee or are exposed to pollen or other allergens.
The mast cells get activated and release histamine in response. Hence the anti-histamine medication.
There are mast cells everywhere in the body even in the brain.

When someone has Mast Cell Activation (MCAS). The mast cells inappropriately are releasing histamine and can be triggered by about anything. Think about the bubble boy who had to live in a bubble because he was allergic to everything. But now take it a step further, because the mast cells in MCAS do not even need a trigger but add a trigger and things start going haywire. The hard part with this illness since there are mast cells everywhere in the body, the symptoms can be varied and effect different parts of the body, making it very hard to diagnosis.

You may have severe gut pain, swelling in the abdomen, chronic diarrhea, vomiting, skin flares, rashes, itching of skin, sores that take forever to heal, blood pressure issues, swelling of different parts of the body, tongue, throat, face, lips etc, depends where the mast cells are getting with the program. Then there can be seizures with nothing showing up on eegs. Numbness of body extremities making it difficult to walk, clumsy and unstable on feet and in son's case, dropping stuff all the time.

It can cause hypothyroidism, blood sugar issues, susceptible to infections, sometimes one right after another. It can effect the lungs and cause asthma. It can also cause the joints to become disjointed easy which usually ends up with a diagnosis of ehlers daniels syndrome. Two of the worst symptons in my book is the anaphylaxis shock that some people experience on a far to often basis and the mental symptoms which can be anything from, ocd, hallucinations, delusional thinking, fight or flight, mild confusion and agigtation. Which in turn makes it almost impossible to get anyone to take you serious about your wild varied health issues, it is chalked up to your mental state...its all in your head. In turn causing more stress because after years of no one and most importantly the doctors, believing you, you develop PTSD from going to doctors and not being taken serious when you are actually are really suffering horribly everyday. Losing friends and family members because they give up on you or think you are just out of your mind.

Then to make matters even worse, people with MCAS react to most fillers and dyes used in medications. Many people need to have medications prepared by a compounding pharmacy to avoid the fillers and dyes. But until you identify what you are dealing with the medications prescribed actually can and usually make you worse. A horrible vicious cycle. It may sound crazy but some people with MCAS, wish for anaphylaxis type shock just so the doctors will take them serious. It is pretty hard to ignore there is a problem with someone that is going into anaphylaxis shock several times a week.

What is wild, I have not even hit on all the symptons of this illness. But the good news is there are clincal tests they can run to identify the illness. The hard part is the medical field is so compartmentalized, it is hard to get the doctors all on the same page and looking at the patient's complete medical history and issues to see that no person is so unfortunate to have 7 or more separate medical problems and there might be something else behind this causing all this.

My son had/ has the following medical diagnosises in his records
Schizoeffective Disorder
Tramatic Brain Injury ( I might add with no trama to the brain ever taking place)
Possible temporal lobe epilepsy
Anaphylaxis shock to demerol
Paresthesias of the extremities
Chronic athletes foot not responding to treament 15 plus years
Myofascial pain syndrome
Inflammatory neuropathy
Adrenal insufficiency
Double vision (forget what the eye doctor called it)

I forgot to add some of the triggers for this illness, which really make this illness hard to live with and usually is what separates you from friends and family. Mainly because while all the below maybe a trigger, it all depends on what you have been exposed to that day. It is like a bucket. Maybe you are exposed to an odor, then add a bit of stress, then a food. Each time your bucket gets fuller. Its when the bucket overflows is when you start seeing reactions. So you may get away with eating an item or being exposed to some odor today, but tomorrow it might be the item that overflows your bucket. Hence you are faking it, or just over dramatic about your sensitivities. You ate it yesterday, or I came over yesterday and what ever was ie, perfume, hair products or dryer sheets did not bother you. So you obviously are just making this up.
Cleaning products
Voc's in carpet, building materials etc etc
Stress ( sometimes as simple as a coversation or answering a question)
Vibrations (riding in a car)
Physical exertion
Water yes tap water causes skin reactions and even drinking tap water
Dyes and fillers in medications
About anything and everything can trigger the mast cells to degranulate

Not everyone has the same symptoms with this illness and not everyone has the same triggers.

If you suspect this might be what you are dealing with or your family member is. Find a allergist that is familiar with Mast Cell Activation
and have them test for high tryptase, prostaglandins, leukotrienes and 24 hour histamine levels.

With my son we have found he was reacting to the fillers in medications. Mainly dyes, lactose and casien.
He is now doing fairly good taking LIQUID haldol as it is also a mast cell stabilizer and liquid ativan as it is also a mast cell stabilizer. And he is drinking stinging nettle and holy basil tea. Dye free benadryl has become our rescue med.

I hope this helps someone.

Medications, Help for Schizophrenia
Posted by Joseph A. (Stockton, Ca) on 09/18/2021 75 posts

I will discuss Schizophrenia, schizoaffective.

Many on this site are familiar with Dr. Abrams Hoffer and his formulas. Please be advised that I will add a few names of Dr's that did work with Dr. Hoffer and were close friends.

Dr. Michael Lesser, resides in Berkeley hills, Ca., 510 845–0700, resides at 181 Vicente Road, Berkeley, Ca 94707, he and Dr. Hoffer were close. Dr. Lesser works out of his home today (9/18/2021). I brought my son there for 3+yrs, learned a lot, and even helped the Dr with alternatives medicines and supplements. He teaches Orthomolecular medicine (same as Dr. Hoffer). You may want to contact him. His book is “The Brain Chemistry diet. Dr. Michael Lesser.

Another Ph.D. is Andrew Saul, his book is Orthomolecular medicine for everyone, Dr. A. Hoffer also named in the book. All three Dr's recommended B3 Niacin, the flush type, not because it is cheaper but because it helps cholesterol levels. The other B3 Niacin is called Niacinamide, much more expensive and doesn't give a flush. If you get a flush, do not take a shower or bath once you take pills for at least 1 hour, or you can take one aspirin before taking pills. B3 must be taken with food, it reduces the chances of a flush. Start low amounts and double amounts every 2 days. Once you take a few 1,000mg of Niacin without a flush, you can increase a few more thousands with no flush occurring. B3 was primarily given for Auditory hallucinations (AKA: Voices) you will learn that most people who have Schizophrenia, will deny it. Do not get someone with Schizophrenia angry.

Do not eat sugar or foods that have sugar such as carbs, they turn to sugar once eaten. Pastries, white rice, all white or whole wheat products, pizza, pasta, etc., Do not drink 100% juices, none even orange juice, apple juice they are loaded with Sugar, Sugar is your enemy if you have schizophrenia.

Schizoaffective just means you have Schizophrenia and mood changes. It is a Disability. You are entitled to Social Security, if you have ever served in the military you are entitled to a non-service connected 100% disability with AA (Aid and attendance) that means you're entitled to higher monthly payments because you may have to pay for someone helping, assisting you in everyday life. I saw what Antipsychotics do, yes they help a sick person become clinically normal in 2-3 days, that is fine, however, that is when they should then be placed on Orthomolecular medicine (mega doses of supplements) and stop the drugs.

The drugs such as Antipsychotics (Risperdal) usually will give you Tardive Dyskinesia (uncontrollable movements of body parts, especially tongue darting out of the mouth and or jaw moving back and forth, slurred speech. If just being placed on Antipsychotics please take 15 or 20 mg of Manganese daily. It has been found to have a tiny fraction of patients contacting the Sick Tardive Dyskinesia, which will be used to get onto more medications. If you have Tardive Dyskinesia (TD) then take 20 mg manganese 3X daily. Google the correct amount. There is a study you can google regarding the name of the study which used thousands of patients and hundreds of Dr for 15 or so yrs to learn about taking Manganese and not contractingTD.

The study I think was called Dawkins or a similar name.I have all names but am tired but will try to finish before I go to sleep. I know you people will appreciate my help, I am a single parent and have helped my son who is 53 and was diagnosed in 2007 with chronic paranoid schizophrenia. There is a younger Dr named Amy Bader, 800 738-7303, very sharp and nice. I will insert this piece regarding conventional medicine, they treat symptoms only and have many side effects, find, search for alternative meds, supplements that treat root of problem minus any side effects.

