I have tried almost every remedy on this site for the last two years to help my melasma: hydrogen peroxide, grapefruit seed extract (GSE), MSM supplementation and horseradish. In addition, I have tried Tri-Luma cream from my dermatologist. I also have worn 50 sunscreen every day from La Roche Posay. Though I appreciated everyone's posts, unfortunately, nothing seemed to work.
Until now. I wanted to share this with everyone on the message board because I found the suggestions here so helpful. Basically, I started taking 200mcg of selenium, a mineral that's supposed to help with Hashimoto's thyroiditis. Within three weeks of taking it, my fatigue had improved AND...my melasma was completely gone. I was shocked and did some research. Turns out that in the same way that yeast overgrowth can affect some people with melasma, there are other people with thyroid problems who are more affected by melasma as well.
(In case the link doesn't work, here the info:Association of Melasma with Thyroid Autoimmunity and Other Thyroidal Abnormalities and Their Relationship to the Origin of the Melasma*
RUB?N J. LUTFI, MIGUEL FRIDMANIS, ALEJANDRO L. MISIUNAS, OSCAR PAFUME, ENRIQUE A. GONZALEZ, JORGE A. VILLEMUR, MIGUEL A. MAZZINI and HUGO NIEPOMNISZCZE)
I should add that I also take fish oil, evening primrose oil and a B vitamin, but the melasma didn't go away until I started with the selenium. HOWEVER, selenium can be toxic at high doses (400mcg)--PLEASE consult with your doctor to find if you are deficient or have other thyroid problems. This probably won't help everyone unfortunately, but those few of you with undiagnosed thyroid issues it may help. And since selenium is quite inexpensive, that's nice too. :)