Apple Pectin cured Osteo-Arthritis and ganglion cycsts in the small knuckles. The hot-water/ACV soak recommended on Earthclinic was the most helpful topical treatment I ever tried for my painful knuckles. But when I started taking liquid citrus pectin, I noticed more lasting improvement during the day. When I later added apple pectin pills, the pain relief neared 100%. I read where pectin revives stiff, damaged synovial tissue - which is the culprit in ganglions. Doctor's only recommended Glucsoame/chondroiton./MSM, gloves, or surgery! I've tried just about EVERY arthritis supplement out there over the years, (including some fairly exotic and costly ones). But these very cheap, simple and widely available food-based home remedies did the trick for me. It's a shame they aren't more widely known.