Antipsychotics will shorten a person's life but 15-25 yrs if taking long term. They can cause hypertension, diabetes, heart disease, etc., I placed my son on Serpina (Indian Snakeroot) once I stop all medications because they interact with antipsychotics. They help anxiety, calmness, psychosis, and much more you can contact me for help, there is no fee. Serpina tablets are great for insomnia also, just don't take them with antipsychotics. Dosage if the patient is very ill, sick him/her 3 pills in AM and 3 pills in PM once they are doing better you can reduce to 2pills daily 3X daily. Amazon sells 100 pills for $7 (each pill is 4 mg) when giving medication daily I myself would give the same amount of B3 and Vit C. 2,000mg B3 3X daily (6,000mg) then Vit C would be 2,000mf Vit C 3Xdaiky. Do not use sustained or timed release Vit C. You can give the Manganese dosage which is 20mg 3Xdaiky if has Tardive Dyskinesia, if doesn't but is just starting to take then give 15 or 20mg 3X daily. Magnesium Glycinate 400mg or you can apply Dr. Carol Dean's lotion of Magnesian anywhere on the body. Zinc, Vit D (most of USA population are deficient in Vit D, so give Vit D 5,000iu for a month, then reduce to 2-3,000 IU daily. In the winter months, no sun you can give 5,000iu daily, during summer reduce back to 2-3,000iu daily. B-Complex 100mg daily is a must. Zinc, I will stop here because I am exhausted, need to sleep.

You can ask Deirdre for my email address if you have questions, let her know I said it was alright to give out. My son has Schizophrenia, OCD, then the secondary problems, dry mouth agoraphobia, Depression and etc., please google all medications because of side effects, if you have a Dr that just follows what she was taught in school that is not good. They will just give you more (increase) of the same medications.

Never stop cold turkey from medications, can cause problems, seizures, etc., once placed on medications google alternatives that do same thing minus major side effects, I may be able to help there. My son excelled for 8 yrs with No medications while having schizophrenia, then he contracted OCD and they gave him Antipsychotics so I stopped Serpina because they interact. He has TD now, I was able to give a formula that reversed it for years, but now I tried it again, but didn't work.

Currently trying 10mg melatonin. Anxiety pills are L-Theanine with Suntheanine 400mg 2Xdaily. I was giving AcetylL-Carnitine 500mg which worked great for Anxiety but he got the rare rash and I stop. Smoking cigarettes doesn't help nor does drinking alcohol with Schizophrenia medications.

Please don't take Gabapentine, very Dangerous, especially the side effects. If given Valiums (Benzodiazepines) “Do not take longer than 4 weeks, they are addictive, the Dr will say they make you dependent but that's a dangerous word game, my son is addictive after 5 yrs, we were never told, I learn the hard way. Tapering off Valiums is very Dangerous, painful, therefore Google all drugs (medications they call them, ugh! ) if you Google lawsuits you will learn that Big Pharma pays out billions annually, then they laugh all the way to the Bank with $7+ billion earned. They place profit over the health of people.

Joseph A.

Posted by Cordell (Minto, New Brunswick, Canada)

I would like to share a remedy I successfully used to cure schizophrenic thoughts. I was always shy as a kid, and little bit "paranoid" I guess you could say. But when I turned 24 I gradually began to have more paranoia, coupled with anxiety, and sometimes felt I was hearing voices. No, not the audible kind that people usually hear, but more or less I felt there were more thoughts in my head than my own; too many to deal with at once. Some very hateful thoughts had emerged and I sometimes became obsessive over certain angry thoughts, feeling like I couldn't relax and eventually would have a panic attack and feel out of control, possibly cry from too much stimulation etc. I soon found myself trying to figure my thoughts out, but they often made no sense, and I would play psycho-analytical games with other people thinking I realy knew what they were thinking about me. I was always suspicious, and eventhough I didn't want to feel this way that's what happened. Anyway, I know there are others out there that share a similiar story: how they once felt normal than started having some sort of mental illness, be it brain fog (which I also had from the obsessive paranoia), or adhd or whatever it may be. Niacinamide could be the answer to your problems.

On the advice of Ted, a famous contributor to this site, I began taking 2000mg - 3000mg of Niacinamide (niacin can be used, but the flushing may become too annoying at such doses for some people). I noticed within a couple days my excessive paranoid thoughts dimnished almost completely, but I continue to take 500mg tablets everytime I feel them coming back. I also continue to take at least one B 50 tablet a day to prevent deficiencies. It works~

! I realize not every form of schizophrenic thoughts may be cured this way, but its worth a try for anyone seeking help like I did. High doses of niacinamide have cured my excessive anxiety, paranoia, schizophrenic thoughts, and even helped to solve stomach ailments I have had for years along with keeping myself more alkaline. The alkaline remedy I used with most success in over-acidity was 1/4 sodium bicarbonate, and 1/4 potassium citrate (a 99mg tablet) in a glass of water 3x a day. This also helps to keep me much more stable. When I added sodium carbonate to this mixture sometimes it also helped with over-anxious thought patterns, and to calm the brain down. I hope this helps someone like it did for me. Peace and love. Cordell

Niacinamide and Lysine
Posted by Mary (Buenos Aires, Argentina) on 01/16/2014

I cured my son from schizophrenia with Niacinamide B3 and Lysine under Ted's advice. Took 4 months but he was reacting really well from the beginning. It worked and I was able to take him of all meds. I now have a perfectly normal, well balance wonderful kid. His psychiatrist thought I was nuts but it worked!!!! And he is not medicated!!! I had all my prayers answered. Thank you Earth clinic!!!

Now I am healing myself form colon cancer. Declined Chemo. healing naturally!!!

Niacin, Vit C and Red Pumpkin
Posted by Payal (Ca) on 10/30/2018

Cure for Schizophrenia - Hello Everyone based on extensive research and after having read tons of books and having a close relative suffer from this, where Niacin and VIT C could not be administered and patient refuses to be any schizophrenia medication. I think we have a CURE in


Please read and understand this very very carefully. Red Pumpkin is the only known source of the highest levels of all kinds of anti-oxidants and polyphenols and free radical scavengers. At least 1 cup of Red Pumpkin daily - more severe cases may need more. Why do I mention Red Pumpkin.

Schizophrenia is a very very complex brain disorder. In most of the advanced countries like United States, doctors who treat patients for schizophrenia need to put them through a variety of tests - blood tests to check levels of various minerals, vitamins, copper, check for methylation, oxidative stress and polyuria and many many more. So when allopathic medicines are prescribed, patients are usually prescribed anti-psychotics and they are given at least 2-3 different medications to address various conditions. Soon the medicines do not work and need to be replaced by another set of newer medicines. If the patient tries to switch to orthomolecular treatment, even then he needs to be on 10-12 different vitamins eg Niacin, B vitamin family B12, B6, B9.B1.B2, Folic acid, Vit C, Magnesium, Zinc, Calcium, Selenium and the list goes on.

In many cases patients either forget to take this bunch of medicines or their families and caregivers are quick frankly fed up. It is very very difficult and tiring and burdensome for families to cope with scizophrenia, its effects, the patients moods, aggression, behavior and non-productive ness for an entire lifetime.

RED PUMPKIN - and all of you can google this on nutrtion and you and other websites. Red Pumpkin has the exact correct proportion of all the possible vitamins needed for schizophrenia or any other mental illness CURES. It has all the vitamins, minerals and antioxidants VIT A, C, E and polyphenols including beta crypto xanthin which after considerable research is available in plenty in RED PUMPKIN and not in any other vegetable except small amounts in cucumber and water melon.


I highly recommend Dr Abraham Hoffer's remedies on Niacin, VIT C

In addition please use daily doses of RED PUMPKIN - somehow the high anti-oxidants and polyphenols scavenge the BRAIN of free radicals, reduce the oxidative stress and get the dopamine and other neuro transmitter levels to normal.

You should see changes within 24-48 hours.

Please spread this message to everyone else you know and also please post your feedback.

