A lot of my friends thanked me for this. They have been taking condroitin, glucosamine, pain killers but didn't work. I have been having osteoathritis for years on top of fibros dysplasia on the bone of my right thigh and my husband has been having backache and knee ache for so long. Thankfully, I met a very old Chinese doctor who told me to take 6 capsule (1000 mg) of Omega 3 for the first 3 months to get our system used to Omega 3. After the 3rd month, continue with just 2 or 3 (depending on how severe your aches are - I take 3 daily) for the rest of your life. It is probably not a cure but it definitely rid us of the horrible pain on our knees and back, wrist and ankles. And all my friends around my age (50 and above) tried it and they have now just depend on Omega 3 and got rid of their condroitin and glucosamine. Take them in one go. Omega 3 are harmless (they are more of EPO or fish oil) not drugs. Please do not replace Omega 3 with Fish Oil. Fish Oil does not give the same effect and may not work.