Thanks and God Bless.

B-3 Vitamin Therapy
Posted by Beth F (Ga, ) on 02/10/2016

Hi Barbara..thanks for the info...may be getting a client soon with a schizo diagnosis we are all on a gluten free and natural diet. Think, your rec's may help...we use coconut oil for a grandson with severe ALC. addiction...he's returning to normalcy...the coconut oil attaches to the opioid receptors in the brain and balances the mood/ grandson requests it so I hand him 4 out the door ..on his way to work each day. He's been on vodka 20 yrs, ...type in coconut oil for alcoholism...a great Doctor cured himself...and now fixes others,

Blessings, Beth.

Multiple Supplements
Posted by Joseph (Stockton, CA) on 06/22/2021 75 posts

This comment is directed to Candace,

I too have a son (53) with schizoaffective (2007) I wish I could send you some of my paperwork regarding similar things that your working on, but we're not allowed, therefore I will type to you what I have and have been doing. My son was diagnosed with chronic paranoid schizophrenia in 2007, 6 weeks in VA hospital, then returned home for 6 weeks and I saw what Antipsychotics were doing to him.

He gained 50lbs, slept 18 hrs daily. I was a retired SF, Ca cop, had no formal training in Schizophrenia, went to the library and read all I could & took notes. I immediately stopped ALL medications that were prescribed, Especially the poison of Antipsychotics. I had him taking about 90 pills total daily, many were tiny Chinese pills, etc., as my son improved I got more involved with Orthomolecular Medicine.

This is what I gave: B3 Niacin 4,000-6,000mg; Vit C same dosage; B-Complex 100mg, Vit D3,5000iu; zinc 25mg, L-Theanine 800mg (400 AM- 400 PM) and then his Antipsychotic drugs.

Eventually I contacted a Dr Michael Lessor (84yrs old now) hee was great friends with Dr Abrams Hoffer, both Jewish and worked together, he added a few more supplements & I learned a lot from him after 2.5yrs (retired living in Berkeley hills, Calif.)

I stopped seeing Dr Lessor (a long drive) and started using Serpina, which is my greatest find, a former blood pressure medication from India in 1934. Dosage: 2 4mg pills 3X Daily (6 pills) then I changed to: 3 pills morn, 3 pills at nite (always 6 pills daily), after time I changed back to 2 pills 3Xdaiky, he excelled for about 8 yrs, no one knew he had schizophrenia.

Then he contracted OCD, that was another nightmare, after keeping him home and giving many formulas that just didn't work for him I had to bring him to VA hospital and they immediately gave him Prozac, Risperdal. I had to stop Serpina because they interact. I reduced his 6mg Risperdal to 1.5 mg, and he contracted Tardive Dyskinesia, (Severe) he stayed in the house, Agoraphobia set him.

His Dr was/still is an idiot, so I gave him a formula of BCAA (branch chain amino acids) plus B6 300mg divided dosage. In 5 weeks he was significantly better. I stopped my formula and TD returned, I put him back on the same formula, once he got better again I continued for 3 months then stop, this allowed him not to relapse.

Today he is okay but my goal is to remove Antipsychotics and put him back on Serpina. He is now addicted to Valiums (Diazepines) thru no fault of his and having Severe Anxiety Attacks. (Candace I will leave you more info at the end, ) he can't be tapered off until Anxiety stops and I have nothing to fight his Severe Anxiety (can't give him Valiums) and tapering off is painful & Dangerous, relapses can occur years later, etc.,

I recommend you give your son 15mg Manganese 3X's daily (45mg) while he is taking Antipsychotics, this may prevent him from contracting Tardive Dyskinesia. If he contracts TD start with BCAA 1,000mg 3Xdaily for Week 1 and give him B6 100mg 1pill 3X daily. Week 2 increase BCAA to 2,000mg 3X's daily and give B-Complex 100mg in morning. Continue that, I think on an empty stomach with BCAA, just Google that question. I have the info somewhere here but want to send this to you right away.

Ultrasound improves brain performance (non-invasive)

TMS Transcranial Magnetic Stimulation is very expensive and it appears to really help, however it did not help my son.

Please Google any new supplements or alternative treatments until you google for interactions.

NAC N-acetylcysteine is a supplement form of cysteine, good for Brain Health. NAc helps replenish Glutathione, your body's most powerful Antioxidant. It's antioxidant properties also combat other ailments caused by oxidative stress, such as Heart disease & some Psychiatric conditions.

Ketamine is available, fights Anxiety in a few hours versus 2-4 months before medications fully kick in.

NAC may also alleviate symptoms of multiple psychiatric disorders & reduce addictive behaviors.
marijuana may help fight Anxiety, and the voices but is very addictive after long- term use.

voices, ear plugs can muffle voices, headphones.

Do not consume Sugar or Sugary products.

Voices, my son communicates with (3 voices) does not believe he has Schizoaffective as well as many others.

If you talk to your son and he doesn't answer it is because he may be communicating with the voices and not disrespecting you.

Please don't argue or fight with him.

Mulungu pills help fight anxiety and brings calmness

Jujube Asian fruit is supposed to help, I am curious, just can't afford all options.

Schizophrenia may in part be caused by immune system dysfunction a new study reports. Treatment with Methotrexate a drug commonly prescribed for autoimmune disorders in produced “Positive effects” against some prominent Schizophrenia symptoms.

I will end here, but still have more to share.

Earth Clinic Staff, is there no way of ever communicating with another member directly if both parties agree? Thank you, love your site. Joseph

Multiple Supplements
Posted by Candance (Nebraska) on 03/19/2015

I have a son that has Schizoaffective Disorder. Over the years we tried the orthomolecular medicine based from Abram Hoffner's research. I was taking my son to Pfeiffer Treatment Center in Napersville, Ill. and he was taking compounded supplements based on the tests they had taken. We really saw no improvement over a 2 year period. My son has been on a gluten, dairy, soy free diet for 10 years. No junk foods, coffee, caffeine and strictly organic, GMO free. He has been on either invega or abilify all this time and they have never really quieted the voices.

Just recently I started doing more research and I have found is some new research that looks fairly promising.

"Glutamate is the main excitatory neurotransmitter in the central nervous system. Dysfunction of the glutamatergic system plays an important role in the pathogenesis of schizophrenia.

Schizophrenia is associated with low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death.

It is observed that biotinidase, which maintains biotin levels, is very sensitive to oxidative stress."

So with the above in mind, I started to research what would effect the Glutamatergic system and also the beclin-1 and also help with oxidative stress.I discovered they have been running some trials using Sarcosine and N-Acetyl Cysteine.

"Sarcosine (N-methylglycine) is a naturally occurring GlyT1 inhibitor that has been used in early clinical trials in Taiwan. Initial studies with sarcosine showed efficacy similar to - and in some cases better than - that of direct glycine/D-serine site agonists when added to first-generation or non-clozapine second-generation antipsychotics. Sarcosine also has been found to be effective for acute treatment of schizophrenia."

One study administered N-acetylcysteine, a glutathione precursor, as a potential treatment for persistent negative symptomsEncouraging clinical results were observed in this double-blind study, along with improvement in negative symptoms, and overall functioning.

To address the low levels of Beclin-1 in the hippocampus of the affected which causes diminished autophagy which in turn results in increased neuronal cell death. I found that Trehalose reduces p62/Beclin-1 ratio and increases autophagy in the frontal cortex of ICR mice, possibly by increasing Beclin-1.

"biotinidase, which maintains biotin levels, is very sensitive to oxidative stress"

To deal with the Oxidative stress I have found that Cold Pressed Krill oil and astaxanthin appear to be the best course of action I can find.

So to sum it up...

This is our new course of action:

1,000MG twice a day of Sarcosine and N-Acetyl Cysteine via Profrontal a natural product designed to support
NMDA Receptor function

1250 MG Cold Pressed Krill Oil

4 MG Astaxanthin

Trehalose ( sub-lingually ) Not sure on the dosage of the treholose yet

We where going to try CBD Oil (cannabidiol) as they had a very promising clinical trial in Germany where the CBD Oil had the same effects if not better than the typical anti-psychotic medicine without all the side effects of anti-psychotics. BUT the cost would be a minimum of $1,500 a month and only be available in states that had legalized medical marijuana. Yes, you can buy CBD Hemp oil via the mail but the quality and source is very questionable.

I will update my post going forward if we see improvement.

B-3 Vitamin Therapy
Posted by Graham (Uk) on 01/03/2014

Please google Dr Abrahm Hoffer and his use of Vitamin B3 Niacin (must use the type that gives the flush).

I have used this with my mother when she was diagnosed with Schizophrenia and the results were nothing short of miraculous.

You will also find a lot of information on this site about Schizophrenia and Vitamin B3.

Multiple Supplements
Posted by Cure4schizophrenia (Tallahasee, Fl) on 10/15/2010

Hi, I was diagnosed with schizophrenia at age 18. The disease was very disabling for me, and ruined a few years of my life. The whole time I was on meds I was ALWAYS tired. I always felt terrible, and I was never "truely" well. For example, although I was on medicine, which was the "approved approach" for treatment by modern medicine, I still frequently had delusions. Although I was diagnosed at age 18, when I had my first episode. When they told me what I had, I didn't believe it and I stopped taking my medicine. I went almost a year without another episode, but finally a little less than a year later, I had another episode. This time I stayed on the meds, and again I never felt right. I always felt terrible. So later I got a job at a GNC. And at first I didn't take any of their supplements. I told my manager one day that I was always tired, and he recomended one of GNC's multivitamins because it was high in B-Complex vitamins. So I started taking it, and I started feeling a little better. I eventually read a book called "Prescription for Nutritional Healing, " which had a section in it for schizophrenia. So I read that section and made a few changes, I started taking a few more supplements. I added ginkgo biloba, fish oil (omega 3's), vitamin C, and more B-Complex. Again, it made me feel a little better, but still nothing spectacular, deffinitely nothing in the realm of "being cured. "

So later, in another attempt to get well, I went back to my book "prescription for nutritional healing, " hoping to find something that I had missed that I could start doing to make me better. Lo and behold, I see in the section for schizophrenia this - "Psychiatrists found a link between schizophrenia and pellegra, a Vitamin B3 (Niacin) defficiency disease. Using large gram amounts of niacinamide to treat patients, they get good results. "

So I though hmmmm, niacin and schizophrenia? So I google searched the words "niacin schizophrenia" in my google tool bar, and several pages came up claiming niacin cures schizophrenia. But another name seemed to be mentioned several times, a Dr. Abram Hoffer. So I searched "Abram Hoffer schizophrenia naicin. " He had a book called "Healing Schizophrenia: Complementary Vitamin & Drug Treatments. "

I bought the book, and in it he claimed to have a high success rate treating schizophrenics with gram doses of niacin. His book was very well written, and gave me hope even before I started on his treatment. Mind you by now I was taking a million supplements trying to cure myself. But after reading this book I added niacin and FINALLY started getting well. So well in fact that after 3 years of not doing anything, I started going to school (college) and am doing VERY well, my grades are excellent.

Here's a full list of what I'm taking and why. A GNC multivitamin, to supply a good balance of vitamins & minerals, which is necessary for proper brain function. Also it's very high in B-Complex, and it's timed release, meaning I get a steady release of b vitamins. B-Complex 50, also timed release, for a steady release of b vitamins. Niacin. 1,000 mg (1 gram) 5x per day, for a total of 5 grams per day. Fish oil for the omega 3's, which is very good for brain health. I take 2,100 mg daily in divided doses. Ginkgo Biloba, enhances blood flow to the brain. Ester-C. A supurior form of vitamin C. 1,000 mg with breakfast and dinner. Vitamin E, 400 IU for the antioxidants. Alpha Lipoic Acid, because it regenerates Vitamins C & E after they've nuetralized free radicals. Magnesium, a good brain vitamin. Biotin, since I take so much of the other B vitamins I take a lot of biotin too. Manganese, enhances the action of the B vitamins. Vitamin B12 (Methylcobalamin), best form of B12, most absorbable form. 1000 mg twice daily

Folic acid. Vitamin B6 300 mg, a lot of schizophrenics have a condition where zinc and b6 bind and are excreted in the urine, making them deficient. I think it's called pylloria. Zinc, because of pylloria. Flax Seed Oil, VERY potent in Omega's 3, 6, and 9. Great for brain health. So after 3 years of being on meds, and meds alone. I stayed on the same dose of meds. Then after 3 months of being on those supplements listed, I got so much better that I started school, am excelling in school. And had the meds I was on for 3 years reduced from... 1000 mg to 500 mg, and the other one from 60 mg to 40 mg. I highly recomend anyone who has schizophrenia checks out these 2 books, "Prescription for Nutritional Healing" and "Healing Schizophrenia: Complementary Vitamin & Drug Treatments. "

B-3 Vitamin Therapy
Posted by Suzy (Midwest) on 02/10/2017

Hello Barbara, I'm am very happy you are having success with your son. No one knows the horror of mental illness unless they live it day by day. Our son it in the throws of a cycle now, delusional and combative. I wonder, how did you get your son to take niacin? Is he a minor? I believe it works but we are powerless.

Thank you.


Medications, Help for Schizophrenia
Posted by Joseph A. (Stockton, Ca ) on 09/19/2021 75 posts

Part Two - Schizophrenia, a continuation from a few hours ago I posted, remnants and things of interest I forgot to mention.

In helping people and caregivers I have found these things helpful: Mulungu - fights Anxiety, can take with Antipsychotics 400-500mg 2-3Xdaily. Taurine fights Anxiety, may lower blood pressure a little. For insomnia, I used Benadryl 50-100mg, (which increases the risk of Alzheimer's long-term use.)take 1 pill, if you wake up in middle of night you can take 1 more pill to fall back asleep. These are used as sleeping aids that old time Drs prescribed in the 50's 60's. They are non-addictive, safe, however, they may cause memory loss if taken long term. Use sparingly for a few months. For any new medication, you should Google the side effects of medications. You can use Google as your search engine, however they keep records on you. You can use Yahoo, you can use DuckDuck Go it is used same as google but they don't keep track of everything you're searching for.

Teach breathing exercises to loved ones, teach them to inhale thru nostrils and exhale from mouth slowly. This will allow the person to calm down when excited. One never knows what the next day may bring, be prepared for everything. Ayurvedic medicine, Chinese medicine are very good, here is a little info I received this morning. Kottakkai Arya Vaidysasala - Manasamitra Vatakam. It deals with Anxiety, Depression, treating Psychiatric issues, mental fatigue & depression. I will read later. You must learn to be relaxed, calm while helping the individual, remember if you aren't well organized and don't care for yourself then it will be difficult to help others. Tardive Dyskinesia affects all people differently, here is a formula that worked quite well, then years later it didn't help: using BCAA (Branch Chain Amino Acids) take 1,000mg 3X daily (AM, noon, PM) BCAA for 1 week also take B6 100mg 3Xdaily for 1 week. Second week increase BCAA to 2,000mg 3Xdaily, also increase B6-100mg 3Xdaily. Take until you are helped significantly, once that occurs (significant reduction with TD) then continue exact dosage for 90 more days. It is important because it will avoid relapses with TD Tardive Dyskinesia. I learned thru trial, and error, I stop when he was doing great then his TD returned. I had to continue dosage until he felt much better and picked 90 days out of the air and then stop. He excelled for years until OCD entered his life. Today he suffers TD from about 6AM -8:15AM then it is considerably better. I am using 10mg of Melatonin, which also may protect against COVID-19. Manganese taken 20mg daily 3X daily is another formula that may help. The Magnesium lotion is called: Remag….daily hydration 8.0Z Apply 1tsp daily on body anywhere, penetrates well. Supplement tablets aren't always absorbed 100%. Brain foods: Avocados, Brocolli, Blue Berries (All berries are great) Eggs, Dark Chocolate (within reason) Walnuts, Salmon, Sardines, Tuna (albacore) Turmeric. Memory pills: Rhodiola Rosea, Acety-l-Carnitine Energy, alertness, improves memory, may help Anxiety *** I loved it but it eventually gave my son a rare rash, had to stop. EPA improves mood. DHA - 1gram improves thinking skills. That is 1Gram combined DHA & EPA. For sleep: Tart Dark cherries (dried fruit) or Tart Cherrie Juice at health food store. Always search for side effects, many times metabolic syndrome awaits person, which is: high blood pressure, Diabetes, Heart disease, weight gain, Cholesterol increase (this is where B3 niacin flush type helps).

Never give Sleeping pills, addictive, causes night terrors, hallucinations, sleep walking, also known as amnesia drug. Antipsychotics effects: Acetylcholine in the body, the main neurotransmitter essential for memory, learning. Low levels of acetylcholine in the body lead to: blurred vision, hallucinations, mental confusion, dementia, memory loss, and other health issues.

The dangerous Benzodiazepines are known as: Valium, Ativan, Dalmane, Librium, Klonopin, Doral Versed, Restoril, Xanax.

Things that “may help” TMS Transcranial magnetic stimulation. VA will pay ($12,500) may help OCD also. Remember to check his Vit D levels, should be: 30-90. My sons was 22 which is low, most people are low and it can affect other issues. Dr. Peter Breggin 607 272-5328 wrote Medication Madness, an excellent book of medications that can harm you but is issued by many Doctors because they are not trained in Alternative medicines, Supplements and Nutrition. I hope I have helped all people in need of knowledge regarding the terrible illnesses that are out there and not being improved due to profit $$$ of Big PHARMA. Paxil, google, learn how they lied on trial studies then had to pay Billions in lawsuits, fines, yet they laughed all the way to the Bank with Billions in profits. Thank you, Joseph, and Earthclinic for helping to get knowledge out to the people.

Niacin, Vit C and Red Pumpkin
Posted by Payal (Ca) on 11/06/2018


Red Pumpkin or Pumpkin that is yellowish or red inside - belongs to curcubate family. It is available in all stores. The Halloween Pumpkin is orange in color from outside. I meant or referred to Pumpkin - any Pumpkin variety that is yellowish or orangish from the inside because that is a good indication that it is high in polyphenols or beta carotene. I apologize that I used the word RED - no I meant the regular pumpkin we use which is orange or yellowish hue once its is cut open.

Niacin, Vit C and Red Pumpkin
Posted by Payal (Ca) on 11/06/2018

Hello Everyone,

Just needed to clarify - when I mentioned RED PUMPKIN - I meant the regular Pumpkin that is used in USA or anywhere else, but when it is cut open the pulp or vegetable inside is yellow or orange or deep orange in color. This indicates that it is high in Polyphenols and Beta Carotene.

My research seems to indicate that the very high levels of beta carotene, polyphenols and beta crypto xanthins somehow kind of give a soap wash to the brain and get the neurotransmitters working again.

Another factor I noticed is that Red Pumpkin is high in Copper - Copper toxicity, copper bio Unavailability, any copper issues are linked to Schizophrenia. Somehow the Red Pumpkin seems to magically resolve it and make the patient normal. Its' as though NATURE has provided a tablet in RED PUMPKIN with all the right nutrients in order to treat brain issues.

Please administer and provide feedback - spread the word as well. Thanks.

B-3 Vitamin Therapy
Posted by Mrs. Betty (Colorado) on 04/15/2018

You are so correct about needing to use the niacin that gives a flush. Adelle Davis stressed this mightily. Although the flush is a little hot and itchy, once you build up B3 in your body there is almost no flush at all. My friend hated the flush but we kept reminding of how much better one feels when the nicacin works. Do use the flush niacin. The results are excellent.

Almond Milk
Posted by Afsoon (Tehran, Iran) on 08/24/2012

I just heard this remedy that is useful for Schizophrenia and even for other psychiatrist problem such as depression, OCD, anxiety.

U should drink 4 glasses of it every day. This drink should contain 15 almonds 1 glass of water 1 table spoon of natural honey. Mix them and drink.

B-3 Vitamin Therapy
Posted by Consius (Rdam, Holland) on 08/03/2012

Hi, I wonder if Ted or anyone else could help me with this one. I suffer from schizoaffective disorder with manias and depressions with psychotic episodes sometimes. I am very shy and as a kids always been and maybe that was the cause of having paranoids or stress factors. Not sure.

I have been doing well for 3 days after using Abilify (15 mgs). I feel the meds cause me irritation, sleepyness and sometimes I feel like anxious and not well. I am 35 years old now. I practice meditation to ease the thoughts and be calm.

So I started one day finding a cure for schizophrenia online. I found abram hoffer and his b3 vitamin therapy. I found out that for the illness I should use the following supplements. Correct me (ted or others) if I am wrong:

- 3x 500mg or 3 x 1000mg b3 each day (niacinamide)
- b-complex...... 50 or 100 ( not sure which one)
- vitamine C (ester-c), 3 x 1000mg
- magnesium.. 400 ( at night to sleep)
- zinc: 30 mg ( in case of pyroluria)
- selenium; dose is unkown for me (works well with all B vitamins, not sure)
- manganese ( in case of tardive kineasea)
- vitamin E (anti oxidants)

So, I am not sure if I can leave away the selenium and vitamin E. I eat healthy food and no sugar at all. thanks

B-3 Vitamin Therapy
Posted by Tf4624 (Usa) on 05/19/2012

Zinc and Niacinamide- Dr. Hoffer in Victoria, B. C discovered that if you have schizophrenia, you are not crazy, you have Niacin dificiency.

Treatment -3grams of Niacin and Niacinamide a day and zinc. In a couple of months you will go back to a normal life. That's the end of the schizophrenia but you have to continue taking niacin because schizophrenics have a built in deficiency of that vitamin.

B-3 Vitamin Therapy
Posted by Daniel (Orange, California) on 11/10/2012

yes. Im DANNY, and I did post up what I posted , not to long ago, but only to give everyone hear props, nothin more, mS. LansingMICHIGAN... Per say. And if I didnt make to much sense, I honestly tried my best at 7 months in of Dr. Hoffs, treatment. ') So I was still pretty sick, and that was tough.

AND AS TO HOW RECOVERY GOES. ID LIKE TO LET EVERYONE IN, THAT ITS BEEN 11 MONTHS NOW OR SO, AND I FEEL 1000 X BETTER... I still have that stupid brain fog, every morning I wake up and ask my self if I feel wierd 0_o, and even today I still have it.... So, am I cured of schizophrenia.... NO.. unfortunatelly not yet...


i read everyones comments, and I enjoy it. The ideas, the comments, concerns, etc. So I felt as if talking to all of this community, I wanted to give you all a look at my case, or what ever. But in other words.. I feel better every day and I know only a small amount more of time and treatment.. this will be like a cold'...

so everyone once again, I give u all tremendous amount of props. Keep it up. Dont stop. Dont forget to take the supplements. Excersice, look good, EAT WELL!

and I really recomend u all look into brain supplements... Thanks to my mother , I have these pills, just whith what the label says, it makes u feel better. I First tried them about 2, 3 months ago, also adding lecethin in to the whole mix and match of my vitamins, and man o man, my brain really loved it.... ") REALLY. SOME GOOD STUFF, IT SURE HELPED THE HEALING PROCESS ALONG...

So, according to Dr. Hoffer, his treatment should work on anyone, and those who are first timers, should go NO LONGER THAN 2 years and finally hit recovery. =)

yes 2 yrs is a long time.. But IF IM AT MONTH 11 like I said, or 10, AND I ALLREADY TAKE LESS NIACIN, (because now, if I take the full 4 grams a day, ill have a horrible crashing headache the next day, which is indication I took, and have, waay to much niacin in my system, moree than it needss =)) so along the lines of keeping up with the regimine, you'll def. Love life again, no more abyss, you'll look forward to the day where youll only have to be taking a 1gram niacin, 1 vitamin C, 1 zinc , 1 b 6 , and b general 50, 1 lecethin.")

I know I am.... cause I hate popping pills like if it where in style. i hate it...

and I really do meen it, when I say, u should excersice, pretend ur sweating out black tar thats the causing agent of ur schizophrenia, depression or bi polarism, , , cause u really are. , , that should speed up the healing process....

i have drug induced schizophrenia... so I was extremely dirty, and still, but, and so, I can only speek as to my case...

u all have a good day. =)

B-3 Vitamin Therapy
Posted by Lily (Bc canada) on 10/18/2020

I was first introduced to Dr. Abram Hoffer's work in 1964 while attending a psychology class at University of Sask. in Saskatoon. Soon after, I attended a public lecture that he held. I have studied his work along with Dr. Linus Pauling who was awarded 2 Nobel Prizes for his work. I have met 2 people who were vastly helped by using the vitamin therapy. Also, my nephew as he entered his teens was seen in Victoria BC and followed the therapy & has had a wonderful result.

Multiple Supplements
Posted by Pippa (Uk) on 03/14/2018

When I read your post about mast cell activation, my heart missed a beat because it sounds exactly what my daughter may have. For years I have been reading, researching, wondering, hoping I can find what is the cause of her mental health problems. I have had a suspicion it's to do with histamine in some way - when she has an overload of something it triggers this intolerable behaviour, a misconception of reality, paranoia etc. I have noticed that she loves seafood and avocados, and they say that one can be addicted to the very things that harm you.

Unfortunately, her way of coping has been to turn to alcohol- which also affects histamine levels. It is a viscous circle. I am desperate to help her, but don't know where to turn to. I think I may ask her to try the Benadryl.

I will never give up searching for the answer. I just want her to be able to live a normal life . Underneath all this she is a loving, intelligent, attractive girl, but is so lonely trying to fight this alone. There is no help for mental health victims in uk.

Almond Milk
Posted by sandy (il) on 01/16/2021

There are so many good youtube channels which will tell you how to make almond milk. Soak the almonds overnight and next morning you can make it in good powerful mixer grinder. I do it in my glass jar oster blender. But I do not feel the necessity to strain it. If any chunks are there I just use it in smoothies or eat plain. When I blend it, initially I put very little water few spoons, and grind it and then I add required water.

B-3 Vitamin Therapy
Posted by Lily (Kelowna, Bc) on 04/04/2013

Hi Danny, You may want to research & add the OMEGA 3 & Omega 6 fats in good quantity. Omega 3's best from cold H2Ofish , SARDINES , COD Salmon best. OMEGA 6's from Evening primrose oil or Borage oil. Our brains are about 60% fat. Schiz folks are deficient. Zinc, Vit C Folic acid and Niacin help convert the fats into VITAL brain fats. Look up Patrick Holford & his recommendations for Schiz. Good Luck I am a Mom who is concerned just like yours.

Cudos to you for 11 months of hard work. Keep going Dear one.

B-3 Vitamin Therapy
Posted by Charity (faithville, Us) on 06/14/2021


Voices can have many sources. We are body mind and spirit. I had split personality (alters) and you don't hear the parts all the time but then you can hear a lot of them all at once. Like you are having a barrage of thoughts that don't agree. movie insight out is not accurate but insightful. Your spirit man has a different voice than your natural mind. I study a lot and have regained my alters after a few years of hard work and prayer. I also have a spirit man and grow in spiritual insights through it. My natural mind does not know my spirit man and regulates my navigation in natural things like driving a car, cleaning, cooking, sleeping, ect. My spirit man also talks to me about spiritual things and some prophetic things. Voices can be helpful if you know the sources. I will say I have an enemy of my soul that can know what I might think and input in my thoughts and make it sound like my thoughts. That voice is out to make my life hell on earth and keep me unproductive.

I am familiar with drugs and withdrawal and health problems and mental issues. Taper off any addictions slowly to reduce misery as you get free. Blessings, Charity

Help for people traumatized as children. Dissociative identity disorder: healing your inner child / alter / insider / inner pain (

Niacin and Vitamin C
Posted by Waltz (Bangalore) on 12/11/2018


Try taking 200 mg of B6 along with B complex. Niacin or inositol hexaniacinate dose can be as high as 8-12 grams a day in some cases. What dose is the patient taking currently? Also take magnesium supplements at around 800 mg a day.


Niacin, Vit C and Red Pumpkin
Posted by Teena (Melbourne, Australia) on 10/30/2018 235 posts

Hello Payal, I am pleased but not surprised that you have had success with red pumpkin, this site link has had success with home made tincture of fava bean/Broad bean, against Parkinson's, although she limits dosage to minimum improvement and fermented papaya/pawpaw

The fermentation method would benefit from an airlock to avoid significant wastage, however, that is a small detail, she has taken control of her health, using fava and papaya, and has seen results.

B-3 Vitamin Therapy
Posted by Sara (Texas) on 10/15/2015

Hi Barbara from Texas, Can you tell me what Brand of Niacin No Flush you used. Thank you

Multiple Supplements
Posted by Candance (Nebraska) on 10/22/2015

Well, as it turns out we found out after 12 years he DOES NOT have schizoaffective disorder but rather Mastocytosis that can have affective symptoms. Since we started treating that he has been level.

Multiple Supplements
Posted by Lizzy (Jacksonville, NC) on 09/23/2021

It all starts in the gut, Dr. Pedre has a good book and supplements, along with diet for 28 days, works amazing on many many ailments including mental illness.

Multiple Remedies
Posted by Joseph (Stockton, CA) on 06/24/2021 75 posts

Cont., Candace, more info to post for you reg: Schizophrenia. I will list things, you will have to Google unless we are able to send by email.

Sarcosine improves symptoms of schizophrenia, increases memory & develops the capacity to learn. My notes state 1-2G, however, I wrote only 1G for 3-5 weeks, then slowly add 1/4G.

Betaine crosses BBB, in treatment with mice it reduces behavioral symptoms of schizophrenia. No human trials yet, however eventually I will try.

Psilocybin, a single dose offered Rapid improvement in the levels of Anxiety, Depression. Psilocybin, a compound found in psychedelic mushrooms can affect mood & perception to “Regulate” arousal & panic responses. A single dose of one drug can ease anxiety& depression for five (5) years. Hard to read my own handwriting, however, I think you will get what I mean.

Ketamine, FDA approved for PTSD, Depression, Anxiety. 1 infusion lasts 3.5 months.

Skullcap for insomnia. L-Glutamine you have.

Yamuna Jujube, may keep Dr. away when you eat 3 daily. Calms brain, Anxiety. Jujube sounds very interesting, derived from the old jujube candies.

Schizophrenia treatment BXCL 501- reduces agitation in schizophrenia & Bipolar disorder. Dose 120 mg. A sublingual medication. Joseph

B-3 Vitamin Therapy
Posted by Cathy (Tucson, Az) on 11/07/2010

Check out GAPS diet- Dr Natasha Campbell-Mcbride is a physician who developed this protocol to heal her son of autism. She calls mental disorders such as schizophrenia, depression, ADHD, autism, GAPS--Gut and Psychology Syndrome, because these disorders are caused by intestinal disease. When a child is born, s/he may acquire unhealthy gut flora from the mother. Later, if the child is given antibiotics, and/or fed processed foods (including formula), unhealthy pathogenic bacteria take over the gut, overcoming the good bacteria we all need in our intestines to maintain good health. A leaky gut situation occurs, where toxins from undigested foods are leaked into the bloodstream, causing allergies. Nutrients do not get to the brain, and that is why we have symptoms of mental illness.

People with schizophrenia, depression and autism have very toxic bodies and are very malnourished. The goal here is to repopulate the gut with good bacteria, get rid of the pathogenic bacteria and detoxify the body. It's a long process, but there is a lot of information on line and some Yahoo support groups to help. Please check out the websites and you will be directed to other sites related to GAPS that will be helpful.

B-3 Vitamin Therapy
Posted by Lily (Kelowna, BC) on 01/16/2021

A BOOK to acquire if possible (no longer in print) "Spirituality and Holistic Living" by Sister Theresa Feist, the forward is written by Dr.Abram Hoffer. Theresa Feist was treated by Dr. Hoffer back in he 1970's, she was schizophrenic, his treatment addressed various areas of her life, vitamin therapy and diet. HER BOOK is a great guide, she went on become a healer and helped many people thru her clinic in Winnipeg. Lots of good info on vitamin therapy & diet.

B-3 Vitamin Therapy
Posted by Joyce (Joelton, Tn) on 01/02/2010 509 posts

From the Townsend Letter
November 2009

It was nearly 60 years ago when Abram Hoffer and his colleagues began curing schizophrenia with niacin. While some physicians are still waiting, those who have used niacin with patients and families know the immense practical value of what Dr. Hoffer discovered. Abram Hoffer's life has not merely changed the face of psychiatry. He has changed the course of medicine for all time. His 30 books, 600 scientific papers, and thousands of cured patients have yet to convince orthodox medicine....

General Feedback
Posted by James (Los Angeles, Ca) on 11/17/2009


A friend of mine was diagnosed with Schizophrenia a few years ago and has rotated through a variety of medicines, some that have caused him to have dramatic muscle paralysis, others audio hallucinations. What I am finding very important in the discussion of brain related problems like Schizophrenia, is knowing the persons history. I think it's difficult to find cures if people are not listing, sharing, and linking together common causes. What I am finding in my research is that a lot of these brain diseases have overlapping symptoms and are likely being misdiagnosed. Upon further research, I believe he actually has Parkinson's Disease Dementia.

He has problems walking and with balance, his hands tremble and shake, he has problems learning and problems talking. Many people assume that if someone is hearing voices and is paranoid they have Schizophrenia. However the dementia aspect causes the same thing. I only uncovered this after looking into the cause, since I know what the cause of his problem is. I just have yet to find the cure.

1. He he a history of drug abuse: he was heavily into smoking marijuana in high school. He has done other drugs like ACID on rare ocassions. In high school there has been alcohol poisening through drinking liquor requiring a stomach pump. Heavy beer drinking throughout the process to the point of severe alcoholism. Never during this point or after did he hear audio hallucinations, have severe paranoia, or have muscle problems.

2. Escalated severe substance abuse: he started huffing lacquer thinner over the course of a year. Following this time period, he began having audio hallucinations, severe paranoia, and had muscle problems.

3. Violent behavior led to medication: after a violent act of agression and threats of personal harm to himself, he was medicated and diagnosed with Schizophrenia.

4. Mixing drugs: He took his drugs and continued drinking alcohol because he was addicted, even with AA meetings. He stopped his medication.

5. Poor evaulation of hallucinations: It's unknown whether the audio hallucinations began to happen during huffing, of after huffing. If after huffing it would suggest that the brain damage caused ongoing hallucinations afterwards, even as huffing was discontinued. What is known is that while on his new meds, audio hallucinations continue to occur, possibly less frequently, it's hard to define when no proper evaluation ever done.

Theory 1:
It's possible that huffing caused the hallucinations as he huffed, and the new meds cause the current hallucinations to continue. For those that say they have stopped medicating and continue to hallucinate, the question arises of dependency and lingering toxicity in the system of that med. Also the question arises, what would happen if a normal healthy person took those drugs, would they hallucinate? If so it would suggest strongly that the drugs are causing it. Research could be done into the recreational use of these drugs to see if there is any truth in this and to testimonials of people who quick usage that stop hallucinations.

Theory 2: Based on all his symptoms, it appears he was misdiagnosed with Schizophrenia and actually has Parkinson's with Dementia. I've come to this conclusion after not research Schizophrenia or Parkinson's, but by researching Huffing Lacquer. I came across an article of someone else who huffed for was diagnosed with Parkinson's and shown to have it for at least 3 months at the point of diagnosis.

We report the first description of a patient with parkinsonism induced by solvent abuse. Our patient developed parkinsonism acutely, following heavy abuse of lacquer thinner. Her clinical deficits wee indistinguishable from idiopathic parkinsonism (Parkinson's disease) and she responded to levodopa. Parkinsonism has persisted for more than 3 months. Brain computed tomography was normal. Positron emission tomographic studies showed normal fluorodopa uptake and reduced raclopride binding, indicating an unusual disturbance of striatal dopaminergic function. This patient suggests that organic solvents may cause parkinsonism in susceptible individuals."

What this is suggesting is that things you inhale like lacquer thinner, can lead to Parkinsons. This pushed me to research the symptoms of Parkinsons, all things he appeared to have problems with. Showing that a strong comparison of history can help tie together causes and find links, leading to possible cures.

It should also be noted that Celiac Disease is associated with wheat related foods causing intestine problems, that cause nutrient absorption problems. My research showed that almost all beer has gluten in it because they are mostly brewed from malted barley or wheat. This like ties in a series of additional problems like depression and severe anxiety and irratibility.

Theory 3: Many symptoms are actually pre-existing to the disease. If you lookup Schizophrenia, Parkinsons and Dementia, their are similarities. Also they list things like anxiety, feeling uncomfortable in social settings, etc. These are actually things that he felt prior to any hallucinations or any severe issues. This was actually the reason why he started heavily drinking. He stated that it made him loosen up and took the edge off in a social setting. He would drink to talk to women. This theory suggests that many of the symptoms are not symptoms of the disease because they prexist it. It was the huffing lacquer that started the cycle of audio hallucination and paranioa followed by medication that continued it. When forced to stop drinking, the crutch was removed and he was forced to face that underlying issue of anxiety and fear of social situations. It was amplified by his inability to walk, muscle parilysis and inability to talk and think normally that made him even more conscientious. However it was a pre-existing problem that shouldn't be used to define the disease directly because it misleads people and creates an overlapping of disease symptoms and misclassifications.

General Feedback
Posted by Brandon (Baltimore, Md) on 11/17/2009

Basically, in up to 90% of schizophrenic cases, there is one of three underlying problems. It's either undermethylation (high-histamine histadalia), overmethylation (low-histamine histapenia), or Pyroluria.

All of these have been shown to be treatable with mega-vitamin therapy.

4 of the other 10 percent have cerebral allergies which may be treatable with niacin and vitamin-c. The remaining 6 percent are still unknown.

Keep in mind schizophrenia is a catch-all for serious mental illness that is unknown. It's a BS label, because up to 94% CAN be known as to the major cause ( not necessarily the root cause, but science is working on that, day by day), and treated effectively.

Schizophrenia used to be known as insanity, now-a-days it's usually labeled bi-polar, with psychotic tendencies, or something similar. They are looking at effects and symptoms which seem to stem from biochemical imbalances.

It's horrible that society tends to demonize and/or immoralize these individuals for something that they were most likely born with!

Also, if you check into the occurrences of schizo/insanity before and after the industrial revolution, you will see a clear sharp rise! This gives way to an understanding of how heavy metals and hardcore pollutants used in industries, interact with genetic anomalies to bring about these diseases.


B-3 Vitamin Therapy
Posted by Shaynna (San Diego, CA) on 02/29/2008

Like john was saying about this vitamin, good for SZ and Bi-Polar, Depression, ect. I found on this site that they also say coffee is a source of this. I feel for you all and especially empathize with the lisanna. I have been dating someone with full-blown, ( there are different levels of course) SZ. He is the most wonderful person, brilliant infact you can see the war inside him almost, and I say almost all of the time. She mentioned something about coffee intake with her friend. Almost every friend I know who has SZ, BI-polar, Major Depression are insane coffee drinkers. Could this be a craving? an attempt to compensate? In that site above it mentions coffee a decent source of this. Its terrible though. He gets sick quiet a bit. Alot in fact. And from being with him almost everyday for 3 1/2 yrs. I believe it is the toxicity of his meds. in fact my beliefs where backed up by his doctors sight for med combinations. doctors rate meds and there combinations on a scale of 1-10. To give you an example, i am on Wellbutrin and Seroquel. My level is 6. Possible seizure. His on the there hand is rated a 2! He is on Geodon, Seroquel, and a Hypothyroid medicine. It feels as though his body is shutting down. Like i can feel him wilting inside. This rating of 2 gives to him the possibility of QT'S. These are the signals between the brain and the heart. The possibility that the communication can lapse and his system shut down! If it doesn't restart itself.

Why if it is a chemical imbalance don't we find a wholistic way to balance it instead of forcing the brains chemistry!!! With dir consequences for the rest of the individuals running system!! its as if we cut off there heads to examine it and treat it forgetting there is much more to the individual and in the process, harm them. During this time of me seeing him. We had attempted moving in with one another. Which brought on him becoming abusive towards me. Turning against me. An episode, after episode. He has thus moved back in with his parents. it was hard because, he became semi-physically, definitely emotionally and verbally abusive. At the same time asking for my help, and then turning against himself abusively, for having realizing what he had done and back again. He is a golden person inside but you can see this scenario play out. To see him in all this pain. And as of 2 wks. ago he has had a none-stop migraine which he has been to the ER with, then later to see our doctor who is running tests. And then for an MRA. Our Doctor who is an excellent one. God Bless him, is actually going to send him to an Acupunturist Which brings me to want to type with Lisanna, because she was saying she did this for this friend of hers and it helped quite abit. This is soooo so hard. It also plays a bit of havoc with my head and I hate to say it. Due to issues I have. But I must find a way!!! This is too much seeing this happen to this Extrordinary person.

Here is an incredible sight called 29 causes of SZ. Please check it out. See what you think. I am going to keep on, and keep on doing research. I will let you all know what we find out. Thank God he has such a wonderful family. His poor mother is always worreid sick. And that is another thing for individuals with this, especailly when they realize that their Condition, causes others so much pain, on top of what it causes them. Why does the medicl community believe more in masking problems treating things singularly and not as a whole part of that persons funtionality. Come on guys we can do this. And anybody is welcome to get ahold of me. And PLEASE. Get ahold of me if you find anything, any nuance that you deem worthy, your Logic OR Intuition.......Here is that website. I am absolutely studying into these.

B-3 Vitamin Therapy
Posted by Lily (Kelowna, BC) on 04/04/2013

Dr. HOFFER did not only recommend vitamins and supplements. He also recommended a gluten, dairy & sugar free diet for most patients. It has been well known since the 1950's that wheat gluten can cause various schiz type behaviors. I heard Dr. Hoffer speak at a psych class at the uof S in 1964 also later at a public forum in saskatoon.

DBS (Deep Brain Stimulation)
Posted by Joseph (Stockton, CA) on 06/26/2021 75 posts

This post pertains to Schizophrenia patients who are medication-resistant.

There is now available DBS Deep Brain Stimulation, it is safe, appears to be helping significantly, however there is an implanted device entered deep in the brain. Many patients are turned off by this, yet some want the relief of auditory hallucinations (voices) and will try anything to rid them. Medicare appears to pay the bill of $35,000. The advertisement has not been prevalent therefore I am posting.

Niacin and Vitamin C
Posted by Tay (Boulder, CO) on 06/25/2021

Hi, I too use the Niacin and have for decades. You need to use the Niacin that CAUSES the flush and not the flush free brands or it will not work for mental issues. We learned this the hard way with a family member's illness.

Also, it does not work unless you take the Vit. C with it at the same time.

B-3 Vitamin Therapy
Posted by Rekha (San Ramon, CA) on 04/14/2015

Could you guide me on which book to buy? Dr Hoffer has written several when I googled. Thanks.

B-3 Vitamin Therapy
Posted by Sharon (Miami, Fl.) on 08/23/2012

Hello Consium from Holland: I am doing Dr. Hoffer's B3, Niacin treatment plan with my 20 yr. old son who is autistic and developed schizophrenia in the last year. I found a doctor who follows his program and the first thing he told me was that in his experience niacinamide was not effective in treating schizophrenia so he had me start my son on pure niacin. We started with a 250 mg. Dose increasing by one 250mg pill per day. There was a little bit of flushing as he reached higher levels but really very little.

I know this sounds crazy but my son is up to four doses a day taking a total of 13,750 mg. The doctor regularly monitors his blood to check his liver and kidneys and he is fine. Dr. Hoffer states that, "The keys to taking niacin therapy are quantity, frequency, and duration. "

Here is a link where Dr. Hoffer talks about doses. See page 193, 2nd column, 3 para down.

Dr. Hoffers book, "Niacin, The Real Story", says, "As there is a certain, large amount of fuel needed to launch an aircraft or a spacecraft, there is a certain, large amount of a nutrient needed to cure a sick body. With vitamin therapy speed of recovery is proportional to dosage used."

His book is really excellent and available from in Kindle format. Good luck.

B-3 Vitamin Therapy
Posted by Citygirl27 (Richardson, Tx, Usa) on 08/27/2012

Also, refrain from "flush free" niacin. It is useless and has no effect. The flushing is actually very good for you, super for your skin as well as your veins, among other things.

B-3 Vitamin Therapy
Posted by Rm (Sedona, AZ) on 09/07/2014

Be careful about the form of Niacin you take. Abram Hoffer recommended 1000-3000 mg but of a certain variety. Niaspan or Endura-cin are the best, immediate release is good, with time release the least desirable as it is liver toxic.

B-3 Vitamin Therapy
Posted by Anon (Usa) on 06/09/2018

Coconut oil and its variations, organic, cold processed, get the best you can find as there seems to be adulteration in the industry. Heat a spoonful of the oil on the stove and if it takes on a foul smell use another brand. There is a jar of coconut "butter" that seems best to me. It is nut butter but pureed coconut oil and flesh. Turmeric, fresh if possible (get a blender to make smoothies raw turmeric + fresh lemon juice + sweet fruit like orange to make it taste good). Raw ginger may help. Raw garlic however you can get her to take it. Kefir. Ginko and st. johns wort.

B-3 Vitamin Therapy
Posted by Rose (Md) on 11/18/2021

Thank you. Following Dr Hoffer's recommendation. I tried niacin powder on and off for more than a year. I had a severe allergic reaction. Red from head to foot, blue extremities. Skin itching unbearable, couldn't even touch my skin. Called poison control, it was that severe. But kept on trying, thinking it was the normal flushing reaction. Well after my last try my bil who is a nurse told me not to take it he said I could go into anaphylactic shock. I will now try the no flush niacinmide based on your results.

General Feedback
Posted by Faith (Forest Park, Ohio) on 12/24/2011

The ANSWER is a HIGH FAT DIET, specifically do the Gut and Psychology Diet (GAP) or the Specific Carb Diet (SCD) but add plenty of high fat foods, ESPECIALLY organic coconut oil. The illness is caused by microbes and these diets address the microbes by using meat and bone broths to introduce the minerals that we are missing in our GUTS to heal ourselves. There is a direct correlation between INTESTINAL HEALTH and BRAIN HEALTH... it is what we eat that is making us crazy and anxious and paranoid, etc.

I do want to emphasize though, ORGANIC COCONUT OIL must become a stable in the diet along with olive oil and real butter and raw milk and eggs if you can get them... Try to find a COOP in your area, it will make a world of difference in your health.

The bone broths are cooked all day, for two days in a crockpot. There are various nourishing traditions blogs by people that have plenty of recipes and information on how to make the broths and sites on the specifics of the diets so you won't have to purchase a book if you don't want to...

Please cross-reference this post with other MENTAL/PSYCHOLOGICAL disorders... and for healing of many illnesses.

Here's to a year of better health for us all!

Happy Holidays!

General Feedback
Posted by Slim (Miami Florida) on 01/01/2014

I have been trying to treat my 28 year old son, diagnosed with schizophrenia for 9 years. I have always been a naturalist and did not believe in the harmful medicines prescribed, but he has taken them on many occasions, or been shot up with needles in the Crisis unit of the hosp.

The medicines change very little with him, sometimes surprised that he is the same in 4 days he spent in Crisis unit. His hair test indicates he is not low in Zinc or high in copper. I believe I had the correct test done to show his histamine was within range.

He is talks to himself in about 3 voices, answers back too. He is very uncooperative with everything. I pay him to take the supplements, but cannot get him or afford to pay him more than 1 times a day. Any suggestions

Thanks, Beverly from Miami Florida

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